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الصفحة 23
Late Effects of Cancer Treatment on Normal Tissues
Based on the LENT V NCI-sponsored meeting held in May 2004 and the CURED I conference held in 2006. It addresses a number of critical topics relating to late effects, such as mechanisms of injury, the role of screening, options for interventions, second malignancies, and prevention.
Lassativi : Impiego razionale dei lassativi nella stipsi = assatives : Rational use of laxatives in constipation
An extensive compendium on laxatives. It covers all aspects of the clinical use of laxatives complete with physiological information related to constipation. The mechanisms of action of the main classes of laxatives are widely described. The text contains illustrations that help to understand the origins of plant laxatives and the pharmacology of the most interesting ones. Doctors, pharmacists, herbalists, nurses and students will find this volume interesting and useful.
Lantibiotics as alternative therapeutics
Explores alternative therapeutics, lantibiotics and other novel drugs. This book provides concrete information to readers regarding lantibiotics and various types of antimicrobial peptides with their mode of actions in treating various multidrug resistant organisms. It explains various techniques that are involved in analyzing antimicrobial peptides and their mode of actions. The development of antibiotic resistance has now reached a point of crisis where innovative methods and application of novel compounds and methods are required to prevent the spread of drug resistant infections.
Land-Use and Land-Cover Change : Local Processes and Global Impacts
The book presents recent estimates of the rates in changes of major land classes such as forest, cropland and pasture. Among the causative mechanisms behind land change, synergetic factor combinations are found to be more common than single key factor explanations. Aggregated globally, multiple impacts of local land changes are shown to significantly affect central aspects of Earth System functioning. Innovative developments and applications in the fields of modeling and scenario construction are presented. Finally, conclusions are drawn about the most pressing implications for the design of appropriate intervention policies, and on new directions and frontiers of research.
Landslides in research, theory and practice ; Proceedings of the 8th International Symposium on Landslides held in Cardiff on 26–30 June 2000
Contains vital information from throughout the world on landslide and slope instability problems. Every four years the worlds leading scientists and engineers dealing with landslides, have the opportunity to meet up and engage in the exchange of ideas and experiences at a symposium run under the auspices of ISSMGE Technical Committee 11. These volumes, taken from the 8th symposium in the series, detail investigations into landslide causes, mechanisms and hazards, together with accounts of monitoring and mapping.
Landslides : Risk Analysis and Sustainable Disaster Management
Based on contributions to the first General Assembly of the International Consortium on Landslides, this reference and status report emphasizes the mechanisms of different types of landslides, landslide risk analysis, and sustainable disaster management. It comprises the achievements of the ICL over the past three years, since the Kyoto assembly. It consists of three parts: research results of the International Programme on Landslides (IPL); contributions on landslide risk analysis; and articles on sustainable disaster management. The contributions reflect a wide range of topics and concerns, randing from field studies, identification of objects of cultural heritage at landslide risk, as well as landslide countermeasures.
Knowledge-Driven Computing : Knowledge Engineering and Intelligent Computations
Knowledge-Driven Computing constitutes an emerging area of intensive research located at the intersection of Computational Intelligence and Knowledge Engineering with strong mathematical foundations. It embraces methods and approaches coming from diverse computational paradigms, such as evolutionary computation and nature-inspired algorithms, logic programming and constraint programming, rule-based systems, fuzzy sets and many others. The use of various knowledge representation formalisms and knowledge processing and computing paradigms is oriented towards the efficient resolution of computationally complex and difficult problems.
Knowledge Solutions : Tools, Methods, and Approaches to Drive Organizational Performance
Covers topics in knowledge management and competence in strategy development, management techniques, collaboration mechanisms, knowledge sharing and learning, as well as knowledge capture and storage. Presented in accessible “chunks,” it includes more than 120 topics that are essential to high-performance organizations. The extensive use of quotes by respected experts juxtaposed with relevant research to counterpoint or lend weight to key concepts; “cheat sheets” that simplify access and reference to individual articles; as well as the grouping of many of these topics under recurrent themes make this book unique. In addition, it provides scalable tried-and-tested tools, method and approaches for improved organizational effectiveness.
Kinetics of Water-Rock Interaction
Systems at the surface of the Earth are continually responding to energy inputs derived from solar radiation or from the radiogenic heat in the interior. These energy inputs drive plate movements and erosion, exposing metastable mineral phases at the Earth’s surface. In addition, these energy fluxes are harvested and transformed by living organisms. As long as these processes persist, chemical disequilibrium at the Earth’s surface will be perpetuated. Chemical disequilibrium is also driven by human activities related to production of food, extraction of water and energy resources, and burial of wastes. To understand how the surface of the Earth will change over time, we must understand the rates at which reactions occur and the chemical feedbacks that relate these reactions across extreme temporal and spatial scales. This book addresses fundamental and applied questions concerning the rates of water-rock interactions driven by tectonic, climatic, and anthropogenic forcings.
Ketamine for Treatment-Resistant Depression : Neurobiology and Applications
Ketamine for Treatment-Resistant Depression: Neurobiology and Applications provides a simple, evidence-based overview for neuropsychiatrists and translational researchers on this medication, its mechanisms of actions, eligibility of patients for treatment, and the preparation and implementation of ketamine clinics.
Kaposi Sarcoma Herpesvirus : New Perspectives
Since the identificationof two sequences fromKSHV,wehave learnedmuch about this pathogen as reflected in this book. As it turned out, KSHV itself encodes for a number of cytokines, and induces cellular cytokine secretion, contributing to tumour growth. Moreover, KSHV vFLIP targets the IKKNFκB axis to encourage the inflammatory microenvironment observed by Gallo and his colleagues. KSHV continues to elucidate both mechanisms of viral oncogenesis, and cellular and immune pathways involved in non-viral driven neoplasia.
Jets from Young Stars : Models and Constraints
This volume contains the edited lecture notes of the First JETSET School on Jets from Young Stars: Models and Constraints, held by the Marie Curie Research and Training Network on JET Simulations, Experiments and Theory. At this school the lecturers gave an introduction to observational properties and basic models describing the launching and collimation mechanisms of jets.
IUTAM Symposium on Vibration Control of Nonlinear Mechanisms and Structures ; Proceedings of the IUTAM Symposium held in Munich, Germany, 18-22 July 2005
The objective of the Symposium was to evaluate the limits of performance that can beachievedby controlling the dynamics, and to point out gaps in present research and give links for areas offuture research.Mainly, it brought together leading experts from quite different areas presenting theirpoints of view.
IUTAM Symposium on Mechanics and Reliability of Actuating Materials ; Proceedings of the IUTAM Symposium held in Beijing, China, 1-3 September, 2004
The general assembly of IUTAM approved in August, 2002 at Cambridge University, UK, a proposal to hold an IUTAM symposium to summarize the relevant research findings. The main themes of the symposium are: (i) the constitutive relations of actuating materials that couple mechanical, electrical, thermal and magnetic properties, as well as incorporate phase transformation and domain switch; (ii) the physical mechanisms of deformation, damage, and fatigue crack growth of actuating materials; (iii) the development of failure-resilient approaches that base on the macro-, meso-, and micro-mechanics analyses; (iv) the investigation of microstructural evolution, stability of phase transformation, and size effects of ferroelectric ceramics, shape memory alloys, actuating polymers, and bio-actuating materials.
Complexity and Artificial Markets
In recent years, agent-based simulation has become a widely accepted tool when dealing with complexity in economics and other social sciences. The contributions presented in this book apply agent-based methods to derive results from complex models related to market mechanisms, evolution, decision making, and information economics. In addition, the applicability of agent-based methods to complex problems in economics is discussed from a methodological perspective. The papers presented in this collection combine approaches from economics, finance, computer science, natural sciences, philosophy, and cognitive sciences.
Complement and Kidney Disease
It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinct human kidney diseases is caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms allowed establishing new diagnostic and promising therapeutic approaches for several human kidney diseases. Molecular biology, clinics and therapy are discussed in this volume.
Comparing the performance of the Damascus securities exchange with the performance of the Amman stock exchange
Financial markets are one of the most important economic components in any economy, as they form a major axis for financing businesses and companies and stimulating economic growth. Financial markets provide the necessary liquidity to finance projects and economic activities, and also provide mechanisms for investors to invest and achieve financial returns on their money. Financial markets are also an important indicator of the health of the economy, reflecting their activity and performance in the economic, political, and social situation in different countries...
Comparative genomics : Methods and protocols
Provides new and updated chapters covering computational and mathematical techniques and concepts related to the field of comparative genomics. The topics covered in the chapters range from those that address general techniques and concepts that apply to all organisms to others that are specialized and apply to specific biological systems such as viruses, bacteria, nematodes, and insects.
Communication in Plants : Neuronal Aspects of Plant Life
Plant neurobiology is a newly emerging field of plant sciences. It covers signalling and communication at all levels of biological organization – from molecules up to ecological communities. In this book, plants are presented as intelligent and social organisms with complex forms of communication and information processing. Authors from diverse backgrounds such as molecular and cellular biology, electrophysiology, as well as ecology treat the most important aspects of plant communication, including the plant immune system, abilities of plants to recognize self, signal transduction, receptors, plant neurotransmitters and plant neurophysiology. Further, plants are able to recognize the identity of herbivores and organize the defence responses accordingly. The similarities in animal and plant neuronal/immune systems are discussed too. All these hidden aspects of plant life and behaviour will stimulate further intense investigations in order to understand the communicative plants in their whole complexity.
Clinical metabolomics applications in genetic diseases
Helps readers discover the forefront of personalized medicine on clinical metabolomics and its applications in genetic diseases. This comprehensive guide offers a functional relationship map between cell components and genetic variations in various diseases, providing insights that can be applied to personalized medicine. Covers the latest developments in metabolomics for health, with practical guidance for clinical experts looking to advance their laboratory techniques and career. The metabolomics profile is a powerful tool that has revolutionized our understanding of the relationship between genetics, clinical readouts, and disease outcomes. By integrating metabolomics with genomics and clinical phenotypes, the authors have developed diagnostic and prediction models that have vastly improved patient outcomes and deepened the understanding of disease mechanisms.
