الصفحة 209
الصفحة 209
Equitable research partnerships : A global code of conduct to counter ethics dumping
This book offers insights into the development of the ground-breaking Global Code of Conduct for Research in Resource-Poor Settings (GCC) and the San Code of Research Ethics. Using a new, intuitive moral framework predicated on fairness, respect, care and honesty, both codes target ethics dumping – the export of unethical research practices from a high-income setting to a lower- or middle-income setting. The book is a rich resource of information and argument for any research stakeholder who opposes double standards in research. It will be indispensable for applicants to European Union framework programmes, as the GCC is now a mandatory reference document for EU funding.
Equilibrium Between Phases of Matter : Phenomenology and Thermodynamics
The phase behaviour of materials and their thermodynamic properties are a central subject in all fields of materials research. The first Volume of the work, meant for graduate students in chemistry, geology, physics, and metallurgy, and their engineering counterparts, is split up in three levels, such that from level to level the portion and importance of thermodynamics and mathematics are increased. In the ground level it is shown that the basic principles of phase equilibria can be understood without the use of thermodynamics – be it that the concept of chemical potential is introduced right from the beginning. The intermediate level is an introduction to thermodynamics; culminating in the Gibbs energy as the arbiter for equilibrium – demonstrated for systems where the phases in equilibrium are pure substances. In the third level the accent is on binary systems, where one or more phases are solutions of the components.
Equidosimetry : Ecological Standardization and Equidosimetry for Radioecology and Environmental Ecology
Considerable experience with radioecological and related ecological research on terrestrial and aquatic ecosystems has been achieved, especially after the Chernobyl accident. The combined effects of the radiation, chemical and biological factors, after a contamination of the environment and during its remediation have shown an interactive complexity that highlights the need for equidosimetrical evaluations of the influence of the various stressors and the need for their ecological normalization. In radioecology and radiation protection, methods of radiation dosimetry are key for dose assessment. It is therefore highly desirable to develop a clear theoretical approach as well as a practical method of equidosimetry that would allow for an ecological normalization of the different stressors in unified uniform units, especially for comparison purposes.
Equidistribution in Number Theory, An Introduction
This volume presents details of the lecture series that were given at the school. Across the broad panorama of topics that constitute modern number t- ory one nds shifts of attention and focus as more is understood and better questions are formulated. Over the last decade or so we have noticed incre- ing interest being paid to distribution problems, whether of rational points, of zeros of zeta functions, of eigenvalues, etc. Although these problems have been motivated from very di?erent perspectives, one nds that there is much in common, and presumably it is healthy to try to view such questions as part of a bigger subject.
Equazioni a derivate parzial I : Complementi ed esercizi
La presente raccolta di problemi ed esercizi nasce dall'esperienza maturata durante il corso di Equazioni a Derivate Parziali (EDP), tenuto nell'ambito delle lauree di primo e secondo livello presso il Politecnico di Milano. Il volume è diviso in due parti; nei primi quattro capitoli l'obiettivo è l'uso di tecniche classiche, come la separazione delle variabili, il principio di massimo o le trasformate di Laplace e Fourier, per risolvere problemi di diffusione, trasporto e vibrazione. Il quinto capitolo invita a familiarizzare con i risultati di base negli spazi di Hilbert, nella teoria delle distribuzioni (o funzioni generalizzate) di Schwartz e in quella degli spazi di Sobolev più comuni. Il sesto ed ultimo capitolo riguarda la formulazione variazionale o debole dei più importanti problemi iniziali e/o al bordo per equazioni ellittiche e di evoluzione. L'introduzione ad ogni capitolo contiene una sintesi degli strumenti teorici più utilizzati.
Epiphyseal Growth Plate Fractures
This comprehensive reference work covers all aspects of growth plate fractures and their complications. Following general reviews of growth plate fractures, 21 chapters deal with each epiphyseal growth plate in the body. All of these chapters are constructed similarly for easy and quick retrieval of the required information. The main emphasis is on evaluation (diagnosis) and management (treatment). A separate section is devoted to premature partial physeal arrest, as this is by far the most common and feared complication of a growth plate fracture and its treatment is involved and controversial. The case studies included are often based on 20- to 30-year follow-ups, revealing cases that originally appeared to be quite satisfactory at the conclusion of growth but were found to have turned out quite poorly years later.
Epilepsy
Epilepsy has remained a significant social concern and financial burden globally. It is the most common neurological disease of the brain. Around 1% of the people worldwide have epilepsy and this disease affects people of all ages, Although the different types of epilepsy vary greatly, medication appropriate can control seizures in about 70% of patients, Medications are mainstays in controlling epileptic seizures, Partial seizures, which are the most common seizure type in adults, can be effectively controlled by virtually all the standard and newer antiepileptic drugs (AEDs). For the generalized epilepsies, valproate remains the drug of choice.
Epigenetics in oncology
Covers the most recent advances in RNA/histone/DNA epigenetics in Oncology. RNA/histone/DNA epigenetics have been shown to play pivotal roles in cancer initiation, progression, maintenance and drug response/resistance, tumor microenvironment, cancer stem cell self-renewal, cancer metabolism, and tumor immune evasion. In particular, research in RNA cancer epigenetics has made impressive progress in the last few years. Individual chapters in Part I (focusing on RNA epigenetics) are devoted to RNA modifications in Cancer Metabolism and Microenvironment, Cancer Stem Cell Biology, Immune Surveillance, Solid Tumors and Tumor Immunity, and Hematopoietic Malignancies, as well as to RNA editing in Cancer. Chapters in Part II and III of the book focus on histone epigenetics and DNA epigenetics, respectively.
Epigenetic Drug Discovery
This broad view of epigenetic approaches in drug discovery combines methods and strategies with individual targets, including new and largely unexplored ones such as sirtuins and methyl-lysine reader proteins. Presented in three parts - Introduction to Epigenetics, General Aspects and Methodologies, and Epigenetic Target Classes - it covers everything any drug researcher would need in order to know about targeting epigenetic mechanisms of disease.
Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives
The book covers enzymatic (including chemo-enzymatic) methods, with a focus on the synthesis and incorporation of modified nucleosides. The authors also offer a review of innovative approaches for the non-enzymatic chemical synthesis of nucleic acids and their analogs and derivatives, highlighting especially challenging species. The book offers a concise review of the methods that prepare novel and heavily modified polynucleotides in sufficient amount and purity for most clinical and research applications.
Environments for Multi-Agent Systems III ; 3rd International Workshop, E4MAS 2006, Hakodate, Japan, May 8, 2006, Selected Revised and Invited Papers
This book are organized in topical sections on models, architecture, and design, mediated interaction and stigmery, governing environment, and applications.
Environments for Multi-Agent Systems II ; 2nd International Workshop, E4MAS 2005, Utrecht, The Netherlands, July 25, 2005, Selected Revised and Invited Papers
This book constitutes the thoroughly refereed post-proceedings of the Second International Workshop on Environments for Multiagent Systems, E4MAS 2005, held in July 2005. The 16 revised papers presented were carefully reviewed and selected from the lectures given at the workshop.
Environments for Multi-Agent Systems ; 1st International Workshop, E4MAS, 2004, New York, NY, July 19, 2004, Revised Selected Papers
The modern ?eld of multiagent systems has developed from two main lines of earlier research. Its practitioners generally regard it as a form of arti?cial intelligence (AI). Some of its earliest work was reported in a series of workshops in the US dating from1980,revealinglyentitled,“DistributedArti?cialIntelligence,”andpioneers often quoted a statement attributed to Nils Nilsson that “all AI is distributed. ” The locus of classical AI was what happens in the head of a single agent, and much MAS research re?ects this heritage with its emphasis on detailed modeling of the mental state and processes of individual agents. From this perspective, intelligenceisultimatelythepurviewofasinglemind,thoughitcanbeampli?ed by appropriate interactions with other minds. These interactions are typically mediated by structured protocols of various sorts, modeled on human conver- tional behavior. But the modern ?eld of MAS was not born of a single parent. A few - searchershavepersistentlyadvocatedideasfromthe?eldofarti?ciallife(ALife). These scientists were impressed by the complex adaptive behaviors of commu- ties of animals (often extremely simple animals, such as insects or even micro- ganisms). The computational models on which they drew were often created by biologists who used them not to solve practical engineering problems but to test their hypotheses about the mechanisms used by natural systems. In the ar- ?cial life model, intelligence need not reside in a single agent, but emerges at the level of the community from the nonlinear interactions among agents. - cause the individual agents are often subcognitive, their interactions cannot be modeled by protocols that presume linguistic competence.
Environmental Security in Harbors and Coastal Areas : Management Using Comparative Risk Assessment and Multi-Criteria Decision Analysis
This book explores the challenges facing coastal areas during the next few decades and the difficult decisions needed to prevent a repeat of the past. Establishing, maintaining or enhancing a sense of environmental security in different coastal regions and improving the management of critical infrastructure will require (i) matching human demands with available environmental resources; (ii) recognition of environmental security threats and infrastructure vulnerabilities; and, (iii) identification of the range of available options for preventing and/or minimizing natural disasters, technological failures, and/or terror actions. This book emphasizes beliefs that the convergence of seemingly disparate viewpoints and often uncertain and limited information is possible only by using one or more available risk assessment methodologies and decision-making tools such as multi-criteria decision analysis (MCDA).
Environmental Security and Sustainable Land Use - with special reference to Central Asia
This book presents important aspects of environmental security and sustainable land use in general and in particular for Central Asia, i.e. the environmental consequences of climate change; sustainable land use and regional development; sustainable development in mountain and steppe regions; beyond borders: Transboundary Biosphere Reserve "Altai" as an approach for regional development; landscape planning as an integrative tool for sustainable development; challenges and threats for environmental stability in Central Asia. A final recommendation in the area of sustainable development and land use as well as the proceeding efforts towards the establishment of the Transboundary Biosphere Reserve "Altai" and the implementation of landscape planning were set in the book as some of the main results of the meeting.
Environmental Security and Public Safety ; Problems and Needs in Conversion Policy and Research after 15 Years of Conversion in Central and Eastern Europe
Although the end of the Cold War has paved the way to a substantial demilitarisation and conversion, the leftovers of this process – such as former military installations, military training areas, and huge quantities of unserviceable ammunition and equipment – still pose a severe threat to the environment of both NATO and Partner countries.The rehabilitation of these areas for civilian uses is extremely costly and is generally in the short and medium term not possible. For this reason, the development of new methods for the estimation avoidance of risks should receive special priority. In the context of this ARW, the reconnaissance and appraisal of conversion areas with respect to costs, returns, and legal considerations were discussed. The decades-long use of some areas led to the heavy loading of contaminates. Every task of conversion has as its goal the elimination of dangers to humans and nature, and the return of areas to civil use, such that these areas can be used realise economic interests of the society.
Environmental security and environmental management : The role of risk assessment ; Proceedings of the NATO Advanced Research Workhop on The Role of Risk Assessment in Environmental Security and Emergency Preparedness in the Mediterranean Region, held in Eilat, Israel, April 15-18, 2004
The concept of “environmental security” has emerged as one basis for understanding international conflicts. This phrase can mean a variety of things. It can signify security issues stemming from environmental concerns or conflicting needs, or it can mean that the environment is treated as a resource for the long term, and the question is what should be done today to preserve the quality of the environment in the future. In the same way that energy security is about ensuring access to energy for the long run, it can also mean that pressing environmental concerns create a situation where different countries and communities are forced to collaboratively design a unified response, even if cooperation is not generally in the logic of their relations. Over the last several years, the authors of this book and their colleagues have tried to demonstrate the power of risk assessment and decision analysis as valuable tools that decision makers should use for a broad range of environmental problems, including environmental security. Risk analysis is almost more a state of mind or a way of looking at problems than it is a kind of algorithm or a set of recipes. It projects a kind of rationality on problems and forces a certain degree of quantitative rigor, as opposed to the all too common tendency of making environmental recommendations based on anecdotal evidence.
Environmental Role of Wetlands in Headwaters
Internationally, the wetlands of headwater and upland regions provide many valuable environmental services. This book moves towards a more comprehensive inventory of the benefits and costs of headwater wetlands. It evaluates the research that tries to understand the tolerances, exchanges, checks and balances within headwater landscapes and the downstream impacts of changes in wetlands. It employs case studies and reviews from 21 nations spanning Europe, Africa, Asia and the Americas. It explores the new policy frameworks, changes in land husbandry, new systems for community education, participatory processes and technological interventions required for the effective management of headwater wetlands and the full integration of wetlands (including newly constructed wetlands) into environmental management and planning. In the past, most research dealt with wetlands as isolated features, this book examines wetlands in their watershed management context.
Environmental Problems of Central Asia and their Economic, Social and Security Impacts
entral Asia is a developing region with great potential, but there are valid concerns that current resource management practices are not sustainable, particularly with regard to the management of water resources. Recent changes in social structures, accompanied by regional climate change, have caused substantial environmental changes leading to security concerns in the region. As a result, the local economy has been significantly impacted to the extent that the potential for social unrest is of great concern.
Environmental Policy Analyses : Learning from the Past for the Future - 25 Years of Research
The criteria used to select the fifteen contributions in this book were their impact on the scientific debate at the time of their publication, their validity for p- sent conceptualizations of policy analysis in the field of the environment, and their contribution to the development of policy analysis as a whole . Moreover, the selected contributions mainly focus on empirical appli- tions in the field of environmental policies or the interface between en- ronmental and non-environmental policies. Some have led to concrete p- icy recommendations of which most have been partly implemented since, This research also sometimes addressed regional political administrative arrangements leading to administrative reforms and new strategic directions of implementing agencies.
