الصفحة 22
الصفحة 22
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Drug-Induced Oral Complications

Provides detailed information on the prevalence and manifestations of the most important oral complications associated with different drug treatments, focusing especially on recently developed therapies. Among the diverse adverse drug reactions covered are gingival overgrowth, ulcerations, lichenoid reactions, pigmentation, and bullous reactions. The potential direct toxic effects on bone of drugs that prevent bone mass loss, such as bisphosphonates and denosumab, are fully examined, as is the occurrence of spontaneous oral bleeding in patients receiving antithrombotic therapies. Further chapters focus on drug-induced taste disorders and salivary gland disturbances, including xerostomia, swelling, and hypersalivation. The enhanced risk of oral infections when using chemotherapy and biotherapy is addressed, and the closing chapter examines drug-related perioral and facial complications. This book is a collaborative work that brings together clinicians, surgeons, and specialists in drug safety surveillance.

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Drug discovery targeting drug-resistant bacteria

Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included.

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Drug delivery trends ; Vol. 3 : Expectations and realities of multifunctional drug delivery systems

Examines a drift in the pharmaceutical field across the wide range of dosage forms, drug delivery systems (micro and nanoparticulate), at the regulatory front and on new types of therapies in the market. This book covers the challenges on drug delivery systems in terms of preclinical and current ways of determining quality and the options to solve the challenges associated with this. Most small-medium scale industries and academics struggle with initial regulatory challenges so a detailed discussion on regulatory trend covers the necessary basic understanding of regulatory procedures and provides the required guidance.

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Drug delivery systems using quantum computing

Drug delivery systems (DDS) are defined as methods by which drugs are delivered to desired tissues, organs, cells, and subcellular organs for drug release and absorption through a variety of drug carriers. By controlling the precise level and/or location of a given drug in the body, side effects are reduced, doses are lowered, and new therapies are possible. Nevertheless, there are still significant obstacles to delivering certain medications to particular cells. Drug delivery methods change pharmacokinetic, pharmacodynamic, and drug release patterns to enhance product efficacy and safety, as well as patient convenience and compliance.

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Drug Addiction : From Basic Research to Therapy

Drug Addiction: From Basic Research to Therapy provides a comprehensive overview of physiological, biochemical, genetic and behavioral pathways underlying drug addiction. Focusing on fundamental neurophysiological processes that overlap between drug addiction and other CNS disorders, this volume covers the translation of basic research into novel therapies, not only of drug addiction but a spectrum of related CNS disorders, including pain. Chapters are written by leading scientists with widely ranging expertise in synthetic and computational chemistry, molecular biology, genetics, neurosciences, drug discovery and development, drug targeting, and quantitative therapeutics, providing an unprecedented overview of a complex field of high societal signficance.

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DNA manipulation and analysis

Details technologies on recombinant DNA and nucleic acid manipulation that underpin much of the biological sciences and instructions on how to conduct them successfully. Chapters guide the reader through the basics of oligonucleotide synthesis and DNA sequencing; recombinant DNA plasmid work; cell-free experiments and the latest developments in CRISPR approaches to genome modification.

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Divorce in Europe : New Insights in Trends, Causes and Consequences of Relation Break-ups

This book collects the major discussions in divorce research in Europe. It starts with an understanding of divorce trends. Why was divorce increasing so rapidly throughout the US and Europe and do we see signs of a turn? Do cohabitation breakups influence divorce trends or is there a renewed stability on the partner market?

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Dissemination of information in communication networks : Broadcasting, gossiping, leader election, and fault-tolerance

Preface Due to the development of hardware technologies (such as VLSI) in the early 1980s, the interest in parallel and distributive computing has been rapidly growingandinthelate1980sthestudyofparallelalgorithmsandarchitectures became one of the main topics in computer science. To bring the topic to educatorsandstudents,severalbooksonparallelcomputingwerewritten. The involvedtextbook“IntroductiontoParallelAlgorithmsandArchitectures”by F. Thomson Leighton in 1992 was one of the milestones in the development of parallel architectures and parallel algorithms. But in the last decade or so the main interest in parallel and distributive computing moved from the design of parallel algorithms and expensive parallel computers to the new distributive reality – the world of interconnected computers that cooperate (often asynchronously) in order to solve di?erent tasks.

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Dissecting the Criminal Corpse : Staging Post-Execution Punishment in Early Modern England

Those convicted of homicide were hanged on the public gallows before being dissected under the Murder Act in Georgian England. Yet, from 1752, whether criminals actually died on the hanging tree or in the dissection room remained a medical mystery in early modern society. Dissecting the Criminal Corpse takes issue with the historical cliché of corpses dangling from the hangman’s rope in crime studies. Some convicted murderers did survive execution in early modern England. Establishing medical death in the heart-lungs-brain was a physical enigma. Criminals had large bullnecks, strong willpowers, and hearty survival instincts. Extreme hypothermia often disguised coma in a prisoner hanged in the winter cold. The youngest and fittest were capable of reviving on the dissection table. Many died under the lancet. Capital legislation disguised a complex medical choreography that surgeons staged. They broke the Hippocratic Oath by executing the Dangerous Dead across England from 1752 until 1832.

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Disinfection of root canal systems : The Ttreatment of apical periodontitis

An evidence-based manual that describes root canal anatomy, the endodontic biofilm, and the role of disinfection before presenting the most up-to-date methods of irrigation and disinfection. Individual chapters are devoted to each method, such as positive pressure irrigation, apical negative pressure irrigation, sonic activation, photodynamic therapy, laser technology, and ozonization and electrochemical activation. Clinical photographs throughout show proper irrigation and disinfection techniques.

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Diseases of the Abdomen and Pelvis 2018-2021 : Diagnostic Imaging - IDKD Book

This open access book deals with imaging of the abdomen and pelvis, an area that has seen considerable advances over the past several years, driven by clinical as well as technological developments. The respective chapters, written by internationally respected experts in their fields, focus on imaging diagnosis and interventional therapies in abdominal and pelvic disease; they cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, and positron emission tomography. As such, the book offers a comprehensive review of the state of the art in imaging of the abdomen and pelvis. It will be of interest to general radiologists, radiology residents, interventional radiologists, and clinicians from other specialties who want to update their knowledge in this area.

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Diseases of the abdomen and Pelvis : Diagnostic Imaging and Interventional Techniques

This volume is a collection of chapters dealing with imaging diagnosis and interventional therapies in abdominal and pelvic disease. The different topics are disease-oriented and encompass all the relevant imaging modalities including X-ray technology, nuclear medicine, ultrasound and magnetic resonance, as well as image-guided interventional techniques.

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Discrete Differential Geometry

Discrete differential geometry is an active mathematical terrain where differential geometry and discrete geometry meet and interact. It provides discrete equivalents of the geometric notions and methods of differential geometry, such as notions of curvature and integrability for polyhedral surfaces. Current progress in this field is to a large extent stimulated by its relevance for computer graphics and mathematical physics. This collection of essays, which documents the main lectures of the 2004 Oberwolfach Seminar on the topic, as well as a number of additional contributions by key participants, gives a lively, multi-facetted introduction to this emerging field.

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Discovering Mathematics with Magma : Reducing the Abstract to the Concrete

This volume celebrates the first decade of the Computer Algebra system Magma. With a design based on the ontology and semantics of algebra, Magma enables users to rapidly formulate and perform calculations in the more abstract parts of mathematics. The book range over much of Magma's coverage of algorithmic algebra: from number theory and algebraic geometry, via representation theory and group theory to some branches of discrete mathematics and graph theory. A basic introduction to the Magma language is given in an appendix. The book is simultaneously an invitation to learn a new programming language in the context of contemporary research problems, and an exposition of the types of problem that can be investigated using computational algebra.

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DiPiro’s pharmacotherapy : A pathophysiologic approach

It is this in-depth knowledge of pharmacotherapy, combined with the clinical experience gained through postgraduate training in direct patient care practice, that allows the pharmacist to be the "medication therapy expert" on the healthcare team and to proactively address medication-related problems.It is provides knowledge necessary to prevent, identify, and manage disease and medication-related problems

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Dipeptidyl Aminopeptidases : Basic Science and Clinical Applications

Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses, and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes. Leading experts in the field will contribute to this book, which will present a state-of-the-art view on these enzymes at a time when our understanding of their function is growing ever more rapidly and therapeutic options have become imminent. The sections of the book will focus on various topics including DP IV and related enzymes in: expression and function, metabolic disorders, immune mechanisms and immune disorders, neuronal diseases and cancer, and related drug development.

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Digital Restorative Dentistry : A Guide to Materials, Equipment, and Clinical Procedures

Offers up-to-date, readily understandable guidance on the materials and equipment employed in digital restorative dentistry and on the specific clinical procedures that may be performed using the new technologies. The key components of digital restorative dentistry – image acquisition, prosthetic/restorative design, and fabrication – are fully addressed. Readers will find helpful information on scanners, the software for prosthetic design, and the materials and technologies for prosthesis fabrication, including laser sintering, 3D printing, CAD/CAM, and laser ablation. The section on clinical procedures explains all aspects of the use of digital technologies in the treatment of patients requiring removable partial dentures, complete dentures, fixed partial prostheses, crowns, endodontics, and implant surgery and prosthodontics. The field of restorative and prosthetic dentistry is undergoing rapid transition as these new technologies come to play an increasingly central role in everyday dental practice. In bridging the knowledge gap that this technological revolution has created in the field of dentistry, the book will satisfy the needs of both dentists and dental students.

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Digital Integration, Growth and Rational Regulation

This book focuses on the role of information and communication technologies for economic integration, networking and growth. Technological and regulatory dynamics are highlighted with respect to EU countries and the US. The analysis deals with the main issues of rational regulations in open economies. Schumpeterian developments and dynamic efficiency gains are crucial for Europe in the context of telecommunications competition and network modernisation – achieving the goals of the Lisbon Agenda requires adequate incentives for investment and solid capital market prospects. Economic progress in the digital knowledge society will be characterised by enormous structural change and the growth of digital services. New policy conclusions at both the national and international levels – including welfare analysis – are presented.

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Digital Fluency : Understanding the Basics of Artificial Intelligence, Blockchain Technology, Quantum Computing, and Their Applications for Digital Transformation

If you are curious about the basics of artificial intelligence, blockchain technology, and quantum computing as key enablers for digital transformation, Digital Fluency is your handy guide. The real-world applications of these cutting-edge technologies are expanding rapidly, and your daily life will continue to be affected by each of them. There is no better time than now to get started and become digitally fluent.

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