General Principles of Tumor Immunotherapy : Basic and Clinical Applications of Tumor Immunology
Brings together the world’s leading authorities on tumor immunology. This book describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated through both experimental clinical trials and review of current standard of care therapeutic agents. This information will be invaluable to both students of immunology and cancer research and practicing physicians who have patients with cancer. The book provides a comprehensive overview of the field, demonstrates how advances in basic immunology can and are being applied to cancer, and describes the current status of approved immunotherapy regimens.
General Equilibrium and Welfare Economics : An Introduction
A good basic understanding of general equilibrium theory is a fundamental and indispensable background for advanced work in virtually any sub-field of economics; and a thorough understanding of the methods of welfare economics, particularly in a general equilibrium context, is indispensable for investigators undertaking applied policy analysis. This book addresses these needs and requirements by emphasizing the basic underpinnings of general equilibrium and welfare economics. In particular, the theory of choice, which is fundamental to both areas, is developed in a very comprehensive and rigorous fashion. Moreover, extensive use is made of examples, both of the simple type intended to bolster the student’s understanding of the basic concepts, and those illustrating the application of the material to field areas in economics.
Gene drives at tipping points : Precautionary technology assessment and governance of new approaches to genetically modify animal and plant populations
This book reports on a pilot project aiming at collecting information on the socio-ecological risks that could arise in the event of an uncontrolled spread of genetically engineered organisms into the environment. The researchers will, for instance, be taking a closer look at genetically engineered oilseed rape, genetically engineered olive flies as well as plants and animals with so-called gene drives. The book mainly adresses researchers.
Gender Differences in Computer and Information Literacy : An In-depth Analysis of Data from ICILS
When computer technology was first introduced in schools, there was a prevailing belief that information and communication technologies were ‘boys’ toys’; boys were assumed to have more positive attitudes toward using computer technologies. As computer technologies have become more established throughout societies, gender gaps in students’ computer and information literacy appear to be closing, although studies into gender differences remain sparse.
Gender and migration : IMISCOE short reader
This short reader offers a critical review of the debates on the transformation of migration and gendered mobilities primarily in Europe, though also engaging in wider theoretical insights. Building on empirical case studies and grounded in an analytical framework that incorporates both men and women, masculinities, sexualities and wider intersectional insights, this reader provides an accessible overview of conceptual developments and methodological shifts and their implications for a gendered understanding of migration in the past 30 years. It explores different and emerging approaches in major areas, such as: gendered labour markets across diverse sectors beyond domestic and care work to include skilled sectors of social reproduction; the significance of families in migration and transnational families.
Gastroesophagal reflux disease (GERD)
Gastroesophageal reflux disease (GERD) is a common disease with a high prevalence worldwide and a great socioeconomic burden. GERD is a multifactorial disease in which anatomical and functional factors both play a pathogenetic role. The disease can manifest in various symptoms which can be grouped into typical, atypical and extra-esophageal symptoms. The pathophysiology of GERD is complex and not completely understood. An abnormal LES pressure and increased reflux during transient LES relaxations are believed to be key etiologic factors. Prolonged exposure of the esophagus to acid is another. Heartburn and acid regurgitation are the most common symptoms of GERD, although pathologic reflux can result in a wide variety of clinical presentations.
Game Theory and Mutual Misunderstanding : Scientific Dialogues in Five Acts
This book consists of five acts and two interludes, which are all written as dialogues between three main characters and other supporting characters. Each act discusses the epistemological, institutional and methodological foundations of game theory and economics, while using various stories and examples. A featured aspect of those discussions is that many forms of mutual misunderstanding are involved in social situations as well as in those fields themselves. One Japanese traditional comic story called the Konnyaku Mondo is representative and gives hints of how our thought is constrained by incorrect beliefs. Each dialogue critically examines extant theories and common misunderstanding in game theory and economics in order to find possible future developments of those fields.
Gambling Problems in Youth : Theoretical and Applied Perspectives
Howard J. Shaffer, Ph. D. More than 20 years ago, I first noted that young people in North America were growing up in a context of legalized gambling for their entire lifetime. By the 1980s, for young people, gambling had become an average and expectable part of the social landscape. Amid legal opportunities to gamble in all but two of the United States and with illicit opportunities to gamble in every state, gambling is now ubiquitous in America. With few social sa- tions to limit a young person’s interest in gambling—like their adult co- terparts—young people now gamble in larger numbers and for seemingly higher stakes
Galling Arthropods and Their Associates ; Ecology and Evolution
The book addresses recent developments in the ecology, evolution, systematics, physiology, and biodiversity of gall-inducing arthropods, with individual contri butions ranging in scope from detailed descriptions to profoundly synthetic stud ies. One underlying theme of the book is the various impacts of gall induction that indirectly affect insect communities on the host plant. The other important contri bution is the highly intricate and dynamic interactions between galling arthropods and their uniquely specialized host plants. Included also are chapters that discuss biodiversity and distribution patterns of gall-inducing arthropods, and biological control of invasive gall-inducing arthropods and of invasive trees. We believe that this book makes an important contribution to the knowledge of galling arthropods and their associates and to the development of robust, general principles of the ecology and evolution of these organisms.
Galerkin Finite Element Methods for Parabolic Problems
This book provides insight in the mathematics of Galerkin finite element method as applied to parabolic equations. The approach is based on first discretizing in the spatial variables by Galerkin's method, using piecewise polynomial trial functions, and then applying some single step or multistep time stepping method. The concern is stability and error analysis of approximate solutions in various norms, and under various regularity assumptions on the exact solution.
Fuzzy Modeling and Fuzzy Control
Fuzzy logic methodology has been proven effective in dealing with complex nonlinear systems containing uncertainties that are otherwise difficult to model. Technology based on this methodology has been applied to many real-world problems, especially in the area of consumer products. This book presents the first unified and thorough treatment of fuzzy modeling and fuzzy control, providing necessary tools for the control of complex nonlinear systems.
Fuzzy Logic Applications in Engineering Science
Fuzzy logic is a relatively new concept in science applications. Hitherto, fuzzy logic has been a conceptual process applied in the field of risk management. Its potential applicability is much wider than that, however, and its particular suitability for expanding our understanding of processes and information in science and engineering in our post-modern world is only just beginning to be appreciated.
Fuzzy Logic and Applications ; Vol. 2955 ; 5th International Workshop, WILF 2003, Naples, Italy, October 9-11, 2003, Revised Selected Papers
This volume constitutes the thoroughly refereed post-workshop proceedings of the 5th International Workshop on Fuzzy Logic and Applications held in Naples, Italy, in October 2003. The 40 revised full papers presented have gone through two rounds of reviewing and revision. All current issues of theoretical, experimental and applied fuzzy logic and related techniques are addressed with special attention to rough set theory, neural networks, genetic algorithms and soft computing.
Fuzzy database modeling with XML
Fuzzy Database Modeling with XML aims to provide a single record of current research and practical applications in the fuzzy databases. This volume is the outgrowth of research the author has conducted in recent years. Fuzzy Database Modeling with XML introduces state of the art information to the database research, while at the same time serving the information technology professional faced with a non-traditional application that defeats conventional approaches. The research on fuzzy conceptual models and fuzzy object-oriented databases is receiving increasing attention, in addition to fuzzy relational database models. With rapid advances in network and internet techniques as well, the databases have been applied under the environment of distributed information systems. It is essential in this case to integrate multiple fuzzy database systems. Since databases are commonly employed to store and manipulate XML data, additional requirements are necessary to model fuzzy information with XML. Second, this book maps fuzzy XML model to the fuzzy databases. Very few efforts at investigating these issues have thus far occurred.
Fuzzy Choice Functions : A Revealed Preference Approach
This book extends the theory of revealed preference to fuzzy choice functions and provides applications to multicriteria decision making problems. The main topics of revealed preference theory (rationality, revealed preference and congruence axioms, consistency conditions) are treated in the framework of fuzzy choice functions. New topics, such as the degree of dominance and similarity of vague choices, are developed. The results obtained are applied to economic problems where partial information and human subjectivity involve vague choices and vague preferences. The book contains a number of new results achieved by the author. Even though the text is reasonably self-contained, previous knowledge of revealed preference and fuzzy set theory is helpful for the reader.
Future Interaction Design
In 1969 Herbert Simon wrote a book, The Science of the Artificial, in which he argued that cognitive science should have its area of application in the design of devices. He proposed the foundation of a science of the artificial related with cognitive science in the sense in which we have traditionally understood the relationship between the engineering disciplines and the basic sciences. Such a science has been called cognitive ergonomics or cognitive engineering (Norman 1986). Simon’s cognitive ergonomics (1969), would be independent of cognitive science, its basic science, although both would be closely related. Cognitive science would contribute knowledge on human cognitive processes, and cognitive ergonomics would contribute concrete problems of design that should be solved in the context of the creation of devices. Norman (1986), the author that coined the term cognitive engineering, conceived it as an applied cognitive science where the knowledge of cognitive science is combined with that of engineering to solve design problems. According to Norman, its objectives would be: (1) to understand the fundamental principles of human actions important for the development of the engineering of design principles, and (2) to build systems that are pleasant in their use.
Future campus : Design quality in university buildings
Argues that investment in the higher education sector is a driver for intellectual, social and economic development, offering opportunities for positive impacts for the physical environment on the character and performance of higher education. The editor believes that good outcomes result from good design, which should address elements such as learning from best current practice, the importance of clear briefing, good environmental performance, the positive social impacts and, also, the importance of ensuring a beautiful outcome. It has chapters contributed from leading-edge practices, including case studies with highly illustrated project examples.
Fungal Immunology: From an Organ Perspective
This book will serve as a comprehensive review of all known immune mechanisms for common medically important fungal pathogens. Its novelty lies in the organization: Rather than chapters devoted to specific fungi, chapters are organized by organ system. All other texts in the field, which are now quite old, are arranged according to specific fungi.
Fundamentals of switching theory and logic design : A hands on approach
Switching theory and logic design provide mathematical foundations and tools for digital system design that is an essential part in the research and development in almost all areas of modern technology. The vast complexity of modern digital systems implies that they can only be handled by computer aided design tools that are built on sophisticated mathematical models. Fundamentals of Switching Theory and Logic Design is aimed at providing an accessible introduction to these mathematical techniques that underlie the design tools and that are necessary for understanding their capabilities and limitations.
Fundamentals of Space Biology : Research on Cells, Animals, and Plants in Space
This book is intended as an overview at the undergraduate or early university level and describes the effects of spaceflight at cellular and organism levels. Past, current, and future research on the effects of gravity--or its absence--and ionizing radiation on the evolution, development, and function of living organisms is presented in layman's terms by researchers who have been active in this field. The purpose is to enlighten science and non-science readers to the benefits of space biology research for conducting basic and applied research to support human exploration of space. Also covered are the advantages of approaching the space environment as a laboratory for scientific, technological, and commercial research.



















