الصفحة 22
الصفحة 22
Latency Strategies of Herpesviruses
This is the first book dealing with the intricate epigenetic mechanisms (DNA methylation, histone modification, alteration of chromatin structure) that regulate latency-associated transcription. Special attention is given to immune evasion "tricks" blocking immune responses to herpesvirus infected cells and viral RNAs and proteins involved in malignant transformation.
Large-Scale Knowledge Resources. Construction and Application ; 3rd International Conference on Large-Scale Knowledge Resources, LKR 2008, Tokyo, Japan, March 3-5, 2008. Proceedings
At the start of the 21st century,we are now well on the way to wards aknowled- intensive society, in which knowledge plays ever more important roles. Thus, research interest should inevitably shift from information to knowledge, with the problems of building, organizing, maintaining and utilizing knowledge - coming centralissues in a wide varietyof felds. The 21stCentury COE program “Framework for Systematization and Application of Large-scale Knowledge - sources (COE-LKR)” conducted by the Tokyo Institute of Technology is one of several early attempts worldwide to address these important issues. Inspired by this project, LKR2008 aimed at bringing together diverse contributions in cognitive science, computer science, education and linguistics to explore design, construction, extension, maintenance, validation and application of knowledge.
Landscapes, Genomics and Transgenic Conifers
What is the future of genetically modified (or transgenic) conifer plantations? The content of this edited volume Landscapes, Genomics and Transgenic Conifers addresses this question directly - and indirectly - using language drawn from policy, forest history, genomics, metabolism, pollen dispersal and gene flow, landscape ecology, evolution, economics, technology transfer and regulatory oversight. Although the book takes its title from a Nicholas School Leadership forum held November 17-19, 2004 at Duke University, its de novo contents move past the forum’s deliberations. The result is a trans-disciplinary book composed of 14 chapters written by a total of 31 authors working in North America, South America, Europe and Africa.
Laboratory Guide to the Methods in Biochemical Genetics
This manual deals specifically with laboratory approaches to diagnosing inborn errors of metabolism. The key feature is that each chapter is sufficiently detailed so that any individual can adopt the described method into their own respective laboratory.
La genetica nell’infertilità maschile = Genetics in male infertility
The notable recent cognitive advances in the field of cytogenetics and molecular genetics have made it possible to identify chromosomal anomalies and gene mutations responsible for numerous male infertility, which were completely ignored until recently. The fact is not without relevance, if the principle is valid that the recognition of the causes of a disease is also the first and necessary approach towards its correct therapy. With this publication, the authors wanted to offer specialists working in the field of assisted reproduction an update on this complex subject, dealing with both genetic causes in male infertility and infertility in genetic diseases.
Knowledge-Driven Computing : Knowledge Engineering and Intelligent Computations
Knowledge-Driven Computing constitutes an emerging area of intensive research located at the intersection of Computational Intelligence and Knowledge Engineering with strong mathematical foundations. It embraces methods and approaches coming from diverse computational paradigms, such as evolutionary computation and nature-inspired algorithms, logic programming and constraint programming, rule-based systems, fuzzy sets and many others. The use of various knowledge representation formalisms and knowledge processing and computing paradigms is oriented towards the efficient resolution of computationally complex and difficult problems.
Kidney complications & transplantation
Kidney diseases are worldwide public health problems with a high cost and increasing incidence. By revealing the genetic and cellular mechanism behind mammalian kidney development, better diagnostic methods and novel therapies can be expected to be developed. The mammalian kidney is a typical organ that develops on the basis of sequential and reciprocal cell and tissue interactions. Pyelonephritis, Glomerulonephritis, Kidney stones, Nephrotic syndrome, and Acute or chronic kidney failure are the most complications in the kidney kingdom, so that living kidney transplantation has become the preferred treatment for those patients who can’t have the powerful capacity of the kidney function, and here it has a very rejection risk in the first month and we can controlled in this situation with long term immunosuppressant therapy involved in the post-transplantation protocol.
Job Scheduling Strategies for Parallel Processing ; Vol. 3834 : 11th International Workshop, JSSPP 2005, Cambridge, MA, USA, June 19, 2005, Revised Selected Papers
Constitutes the refereed postproceedings of the 11th International Workshop on Job Scheduling Strategies for Parallel Processing, 2005, held in conjunction with the 19th ACM International Conference on Supercomputing. This book covers a range of parallel architectures, from distributed grids, through clusters, to massively-parallel supercomputers.
Issues of Decapod Crustacean Biology
This volume presents the proceedings of the eighth Colloquium Crustacea Decapoda Mediterranea, which was held at the Ionian University on Corfu Island, Greece, from 2 to 6 September 2002, and reflects recent advancements in decapod crustacean research. The meeting is the oldest European carcinological event, organized regularly at 3-year intervals since 1972. Although focused on the Mediterranean Sea, worldwide contributions provided a forum for fruitful contact and scientific exchange. The book covers up-to-date issues in decapod crustacean research, including genetics, morphology, reproduction, ecology, behaviour and fisheries, and it is primarily aimed at scientists interested in decapod crustacean research, but other scientists and decision-makers working on marine ecology and fisheries will also find up-to-date information on relevant issues.
Computational and Ambient Intelligence ; 9th International Work-Conference on Artificial Neural Networks, IWANN 2007, San Sebastián, Spain, June 20-22, 2007, Proceedings
This biennial meeting focuses on the foundations, theory, models and applications of systems inspired by nature (neural networks, fuzzy logic and evo- tionary systems).These new computational techniques are used in applications that try to bring a new situation of well-being to the user. The conjunction of a more and more miniaturized hardware together with the growing computational intelligence embodied in this hardware leads us towards fully integrated embedded systems-on- chip and opens the door for truly ubiquitous electronics.
Comprehensive biochemistry for dentistry : Textbook for dental students
Combines fundamental concepts of biochemistry and the dental sciences to provide an authentic, coherent and comprehensive text for dental students. It describes in simple language the intricate pathophysiology of biomolecules in health and in diseases of dental and oral tissues. This book also describes the evolution of biochemistry in a chronological order, provides information about the fundamental chemical structure, classification and biological significance of biomolecules, vitamins and hormones, enriched with flow charts and diagrams for easy understanding and quick reference. It includes chapters on nucleic acids, nutrition and serum enzymes and organ function tests, and offers an innovative approach to familiarize dental students with the biochemical composition of enamel, dentine, cementum and saliva, explaining the biochemical basis of dental caries, periodontal diseases, role of fluorides in caries prophylaxis, fluoride toxicity, and the role of amino acids as anti-hypersensitive agents
Complications following surgery of maxillary impacted canine and their management
Investigates the impaction of maxillary canines, a dental condition where the canines fail to erupt within the expected timeframe despite complete root formation. The research highlights various contributory factors, including genetic predispositions, lack of space due to early loss of deciduous molars, follicular cysts, and the presence of supernumerary teeth. The study explores the etiology of both palatal and buccal impactions, noting the significant role of genetic factors, tooth size, arch length discrepancies, and abnormal tooth development. Treatment options, including orthodontic interventions and surgical extractions, are discussed in the context of the impacted tooth's position and associated complications.
Complex Scheduling
This book deals with such complex scheduling problems and methods to solve them. It consists of three parts: The ?rst part (Chapters 1 and 2) contains a description of basic scheduling models with applications and an introduction into discrete optimization (covering complexity, shortest path algorithms, linear programming, network ?ow algorithms and general optimization methods). In the second part (Chapter 3) resource-constrained project scheduling problems are considered. Especially, methods like constraint propagation, branch-a- bound algorithms and heuristic procedures are described. Furthermore, lower bounds and general objective functions are discussed.
Complement and Kidney Disease
It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinct human kidney diseases is caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms allowed establishing new diagnostic and promising therapeutic approaches for several human kidney diseases. Molecular biology, clinics and therapy are discussed in this volume.
Comparative genomics ; International Workshop, RECOMB-CG 2008, Paris, France, October 13-15, 2008. Proceedings
This book constitutes the refereed proceedings of the 6th RECOMB Comparative Genomics Satellite Workshop, RECOMB-CG 2008, held in Paris, France, in October 2008.
Communication in Cancer Care
This textbook represents one of the most fnding a way to support their loved one and help comprehensive as well as clinically relevant - them maintain hope, advocate on their behalf, ited volumes on the subject of communication help collect and integrate information. Tis must in cancer care to appear to date.
Common Eye Diseases and their Management
There have been significant advances in the diagnosis and management of eye disease since the last edition of Common Eye Diseases and their Management was published. The specialty has developed more subspecialties, and the referring doctor has to have a good knowledge of these in order to make appropriate referrals. An increased emphasis on screening has made it necessary for the primary care doctor to have a basic knowledge of eye diseases. This applies particularly to glaucoma and diabetic eye disease. The management of eye conditions in the elderly is also an important and increasing primary care problem.
Clinical Neuroembryology : Development and Developmental Disorders of the Human Central Nervous System
Combines data from human embryology, animal research and developmental neuropathology. This book provides an overview of the development of the human Central Nervous System (CNS) in the context of its many developmental disorders due to genetic, environmental and hypoxic causes. It highlights numerous clinical cases and contains over 400 figures.
Clinical metabolomics applications in genetic diseases
Helps readers discover the forefront of personalized medicine on clinical metabolomics and its applications in genetic diseases. This comprehensive guide offers a functional relationship map between cell components and genetic variations in various diseases, providing insights that can be applied to personalized medicine. Covers the latest developments in metabolomics for health, with practical guidance for clinical experts looking to advance their laboratory techniques and career. The metabolomics profile is a powerful tool that has revolutionized our understanding of the relationship between genetics, clinical readouts, and disease outcomes. By integrating metabolomics with genomics and clinical phenotypes, the authors have developed diagnostic and prediction models that have vastly improved patient outcomes and deepened the understanding of disease mechanisms.
Clinical Approaches in Endodontic Regeneration : Current and Emerging Therapeutic Perspectives
This book combines explanation of the scientific base underpinning vital pulp treatment with description of current and emerging trends in clinical practice. It guides the reader through modern views on pulp diagnostics, deep caries, and pulp exposure management, leading to an analysis of the biological aspects of regenerative techniques such as angiogenesis, neurogenesis, inflammation, and epigenetics.
