الصفحة 24
الصفحة 24
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Bacterial Fish Pathogens : Disease of Farmed and Wild Fish

This completely revised and updated edition of Bacterial Fish Pathogens is a comprehensive discussion of the biological aspects of the bacterial taxa which cause disease in fish. Since the 3rd edition was published in 1999, much has changed in the control of disease of farmes and wild fish. New pathogens such as Pasteurella skyensis have been described, and antimicrobial compounds for the control of disease have been replaced by alternative methods, such as probiotics. Consideration is given to all the bacterial taxa which have at some time been reported as fish pathogens, whether they are secondary invaders of already damaged tissues or serious, primary pathogens.

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Azaheterocycles Based on -, ß-Unsaturated Carbonyls

Devoted to heterocyclizations of aliphatic and aromatic, -unsaturated carbonyls with various binucleophiles leading to three-, five-, six and seven-membered partially hydrogenated nitrogen-containing heterocycles. During the last decade interest in these classes of organic c- pounds has been experiencing a scientific renaissance owing to their significant role in biological processes in living cells and diverse effects on physiological activities. In addition, such compounds are also more prevalent from the vi- point of ''classical'' problems of organic chemistry, among them reactivity, chemo- and regioselectivity, tautomerism, conformational analysis and features of their electronic structure. The character of these problems in the case of partially hydrogenated heterocycles differs sufficiently from that for hetero- omatized and perhydrogenated heterocyclic compounds and investigations in this field very often lead to interesting and unusual results. Extensively characterized cyclocondensations of, -unsaturated carbonyls, their synthetic equivalents and their precursors are the most widespread, facile and generally valid pathway to dihydroazaheterocycles.

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Axon growth and guidance

The complexarchitectureofneuronal networks togetherwith the extraordinary associated functions make the nervous system a fascinating biological structure. The considerable work performed to explore this cellular machinery is nowadays successfulbecause the mysteryofnervous system developmentisbeing unravelled. As described in their outstanding review published 10 years ago in Science.' Marc Tessier-Lavigne and Corey Goodman-the pioneers of the molecular era of axon guidance-summarized the assembly of nervous system connections as a subtle game of attraction and repulsion of neuronal growth cones. The cellular ballet ensuring the formation of billions of synapses, which ultimately gives rise to the highest cognitive functions, is primarily orchestrated by a step-by-step mechanism of growth driven by multiple molecular cues. While our general concept of axon guidance remains identical, a profound evolution ofour knowledge ofthe molecular identityofthe guidance cues together with their interactions and signalling pathways occurred over the past ten years.

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Axially chiral compounds : Asymmetric synthesis and applications

Appearing widely in natural products, biologically active molecules, asymmetric chemistry, and material science, axially chiral motifs constitute the core backbones of the majority of chiral ligands and organocatalysts in asymmetric catalysis. In a new work of particular relevance to synthetic chemists, Axially Chiral Compounds: Asymmetric Synthesis and Applications delivers a clearly structured and authoritative volume covering the classification, characteristics, synthesis, and applications of axial chirality.

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Autoimmunity : Methods and protocols

Brings together a comprehensive and up-to-date collection of protocols that reflect the diverse experimental strategies. Chapters detail T-cell, macrophage characterization, neutrophil functional assays, organoid culture methods, spatial transcriptomics, RNA FISH, microRNA profiling, and ribosome profiling. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

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Autoformation et aide au diagnostic en hématologie avec le logiciel ADH = Self-study and diagnostic aid in hematology with ADH software

The software includes a rich iconography on blood and marrow cells which will complement the knowledge in cytology of hematologists. Certain cytological abnormalities encountered in certain pathologies are also presented.

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Attention and Performance in Computational Vision ; 2nd International Workshop, WAPCV 2004, Prague, Czech Republic, May 15, 2004, Revised Selected Papers

This book constitutes the thoroughly refereed post-proceedings of the Second International Workshop on Attention and Performance in Computational Vision, WAPCV 2004, held in Prague, Czech Republic in May 2004. The goal of this workshop was to provide an interdisciplinary forum tocommunicatecomputationalmodelsofvisualattentionfromvariousviewpoints,such as from computer vision, psychology, robotics and neuroscience. The motivation for - terdisciplinarity was communication and inspiration beyond the individual community, to focus discussion on computational modelling, to outline relevant objectives for p- formance comparison, to explore promising application domains, and to discuss these with reference to all related aspects of cognitive vision.

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Atopic eczema = الأكزيما التأتبية

Atopic dermatitis, commonly known as eczema, is a common chronic, relapsing skin disease characterized by pruritus, disrupted epidermal barrier function, and immunoglobulin E–mediated sensitization to food and environmental allergens. Atopic dermatitis is a complex disease that arises from interactions between genes and the environment. There are 3 classical stages of eczema: infantile, childhood, and adulthood. In this research, we studied several cases of patients with eczema, We have also developed a nano-biological therapy that is currently being tested on patients

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Atomistic approaches in modern biology : From quantum chemistry to molecular simulations

This volume of Topics in Current Chemistry presents an overview of atomistic theoreticalmethodsapplied tomolecular biologicalsystems. Itthus repesents abottom-upview of chemistryonbiologyfroma theoreticalperspective. The chapters arearrangedsuchthat important issuesareconsidered startingfrom a quantum mechanical perspective and proceeding to a molecular mechanics and molecular dynamics descriptiono fthemotionoftheelementaryparticles involved.which are responsible for the properties and function of biomolecules. Depending on the length and time scales relevant for a given phenomenon to be investigated, tailored theoretical methods are required to account for these. If one is interested in large scale motions of molecules, a molecul- mechnanics-based description willbeappropriate.

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Atlas of clinical hematology

The volume covers all the microscopic methods in hematology that form the basis of diagnosis as well as the results of modern immunologic, cytogenetic and molecular-genetic investigation. Special emphasis is placed on the cytogenetic and molecular-genetic characterization of biological entities that might form the basis for innovative therapies.

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Astrobiology : Future perspectives

Astrobiology, a new exciting interdisciplinary research field, seeks to unravel the origin and evolution of life wherever it might exist in the Universe. The current view of the origin of life on Earth is that it is strongly connected to the origin and evolution of our planet and, indeed, of the Universe as a whole. We are fortunate to be living in an era where centuries of speculation about the two ancient and fundamental problems: the origin of life and its prevalence in the Universe are being replaced by experimental science. The subject of Astrobiology can be approached from many different perspectives. This book is focused on abiogenic organic matter from the viewpoint of astronomy and planetary science and considers its potential relevance to the origins of life on Earth and elsewhere. Guided by the review papers in this book, the concluding chapter aims to identify key questions to motivate future research and stimulate astrobiological applications of current and future research facilities and space missions. Today’s rich array of new spacecraft, telescopes and dedicated scientists promises a steady flow of discoveries and insights that will ultimately lead us to the answers we seek.

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Aspects of physical biology : Biological water, protein solutions, transport and replication

The present volume focuses on three main subtopics (biological water, protein solutions as well as transport and replication), presenting for each of the them the on-going debates on recent results. The role of water in biological processes, the mechanisms of protein folding, the phases and cooperative effects in biological solutions, the thermodynamic description of replication, transport and neural activity, all are subjects that are revised in this volume, based on new experiments and new theoretical interpretations.

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Arum palaestenium in cancer therapies

Cancer is a very complicated sequence of disease conditions progressing gradually with a generalized loss of growth control.1–3 There were only a few options of cancer treatment for patients for many decades which include surgery, radiation therapy, and chemotherapy as single treatments or in combination.4,5 But recently, many pathways involved in cancer therapy progression and how they can be targeted has improved dramatically, with combinatorial strategies, involving multiple targeted therapies or “traditional” chemotherapeutics, such as the taxanes and platinum compounds, being found to have a synergistic effect.6 New approaches, such as drugs, biological molecules, and immune-mediated therapies, are being used for treatment.

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Artificial sight : Basic research, biomedical engineering, and clinical advances

Artificial sight is a frontier area of modern ophthalmology combining the multidisciplinary skills of surgical ophthalmology, biomedical engineering, biological physics, and psychophysical testing. Many scientific, engineering, and surgical challenges must be surmounted before widespread practical applications can be realized. The goal of Artificial Sight is to summarize the state-of-the-art research in this exciting area, and to describe some of the current approaches and initiatives that may help patients in a clinical setting.

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Artificial neural networks : Biological Inspirations – ICANN 2005 ; 15th International Conference, Warsaw, Poland, September 11-15, 2005, Proceedings, Part I

The two volume set LNCS 3696 and LNCS 3697 constitutes the refereed proceedings of the 15th International Conference on Artificial Neural Networks, ICANN 2005, held in Warsaw, Poland in September 2005. The over 600 papers submitted to ICANN 2005 were thoroughly reviewed and carefully selected for presentation. The first volume includes 106 contributions related to Biological Inspirations; topics addressed are modeling the brain and cognitive functions, development of cognitive powers in embodied systems spiking neural networks, associative memory models, models of biological functions, projects in the area of neuroIT, evolutionary and other biological inspirations, self-organizing maps and their applications, computer vision, face recognition and detection, sound and speech recognition, bioinformatics, biomedical applications, and information- theoretic concepts in biomedical data analysis.

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Artificial life models in software

Artificial Life Models in Software presents software tools, environments and realities dealing with creation, imitation and analysis of artefactual, virtual and living forms, written by those who personally design and produce software, hardware and art installations in artificial life, simulated complex systems and virtual worlds. This timely volume offers a nearly exhaustive overview and original analysis of major non-profit artificial life software packages. The carefully selected topics include: · simulation of real and imaginary life forms and their evolution · self-organization · emergent behaviours · swarm intelligence · evolutionary robotics · agent-based simulations · adaptive, complex and biologically inspired ecosystems · creative computer art There has long been a need within the academic and research community for an informal introduction and guidance to modern software tools for modelling and simulation of life-like phenomena – Artificial Life Models in Software fills this gap and provides invaluable information to both professional and amateur readers, offering detailed reviews of contemporary software for artificial life.

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Artificial intelligence in theory and practice ; IFIP 19th World Computer Congress, TC 12: IFIP AI 2006 Stream, August 21-24, 2006, Santiago, Chile

The IFIP series publishes state-of-the-art results in the sciences and technologies of information and communication. The scope of the series includes: foundations of computer science; software theory and practice; education; computer applications in technology; communication systems; systems modeling and optimization; information systems; computers and society; computer systems technology; security and protection in information processing systems; artificial intelligence; and human-computer interaction. Proceedings and post-proceedings of referred international conferences in computer science and interdisciplinary fields are featured.

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Artificial intelligence applied to medical imaging and computational biology

Medical imaging and computational biology continuously pose new fundamental medical and biological questions that often give rise to novel challenges in Artificial Intelligence. These research fields present an increasing need for the application of cutting-edge computational approaches that generally involve machine learning or computational intelligence techniques, which can effectively perform bioimage and biosignal processing in different clinical areas.

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Arterial Grafting for Coronary Artery Bypass Surgery

The second edition of this book provides updated knowledge about the biological characteristics and clinical use of arterial grafts for coronary artery bypass surgery. The reader will find first-hand information on arterial grafts as well as vein grafts with regard to biological characteristics, clinical use including off-pump coronary bypass grafting surgery, results, and future developments. Written by world-renowned cardiac surgeons and cardiovascular research scientists working in this area.

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Arrhythmogenic RV cardiomyopathy / dysplasia : Recent advances

This book covers all aspects (biological, pathological, genetic, clinical and therapeutical) of arrhythmogenic right ventricular cardiomyopathy/dysplasia, a recent cardiomyopathy which represents a very high risk of sudden death in the young and in athletes. The monograph presents the results of 5-year research program on ARVC/D supported by grants of both the European Commission and the NIH, which enabled the discovery of seven disease-causing genes, thus opening new avenues for the early identification of affected patients and for sudden death prevention.

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