الصفحة 26
الصفحة 26
Basic principles of drug discovery and development ; 2nd ed.
Presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields. Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics. Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborator’s fields.
Bacterial signal transduction : Networks and drug targets
Interactions among different TCSs enable one system to respond to multiple signals, which is important for bacteria to minutely adjust themselves to complex environmental changes. Such interactions are found or predicted in various bacteria in this book. Over the past decade, a vast amount of exciting new information on the signal transduction pathway in bacteria has been brought to light. Reports on these develop› ments have been put together in this book, Bacterial Signal Transduction: Networks andDrug Targets. This book Offers an incentive for graduate students, academic scientists, and researchers in the pharmaceutical industry to further elucidate the TCS networks and apply them in the search for novel drugs.
Autonomy oriented computing : From problem solving to complex systems modeling
Autonomy Oriented Computing explores the important theoretical and practical issues in AOC, by analyzing methodologies and presenting experimental case studies. The book serves as a comprehensive reference source for researchers, scientists, engineers, and professionals in all fields concerned with this promising new development in computer science. It can also be used as a main or supplementary text in graduate and undergraduate programs across a broad range of computer-related disciplines, including Robotics and Automation, Amorphous Computing, Image Processing and Computer Vision, Programming Paradigms, Computational Biology, and many others. The first part of the book, Fundamentals, describes the basic concepts and characteristics of an AOC system, and then it enumerates the critical design and engineering issues faced in AOC system development. The second part of the book, AOC in Depth, provides a detailed analysis of methodologies and case studies to evaluate the use of AOC in problem solving and complex system modeling. The final chapter reviews the essential features of the AOC paradigm and outlines a number of possibilities for future research and development.
Autonomous vehicles technological trends
The automotive industry has always been synonymous with research and innovation, but nowadays the industry is adding pressure and is establishing the agenda of the researchers from the field. Visions have been provided, and the hardware and the software exist; the only question remaining is: “who is going to deliver”? To answer this question, we encouraged scientists, researchers, industry specialists, and academics to share their vision of autonomous vehicles. What will the platform look like? What kind of hardware and software is most suitable? Who will make the connection between these two interdependent environments (and how), so that in the end the AI will define the process? These are the pressing issues of the current moment, and this Special Issue will help all those interested in the topic to promote their vision and ideas.
Autonomous Robots and Agents
This book deals with the theoretical and methodological aspects of incorporating intelligence in Autonomous Robots and Agents. Challenges faced in the real world to accomplish complex tasks, which require collaborative efforts, and methods to overcome them, are detailed. Several informative articles deal with navigation, localization and mapping of mobile robots, a problem that engineers and researchers are grappling with all the time.This edited volume is targeted to present the latest state-of-the-art methodologies in Robotics. It is a compilation of the extended versions of the very best papers selected from the many that were presented at the 3rd International Conference on Autonomous Robots and Agents (ICARA 2006) which was held at Palmerston North, New Zealand from 11-14 December, 2006. Scientists and engineers who work with mobile robots will find this book very useful and stimulating.
Automatic Quantum Computer Programming : A Genetic Programming Approach
Computer science will be radically transformed if ongoing efforts to build large-scale quantum computers eventually succeed and if the properties of these computers meet optimistic expectations. Nevertheless, computer scientists still lack a thorough understanding of the power of quantum computing, and it is not always clear how best to utilize the power that it is understood. This dilemma exists because quantum algorithms are difficult to grasp and even more difficult to write. Despite large-scale international efforts, only a few important quantum algorithms are documented, leaving many essential questions about the potential of quantum algorithms unanswered.
Automatic Differentiation : Applications, Theory, and Implementations
This collection covers the state of the art in automatic differentiation theory and practice. Practitioners and students will learn about advances in automatic differentiation techniques and strategies for the implementation of robust and powerful tools. Computational scientists and engineers will benefit from the discussion of applications, which provide insight into effective strategies for using automatic differentiation for design optimization, sensitivity analysis, and uncertainty quantification.
Autoimmune Diseases of the Skin : Pathogenesis, Diagnosis, Management
The book provides an overview and the latest information on the broad spectrum of cutaneous autoimmune disorders for clinicians, scientists and practitioners in dermatology, medicine, rheumatology, ENT, pediatrics and ophthalmology. The book is unique since it presents the state-of-the-art knowledge on pathophysiology, clinical diagnosis and management of these disorders provided by the world experts in the field. The primary intention is to broaden the understanding of the pathophysiology of cutaneous autoimmune disorders and to provide a practical guide to how to identify and handle these conditions. The book is illustrated with many tables, illustrative figures and clinical color photographs. The second edition has been extended by chapters on autoimmune pigmentary disorders (vitiligo), hairloss (alopecia areata) and cutaneous symptoms of rheumatic disorders.
Astrobiology : Future perspectives
Astrobiology, a new exciting interdisciplinary research field, seeks to unravel the origin and evolution of life wherever it might exist in the Universe. The current view of the origin of life on Earth is that it is strongly connected to the origin and evolution of our planet and, indeed, of the Universe as a whole. We are fortunate to be living in an era where centuries of speculation about the two ancient and fundamental problems: the origin of life and its prevalence in the Universe are being replaced by experimental science. The subject of Astrobiology can be approached from many different perspectives. This book is focused on abiogenic organic matter from the viewpoint of astronomy and planetary science and considers its potential relevance to the origins of life on Earth and elsewhere. Guided by the review papers in this book, the concluding chapter aims to identify key questions to motivate future research and stimulate astrobiological applications of current and future research facilities and space missions. Today’s rich array of new spacecraft, telescopes and dedicated scientists promises a steady flow of discoveries and insights that will ultimately lead us to the answers we seek.
Assessment of the fate and effects of toxic agents on water resources
Like all limited and vulnerable resources, water has become one of the potential targets of terrorists. Coastal lagoons are especially vulnerable as they are densely populated centers of commerce and/or tourism. This volume addresses the basic scientific concepts that must be integrated by decisionmakers to minimize damages and optimize recovery operations in the aftermath of such an attack. Scientists from many disciplines including water resource management, hydrodynamics, aquatic ecology and social science combine their expertise in an effort to assess and model emergency scenarios for coastal lagoon systems. This case study uses existing numerical models such as-EFCD, WASP and AQUATOX are used to demonstrate how to optimize rapid response and decision-making
Artificial intelligence techniques for satellite image analysis
The main objective of this book is to provide a common platform for diverse concepts in satellite image processing. In particular it presents the state-of-the-art in Artificial Intelligence (AI) methodologies and shares findings that can be translated into real-time applications to benefit humankind. Interdisciplinary in its scope, the book will be of interest to both newcomers and experienced scientists working in the fields of satellite image processing, geo-engineering, remote sensing and Artificial Intelligence. It can be also used as a supplementary textbook for graduate students in various engineering branches related to image processing.
Artificial intelligence in dentistry
Focuses on various aspects of artificial intelligence in dentistry, assisting dentists, specialists, and scientists in advancing their understanding, knowledge, training, and expertise in this field of artificial intelligence.
Artificial intelligence and simulation ; 13th international conference on AI, simulation, and planning in high autonomy systems, AIS 2004, Jeju Island, Korea, October 4-6, 2004, Revised Selected Papers
This volume is the proceedings of AIS 2004. The AI, Simulation and Planning in High Autonomy Systems (AIS) 2004 C- ference was held on Korea, AIS 2004 was the thirteenth in the series ofbiennial conferences on AI and simulation. The conf- enceprovidedthemajorforumforresearchers ,scientistsandengineerstopresent the state-of-the-art research results in the theory and applications of AI, si- lation and their fusion. This volume includes the invited speakers’ papers, along with thepapers presented in the conference.In addition to the scientific tracks presented.
Artificial intelligence and neural networks ; 14th Turkish Symposium, TAINN 2005, Izmir, Turkey, June 16-17, 2005, Revised Selected Papers
The Turkish Artificial Intelligence and Neural Network Symposium (TAINN) is an annual meeting where scientists present their new ideas and algorithms on artificial intelligence and neural networks with either oral or poster presentation. The TAINN- Turkish Conference on AI and NN Series started in 1992 at Bilkent University in Ankara, envisioned by various researchers in AI and NN then at the Bilkent, Middle East Technical, Bo aziçi and Ege universities as a forum for local researchers to get together and communicate. Since then, TAINN has been held annually around early summer. This year the 14th TAINN conference was organized by the EE and CE departments of the zmir Institute of Technology with an emphasis on international contributions.
Artificial intelligence and knowledge engineering applications : A bioinspired approach ; 1st international work-Conference on the interplay between natural and artificial computation, IWINAC 2005, Las Palmas, Canary Islands, Spain, June 15-18, 2005, Proceedings, Part II
The computational paradigm considered here is a conceptual, theoretical andformal framework situated above machines and living creatures (two instantia-tions), sufficiently solid, and still non-exclusive, that allows us:1. to help neuroscientists to formulate intentions, questions, experiments, meth-ods and explanation mechanisms assuming that neural circuits are the psy-chological support of calculus;2. to help scientists and engineers from the fields of artificial intelligence (AI)and knowledge engineering (KE) to model, formalize and program the com-putable part of human knowledge;3. to establish an interaction framework between natural system computation(NSC) and artificial system computation (ASC) in both directions, fromASC to NSC (in computational neuroscience), and from NSC to ASC (inbioinspired computation).
Artificial intelligence and data mining approaches in security frameworks
Offers solutions to the problems of security, outlining the concepts behind allowing computers to learn from experience and understand the world in terms of a hierarchy of concepts, with each concept defined through its relation to simpler concepts. provides state of the art approaches of artificial intelligence and data mining in these areas. It includes areas of detection, prediction, as well as future framework identification, development, building service systems and analytical aspects. In all these topics, applications of AI and data mining, such as artificial neural networks, fuzzy logic, genetic algorithm and hybrid mechanisms, are explained and explored. This book is aimed at the modeling and performance prediction of efficient security framework systems, bringing to light a new dimension in the theory and practice. This groundbreaking new volume presents these topics and trends, bridging the research gap on AI and data mining to enable wide-scale implementation. Whether for the veteran engineer or the student, this is a must-have for any library. This groundbreaking new volume: Clarifies the understanding of certain key mechanisms of technology helpful in the use of artificial intelligence and data mining in security frameworks ; Covers practical approaches to the problems engineers face in working in this field, focusing on the applications used every day ; Contains numerous examples, offering critical solutions to engineers and scientists ; Presents these new applications of AI and data mining that are of prime importance to human civilization as a whole
Artificial Intelligence : Applications and innovations
It's about the science of artificial intelligence (AI). AI is the study of the design of intelligent computational agents. This book provides a valuable resource for researchers, scientists, professionals, academicians and students dealing with the new challenges and advances in the areas of AI and innovations. This book also covers a wide range of applications of machine learning such as fire detection, structural health and pollution monitoring and control. Provides insight into prospective research and application areas related to industry and technology / Discusses industry- based inputs on success stories of technology adoption / Discusses technology applications from a research perspective in the field of AI / Provides a hands- on approach and case studies for readers of the book to practice and assimilate learning
Artificial immune systems ; Vol. 4163 : 5th International conference, ICARIS 2006, Oeiras, Portugal, September 4-6, 2006, Proceedings
ICARIS 2006 is the ?fth instance of a series of conferences dedicated to the comprehension and the exploitation of immunological principles through their translation into computational terms.Their axis of research tries to stabilize an on-going identity somewhere in the crossroad of engineering (building useful artifacts), natural sciences (biologyor psychology— improving the comprehension and prediction of natural phenomena) and t- oretical computer sciences (developing and mastering the algorithmic world). Accordingly and depending on which of these perspectives receives more s- port, they attempt at attracting di?erent kinds of scientists and at stimul- ing di?erent kinds of scienti?c attitudes. For many years and in the previous ICARIS conferences, it was clearly the “engineering.
Artificial gravity
"This book reviews the principle and rationale for using artificial gravity during space missions, and describes the current options proposed, including a short-radius centrifuge contained within a spacecraft. In Artificial Gravity, experts provide recommendations on the research needed to assess whether or not short-radius centrifuge workouts can help limit deconditioning of physiological systems.""Aided by an exquisite group of experts, Gilles Clement and Angie Bukley have managed to put together THE new, comprehensive reference book on artificial gravity. This book will be an essential resource for students, scientists, and program planners alike."
Arterial Grafting for Coronary Artery Bypass Surgery
The second edition of this book provides updated knowledge about the biological characteristics and clinical use of arterial grafts for coronary artery bypass surgery. The reader will find first-hand information on arterial grafts as well as vein grafts with regard to biological characteristics, clinical use including off-pump coronary bypass grafting surgery, results, and future developments. Written by world-renowned cardiac surgeons and cardiovascular research scientists working in this area.
