الصفحة 23
الصفحة 23
Biomarkers for alzheimer’s disease drug development
Aims to build a new generation of experts with a broader understanding of key topics in the Alzheimer’s disease field. Chapters guide readers through innovative approaches to the discovery of novel biomarkers in cerebrospinal fluid, innovation in blood-based biomarkers, a comprehensive overview of magnetic resonance imaging and molecular imaging approaches and their value for developing drugs for Alzheimer’s disease, cutting-edge developments in neuropathology and their relevance for Alzheimer’s disease trials, novel genomic strategies for biomarker development, and related topics including neuropsychological testing and advanced analytical methods.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Biological Low-Voltage Scanning Electron Microscopy
Biological Low-Voltage Scanning Electron Microscopy is the first book to address both of these aspects of biological LVSEM. After providing a thorough description of the unique advantages and the operating constraints related to operating a scanning electron microscope at low beam voltage, the remainder of book focuses on the the best way to image all types of plant and animal cells and covers specimens that range from macromolecules to the surfaces revealed by de-embedding resin-embedded samples. Advanced specimen preparation techniques such as cryo-LVSEM, and immuno-gold-LVSEM are fully covered, as is x-ray microanalysis at low beam voltage and live-time stereo imaging. The preparative protocols provided represent the distilled essence of the experience of a group of world-renowned authors who have, for many decades, been instrumental in developing and applying new approaches to LVSEM to support their own biological research.
Bioimaging in Neurodegeneration
offers both the physician and researcher a critical survey of the best new technologies for studying neurodegeneration, as well as describing their optimal use in the diagnosis and treatment of specific neurodegenerative diseases
Bioimage Data Analysis Workflows
This book provides students and researchers in the life sciences with essential practical information on how to quantitatively analyze data images. It refrains from focusing on theory, and instead uses practical examples and step-by step protocols to familiarize readers with the most commonly used image processing and analysis platforms such as ImageJ, MatLab and Python.
Bioengineering in cell and tissue research
This book reviews the latest technological developments of bioengineering approaches in cell and tissue research. It is meant to have life and spirit, and to become a pioneer in technology and sciences, especially the life science. The chapters are written by excellent scientists on advanced, frontier technology and address scientific questions that need considerable thinking in terms of engineering.
Biocompatible nanocomposites : From synthesis to applications
Presents a focused overview of biocompatible nanocomposites, emphasizing recent advancements in material design, synthesis techniques, and their expanding applications in biomedicine. It spans key areas such as regenerative medicine, drug delivery, cancer therapy, biosensing, diagnostic imaging, and vaccine delivery —illustrating how these materials are transforming modern healthcare. The book reviews widely used biomaterials including polycaprolactone, bioactive ceramics, and polymer-based hybrids, discussing their roles in cardiovascular, orthopedic, dental, maxillofacial, and ophthalmic applications.
Bio-Applications of Nanoparticles
In this edited book, we highlight the central players in the Bionanotechnology field, which are the nanostructures and biomolecules. The book starts by describing how nanostructures are synthesized and by describing the wide variety of nanostructures available for biological research and applications. Also shown are the techniques used to synthesize a wide variety of biological molecules. Next, there is a focus on the assembly of nanostructures with biological molecules, which could lead to the design of multi-functional nanosystems. In the following chapters, examples of the unique properties of nanostructures are provided along with the current applications of these nanostructures in biology and medicine. Some applications include the use of gold nanoparticles in diagnostic applications, quantum dots and silica nanoparticles for imaging, and liposomes for drug delivery. In the final chapters of the book, the toxicity of nanostructures are described. This book provides broad examples of current developments in Bionanotechnology research and would be an excellent introduction to the field.
Biliary Lithiasis : Basic Science, Current Diagnosis and Management
The book provides an overview on biliary lithiasis and all its clinical pictures, twenty years after the first laparoscopic cholecystectomy. The gallbladder, the main bile duct and intra-hepatic stones, in their uncomplicated and complicated forms are illustrated.
Benign anorectal diseases : Diagnosis with endoanal and endorectal ultrasound and new treatment options
New three-dimensional endoanal and endorectal ultrasonographic and magnetic resonance imaging techniques have given better insight into the complex anatomy of the pelvic floor and its pathologic modification in benign anorectal diseases. Obstetrical events leading to fecal incontinence in females, the relationship between fistulous tracks and the sphincter complex, and mechanisms of obstructed defecation syndrome can now be accurately evaluated, which is of fundamental importance for decision making.
Basics of PET Imaging : Physics, Chemistry, and Regulations
This unparalleled text on the basics of PET imaging technology is an ideal resource for technologists and residents preparing for board examinations. the book also serves as a useful reference for practicing nuclear medicine professionals. Chapters are concise but comprehensive and emphasize the fundamentals, including physics, instrumentation and data acquisition, image reconstruction, production of PET radionuclides and radiopharmaceuticals, and regulatory and reimbursement issues.
Balloon Kyphoplasty
This book focuses on balloon kyphoplasty and alter- tive minimally invasive treatments for stabilization of osteoporotic vertebral fractures. The optimal treatment of a patient with osteoporotic vertebral fractures requires an interdisciplinary - proach, and therefore our book draws on the expertise of orthopedic surgeons, traumatologists and neu- surgeons, and also includes a chapter on medical treatment.
Bacterial secretion systems : Methods and protocols
Cover techniques used to study secretion systems. Chapters focus on identifying and localizing the different subunits, defining interactions within subunits, monitoring conformational changes, purifying and imaging of large complexes, defining the assembly pathway by fluorescence microscopy and the role of energy during assembly and/or secretion, identifying secreted effectors as well as using reporters to follow effector transport. Written in the highly
Atlas of topographical and pathotopographical anatomy of the head and neck
Presents the ultrasonic topographical and pathotopographical anatomy of the head and neck, offering further detail into these important areas for use by medical professionals. This atlas of topographic and pathotopographic human anatomy is a fundamental and practically important book designed for doctors of all specializations and students of medical schools. Here you can find almost everything that is connected with the topographic and pathotopographic human anatomy, including original graphs of logical structures of topographic anatomy and development of congenital abnormalities, topography of different areas in layers, pathotopography, computer and magnetic resonance imaging (MRI) of topographic and pathotopographic anatomy.
Atlas of Regional Anatomy of the Brain Using MRI : with functional correlations
The volume provides a unique review of the essential topographical anatomy of the brain from an MRI perspective, correlating high-quality anatomical plates with the corresponding high-resolution MRI images. The book includes a historical review of brain mapping and an analysis of the essential reference planes used for the study of the human brain. Subsequent chapters provide a detailed review of the sulcal and the gyral anatomy of the human cortex, guiding the reader through an interpretation of the individual brain atlas provided by high-resolution MRI.
Atlas of Psoriatic Arthritis
A visual guide to the complex and inter-related diseases of psoriatic arthritis and psoriasis, this volume contains more than 150 images spanning a wide spectrum of variations of the disease.
Atlas of Practical Applications of Cardiovascular Magnetic Resonance
The Atlas of Practical Applications of Cardiovascular Magnetic Resonance contains over two hundred illustrations and a Glossary of terms. This atlas will assist cardiologists to determine when a CMR exam is useful for diagnosis and provide details on how to plan and read CMR studies.
Atlas of Pelvic Floor Ultrasound
Atlas of Pelvic Floor Ultrasound provides an introduction to pelvic floor imaging, as well as a resource to be used during initial and more advanced practice.
Atlas of oral and maxillofacial radiology
Presents an extensive case collection of both common and less common conditions of the jaws and teeth. Focusing on the essentials of radiologic interpretation, this is a go-to companion for clinicians in everyday practice who have radiologically identified a potential abnormality, as well as a comprehensive study guide for students at all levels of dentistry, surgery and radiology. Unique lesion-based problem solving chapter makes this an easy-to-use reference in a clinical settingIncludes 2D intraoral radiography, the panoramic radiograph, cone beam CT, multidetector CT and MRIMultiple cases are presented in order to demonstrate the variation in the radiological appearances of conditions affecting the jaws and teethSpecial focus on conditions where diagnostic imaging may substantially contribute to diagnosisFeatures a useful chapter covering the temporomandibular joint
Atlas of Morphology and Functional Anatomy of the Brain
Divided into a morphological and a functional imaging section. The morphological atlas includes 3D surface images, axial, coronal, and sagittal scans acquired with high-definition T2 fast spin echo (FSE) sequences, and standard and inverted-contrast images. The MR scans are shown side by side with the corresponding anatomical brain sections, provided by Prof. Henri Duvernoy, for more effective comparison. The anatomical nomenclature adopted for both the MR and the anatomical images is listed in an jacket flap for easier consultation.
Atlas of mandibular and maxillary reconstruction with the fibula flap : A step-by-step approach
Deals with the standard technique used for reconstructing the mandible and the maxilla - the fibula flap. The reader will find useful information on all issues that are important in the surgical procedure, including the use of CAD-CAM technology (Computer Assisted Technology), bone synthesis and flap modelling. The editors draw on their 30 years of experience to provide a step-by-step description of this surgical procedure. With the help of numerous illustrations, the reader will learn the technical, functional and aesthetic developments since 1989 when this technique was first described.
