الصفحة 20
الصفحة 20
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Antibacterial effects of Algae

An alarm increase in the rate of emerging of resistance bacteria have been causing a great public concern worldwide. This problem of increasing resistance has necessitated the search for safe and effective factors that may be used to treat persistent bacterial infections or modify the currently available antibiotic. This study deals with the antimicrobial potential assessment of ulva flexuosa , ulva flexuosa was collected from at MAZAR ELKHODER. Crude organic extracts were prepared using methanolic and chloroformic extract and tested against 6 indicator microorganisms using the disk diffusion method and also applied against biofilm ( dental plaque).

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Antiangiogenic Agents in Cancer Therapy

Antiangiogenesis remains a dynamic and evolving field in oncology. New therapeutic targets continue to emerge followed by the rapid development of new therapeutic agents to be investigated in clinical trials. Optimizing the therapeutic potential of antiangiogenic agents in combination with the other therapies in the armamentarium to fight cancer will be an on-going challenge. Antiangiogenic Agents in Cancer Therapy, Second Edition provides a current, up-dated perspective on the state of the art of angiogenesis and therapy with a compendium of scientific findings and approaches to the study of angiogenesis in cancer. Leaders in the field present chapters on such topics as the environmental influences and the genetic and physiologic abnormalities that mediate angiogenesis and its role in the progression of malignant disease, working models of tumor angiogenesis, and the role of angiogenesis inhibition in the therapy of malignant disease in humans. Comprehensive and cutting-edge, Antiangiogenic Agents in Cancer Therapy, Second Edition is an ideal, valuable guide to the most recent advances in the field, and a collection that will be useful for many years to come.

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Anterior knee pain and patellar instability

This multidisciplinary book reviews the diagnosis and management of anterior knee pain and patellar instability in an eminently clinical and practical manner. The book reviews the therapeutic alternatives, both surgical and non-surgical, emphasizing the considerable importance of minimal intervention and non-surgical methods. Similarly, anterior knee pain following ACL reconstruction is covered in detail.

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Another side of drugs

Drug interactions remain an important consequence of pharmacologic intervention. It is clear that the pharmacologic response of a drug can be markedly influenced by concurrent administration of another therapeutic agent or food. These interactions may result in a decreased therapeutic effect or in an increase in the amount and extent of untoward reactions. Despite the well-described and real clinical consequences of certain drug interactions, this aspect of patient care often continues to be overlooked.

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Angiogenesis in Inflammation : Mechanisms and Clinical Correlates

This volume relates the lessons learned from tumour biology applied to inflammation. This issue of Angiogenesis in Inflammation: Mechanisms and Clinical Correlates develops current knowledge on the mechanisms at the molecular and cellular levels as they relate to inflammation, including acute and chronic inflammation, neurogenic initiation, and the role of the multiple cellular components that comprise inflammation: granulocytes, macrophages, fibroblasts, dendritic cells and lymphocytes. This is related to inflammatory disease: not only the familiar angiogenesis dependent diseases of rheumatoid arthritis and psoriasis, but also loci such as the lung, gastric ulcers, the eye with uveitis, wound healing and periodontal disease and their therapy, how this knowledge may be used in the discovery of novel therapeutics. The volume brings together experts in each of these fields to link the molecular and cellular processes in angiogenesis to those of inflammation and disease, culminating in a discourse on areas for future therapies.

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Angiogenesis and Direct Myocardial Revascularization

In Angiogenesis and Direct Myocardial Revascularization, an interdisciplinary panel of pioneers and opinion leaders review the basic, preclinical, clinical, and developmental pathways to new treatment strategies, such as therapeutic angiogenesis and myogenesis.

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An introduction to bioanalysis of biopharmaceuticals

Provides a comprehensive review of the fundamental and practical aspects of bioanalytical support and the integral role it plays in the development of safe and efficacious biopharmaceutical drugs with speed and cost-effectiveness. Focuses on a broad range of conventional and emerging biopharmaceutical modalities including monoclonal antibody-based therapeutics, gene therapy, cell therapy, peptides and oligonucleotides.

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Alzheimer's disease : Peptide vaccine and immunotherapy

Peptide vaccines and immunotherapies against aggregating proteins involved in the pathogenesis and progression of Alzheimer's disease (AD) the ẞ-amyloid peptide (Aẞ) and tau are promising therapeutic avenues against AD. Two decades of effort has led to the controversial United States Food and Drug Administration (FDA) approval of the monoclonal antibody Aducamumab (Aduhelm), which has subsequentially sparked the revival and expedited review of promising monoclonal antibody immunotherapies that target Aẞ.

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Alternative medicines for diabetes management : Advances in pharmacognosy and medicinal chemistry

Apart from diet and exercise, the strategic use of different classes of prescribed or non-prescribed xenobiotic compounds for the restoration of euglycemic levels in the body is well known. The ongoing rivalry between the recommended usage of allopathic medicines versus ayurvedic remedies has encouraged many researchers to focus their studies on thoroughly isolating and characterizing the extracts from different parts of plants and then evaluating their relative activities via in vitro, in vivo and in some cases clinical studies.

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Allergic rhinitis

Allergic rhinitis is a very common disorder that affects people of all ages, peaking in the teenage years. It is frequently ignored, underdiagnosed, misdiagnosed, and mistreated, which not only is detrimental to health but also has societal costs. Although allergic rhinitis is not a serious illness, it is clinically relevant because it underlies many complications, is a major risk factor for poor asthma control, and affects quality of life and productivity at work or school. Management of allergic rhinitis is best when directed by guidelines. A diagnostic trial of a pharmacotherapeutic agent could be started in people with clinically identified allergic rhinitis; however, to confirm the diagnosis, specific IgE reactivity needs to be recorded.

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Aging and the Heart : A Post-Genomic View

In this book, the genetic and molecular basis of cardiovascular aging will be discussed. In addition, a comprehensive assessment of the bioenergetic changes that occur in human and animal models of cardiac aging as well as current diagnostic and future therapeutic modalities will be undertaken.

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Advances in Targeted Cancer Therapy

This volume is the first book to cover the general topic of targeted cancer therapy. It presents a range of targets such as tumor angiogenesis, cell cycle control and cell signalling, COX-2, apoptosis/cell survival, invasion and metastasis and approaches like kinase inhibitors, antisense, and antibody-based therapeutics. The emphasis is on preclinical development, including target validation, development of biomarkers, strategies for combination approaches, and development of resistance. The particular challenges involved in translating these data to clinical application are discussed.

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Advances in psoriasis : A multisystemic guide

Provides an up-to-date and highly informative textbook on psoriasis. The understanding of the mechanisms behind the disease and the available treatment options have continued to develop rapidly in recent times, with this vital resource covering the latest in these management options, including targeted T-cell therapy, the use of immunomodulators, systemic therapies, and ultraviolet and laser therapy. In addition, it provides a detailed overview of the pathophysiology, comorbidities, epidemiology and triggers of the disease.

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Advances in flavonoids for human health and prevention of diseases

In response to the recent upsurge of interest in the therapeutic potential of medicinal plants, with their promising phenolic compounds, this new book offers an important overview of advances in the applications of flavonoids for health. The book explores the nutritional and pharmacological properties of polyphenols and flavonoids, including their ability to prevent the start and development of diseases and how they aid in the management of several chronic pathological illnesses, including cancer, diabetes, cardiovascular disease, neuro-degenerative illness and aging, pregnancy-induced disorders, and others. Also discussed in depth are the properties, classes, and degrees that formulate a phenolic compound and which subsequently supports the development of drugs/products with health benefits.

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Advances in Breast Cancer Management, 2nd ed.

Advances in Breast Cancer Management, Second Edition will highlight many of the important advances that have transformed our understanding of the biology and therapeutics of breast cancer.

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Adrenal Glands : Diagnostic Aspects and Surgical Therapy

Surgery of the Adrenal Glands is a comprehensive medical textbook that includes everything that a surgeon, but for all purposes any physicain or medical student, may want to find on adrenal surgery in a friendly, up to date, evidence based manner. 30 of the most renowned names in the field of adrenal surgery from the US and Europe draw on their experience in exploring diagnosis, indications for surgery, choice of operation and operative techniques, and surgical outcomes for every major adrenal condition. Over 200 exquisite illustrations, ranging from intraoperative photographs, line drawings, diagnostic images, pathology slides, tables and graphs are available to make each case discussed comprehensible and easy to follow. Traditional and novel therapeutic recommendations are introduced and the latest developments in minimal-access operative techniques are discussed and reviewed. Finally, the best approaches in dealing with challenging conditions such as adrenal incidentaloma, subclinical Cushing's syndrom, Congenital Adrenal Hyperplasia, Mineralcorticoid Express Syndrome, Extraadrenal and Malignant Pheochromocytoma are discussed.

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Adhesive restoration of endodontically treated teeth

Dentine bonding systems, composite resins and fibre posts have widely replaced cast posts and amalgam as core materials; all-ceramic and composite crowns have also replaced metal ceramic crowns in many aesthetic cases. The aim of this book is to provide the general practitioner with some principles and techniques for the adhesive restoration of root filled teeth.

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Adaptogens : Herbs for strength, stamina, and stress relief

Includes a Materia Medica with monographs covering 25 adaptogens, including eleuthero, ginseng, rhodiola, schisandra, ashwagandha, licorice, shatavari, reishi, and holy basil, as well as complementary nervines, restorative tonics, and nootropics Explains how adaptogens increase the body's resistance to adverse influences, increase energy and stamina, and counter the effects of age and stress on the body Details the actions, properties, preparation, and dosage for each herb and their uses in Ayurveda and Chinese medicine and as remedies for animals Every day our bodies strive to adapt and stay balanced, energized, and healthy, yet chronic stress and the resulting elevation of stress hormones such as cortisol have been shown to be major factors behind not only fatigue and weight gain but also many chronic and degenerative diseases

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Acute Myelogenous Leukemia

The focus is on selected critical molecular determinants of AML pathogenesis and pathophysiology and the exploitation of these factors by diverse therapeutic agents and modalities. Bringing together new concepts and findings in the basic and clinical science of AML, the book emphasizes the molecular basis for new therapies that stand to have the greatest potential impact on the clinical face of these diseases. The text provides insights into selected novel strategies currently and prospectively being developed, including interruption of specific signal transduction pathways, modulation of gene expression, attempts to reinstate differentiation, and immunomodulation.

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Acute Ischemic Stroke : Imaging and Intervention

Acute Ischemic Stroke: Imaging and Intervention is a comprehensive presentation of the state-of-the-art in the diagnosis and treatment of acute ischemic stroke. This book offers a practical review of recent advances in stroke neuroimaging, and the latest therapeutic options for this disease.

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