الصفحة 24
الصفحة 24
Bioinformatics and systems biology : Collaborative research and resources
Collaborative research in bioinformatics and systems biology is a key element of modern biology and health research. This book highlights and provides access to many of the methods, environments, results and resources involved, including integral laboratory data generation and experimentation and clinical activities. Collaborative projects embody a research paradigm that connects many of the top scientists, institutions, their resources and research worldwide, resulting in first-class contributions to bioinformatics and systems biology. Central themes include describing processes and results in collaborative research projects using computational biology and providing a guide for researchers to access them. The book is also a practical guide on how science is managed. It shows how collaborative researchers are putting results together in a way accessible to the entire biomedical community.
Bioinformatics and Computational Biology Solutions Using R and Bioconductor
Bioconductor is a widely used open source and open development software project for the analysis and comprehension of data arising from high-throughput experimentation in genomics and molecular biology. Bioconductor is rooted in the open source statistical computing environment R. This volume's coverage is broad and ranges across most of the key capabilities of the Bioconductor project, including: Importation and preprocessing of high-throughput data from microarray, proteomic, and flow cytometry platforms / Curation and delivery of biological metadata for use in statistical modeling and interpretation. / Statistical analysis of high-throughput data, including machine learning and visualization,modeling and visualization of graphs and networks. This book is a dynamic document. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.
Biochemical Mechanisms of Detoxification in Higher Plants : Basis of Phytoremediation
Plants play a key role in purifying the biosphere of the toxic effects of industrial activity. This book shows how systematic application of the results of investigations into the metabolism of xenobiotics (foreign, often toxic substances) in plants could make a vastly increased contribution to planetary well-being. Deep physiological knowledge gained from an accumulation of experimental data enables the great differences between the detoxifying abilities of different plants for compounds of different chemical nature to be optimally exploited. Hence planting could be far more systematically adapted to actual environmental needs than is actually the case at present.
Bioanalytics : Analytical methods and concepts in biochemistry and molecular biology
Analytical methods are the essential enabling tools of the modern biosciences. This book presents a comprehensive introduction into these analytical methods, including their physical and chemical backgrounds, as well as a discussion of the strengths and weakness of each method. It covers all major techniques for the determination and experimental analysis of biological macromolecules, including proteins, carbohydrates, lipids and nucleic acids.
Bioactive Confirmation II
Specific binding of a ligand to a receptor is a key step in a variety of biol- ical processes, such as immune reactions, enzyme cascades, or intracellular transport processes. The ligand-receptor terminology implies that the rec- tor molecule is signi?cantly larger than the ligand, and the term "bioactive conformation" usually characterizes the conformation of a ligand when it is bound to a receptor. In a more general sense, bioactive conformation applies toanymoleculeinabiologicallyrelevantboundstateregardlessofsizecons- erations. Mostofthecontributions tothisbookaddressligandsthat aremuch smaller than their receptors. X-ray crystallography and high resolution NMR spectroscopy are the two main experimental techniques used to study bioactive conformations. The- fore, the twovolumes ofthisbookcover approachesthat use either ofthetwo techniques, or a combination thereof.
Big Data Recommender Systems ; Vol.2 : Application Paradigms
Combines experimental and theoretical research on big data recommender systems to help computer scientists develop new concepts and methodologies for complex applications. It includes original scientific contributions in the form of theoretical foundations, comparative analysis, surveys, case studies, techniques and tools. First designed to generate personalized recommendations to users in the 90s, recommender systems apply knowledge discovery techniques to users’ data to suggest information, products, and services that best match their preferences. In recent decades, we have seen an exponential increase in the volumes of data, which has introduced many new challenges. recommender systems. Volume 2 covers a broad range of application paradigms for recommender systems over 22 chapters
Big Data Recommender Systems ; Vol.1 : Algorithms, Architectures, Big Data, Security and Trust
Combines experimental and theoretical research on big data recommender systems to help computer scientists develop new concepts and methodologies for complex applications. It includes original scientific contributions in the form of theoretical foundations, comparative analysis, surveys, case studies, techniques and tools.
Bifurcations, Instabilities, Degradation in Geomechanics
Leading international researchers and practitioners of bifurcations and instabilities in geomechanics debate the developments and applications which have occurred over the last few decades. The topics covered include modeling of bifurcation, structural failure of geomaterials and geostructures, advanced analytical, numerical and experimental techniques, and application and development of generalised continuum models etc. In addition analytical solutions, numerical methods, experimental techniques, and case histories are presented. Beside fundamental research findings, applications in geotechnical, petroleum, mining, and bulk materials engineering are emphasised.
Bidding Strategies in Agent-Based Continuous Double Auctions
Presents a new bidding strategy for agents to adopt in CDAs and propose tools to enhance the performance of existing bidding strategies in CDAs. The superior performance of the new bidding strategy as well as the tools presented in this book are illustrated through extensive experiments.
Beyond Safety Training : Embedding Safety in Professional Skills
Investigates why, despite more and more resources devoted to safety training, expectations are not entirely met, particularly in the industrial sectors that have already achieved a high safety level. It not only reflects the most precious viewpoints of experts from different disciplines, different countries, with experiences in various industrial fields at the cutting edge of theories and practices in terms of safety, professionalization and their relationships. It also consolidates the positioning of the Foundation for an Industrial Safety Culture, highlighting what is currently considered at stake in terms of safety training, taking into account the system of constraints the different stakeholders are submitted to. It reports some success stories as well as elements which could explain the observed plateau in terms of outcome. It identifies some levers for evolution for at-risk industry and outlines a possible research agenda to go further with experimental solutions.
Best of detail : Holz / wood
Brings together highlights from DETAIL about wood as a material. Besides a theoretical basis, the publication also offers a comprehensive section on projects, ranging from experiments to elaborate details, which provides abundant inspiration and examples of successful architectural design using wood.
Behaviour and design of steel and composite connections in fire
The only dedicated book on fire performance of connections in steel and composite structures. Recent experimental and numerical studies indicate that connections are among the most vulnerable and critical parts of these structures. This book synthesises these research findings and explains the essential features in one single source.
Beginning Excel What-If Data Analysis tools : Getting started with goal seek, data tables, scenarios, and solver
Excels what-if data analysis tools let you experiment with your data to project future results. In turn, these predictions will lead to better decision making and unlock the mystery of many business analysis scenarios. For example, what-if data analysis tools will enable you to forecast how lowering the price per unitwhile increasing projected unit salesmight affect your profit margins. Beginning Excel What-If Data Analysis Tools explores the use of Goal Seek, Data Tables, Scenarios, and Solver to help you get insight on your data. This book is focused and to the point, and it provides tutorial treatment of what-if tools in a practical, hands-on manner.
Basic knowledge of pharmacology
Concise and up-to-date coverage of the most important drugs Integration of experimental and clinical pharmacology with focus on diseases Discusses the most important drugs (400) in the context of relevant diseases. Summary tables and schemes, MCQ exam questions, case studies and a list of drugs aid memorization of the material before an exam. All chapters are written in the same concise style and use a modern and precise pharmacological nomenclature. After reading of the book, the student will be able to critically assess the proper use of the most important drugs and advise patients properly. The didactic concept of the book has been developed on the author’s own pharmacology courses for which he has received numerous teaching awards. The book takes advantage of the learning spiral, in which material is presented repeatedly from various angles.
Bacteriophage therapy: From lab to clinical practice
Details new and updated experimental approaches for isolating, formulating, and engineering bacteriophage medicinal products. Authored by leading experts and written in the highly successful Methods in Molecular Biology series format, each chapter includes introductions to their respective topics, lists of the necessary materials and reagents, step-by-step reproducible laboratory protocols, and valuable tips for troubleshooting and avoiding known pitfalls.
Bacterial chromatin : Methods and protocols
Brings together new and updated methods to explore the structure and function of bacterial chromatin from molecular to the cellular scale. Chapters detail experimental protocols of in vivo and in vitro approaches, approaches to genome structure modeling, and data analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Axions : Theory, Cosmology, and Experimental Searches
Axions are peculiar hypothetical particles that could both solve the CP problem of quantum chromodynamics and at the same time account for the dark matter of the universe. Based on a series of lectures by world experts in this field held at CERN (Geneva), this volume provides a pedagogical introduction to the theory, cosmology and astrophysics of these fascinating particles and gives an up-to-date account of the status and prospect of ongoing and planned experimental searches. Learners and practitioners of astroparticle physics will find in this book both a concise introduction and a current reference work to a showcase topic that connects the "inner space" of the elementary particle world with the "outer space" of the universe at large.
Autonomy oriented computing : From problem solving to complex systems modeling
Autonomy Oriented Computing explores the important theoretical and practical issues in AOC, by analyzing methodologies and presenting experimental case studies. The book serves as a comprehensive reference source for researchers, scientists, engineers, and professionals in all fields concerned with this promising new development in computer science. It can also be used as a main or supplementary text in graduate and undergraduate programs across a broad range of computer-related disciplines, including Robotics and Automation, Amorphous Computing, Image Processing and Computer Vision, Programming Paradigms, Computational Biology, and many others. The first part of the book, Fundamentals, describes the basic concepts and characteristics of an AOC system, and then it enumerates the critical design and engineering issues faced in AOC system development. The second part of the book, AOC in Depth, provides a detailed analysis of methodologies and case studies to evaluate the use of AOC in problem solving and complex system modeling. The final chapter reviews the essential features of the AOC paradigm and outlines a number of possibilities for future research and development.
Automated nanohandling by microrobots
Automated Nanohandling by Microrobots introduces an actuation principle for such microrobots and presents a new robot design. Different aspects of this research field regarding the hardware and software implementation of the system components, including the sensory feedback for automated nanohandling, are discussed in detail. Extensive applications of the microrobot station for nanohandling, nano-characterization and nanostructuring are provided, together with the experimental results.
Autoimmunity : Methods and protocols
Brings together a comprehensive and up-to-date collection of protocols that reflect the diverse experimental strategies. Chapters detail T-cell, macrophage characterization, neutrophil functional assays, organoid culture methods, spatial transcriptomics, RNA FISH, microRNA profiling, and ribosome profiling. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
