الصفحة 22
الصفحة 22
Genomic Disorders : The Genomic Basis of Disease
In Genomic Disorders: The Genomic Basis of Disease, distinguished experts and pioneers in the field of genomics and genome rearrangements summarize and synthesize the tremendous amount of data now available in the postgenomic era on the structural features, architecture, and evolution of the human genome.
Genome editing in drug discovery
In Genome Editing in Drug Discovery, a team of distinguished biologists delivers a comprehensive exploration of genome editing in the drug discovery process, with coverage of the technology’s history, current issues and techniques, and future perspectives and research directions. The book discusses techniques for disease modeling, target identification with CRISPR, safety studies, therapeutic editing, and intellectual property issues.
Genetic Engineering of Mesenchymal Stem Cells
MSC (mesenchymal stem cells) have been reported to initiate revascularization after injury, to facilitate engraftment of blood-forming stem cells, and to reduce the incidence of graft-vs. host disease through their immune-suppressive qualities. Finally, bone marrow-derived MSC have been reported to home to areas of solid tumor revascularization, and thus may be used as delivery vehicles to target ablative agents into dividing tumor cells. Recently the characteristics of human MSC from adipose (fat) tissue have also been identified. The possibility of repairing tissues, speeding stem cell engraftment, and targeting solid tumors for specific killing, using MSC easily harvested from bone marrow, or better yet, from unwanted fat tissue, holds broad appeal, and is an intriguing possibility that could have dramatic effect on health care. This book has information on how to isolate, grow, and characterize MSC from marrow and fat, and gives important insight into how these cells may be used for gene delivery and cellular therapies in the future. Updates on emerging clinical trials are given.
Genetic algorithms: theory, design and programming
We present a series of scientific contributions that delve into the intricate theoretical foundations and practical nuances of genetic algorithms (GAs). Beyond the academic realm, GAs have demonstrated profound applications in societal decision-making and engineering optimization, showcased through real-world examples and case studies. A dedicated section on programming principles offers a thorough guide for implementing GAs across diverse languages. This edition, tailored for researchers and academics, serves as a testament to the scientific advancements within the field, inviting readers to explore the nuanced journey from theoretical constructs to pragmatic applications in the dynamic landscape of GAs.
Gastrointestinal Cancer
Gastrointestinal cancer includes cancer of the digestive system - the esophagus, colon, rectum, anus, liver, pancreas, and other digestive organs. Taken as a whole, there are an estimated 250,600 new cases in the US. Colon and rectum cancer is the third leading cause of cancer and cancer deaths in the US. Gastrointestinal Cancer is the third volume in the M.D. Anderson Cancer Care series, featuring the current standard approach to GI cancer care from the experts at M.D. Anderson Cancer Center. Designed for the practicing oncologist, this clinical guidebook allows for quick, authoritative access to the latest and best multimodality therapies. Topics covered in this volume include AJCC staging of gastrointestinal malignancies, recent advances in histopathology of gastroinestinal cancers, imaging techniques and endoscopy in the management of GI malignancies, colorectal cancer, liver cancer, gastric cancer, esophageal cancer, anal cancer, and palliative therapy. Each of the 20 chapters ends with an up-to-date list of suggested readings, as well as "key practice points" highlighting the most principles and practices of each chapter for at-a-glance reference. More than 80 illustrations complement the text. This thorough, practical volume is the essential clinical guide for the oncologists, surgeons, and all physicians involved in the care of patients with GI cancer.
Galaxies in Turmoil : The Active and Starburst Galaxies and the Black Holes That Drive Them
Active galaxies involve some of the most extreme conditions and some of the most intriguing phenomena found anywhere in the universe. Research students - and even established research astronomers - will also find this book invaluable as a quick reference to the properties of, and phenomena within, those types of active galaxies that may be outside their specialisms.
Fuzzy Quantifiers : A Computational Theory
Almost all", "many", "some": fuzzy quantifiers are vital for effective communication in natural language (NL). This monograph pursues an axiomatic method to achieve a reliable interpretation of these quantifiers in technical applications of fuzzy quantification. Unlike existing work in this area, it targets a much broader class of quantificational phenomena which includes all cases usually considered in linguistics. The topics addressed in the monograph run the gamut from the introduction of the theoretical framework for analysing fuzzy quantification, the formalization of semantical requirements on models of fuzzy quantification, the construction and detailed study of prototypical models which conform to the linguistic desiderata, the development of algorithms for implementing the main types of quantifiers in these models, and finally a preview to fuzzy branching quantifications which might be necessary for modelling NL sentences involving more than one quantifier.
Fuzzy multi-criteria decision making : Theory and applications with recent developments
In trying to make a satisfactory decision when imprecise and multicriteria situations are involved, a decision maker has to use a fuzzy multicriteria decision making method. Fuzzy Multi-Criteria Decision Making (MCDM) presents fuzzy multiattribute and multiobjective decision-making methodologies by distinguished MCDM researchers. In summarizing the concepts and results of the most popular fuzzy multicriteria methods, using numerical examples, this work examines all the fuzzy multicriteria methods recently developed, such as fuzzy AHP, fuzzy TOPSIS, interactive fuzzy multiobjective stochastic linear programming, fuzzy multiobjective dynamic programming, grey fuzzy multiobjective optimization, fuzzy multiobjective geometric programming, and more.
Fuzzy Control : Fundamentals, Stability and Design of Fuzzy Controllers
The book provides a critical discussion of fuzzy controllers from the perspective of classical control theory. Special emphases are placed on topics that are of importance for industrial applications, like (self-) tuning of fuzzy controllers, optimisation and stability analysis. The book is written as a textbook for graduate students as well as a comprehensive reference book about fuzzy control for researchers and application engineers. Starting with a detailed introduction to fuzzy systems and control theory the reader is guided to up-to-date research results.
Fundamentals of Virtual Colonoscopy
Virtual colonoscopy is a rapidly developing technique that can be performed in an outpatient setting without sedation. It promises to be safer and less intrusive than conventional diagnostic tests for colon cancer and is attractive to patients. Despite the attention that virtual colonoscopy has received among medical professionals, many lack an understanding of the basics of this cutting-edge procedure. Renowned radiologist Abraham Dachman, MD, and a distinguished group of international contributors have prepared a fundamentals book that fills this void. This practical handbook fully explains the essentials of this state-of-the-art technique to radiologists, gastroenterologists, radiology residents, and technologists. Major concepts are reinforced by clear, true-to-life illustrations. Readers will find that the practical design and current content of this guide make it an essential introduction to CT colonography.
Fundamentals of treatment planning : Guidelines on how to develop, plan, write, and deliver a prosthodontic care project
Helps dentists, prosthodontists, and students form and organize their thinking and formulate correct diagnoses and therapies that start with appropriate treatment planning
Fundamentals of strategy
Fundamentals of Strategy, is an easy-to-follow guide surrounding the foundational issues of strategy
Fundamentals of Protein NMR Spectroscopy
NMR spectroscopy has proven to be a powerful technique to study the structure and dynamics of biological macromolecules. Fundamentals of Protein NMR Spectroscopy is a comprehensive textbook that guides the reader from a basic understanding of the phenomenological properties of magnetic resonance to the application and interpretation of modern multi-dimensional NMR experiments on 15N/13C-labeled proteins. Beginning with elementary quantum mechanics, a set of practical rules is presented and used to describe many commonly employed multi-dimensional, multi-nuclear NMR pulse sequences. A modular analysis of NMR pulse sequence building blocks also provides a basis for understanding and developing novel pulse programs.
Fundamentals of Nuclear Medicine Dosimetry
This text is a practical introduction that guides the reader through fundamental concepts in the calculation of radiation dose, including discussions of standardized models, methods of calculations, and available software applications. This comprehensive guide discusses the biological effects of radiation on living systems.
Fundamentals of manufacturing engineering using digital visualization
Offers a guide to core principles and practices of manufacturing engineering. It covers the design of, together with technological and measurement issues for, technical systems. Locating charts and setup schemes describing different machining processes are included. Concepts of product quality, with a focus on accuracy indicators, machining accuracy, roughness, and the impact of surface quality on exploitation properties are also explained. Furthermore, key machining methods, including turning, milling, hole machining, grinding, and gear machining, are analyzed in depth, covering their principles, applications, and techniques. The book is enriched by QR codes, linking to a mobile application presenting additional information about the content, for an interactive and extended learning experience. It also uses illustrations visualized with digital tools to promote a better understanding of the concepts.
Fundamentals of Geriatric Medicine : A Case-Based Approach
This handbook addresses the complexity of disease prevention and presentation in elderly patients, as well as geriatric pharmacology. Medicare and Medicaid, and conditions common to elderly patients, including depression, dementia, and hypertension, are also covered. Numerous graphs and tables are included throughout the book to assist the reader in processing the information presented and incorporating it into clinical practice. This practical guide is an essential resource for all those caring for the elderly.
Fundamentals of drug delivery
A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems. Provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery.
Fundamentals of craniofacial malformations ; Vol.2 : Treatment principles
Readers will find detailed discussion of the treatment principles for craniosynostoses, orofacial clefts, branchio-oculo-facial syndromes, soft tissue malformations, dysgnathia and rare syndromes. In addition to description of important facets of treatment and the treatment planning process, guidance is offered on diagnosis and disease classification.
Fundamentals of Cancer Prevention ; 2nd ed.
An authoritative work that provides a detailed review of the current status of cancer prevention and control practice and research. This volume is an essential reference guide and tool for primary care physicians, the research community and students.
Fundamentals of Cancer Prevention ; 1st ed.
An authoritative work that provides a detailed review of the current status of practice and research in cancer prevention and control – an essential reference guide and tool for primary care physicians, the research community and students. Written as a collaborative work by the faculty of the nationally-renowned Cancer Prevention and Control Program at the Arizona Cancer Center, this book harnesses the expertise of researchers, investigators and clinicians in cancer prevention and control, to provide insights into this field for the benefit of nonspecialists.
