الصفحة 21
الصفحة 21
Cardiac gene therapy : Methods and protocols
Discussions on topics such as gene suppression, editing, and reprogramming; cardiac gene therapy vectors and promoters; cardiac gene delivery methods; pulmonary hypertension; and patient screening and measuring the efficacy of cardiac gene therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Carcinoma della cervice uterina : Eziopatogenesi e profilassi = Carcinoma of the uterine cervix : Aetiopathogenesis and prophylaxis
The volume offers a synthetic and updated picture of a complex topic that includes the multifactorial etiopathogenesis of cervical cancer, the characteristics of the virus, the dynamics of HPV infections, the histological lesions of the cervix leading to cervical cancer. and the characteristics of the various surgical treatments, the current strategies for early diagnosis through the use of molecular assays currently on the market, up to the trials of the two vaccines recently registered also in Italy.
Cancer Proteomics : From Bench to Bedside
the authors collectively provide the current status of proteomics in cancer therapy and offers the existing technologies used in proteomics that allow for protein profiling and for the identification of druggable targets in human samples. Mass spectrometry based protein characterization and protein microarrays hold great promise of predicting response to specific drugs in cancer therapy. Insightful to the reader with broad perspectives on topics related to the use of proteomic strategies in cancer therapy, Cancer Proteomics offers anticipated challenges that may arise from its application in daily practice.
Can We Talk? : Seven Principles for Managing Difficult Conversations at Work
This book offers guidance on how to create the right conditions for a meaningful discussion. The author identifies the seven key principles that enable both parties to gain a deeper understanding of what the other person may be thinking and will help establish their point of view more clearly: confidence, clarity, compassion, curiosity, compromise, credibility, courage.
Campbell biology; 12th ed.
Delivers a trusted, accurate, current, and pedagogically innovative experience that guides students to a true understanding of biology. The author team advances Neil Campbell's vision of meeting and equipping students at their individual skill levels by developing tools, visuals, resources, and activities that encourage participation and engage students in their learning. Known for strategically integrating text and artwork, this trusted course solution works hand in hand with Mastering Biology to reinforce key concepts, build scientific skills, and promote active learning.
Business Plan: Telepherique Du Bludan
Telepherique Du Bludan is one of the most prominent tourist attractions that targets tourists and visitors from all over the world and it’s a unique and unconventional experience. Bludan area has a strategic location and we should give it more spotlights since it has a wonderful weather in the winter and in the summer, In order to stimulate domestic tourism, we have implemented a project to construct a cable car in the Bludan area in an entertainment complex, and this is something that does not exist in Syria and encourages tourism in the winter to transport people to heights for the possibility of enjoying snow and practicing snow activities, and in summer it can be used to transport people to the top of the height and get a beautiful view in great weather And enjoyment in outdoor activities that are not found in Syria, and this adds a competitive advantage to our project.
Business Education and Emerging Market Economies : Perspectives and Best Practices
Business Education in Emerging Market Economies discusses the impact of business education on emerging markets and explores curricular innovation, pedagogical approaches, and strategic alliances in the context of industrializing economies. Emerging markets consist of eighty percent of the world's population and some 75% of its trade growth in the foreseeable future according to the U.S. Department of Commerce. The potential economic growth of emerging markets has prompted a need to understand the dynamics of these markets, their business institutions, and their educational systems. The pressures of globalization and the recent economic reforms that swept across emerging, developing, and transitioning, economies have had a positive impact on the demand for business education and business knowledge from the developed and industrialized countries. As a result, many methods were developed to transfer know-how from the developed markets including learning through imitation, using western style pedagogical approaches, attending universities in industrialized countries, learning through experience and practice, and using information technology. The conclusion we reach is that business and management education in emerging markets is fast changing the way in which these markets operate and are perceived – business educators are catalysts for greater economic integration.
Business agility and information technology diffusion ; IFIP TC8 WG 8.6 International working Conference, May 8-11, 2005, Atlanta, Georgia, USA
Addresses issues related to business agility and the diffusion of Information Technology (IT). Success, even survival, in today's business environment has been made complex and difficult by technologically-based competitive pressure. One promising strategy is to be agile and ready to adapt quickly to changes in the environment or market. Such strategy takes shape as an agile software development, agile manufacturing, agile modeling and agile iterations. In contrast, successful IT diffusion is known to be a process that takes time and careful effort. Many IT projects that succeeded in developing a product have subsequently failed in changing the behavior of the target group when diffusion just didn't happen. Therefore this volume responds to the question: What is the relationship between agility and IT diffusion? The book's scope will cover information systems and technology issues, as well as organizational and managerial issues, related to agility and IT diffusion. The planned perspectives include topics such as diffusion of agile methods, enabling business agility with IT, creating agile environments that facilitate diffusion of IT, theories and frameworks for understanding diffusion and agility issues, best practices relating to business agility and IT diffusion, software process improvement and agility, diffusion studies of specific agile technologies, and impacts of diffusion of IT agile methods.
Buruli Ulcer : Mycobacterium Ulcerans disease
A major objective of this book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans.
Building systems in interior design
Takes an entirely new approach to teaching this essential topic for Architects, Designers and Building Engineers. Written to prepare students for the real world and packed with practical examples, the book will foster an understanding of specific issues that are critical to those features of technical systems that most directly affect design. The book stresses the ever-present nature of these systems: they are everywhere, all the time. Taking a design oriented view, it outlines what can and cannot be done, and provides the student with the know-how and confidence to defend and promote their design intent when working with other industry professionals.
Brown and Mulholland’s drug calculations
A realistic practice problems and unique "proof" step in the answer key that allows you to double-check your answers to avoid medication errors. This edition continues to promote critical thinking, clinical judgment, and patient safety with respect to accurate drug dosages. Helpful worksheets, assessment tests, and Clinical Alerts call attention to situations in actual practice that have resulted in drug errors — giving you extensive hands-on practice for the Next Generation NCLEX® and beyond.
Bringing Pain Relief to Children : Treatment Approaches
In Bringing Pain Relief to Children: Treatment Approaches, a panel of prominent clinician-scientists comprehensively reviews the latest developments in pediatric pain management, with special emphasis on the setting in which pain is detected and managed. The authors explore the cutting-edge of children's pain care in inpatient, outpatient, palliative care, school, and residential settings, and describe alternate approaches, including complementary and alternative medicine, pain management via the internet and information technology, and pain care in developing countries.
Brilliant light in life and material sciences
This book aim to create a synchrotron radiation facility, CANDLE, as an international laboratory for advanced research in life and material sciences. About 50 researchers from NATO, partner countries and Armenia gathered at Yerevan to discuss modern trends in developments of advanced light sources with high spectral brilliance and applications in basic and applied research in a wide range of fields. Research with high brilliant photon beams are used, for example for practical applications in pharmacy, electronics and nanotechnology. Such practical relevance promoted the design and construction of now more than 50 such facilities worldwide. Overview and specialized talks on the status and highlights of newly constructed light sources (ALBA, SPEAR3, European XFEL Facility, Siberian Synchrotron Radiation Center, CANDLE), on instrumentation and development of experimental techniques, and frontier research in life and material sciences using synchrotron radiation have been presented.
Body Sensor Networks
While the problems of long-term stability and biocompatibility are being addressed, several promising prototypes are starting to emerge for managing patients with acute diabetes, for treatment of epilepsy and other debilitating neurological disorders and for monitoring of patients with chronic cardiac diseases. Despite the technological developments in sensing and monitoring devices, issues related to system integration, sensor miniaturization, low-power sensor interface circuitry design, wireless telemetric links and signal processing still have to be investigated.
Bioremediation of Soils Contaminated with Aromatic Compounds
Environmental biotechnology, which was in its infancy in the early 80's, has evolved thanks to the revolution brought about by molecular biology. Multiple successes in the biological cleanup of civil and industrial wastewater and of hydrocarbon soil pollution, demonstrate the vast power of clean technologies. In addition, the buildup of information on the activities of microorganisms as catalysts in all sorts of natural, industrial and animal environments has flourished. There is a continuing realization of the critical role of microbial processes in biological, industrial and geological systems. Since environmental biotechnology has matured, it is ready to tackle bigger challenges: the scaling up of many bioremediation systems still in progress, the search for novel biocatalysts for industrial applications, the continuing effort against common human life-threatening processes such as antibiotic resistance, the accumulation of hormone-mimicking substances (endocrine disrupters), the deposition of air-borne pesticides in the environment and, the degradation of recalcitrant contaminants. These endeavors will help prevent the contamination of food chains, protect human life and allow for human activity and economic development that do not compromise environmental sustainabijity.
BioPaceMaking
The development of a bio-engineered pacemaker is of substantial clinical and also scientific interest because it promises to overcome several limitations of electronic pacemakers. Moreover it may answer the longstanding question of whether the complex structure of the sinus node is indeed a prerequisite for reliable pacemaking, or simpler structures might work as well. This book gives an overview of the current state-of-the-art of creating a bio-engineered pacemaker. It shows the approaches to develop of genetic and cell-based engineering methods suitable to implement them with safety and stability. It also illuminates the problems that need to be solved before bio-pacemaking can be considered for clinical use.
Biomarkers in periodontal health and disease : Rationale, benefits, and Future directions
This book examines all aspects of the progress being made towards the development of highly specific and sensitive biomarkers that will overcome the shortcomings of clinical assessments in periodontics. Readers will find the book to be an ideal summary of the state of the art in the field as biomarkers emerge that promise to facilitate periodontal diagnostics and permit timely, personally tailored interventions.
Biologics in General Medicine
The idea for this book was born during the symposium on biologics organized by ZAFES (Center for Drug Research, Development and Safety at the University of Frankfurt am Main) in September 2005. Highly distinguished researchers special- ing in the field of biologics had gathered together to exchange information on this relatively new subject. Realizing that this symposium was one of the few sources of condensed information on biologics, it became obvious that we had to create a means of informing an interested wider circle of scientists and especially general c- nicians. Therefore, the editors of this book suggested to the researchers at the symposium andalsotoprominent scientists andcliniciansinvolvedinthe developmentand application of biologics as their major field of interest the idea of assembling this compendium. We received an overwhelmingly positive response – thankfully also from the publisher – most being more than willing to support this innovative project with highly relevant chapters on the latest state of the art.
Bioinformatics Using Computational Intelligence Paradigms
Bioinformatics as well as Computational Intelligence are undoubtedly remarkably fast growing fields of research and real-world applications with enormous potential for current and future developments. "Bioinformatics using Computational Intelligence Paradigms" contains recent theoretical approaches and guiding applications of biologically inspired information processing systems(Computational Intelligence) against the background of bioinformatics. This carefully edited monograph combines the latest results of Bioinformatics and Computational Intelligence and offers a promising cross-fertilisation and interdisciplinary work between these growing fields.
Bioinformatics of genome regulation and structure II
The conference was organized by the Laboratory of Theoretical Genetics, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia. The material covers the most recent topics in bioinformatics, including (i) regulatory genomic sequences: databases, knowledge bases, computer analysis, modeling, and recognition; (ii) large-scale genome analysis and functional annotation; (iii) gene structure detection and prediction; (iv) comparative and evolutionary genomics; (v) computer analysis of genome polymorphism and evolution; computer analysis and modeling of transcription, splicing, and translation; structural computational biology: structure- function organization of genomic DNA, RNA, and proteins; (vi) gene networks, signal transduction pathways, and genetically controlled metabolic pathways: databases, knowledge bases, computer analysis, and modeling; principles of organization, operation, and evolution; (vii) data warehousing, knowledge discovery and data mining; and (viii) analysis of basic patterns of genome operation, organization, and evolution.
