الصفحة 27
الصفحة 27
Genetic testing in reproductive medicine
Illustrates the importance and significance of molecular genetic testing in reproductive disorders. The present book covers the genetic testing in various reproductive system anomalies, including disorders of sexual development, male infertility (Y deletions, autosomal mutations, sperm DNA fragmentation), female infertility (PCOS and POF), mitochondrial DNA testing for oocyte quality, recurrent pregnancy loss, pre-term birth, endometrial receptivity, prenatal genetic screening, reproductive carrier screening, preimplantation genetic screening, endometrial cancer, cervical cancer and other related reproductive health disorders. Microbiome testing and its contribution to genetic testing in reproductive medicine are also discussed. Covers ethical, moral and technical challenges in genetic testing in reproductive medicine. The book aims to set up a standard with regard to genetic testing in the reproductive medicine field, encourage further data generation, and provide food for thought in the areas of lacunae.
Genetic Engineering of Mesenchymal Stem Cells
MSC (mesenchymal stem cells) have been reported to initiate revascularization after injury, to facilitate engraftment of blood-forming stem cells, and to reduce the incidence of graft-vs. host disease through their immune-suppressive qualities. Finally, bone marrow-derived MSC have been reported to home to areas of solid tumor revascularization, and thus may be used as delivery vehicles to target ablative agents into dividing tumor cells. Recently the characteristics of human MSC from adipose (fat) tissue have also been identified. The possibility of repairing tissues, speeding stem cell engraftment, and targeting solid tumors for specific killing, using MSC easily harvested from bone marrow, or better yet, from unwanted fat tissue, holds broad appeal, and is an intriguing possibility that could have dramatic effect on health care. This book has information on how to isolate, grow, and characterize MSC from marrow and fat, and gives important insight into how these cells may be used for gene delivery and cellular therapies in the future. Updates on emerging clinical trials are given.
Generalized Curvatures
The central object of this book is the measure of geometric quantities describing N a subset of the Euclidean space (E ,), endowed with its standard scalar product. Let us state precisely what we mean by a geometric quantity. Consider a subset N S of points of the N-dimensional Euclidean space E , endowed with its standard N scalar product. LetG be the group of rigid motions of E . We say that a 0 quantity Q(S) associated toS is geometric with respect toG if the corresponding 0 quantity Q[g(S)] associated to g(S) equals Q(S), for all g?G . For instance, the 0 diameter ofS and the area of the convex hull ofS are quantities geometric with respect toG . But the distance from the origin O to the closest point ofS is not, 0 since it is not invariant under translations ofS. It is important to point out that the property of being geometric depends on the chosen group. For instance, ifG is the 1 N group of projective transformations of E , then the property ofS being a circle is geometric forG but not forG , while the property of being a conic or a straight 0 1 line is geometric for bothG andG . This point of view may be generalized to any 0 1 subsetS of any vector space E endowed with a groupG acting on it.
Generalized Bounds for Convex Multistage Stochastic Programs
The auther was involved in several industry projects in the field of power management, on the occasion of which I was repeatedly c- fronted with complex decision problems under uncertainty. Although usually hard to solve, I quickly learned to appreciate the benefit of stochastic progr- ming models and developed a strong interest in their theoretical properties. Motivated both by practical questions and theoretical concerns, I became p- ticularly interested in the art of finding tight bounds on the optimal value of a given model. The present work attempts to make a contribution to this important branch of stochastic optimization theory. In particular, it aims at extending some classical bounding methods to broader problem classes of practical relevance.
Gene Expression Programming : Mathematical Modeling by an Artificial Intelligence
This monograph provides all the implementation details of GEP so that anyone with elementary programming skills will be able to implement it themselves. The book also includes a self-contained introduction to this new exciting field of computational intelligence, including several new algorithms for decision tree induction, data mining, classifier systems, function finding, polynomial induction, times series prediction, evolution of linking functions, automatically defined functions, parameter optimization, logic synthesis, combinatorial optimization, and complete neural network induction. The book also discusses some important and controversial evolutionary topics that might be refreshing to both evolutionary computer scientists and biologists.
Gene Expression and Regulation
This book offers a comprehensive look into the science of gene expression and regulation. Focusing on topics such as actions of nuclear receptors, RNA processing, and DNA methylation and imprinting, Gene Expression and Regulation is edited by a leading biologist and includes contributions by experts in the field. Presented in the following five sections, this book covers a full spectrum of topics: The History; The Machinery; The Regulators; The Genome; and Special Topics. The Machinery section covers the transcriptional apparatus and general transcription factors. The Regulators section examines selected gene-specific transcription factors important to regulating gene expression. The Genome section covers issues relevant to the behavior of the genome in relation to gene regulation. The Special Topics section discusses several selected topics ranging from bacterial and plant gene expression to DNA topology and interference RNA. The book’s focus is on scientific concepts and issues, rather than specific organisms or experimental approaches.
Gender, Health and Ageing : European Perspectives on Life Course, Health Issues and Social Challenges
The objective of this book is to provide an overview of gender, health and ageing. Important theoretical concepts, such as life course and "Lebenslagen" in old age, or differences in men's health, are introduced. It is increasingly important to build a European basis of knowledge, to conduct discussions on European research findings, and to develop European research frameworks. In this volume, central theoretical debates on gender impacts on life course and old-age health, and vital issues of health research in the context of gender and old age are introduced. Specific aspects, such as the impact of gender and age on cardiovascular health, elder abuse and mental health, or care between gender relations, gender roles and gender constructs, are pointed out.
Gender and the judiciary in Africa: from obscurity to parity
Addresses the important issue of the increasing numbers and varied roles of women judges and justices, as judiciaries evolve across the continent.Scholars of law, gender politics and African politics provide overviews of recent developments in gender and the judiciary in nine African countries that represent north.
Gases and Toxins that Cause Pulmonary Edema
Pulmonary edema is a major health problem in the lung, it is a cardinal feature of congestive heart failure. Pulmonary edema defined as excessive extravascular water in the lungs, is a common and serious clinical problem. Pulmonary edema can be life-threatening, but effective therapy is available to rescue patients from the deleterious consequences of disturbed lung fluid balance, which usually can be identified and, in many instances, corrected. So we like to talk about this common disease because of its importance and its wide spread around the world. Other important causes of pulmonary edema are human exposure to some gases and toxins, the most important of which is chlorine gas, phosgene, mustard gas, heroin, paraquat and ammonia. This research paper will discuss also the procedures that are included, as well as a wider knowledge of these toxins and gases.
Gap Junctions in Development and Disease
Starting with a comprehensive review of the various mouse and human genes encoding the channel-forming protein connexin, further chapters describe the most important connexin mutations that lead to diseases such as hereditary deafness and female infertility in humans. Erroneous signaling mediated via connexin-protein interactions, thought to be responsible for disfunction of organs such as heart, muscle, brain, skin, lens, placenta, and endocrine tissue in mice and men, is also addressed.
Galling Arthropods and Their Associates ; Ecology and Evolution
The book addresses recent developments in the ecology, evolution, systematics, physiology, and biodiversity of gall-inducing arthropods, with individual contri butions ranging in scope from detailed descriptions to profoundly synthetic stud ies. One underlying theme of the book is the various impacts of gall induction that indirectly affect insect communities on the host plant. The other important contri bution is the highly intricate and dynamic interactions between galling arthropods and their uniquely specialized host plants. Included also are chapters that discuss biodiversity and distribution patterns of gall-inducing arthropods, and biological control of invasive gall-inducing arthropods and of invasive trees. We believe that this book makes an important contribution to the knowledge of galling arthropods and their associates and to the development of robust, general principles of the ecology and evolution of these organisms.
Galaxy Formation and Evolution
An Astronomical Life – Observing the Depths of the Universe” Though science as a subject can be di?cult, what has been more important for me is that its practice can also be rewarding fun! This book is crafted to expose the reader to the excitement of modern observational cosmology through the study of galaxy evolution over space and cosmic time. Recent extragalactic research has led to many rapid advances in the ?eld. Even a suitable skeptic of certain pronouncements about the age and structure of the Universe should be pleased with the large steps that have been taken in furthering our understanding of the Universe since the early 1990’s. My personal involvement in galaxy research goes back to the 1960’s. At that point, galaxies were easily recognized and partially understood as organized c- lections of stars and gas. What their masses were presented a problem, which I supposed would just fade away. But fade it didn’t. Distant active nuclei and quasars were discovered in the mid-1960’s. A c- mon view of QSOs was that they have large redshifts, but what use are they for cosmology or normal galaxy astrophysics? I shared that conclusion. My expec- tions fell below their potential utility. In short, the Universe of our expectations rarely matches the Universe as it is discovered.
Galaxy Formation
This second edition of Galaxy Formation is an up-to-date text on astrophysical cosmology, expounding the structure of the classical cosmological models from a contemporary viewpoint. This forms the background to a detailed study of the origin of structure and galaxies in the Universe. The derivations of many of the most important results are derived by simple physical arguments which illuminate the results of more advanced treatments. A very wide range of observational data is brought to bear upon these problems, including the most recent results from WMAP, the Hubble Space Telescope, galaxy surveys like the Sloan Digital Sky Survey and the 2dF Galaxy Redshift Survey, studies of Type 1a supernovae, and many other observations.
Fuzzy systems and knowledge discovery ; Vol. 3614 ; 2nd International Conference, FSKD 2005, Changsha, China, August 27-29, 2005, Proceedings, Part II
This book and its sister volume, LNAI 3613 and 3614, constitute the proce- ings of the Second International Conference on Fuzzy Systems and Knowledge Discovery (FSKD 2005), jointly held with the First International Conference on Natural Computation (ICNC 2005, LNCS 3610, 3611, and 3612) from - gust 27–29, 2005 in Changsha, Hunan, China. FSKD 2005 successfully attracted 1249 submissions from 32 countries/regions (the joint ICNC-FSKD 2005 received 3136 submissions). After rigorous reviews, 333 high-quality papers, i. e. , 206 long papers and 127 short papers, were included in the FSKD 2005 proceedings, r- resenting an acceptance rate of 26. 7%. The ICNC-FSKD 2005 conference featured the most up-to-date research - sults in computational algorithms inspired from nature, including biological, e- logical, and physical systems. It is an exciting and emerging interdisciplinary area in which a wide range of techniques and methods are being studied for dealing with large, complex, and dynamic problems. The joint conferences also promoted cross-fertilization over these exciting and yet closely-related areas, which had a signi?cant impact on the advancement of these important technologies. Speci?c areas included computation with words, fuzzy computation, granular com- tation, neural computation, quantum computation, evolutionary computation, DNA computation, chemical computation, information processing in cells and tissues, molecular computation, arti?cial life, swarm intelligence, ants colony, arti?cial immune systems, etc. , with innovative applications to knowledge d- covery, ?nance, operations research, and more.
Fuzzy systems and knowledge discovery ; Vol. 3613 ; 2nd International Conference, FSKD 2005, Changsha, China, August 27-29, 2005, Proceedings, Part I
This book and its sister volume, LNAI 3613 and 3614, constitute the proce- ings of the Second International Conference on Fuzzy Systems and Knowledge Discovery (FSKD 2005), jointly held with the First International Conference on Natural Computation (ICNC 2005, LNCS 3610, 3611, and 3612) from - gust 27–29, 2005 in Changsha, Hunan, China. FSKD 2005 successfully attracted 1249 submissions from 32 countries/regions (the joint ICNC-FSKD 2005 received 3136 submissions). After rigorous reviews, 333 high-quality papers, i. e. , 206 long papers and 127 short papers, were included in the FSKD 2005 proceedings, r- resenting an acceptance rate of 26. 7%. The ICNC-FSKD 2005 conference featured the most up-to-date research - sults in computational algorithms inspired from nature, including biological, e- logical, and physical systems. It is an exciting and emerging interdisciplinary area in which a wide range of techniques and methods are being studied for dealing with large, complex, and dynamic problems. The joint conferences also promoted cross-fertilization over these exciting and yet closely-related areas, which had a signi?cant impact on the advancement of these important technologies. Speci?c areas included computation with words, fuzzy computation, granular com- tation, neural computation, quantum computation, evolutionary computation, DNA computation, chemical computation, information processing in cells and tissues, molecular computation, arti?cial life, swarm intelligence, ants colony, arti?cial immune systems, etc. , with innovative applications to knowledge d- covery, ?nance, operations research, and more.
Fuzzy sets and their extensions : Representation, aggregation and models : Intelligent systems from decision making to data mining, web intelligence and computer vision
This book presents an up-to-date state of current research in the use of fuzzy sets and their extensions, paying attention to foundation issues and to their application to four important areas where fuzzy sets are seen to be an important tool for modelling and solving problems.
Fuzzy portfolio optimization : Theory and methods
This is the first monograph on fuzzy portfolio optimization. By using fuzzy mathematical approaches, quantitative analysis, qualitative analysis, the experts' knowledge and the investors' subjective opinions can be better integrated into portfolio selection models. The contents of this book mainly comprise of the authors' research results for fuzzy portfolio selection problems in recent years. In addition, in the book, the authors introduce some other important progress in the field of fuzzy portfolio optimization. Some fundamental issues and problems of portfolio selection have been studied systematically and extensively by the authors to apply fuzzy systems theory and optimization methods. A new framework for investment analysis is presented in this book. A series of portfolio selection models are given and some of them are more efficient for practical applications. Some application examples are given to illustrate those models.
Fuzzy Logic : A Spectrum of Theoretical & Practical Issues
This book exclusively surveys the active on-going research of the current maturity of fuzzy logic over the last four decades. Many world leaders of fuzzy logic have enthusiastically contributed their best research results into five theoretical, philosophical and fundamental sub areas and nine distinctive applications, including two PhD dissertations from two world class universities dealing with cutting-edge research areas of bioinformatics and geological science. Beyond the scope of survey and collection of the book, one important spin off is the emerging and recognition of a major scientific paradigm shift from the conventional mathematics to the mathematics of uncertainty, which arguably holds the key to solving very difficult and complex problems in biological and social sciences alike. The book, loaded with historical perspective, creative thinking, critical reviewing, and uniquely constructed strategy for future growth of this dynamic research area, is an invaluable resource for active researchers at all levels, university administrators, foundation directors, funding agency program chiefs, research & development planners and technological assessors.
Fuzzy Implications
Fuzzy Implications (FIs) generalize the classical implication and play a similar important role in Fuzzy Logic (FL), both in FL_n and FL_w in the sense of Zadeh. Their importance in applications of FL, viz., Approximate Reasoning (AR), Decision Support Systems, Fuzzy Control (FC), etc., is hard to exaggerate. This treatise is perhaps the first attempt at dealing exclusively with this class of operations.
Fuzzy Group Theory
This book presents an up-to-date account of research in important topics of fuzzy group theory. The book concentrates on the theoretical aspects of fuzzy subgroups of a group. It also includes applications to some abstract recognition problems and to coding theory. The book begins with basic properties of fuzzy subgroups. The notions of ascending series and descending series of fuzzy subgroups are used to define nilpotency of a fuzzy subgroup. The material presented in this book makes it a good reference for graduate students and researchers working in fuzzy group theory.
