الصفحة 25
الصفحة 25
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Chromosomal alterations : Methods, results and importance in human health

Cytogenetics is a very important research tool in basic and applied research. The uses of cytogenetics in human-population monitoring, in biological dosimetry in radiation accidents and in astronauts and as a predictive measure of cancer are topics discussed in this book. The book will help the reader to better understand cytogenetics and the intricacies of the methodology. The different methods of fluorescence in situ hybridization are discussed and the results achieved are presented. The book provides a comprehensive review of basic and applied aspects of cytogenetics and therefore will be of interest to all who are interested in chromosomes and their alterations by different types of mutagens, including chemical mutagens and ionizing and nonionizing radiation, with special reference to electromagnetic fields.

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Character Evidence : An Abductive Theory

This book is on evidence for character judgments, This book answers the question using a model of abductive reasoning, commonly called inference to the best explanation. The methodology of the book derives from recent work on models of reasoning in argumentation theory and artificial intelligence. The aim is not just to show how character judgments are made, but to show how they should be properly be made based on sound reasoning, in order to avoid errors and superficial judgments of a kind that are common.

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Chance Discoveries in Real World Decision Making : Data-based Interaction of Human intelligence and Artificial Intelligence

For this book, the editors invited and called for contributions from indispensable research areas relevant to "chance discovery," which has been defined as the discovery of events significant for making a decision, and studied since 2000. From respective research areas as artificial intelligence, mathematics, cognitive science, medical science, risk management, methodologies for design and communication, the invited and selected authors in this book present their particular approaches to chance discovery. The chapters here show contributions to identifying rare or hidden events and explaining their significance, predicting future trends, communications for scenario development in marketing and design, identification effects and side-effects of medicines, etc.

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CFN Lectures on Functional Nanostructures : Vol.1

This book contains a selection of lectures from the first Summer School organized by the Center for Functional Nanostructures (CFN) at the University of Karlsruhe. The mission of the CFN is to carry out research in the following areas: nanophotonics, nanoelectronics, molecular nanostructures and nanostructured materials. The aim of the summer schools is mainly to exchange new ideas and illustrate emerging research methodologies through a series of lectures. This is reflected by both the selection of topics addressed in the present volume as well as the tutorial aspect of the contributions.

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Certification and security in inter-organizational E-services ; IFIP 18th World Computer Congress, August 22-27, 2004, Toulouse, France

This collection of papers offers real-life application experiences, research results and methodological proposals of direct interest to systems experts and users in governmental, industrial and academic communities. This book also documents several important developments. The uptake of distributed computational infrastructure oriented to service provision, like Web-Services and Grid, is making C&S even more important. E-services based on legacy systems managed by autonomous and independent organizations, a common situation in the public administration sector, increase overall complexity. The increased presence and use of e-service IT-infrastructures depends on the critical ability required for all security issues, from the basic (availability, authentication, integrity, confidentiality) to the more complex (e.g. authorization, non-repudiation).

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Cellular Genetic Algorithms

CELLULAR GENETIC ALGORITHMS defines a new class of optimization algorithms based on the concepts of structured populations and Genetic Algorithms (GAs). The authors explain and demonstrate the validity of these cellular genetic algorithms throughout the book. This class of genetic algorithms is shown to produce impressive results on a whole range of domains, including complex problems that are epistatic, multi-modal, deceptive, discrete, continuous, multi-objective, and random in nature. The focus of this book is twofold. On the one hand, the authors present new algorithmic models and extensions to the basic class of Cellular GAs in order to tackle complex problems more efficiently. On the other hand, practical real world tasks are successfully faced by applying Cellular GA methodologies to produce workable solutions of real-world applications.

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Catalytic role of amino acids in organic reactions

Asymmetric organometallic and organocatalytic processes have attracted great interest. Asymmetric synthesis using both natural and unnatural amino acids has been tremendously important from synthetic as well as industrial viewpoints, and numerous new methodologies have been developed in the last decades. Herein we provide an overview of old and very recent (since 1900 till now) advances and applications in the area of heterogeneous catalysis, homogeneous catalysis, electrocatalysis, photocatalysis, organocatalysis, thermal catalysis using amino acids [proline, glycine, alanine, valine, serine, threonine, cysteine, methionine, asparagine, glutamine, lysine, arginine, histidine, aspartate, glutamate, phenylalanine, and tryptophan], (supported or unsupported), an amino acid containing materials or amino acids derivatives as an essential component of catalysts, this book highlights the most important and recent developments to immobilize or support amino acids on various support materials. This book is suitable as supplementary reading for courses targeting the design, synthesis, and application of chiral catalysts, asymmetric catalysis, and sustainable production.

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Case-Based Approximate Reasoning

Case-based reasoning (CBR) has received a great deal of attention in recent years and has established itself as a core methodology in the field of artificial intelligence. The key idea of CBR is to tackle new problems by referring to similar problems that have already been solved in the past. More precisely, CBR proceeds from individual experiences in the form of cases. The generalization beyond these experiences typically relies on a kind of regularity assumption demanding that 'similar problems have similar solutions'. Making use of different frameworks of approximate reasoning and reasoning under uncertainty, notably probabilistic and fuzzy set-based techniques, this book develops formal models of the above inference principle, which is fundamental to CBR. The case-based approximate reasoning methods thus obtained especially emphasize the heuristic nature of case-based inference and aspects of uncertainty in CBR. This way, the book contributes to a solid foundation of CBR which is grounded on formal concepts and techniques from the aforementioned fields. Besides, it establishes interesting relationships between CBR and approximate reasoning, which not only cast new light on existing methods but also enhance the development of novel approaches and hybrid systems.

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Case Studies in Ethics and HIV Research

Studies from the United States and abroad depict the ongoing balance of risks and benefits while analyzing issues that range from confidentiality and informed consent to conducting studies with minority and other marginalized populations, from dealing with government and other funding agencies to ownership of findings. The chapter topics and case studies are apt, and the analyses throughout are thought-provoking.

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Care-Related Quality of Life in Old Age : Concepts, Models and Empirical Findings

Care-Related Quality of Life in Old Age explains the theory behind Care Keys, its methodology, empirical findings, and practical considerations in promoting effective, efficient elder care aimed at social and emotional well-being and including disabled and cognitively impaired patients.

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Cardiac Safety of Noncardiac Drugs : Practical Guidelines for Clinical Research and Drug Development

The authors explain the parameters of cardiac safety at all stages of clinical research and drug development, including both the preclinical and pharmacogenomic aspects generally and the clinical methodologies and technical aspects for investigational drugs based on cardiac repolarization, as defined by the duration of the QTc interval. Additional chapters comprehensively review the application of electrocardiology in clinical research

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Car deal : The ultimate used-cars marketplace

This is an effort to represents the design and implementation of a mobile application that serves as a marketplace for buying and selling used cars. The application is developed using Flutter, a popular cross-platform framework, and integrates an Artificial Intelligence (AI) model to predict the price of used cars based on various parameters, such as the car's model, age, mileage, and condition. The report provides a comprehensive overview of the project's development process, including the use of agile methodology and various technologies, such as Firebase, Python, and TensorFlow. The AI model's accuracy is evaluated using statistical metrics, such as Mean Absolute Error (MAE) and Root Mean Squared Error (RMSE).

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Cancer Informatics in the Post Genomic Era : Toward Information-Based Medicine

Medical information science requires analytic tools. This is achieved by developing and assessing methods and systems for the acquisition, processing, and interpretation of patient data, aided by scientific discovery. Cancer Informatics in Post-Genomic Era provides both the necessary methodology and practical information tools.Key challenges include integrating research and clinical care, sharing data, and establishing partnerships within and across sectors of patient diagnosis and treatment.Addressing important clinical questions in cancer research will benefit from expanding computational biology.

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Cancer Chemoprevention ; Vol.2 : Strategies for Cancer Chemoprevention

In Cancer Chemoprevention, Volume 2: Strategies for Cancer Chemoprevention, leading chemopreventives investigators comprehensively describe the exciting methodologies that are accelerating progress in the chemoprevention field and review the state of clinical development of preventive agents in the major human cancer target organs. The authors provide sound guidelines for cancer chemopreventive drug development, detailing general strategies and methods for drug discovery, preclinical efficacy, characterization of precancers, safety evaluation of clinical cohorts, and clinical trial design.

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Canadian Semantic Web

This book covers a variety of well known topics of interest to practitioners in industry and research scientists. The range of topics includes languages, tools and methodologies for the semantic Web, semantic Web-based ontology management and engineering, semantic Web services, practical applications of the semantic Web techniques, artificial intelligence methods and tools for the semantic Web, software agents on the semantic Web, visualization and modeling of the semantic Web. The goal of this book is to provide a state-of-the-art review of the research as well as to introduce topics of interest to experts.

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CADD and informatics in drug discovery

Updates knowledge on recent advances in computational and bioinformatics tools/techniques and their practical applications in modern drug design and discovery programme. Also it encompasses fundamental principles, advanced methodologies and applications of various CADD approaches including several cutting-edge areas / presenting recent developments covering ongoing trends in the field of computer-aided drug discovery. Having contributions by a global team of experts, the book is expected to be an ideal resource for drug discovery scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, biologists, RandD personnel, researchers, students, teachers and those working in the field of drug discovery. It will fill the knowledge gaps that exist in the current CADD approaches and methodologies/ protocols being widely used in both academic and research practices. Further, a special focus on current status of various computational drug design approaches (SBDD, LBDD, De-novo drug design, Pharmacophore-based search), bioinformatics tools and databases, computational screening and modeling of phytochemicals/natural products, artificial intelligence and machine learning, and network pharmacology and system biology would certainly guide researchers, students or readers to conduct their research in the emerging area(s) of interest. It is also expected to be highly beneficial to different stakeholders working in the pharmaceutical and biotechnology industries (RandD), the academic as well as research sectors. .

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By-catch Reduction in the Worlds Fisheries

This book comes after several decades of outstanding and successful research that has helped ameliorate some of the most important and controversial fisheries issues in the world – those associated with the unwanted wastage of fish from by-catch and discarding. The 8 chapters encompass contributions from 27 of the world’s leading experts in by-catch reduction. They take the reader through most aspects of the field at a variety of scales and viewpoints. They examine the methodologies used to develop by-catch reduction techniques and provide new avenues for assisting and broadening such work. Case studies are provided that encompass most of the world’s fishing techniques and regions.

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Business Models and Corporate Reporting : Defining the Platform to Illustrate Value Creation

This book discusses the role of business models in corporate reporting. It illustrates the evolution of non-financial reporting, the importance of business model reporting, and the main conceptualisations of business models. It also offers a methodological contribution to the assessment of business model reporting. Finally, it discusses the main implication of business model reporting for different categories of subjects and some challenges related to this kind of disclosure

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Building construction and technology

Highlights various aspects of building construction industry based on data from field studies. It discusses the challenges, methodologies, technological applications in building construction, technology, and management. The book presents new approaches to effective building construction and an understanding of the impact of applications of latest technologies.

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Building construction : From principle to detail ; Vol.1 : Fundamentals

Construction is the means by which designing architects and engineers transform a design idea into built reality. It is from this perspective that the subject of 'building construction design' is dealt with by the architect José Luis Moro in three comprehensive volumes. Each is dedicated to the methodological, physical and functional fundamentals, the conception of a constructional solution, and finally its implementation in the constructional detail. Not only do the three volumes provide extensive content; they also ensure the greatest possible clarity in the text and graphics, in order to make it easier for learners to access the material. Importantly, they focus not only on conveying technical and scientific information, but also on demonstrating the complex relationships and interactions between design, material and construction.

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