الصفحة 21
الصفحة 21
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Machine learning for biomedical application

Biomedicine is a multidisciplinary branch of medical science that consists of many scientific disciplines, e.g., biology, biotechnology, bioinformatics, and genetics; moreover, it covers various medical specialties. In recent years, this field of science has developed rapidly. This means that a large amount of data has been generated, due to (among other reasons) the processing, analysis, and recognition of a wide range of biomedical signals and images obtained through increasingly advanced medical imaging devices. The analysis of these data requires the use of advanced IT methods, which include those related to the use of artificial intelligence, and in particular machine learning. It is a summary of the Special Issue “Machine Learning for Biomedical Application”, briefly outlining selected applications of machine learning in the processing, analysis, and recognition of biomedical data, mostly regarding biosignals and medical images.

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Machine Learning and Probabilistic Graphical Models for Decision Support Systems

Presents recent advancements in research, a review of new methods and techniques, and applications in decision support systems (DSS) with Machine Learning and Probabilistic Graphical Models, which are very effective techniques in gaining knowledge from Big Data and in interpreting decisions. It explores Bayesian network learning, Control Chart, Reinforcement Learning for multicriteria DSS, Anomaly Detection in Smart Manufacturing with Federated Learning, DSS in healthcare, DSS for supply chain management, etc. Researchers and practitioners alike will benefit from this book to enhance the understanding of machine learning, Probabilistic Graphical Models, and their uses in DSS in the context of decision making with uncertainty. The real-world case studies in various fields with guidance and recommendations for the practical applications of these studies are introduced in each chapter.

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Lysosomal Storage Disorders

This book is dedicated to patients affected by Lysosomal Storage Disorders, and especially to the National Gaucher Foundation (USA) and the Colombian Association of Patients with Lysosomal Storage Diseases (ACOPEL for its Spanish Acronym). Both organizations will share in the sales of this book.

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Low-Dose Radiation Effects on Animals and Ecosystems : Long-Term Study on the Fukushima Nuclear Accident

Brings together the works of radiation biologists and ecologists to provide reliable radioecology data and gives insight into future radioprotection. The book examines the environmental pollution and radiation exposure, and contains valuable data from abandoned livestock in the ex-evacuation zone and from wild animals including invertebrates and vertebrates, aqueous and terrestrial animals, and plants that are subjected to long-term exposure in the area still affected by radiation. It also analyzes dose evaluation, and offers new perspectives gained from the accident, as well as an overview for future studies to promote radioprotection of humans and the ecosystem.

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Lotus japonicus Handbook

Represents the first effort to compile basic descriptions and methods for research in Lotus, including symbiotic processes, cell and molecular biology protocols, functional genomics, mutants, gene tagging and genetic analysis, transformation and reverse genetic analysis, primary and secondary metabolism, and an exhaustive update of the scientific literature available on this plant.

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Logos of phenomenology and phenomenology of the logos ; Book Two : The Human Condition in-the-Unity-of-Everything-there-is-alive Individuation, Self, Person, Self-determination, Freedom, Necessity

The Human Condition-in-the-unity-of-everything-there-is-alive, under whose aegis the present selection of essays falls, offers the urgently needed new approach to reinvestigating humanness. While recent advances in the neurosciences, genetics and bio-engineering challenge the traditional abstract conception of "human nature", indicating its transformability, thus putting in question the main tenets of traditional philosophical anthropology, in the new perspective of the Human Creative Condition the human individual is seen in its emergence and unfolding within the dynamic networks of the logos of life, and within the evolution of living types.

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Liver Immunology : Principles and Practice

parasitic and viral infections of the liver, autoimmune liver disease, alcoholic and nonalcoholic fatty liver diseases, and transplantation in an easy-to-read and thorough format. Authors also address the key issues that have arisen in this field in recent years, including physiological roles of hepatocytes, sinusoidal lining cells, activated macrophages (Kupffer cells), cholangiocytes and stellate cells, and their modulation of T cells, natural killer (NK) cells and NKT cells.

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Linkage in Evolutionary Computation

The whole volume consisting of 19 chapters is divided into 3 parts: Models and Theories; Operators and Frameworks; Applications. This edited volume will serve as a useful guide and reference for researchers who are currently working in the area of linkage. For postgraduate research students, this volume will serve as a good source of reference. It is also suitable as a text for a graduate level course focusing on linkage issues.

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Linear Selection Indices in Modern Plant Breeding

This open access book focuses on the linear selection index (LSI) theory and its statistical properties. It addresses the single-stage LSI theory by assuming that economic weights are fixed and known - or fixed, but unknown - to predict the net genetic merit in the phenotypic, marker and genomic context. Further, it shows how to combine the LSI theory with the independent culling method to develop the multistage selection index theory. The final two chapters present simulation results and SAS and R codes, respectively, to estimate the parameters and make selections using some of the LSIs described. It is essential reading for plant quantitative geneticists, but is also a valuable resource for animal breeders.

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Linear Genetic Programming

Linear Genetic Programming examines the evolution of imperative computer programs written as linear sequences of instructions. In contrast to functional expressions or syntax trees used in traditional Genetic Programming (GP), Linear Genetic Programming (LGP) employs a linear program structure as genetic material whose primary characteristics are exploited to achieve acceleration of both execution time and evolutionary progress.

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Linear and Generalized Linear Mixed Models and Their Applications

This book covers two major classes of mixed effects models—linear mixed models and generalized linear mixed models—and it presents an up-to-date account of theory and methods in analysis of these models as well as their applications in various fields. It offers a systematic approach to inference about non-Gaussian linear mixed models. Furthermore, it discusses the latest developments and methods in the field, incorporating relevant updates since publication of the first edition. These include advances in high-dimensional linear mixed models in genome-wide association studies (GWAS), advances in inference about generalized linear mixed models with crossed random effects, new methods in mixed model prediction, mixed model selection, and mixed model diagnostics.

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Lindhe's Clinical Periodontology and Implant Dentistry ; 2 Vol. Set ; 7th ed.

Provides an introduction to anatomy, including periodontal tissues, the edentulous ridge, the mucosa at teeth and implants, and osseointegration Discusses the epidemiology of periodontal and peri-implant diseases Explores the microbiology, including dental biofilms and calculus, periodontal infections, peri-implant infections, the pathogenesis of gingivitis and periodontitis, and the genetic susceptibility to periodontal disease Includes the latest perio- and peri-implant disease classifications Contains updated evidence-based preventive and treatment modalities for the treatment of periodontal and peri-implant diseases Features the latest evidence-based therapeutic alternatives on the use of dental implants to rehabilitate the lost dentition

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Lessons Learned : Risk Management Issues in Genetic Counseling

The only book devoted exclusively to this specialty, Lessons Learned details the risk management issues involved in genetic counseling practice, and offers solid strategies for minimizing the risk of costly, career-damaging malpractice suits. Schmerler clearly identifies areas of practitioner liability and demonstrates how they may be averted, so counselors can better manage their practice while lowering the risk of legal action. Examples drawn from relevant court cases illustrate typical issues in malpractice, negligence, and breach of contract suits. With this in-depth knowledge, readers can refine their goals toward increased self-protection as well as client care.

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Les cancers ovariens = Ovarian cancers

Deals with ovarian cancers and their therapeutic management. Besides the epithelial tumors which are the most frequent, the rarer tumors, with attenuated malignancy, germ cells or of the ovarian stroma are also studied. Specialists from multiple backgrounds each deliver in their field the most recent knowledge on the fundamental aspects of the disease, its genetic, epidemiological and prognostic characteristics and its pathological peculiarities. Modern means of diagnosis are presented. The surgical technique, including laparoscopy, is detailed at the different stages of the disease. The therapeutic strategy aims to position the surgery and chemotherapy according to the stage. The current place of radiotherapy and isotopic therapies is indicated. Some more specific aspects are discussed, screening, lymph node dissection, the “second look”, intraperitoneal chemotherapy with or without hyperthermia, treatment of the elderly, monitoring after treatment… as well as the emergence of targeted therapies.

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Les cancers digestifs = Digestive cancers

Digestive tumors are among the most common malignant tumors and represent a major public health problem. This is one of the areas that has evolved the most in recent years in oncology due to significant progress in diagnostic strategies and therapeutic management. It seems essential that this progress be implemented in the daily practice of physicians treating these tumors. This book, the result of multidisciplinary work, provides a practical and up-to-date approach to the management of malignant digestive tumors. The first chapters are devoted to general and original subjects such as epidemiology, genetics, the management of elderly subjects. A second part approaches in a pragmatic and practical way the principles of diagnostic and therapeutic management by localization. A third part, devoted to the practical realization of chemotherapy, takes stock of new therapeutic approaches, oral or locoregional chemotherapy. Finally, the last part of the book is dedicated to digestive cancer emergencies and the palliative management of these tumors.

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Lentil : An ancient crop for modern times

Presents the most comprehensive and up to date review of research on lentil production systems, biotic and abiotic stresses management, quality seed production, storage techniques and lentil growing around the world. This book will be of great value to legume breeders, scientists, nutritionists, academic

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Lehninger Principles of Biochemistry

Help students navigate the complex discipline of biochemistry with a clear and coherent presentation. Renowned authors David Nelson, Michael Cox, and new co-author Aaron Hoskins have focused this eighth edition around the fundamental principles to help students understand and navigate the most important aspects of biochemistry. Text features and digital resources in the new Achieve platform emphasize this focus on the principles, while coverage of recent discoveries and the most up-to-date research provide fascinating context for learning the dynamic discipline of biochemistry.

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Left-right asymmetry in vertebrate development

A host of studies has unravelled the involvement of many genes in the left right patterning pathway. Based on this knowledge the genetic basis of human laterality defects are beginning to be revealed. It is a major challenge now to understand how all these genes control left right development as well as the complex set of interactions established between them.

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Learning Classifier Systems ; International Workshops, IWLCS 2003-2005, Revised Selected Papers

The work embodied in this volume was presented across three consecutive e- tions of the International Workshop on Learning Classi?er Systems that took place in Chicago (2003), Seattle (2004), and Washington (2005). The Genetic and Evolutionary Computation Conference, the main ACM SIGEvo conference, hosted these three editions.

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Learning Classifier Systems ; 10th International Workshop, IWLCS 2006, Seattle, MA, USA, July 8, 2006 and 11th International Workshop, IWLCS 2007, London, UK, July 8, 2007, Revised Selected Papers

Constitutes the thoroughly refereed joint post-conference proceedings of two consecutive International Workshops on Learning Classifier Systems that took place in Seattle, WA, USA in July 2006, and in London, UK, in July 2007 - all hosted by the Genetic and Evolutionary Computation Conference, GECCO.The 14 revised full papers presented were carefully reviewed and selected from the workshop contributions. The papers are organized in topical sections on knowledge representation, analysis of the system, mechanisms, new directions, as well as applications.

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