الصفحة 24
الصفحة 24
Data Monitoring in Clinical Trials : A Case Studies Approach
Randomized clinical trials are the gold standard for establishing many clinical practice guidelines and are central to evidence based medicine. Obtaining the best evidence through clinical trials must be done within the boundaries of rigorous science and ethical principles. One fundamental principle is that trials should not continue longer than necessary to reach their objectives. Therefore, trials must be monitored for recruitment progress, quality of data, adherence to patient care or prevention standards, and early evidence of benefit or harm. Frequently, a group of external experts, independent from the investigators and trial sponsor, is charged with this monitoring responsibility, especially for safety and early benefit. This group is referred to by various names, such as a data monitoring committee or a data and safety monitoring board. This book, through a series of case studies presented by many distinguished clinical trial experts, illustrates the complexity of this monitoring process.No other text has as extensive a collection of cases which provide insight into the many issues, often conflicting, that must be examined before recommendations to continue or discontinue a trial can be made. While depth in statistical methods is not required, some familiarity with statistical design and analysis issues in clinical trials is helpful. The cases cover trials which were terminated early for convincing evidence of benefit, or for harmful effects. Cases with complex issues are also included. This series of cases should provide broad background information for potential monitoring committee members and better prepare them for the challenges that may exist in the trials for which they are responsible.
Data mining and Knowledge discovery handbook
Data Mining and Knowledge Discovery Handbook organizes all major concepts, theories, methodologies, trends, challenges and applications of data mining (DM) and knowledge discovery in databases (KDD) into a coherent and unified repository. This book first surveys, then provides comprehensive yet concise algorithmic descriptions of methods, including classic methods plus the extensions and novel methods developed recently. This volume concludes with in-depth descriptions of data mining applications in various interdisciplinary industries including finance, marketing, medicine, biology, engineering, telecommunications, software, and security.
Data Management. Data, Data Everywhere ; 24th British National Conference on Databases, BNCOD 24, Glasgow, UK, July 3-5, 2007, Proceedings
One of the most pressing challenges is to ?nd ways of evolving database technology to cope with its new role in underpinning the massively distributed and heterogeneous applications built on top of the Internet. This has afiected both the ways in which data has been accessed and the ways in which it is represented, with XML data management becoming an important issue and, as such, heavily represented at this conference. It has also brought back issues of performance that might have been considered largely solved by the improvements in hardware, since data now has to be managed on devices of low power and small memory as well as on standard client and powerful server machines. We therefore invited papers on all aspects of data management, particularly related to how dataisused in the ubiquitous environment of the modern Internet by complex distributed and scientific applications.
Data management in a connected world : Essays dedicated to Hartmut Wedekind on the occasion of his 70th birthday
Data management systems play the most crucial role in building large application s- tems. Since modern applications are no longer single monolithic software blocks but highly flexible and configurable collections of cooperative services, the data mana- ment layer also has to adapt to these new requirements. Therefore, within recent years, data management systems have faced a tremendous shift from the central management of individual records in a transactional way to a platform for data integration, fede- tion, search services, and data analysis. This book addresses these new issues in the area of data management from multiple perspectives, in the form of individual contributions, and it outlines future challenges in the context of data management.
Data feminism
We have seen through many examples that data science and artificial intelligence can reinforce structural inequalities like sexism and racism. Data is power, and that power is distributed unequally. This book offers a vision for a feminist data science that can challenge power and work towards justice. This book takes a stand against a world that benefits some (including the authors, two white women) at the expense of others. It seeks to provide concrete steps for data scientists seeking to learn how feminism can help them work towards justice, and for feminists seeking to learn how their own work can carry over to the growing field of data science.
Data and applications security XX ; 20th Annual IFIP WG 11.3 Working Conference on data and applications security, Sophia Antipolis, France, July 31-August 2, 2006, Proceedings
For 20 years, the IFIP WG 11. 3 Working Conference on Data and Appli- tions Security (DBSEC) has been a major forum for presenting originalresearch results, practical experiences, and innovative ideas in data and applications - curity.Like the previous conference, the 20th DBSEC has proved to be up to this challenge. DBSEC 2006 received 56 submissions, out of which the program committee selected22 high-qualitypaperscoveringanumber of diverseresearchtopicssuch as access control, privacy, and identity management.
DARPA Grand Challenge : The Great Robot Race
The goal of the new series of Springer Tracts in Advanced Robotics (STAR) is to bring, in a timely fashion, the latest advances and developments in robotics on the basis of their significance and quality. It is our hope that the wider dissemination of research developments will stimulate more exchanges and collaborations among the research community and contribute to further advancement of this rapidly growing field. The volume edited by Martin Buehler, Karl Iagnemma and Sanjiv Singh presents a unique and extensive collection of the scientific results by the teams which took part into the DARPA Grand Challenge in October 2005 in the Nevada desert. This event reached an incredible peak of popularity in the media, the race of the century like someone called it! The Grand Challenge demonstrated the fast growing progress - ward the development of robotics technology, as it showed the feasibility of using mobile robots operating autonomously in real world scenarios.
Cybersecurity of Digital Service Chains : Challenges, Methodologies, and Tools
This book presents the main scientific results from the H2020 GUARD project. The GUARD project aims at filling the current technological gap between software management paradigms and cybersecurity models, the latter still lacking orchestration and agility to effectively address the dynamicity of the former. This book provides a comprehensive review of the main concepts, architectures, algorithms, and non-technical aspects developed during three years of investigation; the description of the Smart Mobility use case developed at the end of the project gives a practical example of how the GUARD platform and related technologies can be deployed in practical scenarios.
CyberParks – The Interface Between People, Places and Technology: New Approaches and Perspectives
This book is about public open spaces, about people, and about the relationship between them and the role of technology in this relationship. It is about different approaches, methods, empirical studies, and concerns about a phenomenon that is increasingly being in the centre of sciences and strategies – the penetration of digital technologies in the urban space. As the main outcome of the CyberParks Project, this book aims at fostering the understanding about the current and future interactions of the nexus people, public spaces and technology. It addresses a wide range of challenges and multidisciplinary perspectives on emerging phenomena related to the penetration of technology in people’s lifestyles - affecting therefore the whole society, and with this, the production and use of public spaces. Cyberparks coined the term cyberpark to describe the mediated public space, that emerging type of urban spaces where nature and cybertechnologies blend together to generate hybrid experiences and enhance quality of life.
Cybercrime in social media : Theory and solutions
Presents the important components for grasping the potential of social computing with an emphasis on concerns, challenges, and benefits of the social platform in depth. It discusses detection of social-cyber issues, including hate speech, cyberbullying, etc. using deep learning, natural language processing, etc.
Cyber Security and Digital Forensics : Challenges and Future Trends
This groundbreaking new volume, written and edited by a wide range of professionals in this area, covers broad technical and socio-economic perspectives for the utilization of information and communication technologies and the development of practical solutions in cyber security and digital forensics. Not just for the professional working in the field, but also for the student or academic on the university level, this is a must-have for any library.
Cyber Security : Critical Infrastructure Protection
Focus on critical infrastructure protection. The chapters present detailed analysis of the issues and challenges in cyberspace and provide novel solutions in various aspects. The first part of the book focus on digital society, addressing critical infrastructure and different forms of the digitalization, strategic focus on cyber security, legal aspects on cyber security, citizen in digital society, and cyber security training. The second part focus on the critical infrastructure protection in different areas of the critical infrastructure. The chapters cover the cybersecurity situation awareness, aviation and air traffic control, cyber security in smart societies and cities, cyber security in smart buildings, maritime cyber security, cyber security in energy systems, and cyber security in healthcare. The third part presents the impact of new technologies upon cyber capability building as well as new challenges brought about by new technologies. These new technologies are among others are quantum technology, firmware and wireless technologies, malware analysis, virtualization.
Cutting-edge issues in Business Ethics : Continental Challenges to Tradition and Practice
This volume is one of the very few publications dedicated to the challenges that Continental philosophy poses to the field of Business Ethics. The authors want to draw attention to the work of Continental philosophers who have been relegated to the fringes of Business Ethics scholarship, and present some critical perspectives that have been ignored within Business Ethics practice. As such, this volume provides a critique of many of the assumptions that underpin traditional approaches to Business Ethics, and urges its readership to rethink moral agency and epistemology, as well as Business Ethics pedagogy.
Customer Integration in Industrial Innovation Projects
The development of product innovations is permanently challenged by the customers’ rapidly evolving demand for new products and technologies. New approaches for integrating customers into the product innovation process are required and have been exemplified in a software engineering context by Extreme Programming. Patricia Sandmeier demonstrates how a transfer of elements from Extreme Programming to the development practice of industrial products can improve customer integration activities and the innovativeness of the resulting new products. Based on an in-depth case study analysis of two industrial firms and two technical service firms she presents a conceptual model for the integration of customer contributions into the product innovation process. Finally, the author proposes a product innovation process based on discrete product development steps as well as a ‘customer-centered innovation cell’ enabling the development of truly innovative product solutions together with customers.
Current concept in cleft surgery : Moving toward excellence of outcome and reducing the burden of care
Intends to cover cleft-related topics which are mainly focused on the current concept of balancing excellence in outcome and burden of cleft care. The wide spectrum of covered topics includes the understanding challenges and needs to deliver the modern surgical cleft care worldwide and comprehending multidisciplinary-based longitudinal life-changing concept.
Cryptography, information theory, and error-correction : A handbook for the 21st century ; 2nd ed.
A rich examination of the technologies supporting secure digital information transfers from respected leaders in the field. Is an indispensable resource for anyone interested in the secure exchange of financial information. Identity theft, cybercrime, and other security issues have taken center stage as information becomes easier to access. Three disciplines offer solutions to these digital challenges: cryptography, information theory, and error-correction, all of which are addressed in this book. The book also: Shares vital, new research in the field of information theory / Provides quantum cryptography updates / Includes over 350 worked examples and problems for greater understanding of ideas.
Critical Questions in STEM Education
This volume is divided into three sections: the first one describes the nature of the component disciplines of STEM. The next section presents work from leaders representing all STEM disciplines and deals with aspects such as K-12 and post-secondary education. The last section draws conclusions regarding the natures of the disciplines, challenges and advantages of STEM education in terms of theoretical and practical implications. The two final chapters compile arguments from the research chapters, describing themes in research results, and making recommendations for best STEM education practice, and examining areas for future research in STEM education.
Critical Infrastructures at Risk : Securing the European Electric Power System
This book explores the potential risks and vulnerabilities of the European electricity infrastructure, other infrastructures and our society as whole increasingly depend on. The work was initiated by the need to verify the potential effects of the ongoing market and technical transformation of the infrastructure, which is fundamentally changing its operation and performance. The final aim is to set the basis for an appropriate industrial and political European-wide response to the risk challenges.
Critical Information Infrastructures : Resilience and Protection
Starting with some basic definitions and assumptions on the topic, this book explores various aspects of Critical Infrastructures throughout the world – including the technological, political, economic, strategic and defensive. This book will be of interest to the CEO and Academic alike as they grapple with how to prepare Critical Information Infrastructures for new challenges.
Crisis response in higher education : How the pandemic challenged university operations and organisation
This book explores the impact of Covid-19 on universities, and how students, staff, faculty and academic leaders have adapted to and dealt with the impact of the pandemic. Drawing on experiences from Britain, Australia and Sweden, it showcases how Covid has challenged routines and procedures in universities, and thrown them into a disarray of ever-changing events and short-term adaptations. The authors pay particular attention to how students, staff, faculty, and leaders have coped with Covid, through a series of autobiographical portraits of their strains but also heroic efforts in the harshest of circumstances.
