الصفحة 28
الصفحة 28
DNA Methylation : Development, Genetic Disease and Cancer
It has become apparent that the genomes of many organisms are characterized by unique patterns of DNA methylation which can differ from genome segment to genome segment and cell type to cell type. These patterns can be instrumental in determining cell type and function. Thus, it is not surprising that studies on the role of DNA methylation now occupy center stage in many fields of biology and medicine such as developmental biology, genetic imprinting, genetic disease, tumor biology, gene therapy, cloning of organisms and others. Once again, basic research in molecular biology has provided the essential foundation for investigations of biomedical problems.
DNA Methylation : Basic Mechanisms
The structural and functional importance of the correct patterns of DNA methylation in all parts of a mammalian genome is not well understood. The stability, inheritability, and developmental flexibility of these patterns point to a major role that these patterns appear to play in determining structure and function of the genome.
DNA manipulation and analysis
Details technologies on recombinant DNA and nucleic acid manipulation that underpin much of the biological sciences and instructions on how to conduct them successfully. Chapters guide the reader through the basics of oligonucleotide synthesis and DNA sequencing; recombinant DNA plasmid work; cell-free experiments and the latest developments in CRISPR approaches to genome modification.
Distributed Embedded Control Systems : Improving Dependability with Coherent Design
Distributed Embedded Control Systems handles the domains encountered when designing a distributed embedded computer control system as an integrated whole. First to be discussed are some basic issues about real-time systems and their properties, specifically safety. Then, system and hardware architectures are dealt.
Distributed Computing and Internet Technology ; 4th International conference, ICDCIT 2007, Bangalore, India, December, 17-20, 2007, Proceedings
The book is covering a range of issues from basic technology, through services and engineering, to applications, from development issues, through middleware support, to actual delivery of e-Society services.
Disorders of the Respiratory Tract : Common Challenges in Primary Care
In Disorders of the Respiratory Tract: the author covers the range of knowledge needed to provide excellent care for patients with respiratory disease, from the basics of pulmonary function testing to understanding and caring for common respiratory illnesses, including chronic obstructive pulmonary disease, asthma, allergic rhinitis, and pneumonia. Less common illnesses.
Disordered Materials : An Introduction
This self-contained text introduces the physics of structurally disordered condensed systems at the level of advanced undergraduate and graduate students. Among the topics are the geometry and symmetries of the structural units used as building blocks of extended structures, the various kinds of disorder, the phenomenology and the main theories of the glass transition, the structure of amorphous systems and the techniques to investigate it, the evolution of system's structure with its size (clusters) and the presence of orientational order in the absence of translational order (quasicrystals). In the second edition, the treatment of the mode coupling theory of the glass transition has been enlarged and connects now to a new section on collective excitations in disordered systems. Special attention has been devoted to nanometer-sized disordered systems, with emphasis on cluster-assembled materials. Questions of what governs the occurrence and stability of quasicrystals, the features of the amorphous to quasicrystal transformation and its reverse transition are discussed. The conditions leading to nano-quasicrystalline phases of technological interest are examined. Throughout the text relevant recent experimental and theoretical results are discussed so as to give readers insight into the currently most vibrant research topics.
Discovering Mathematics with Magma : Reducing the Abstract to the Concrete
This volume celebrates the first decade of the Computer Algebra system Magma. With a design based on the ontology and semantics of algebra, Magma enables users to rapidly formulate and perform calculations in the more abstract parts of mathematics. The book range over much of Magma's coverage of algorithmic algebra: from number theory and algebraic geometry, via representation theory and group theory to some branches of discrete mathematics and graph theory. A basic introduction to the Magma language is given in an appendix. The book is simultaneously an invitation to learn a new programming language in the context of contemporary research problems, and an exposition of the types of problem that can be investigated using computational algebra.
Discoveries in Photosynthesis
Conceived of as a way of summarizing the history of research advances in photosynthesis as of millennium 2000, the book evolved into a majestic and encyclopedic saga involving all of the basic sciences. This book is meant not only for the researchers and graduate students, but also for advanced undergraduates in Plant Biology, Microbiology, Cell Biology, Biochemistry, Biophysics and History of Science.
Direct Methods in the Calculus of Variations
Studies vectorial problems in the calculus of variations and quasiconvex analysis. It is a new edition of the earlier book published in 1989 and has been updated with some new material and examples added. This monograph will appeal to researchers and graduate students in mathematics and engineering.
Direct Democracy in Europe : Developments and Prospects
The initiative and referendum process offers extra channels of participation and can serve as an important supplementary institution in representative democratic systems. This first volume of the new series Direct Democracy in Modern Europe features sixteen systematic and broadly empirical approaches to the study of modern direct democracy within the context of European politics including - system contexts and effects of the initiative and referendum process - theoretical approaches and basic values in modern direct democracy - the quality and institutional design of direct democratic mechanisms - aspects of information and communication - institutional performance and economic effectiveness - transnational challenges and the development of direct democracy in Europe
Dipeptidyl Aminopeptidases : Basic Science and Clinical Applications
Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses, and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes. Leading experts in the field will contribute to this book, which will present a state-of-the-art view on these enzymes at a time when our understanding of their function is growing ever more rapidly and therapeutic options have become imminent. The sections of the book will focus on various topics including DP IV and related enzymes in: expression and function, metabolic disorders, immune mechanisms and immune disorders, neuronal diseases and cancer, and related drug development.
Digital VLSI Systems Design : A Design Manual for Implementation of Projects on FPGAs and ASICs Using Verilog
The book presents new material and theory as well as synthesis of recent work with complete Project Designs using industry standard CAD tools and FPGA boards, enabling the serious readers to design VLSI Systems on their own. The reader is taken step by step through the design right from implementing a single digital gate to a massive design consuming well over 100,000 gates. The Verilog codes developed for these designs are universal and can work on any FPGA or ASIC and are technology independent. The book presents the development of novel algorithms and architectures for optimum realization of high tech. products. All the design codes developed in this book are Register Transfer Level (RTL) compliant and can be readily used or amended to suit new projects.
Digital twin : Architectures, networks, and applications
Offers comprehensive, self-contained knowledge on digital twin (DT), which is a very promising technology for achieving digital intelligence in the next-generation wireless communications and computing networks. DT is a key technology to connect physical systems and digital spaces in Metaverse. The objectives of this book are to provide the basic concepts of DT, to explore the promising applications of DT integrated with emerging technologies, and to give insights into the possible future directions of DT. For easy understanding, this book also presents several use cases for DT models and applications in different scenarios. The book starts with the basic concepts, models, and network architectures of DT. Then, we present the new opportunities when DT meets edge computing, Blockchain and Artificial Intelligence, and distributed machine learning (e.g., federated learning, multi-agent deep reinforcement learning).
Digital Towns : Accelerating and Measuring the Digital Transformation of Rural Societies and Economies
This book explores the digital transformation of small and rural towns, in particular, how to measure the evolution and development of digital towns. In addition to access to resources, competition from urban and global markets, and population trends, rural communities present lesser access and use of digital technologies and have lower digital competencies and skills than their urban counterparts. Consequently, they experience less beneficial outcomes from increased digitalisation than urban areas. This book defines what a digital town is and explores digitalisation from the perspective of the four basic economic sectors in towns - individuals and households, businesses, the public sector, and civil society - and three types of enabling infrastructure - digital connectivity, education, and governance.
Digital Simulation in Electrochemistry
The book shows how to numerically solve the parabolic partial differential equations (pdes) encountered in electroanalytical chemistry. It does this in a didactic manner, by first introducing the basic equations to be solved and some model systems as text cases, for which solutions exist. Then it treats basic numerical approximation for derivatives and techniques for the numerical solution of ordinary differential equations, from which the more complicated methods for pdes can be derived. The major implicit methods are described in detail, and the handling of homogeneous chemical reactions, including coupled and nonlinear cases, is detailed. More advanced techniques are presented briefly, as well as some commercially available program packages.
Digital Signal Processing with Field Programmable Gate Arrays
Field-Programmable Gate Arrays (FPGAs) are revolutionizing digital signal processing as novel FPGA families are replacing ASICs and PDSPs for front-end digital signal processing algorithms. So the efficient implementation of these algorithms is critical and is the main goal of this book. It starts with an overview of today's FPGA technology, devices, and tools for designing state-of-the-art DSP systems. A case study in the first chapter is the basis for more than 40 design examples throughout. The following chapters deal with computer arithmetic concepts, theory and the implementation of FIR and IIR filters, multirate digital signal processing systems, DFT and FFT algorithms, advanced algorithms with high future potential, and adaptive filters. Each chapter contains exercises. The VERILOG source code and a glossary are given in the appendices. This edition has a new chapter on microprocessors, new sections on special functions using MAC calls, intellectual property core design and arbitrary sampling rate converters, and over 100 new exercises.
Digital Signal Processing for Measurement Systems : Theory and Applications
Digital Signal Processing for Measurement Systems: Theory and Applications covers the theoretical as well as the practical issues which form the basis of the modern DSP-based instruments and measurement methods. It covers the basics of DSP theory before discussing the critical aspects of DSP unique to measurement science. Includes important topics, for example, problems that arise when sampling periodic signals and the relationship between the sampling rate and the SNR
Digital Signal Processing : An Experimental Approach
Digital Signal Processing is a mathematically rigorous but accessible treatment of digital signal processing that intertwines basic theoretical techniques with hands-on laboratory instruction. Divided into three parts, the book covers various aspects of the digital signal processing (DSP) "problem".
Digital image processing
Completely self-contained and heavily illustrated, this introduction to basic concepts and methodologies for digital image processing is written at a level that is suitable for seniors and first-year graduate students in almost any technical discipline
