الصفحة 20
الصفحة 20
Cardiovascular Medicine
Cardiovascular Medicine, 3rd edition" offers the most up-to-date, user-friendly guidance on the evaluation, diagnosis and medical and surgical treatment of heart and vascular disease and will be relevant to the practice of every cardiologist, cardiac surgeon, vascular surgeon, diabetologist, cardiac radiologist and any physician who manages cardiac patients. Drs Willerson, Cohn, Wellens and Holmes – and over 150 world authorities – offer their decades of scientific and clinical experience. The book and DVD are designed to provide comprehensive coverage of every aspect of cardiovascular medicine from cardiac signs and symptoms .
Cancer du sujet âgé = Cancer in the elderly
Etablir un diagnostic précoce, définir une stratégie adaptée et offrir une meilleure qualité de vie chez le sujet âgé atteint de cancer constituent les défis de l’Oncologie de ce début de siècle. Cet ouvrage a pour objectif de proposer aux médecins et aux étudiants un condensé des différents aspects de l’oncologie sur le sujet âgé. Dans une première partie, les aspects épidémiologiques et biologiques ainsi que l’évaluation gériatrique multiparamétrique sont abordés. Les particularités de l’application de la chimiothérapie, de la radiothérapie et de la chirurgie au sujet âgé sont passées en revue. Dans une troisième partie, la stratégie thérapeutique multidisciplinaire est ensuite détaillée par site.
Cancer drug safety and public health policy : A changing landscape
Description and analysis of recent developments and current trends in health policy with regard to cancer drug safety. Opens with an overview of pharmacovigilance for cancer blockbuster drugs, covering both general considerations and efforts to develop a structured framework for the identification and reporting of adverse drug reactions (ADRs). A number of important examples of serious ADRs to hematology and oncology drugs are then reviewed, with evaluation of the lessons learned and the policy implications of the ensuing legal cases and their settlements. Further, the difficulty of reporting such blockbuster side effects in the medical literature is explored in an empirical study. Significant advances have been achieved in analytic methods for the identification of ADRs, and here there is a particular focus on the value of optimal discriminant analysis. Finally, the impacts on pharmacovigilance and drug safety of the huge fines paid under the U.S. False Claims Act relating to the defrauding of governmental programs also receive careful attention – these fines are playing an important role in changing the landscape for pharmaceutical safety.
Cancer Chemoprevention ; Vol.2 : Strategies for Cancer Chemoprevention
In Cancer Chemoprevention, Volume 2: Strategies for Cancer Chemoprevention, leading chemopreventives investigators comprehensively describe the exciting methodologies that are accelerating progress in the chemoprevention field and review the state of clinical development of preventive agents in the major human cancer target organs. The authors provide sound guidelines for cancer chemopreventive drug development, detailing general strategies and methods for drug discovery, preclinical efficacy, characterization of precancers, safety evaluation of clinical cohorts, and clinical trial design.
Calcolo stocastico per la finanza = Stochastic Calculation for Finance
Offers an introduction to the mathematical, probabilistic and numerical methods that are the basis of the models for the valuation of derivative instruments, such as options and futures, dealt with in modern financial markets. The book is aimed at readers with scientific training, wishing to develop skills in the field of stochastic calculus applied to finance.
Buildings for Education: A Multidisciplinary Overview of The Design of School Buildings
This book presents theoretical and practical research relating to the vast, publicly financed program for the construction of new schools and the reorganization of existing educational buildings in Italy.
Building to suit the climate : A handbook
Serves as a concrete aid to planning and design. With the planning process as its roadmap, it accompanies the planner from the basic evaluation stage through conception and implementation planning all the way to building operation. The building-related characteristics of the various climatic zones form the basis for the made-to-measure development of integrated building solutions. Well-conceived graphics illustrate planning contexts and facilitate efficient planning decisions and realistic predimensioning. Materials, systems, and technologies are described, and their areas of application are pointed out. Reference parameters, costs, and the presentation of interrelationships equip the planner to make a strategic and well-informed selection.
Building Services Design for Energy Efficient Buildings
"The following issues are addressed: background issues on climate change, whole-life performance and design collaboration / generic strategies for energy efficient, low-carbon design / health and wellbeing and post occupancy evaluation / building ventilation / air conditioning and HVAC system selection / thermal energy generation and distribution systems / low-energy approaches for thermal control / electrical systems, data collection, controls and monitoring / building thermal load assessment / building electric power load assessment / space planning and design integration with other disciplines."
Building Physics : Heat, Ventilation, Moisture, Light, Sound, Fire, and Urban Microclimate
Presents the theoretical background of building physics, dealing with the evaluation of physical phenomena related to heat transfer and energy use in buildings, water and water vapour transfer in building structures, daylighting and electric lighting of buildings, sound transmission in building structures and protection against noise, the occurrence and spread of fires in buildings and the thermal response of cities. It contains numerical and computational evaluation methods, numerous computational case studies and examples of experimental analyses. The book demonstrates that the considered physical processes affect the quality of living and working comfort in indoor and outdoor environment.
Bringing the Jobless into Work? : Experiences with Activation Schemes in Europe and the US
Over the last decade, many industrialized countries shifted from passive unemployment and welfare benefit regimes and traditional active labor market and social policies to activation strategies by making benefit receipt conditional upon accepting job offers or participation in active labor market schemes. But countries differ with regard to the design of activation instruments and their implementation, the definition of target groups and the effects of activation in the national labor market setting. This volume provides an up-to-date overview of activation strategies in unemployment benefit systems and social assistance in selected European countries and the US. A particular focus lies on the development of activation schemes, governance and implementation as well as on the outcomes of activation in terms of labor market and social integration. The volume is the first to address these issues both from a socio-economic and a legal perspective.
Brain and Human Body Modeling 2020 : Computational Human Models Presented at EMBC 2019 and the BRAIN Initiative® 2019 Meeting
This book describes modern applications of computational human modeling in an effort to advance neurology, cancer treatment, and radio-frequency studies including regulatory, safety, and wireless communication fields.
Brain and Human Body Modeling : Computational Human Modeling at EMBC 2018
This book describes modern applications of computational human modeling with specific emphasis in the areas of neurology and neuroelectromagnetics, depression and cancer treatments, radio-frequency studies and wireless communications. Special consideration is also given to the use of human modeling to the computational assessment of relevant regulatory and safety requirements. Readers working on applications that may expose human subjects to electromagnetic radiation will benefit from this book’s coverage of the latest developments in computational modelling and human phantom development to assess a given technology’s safety and efficacy in a timely manner.
Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics
In this newly updated second edition of Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics, William B. White, MD, and a panel of highly distinguished clinicians give a critical review of every aspect of the evaluation of high blood pressure. This includes home and ambulatory blood pressure monitoring, the relationship between whole-day blood pressure and the cardiovascular disease process, and the effects of antihypertensive therapies on these blood pressure parameters. World-class contributors describe the significant advances in our understanding of the circadian pathophysiology of cardiovascular disorders and demonstrate that ambulatory blood pressure values are independent predictors of cardiovascular morbidity and mortality.
Biotechnology for Odor and Air Pollution Control
An international board of authors from universities, research institutes, and industries describe various biotechnological methods ranging from laboratory, to pilot evaluation and to full-scale process implementation. Topics include bioprocesses for the treatment of odors and air pollutants in wastewater treatment plants, rendering plants, chemical production facilities, and food and flavor manufacturing facilities. In addition to the basic microbiological and engineering aspects, the design, modeling and control of bioreactors are also presented.
Biosaline Agriculture and Salinity Tolerance in Plants
This volume focuses on reclamation, management, and utilization of salt-affected soils, their sustainable use, and evaluation of plants inhabiting naturally occurring saline habitats. It is of interest to scientists and students as well as to agricultural institutions and farmers and will undoubtedly raise the scientific community's awareness of, and interest in salinity issues.
Biometric systems : Technology, design and performance evaluation
The use of computers to recognize humans from physical and behavioral traits dates back to the digital computer evolution of the 1960s. But even after decades of research and hundreds of major deployments, the field of biometrics remains fresh and exciting as new technologies are developed andoldtechnologiesareimprovedandfieldedinnewapplications.Wor- wide over the past few years,there has been a marked increase in both g- ernment and private sector interest in large-scale biometric deployments for accelerating human–machine processes, efficiently delivering human services, fighting identity fraud and even combating terrorism. The p- pose of this book is to explore the current state of the art in biometrics- tems and it is the system aspect that we have wished to emphasize. By their nature, biometric technologies sit at the exact boundary of the human–machineinterface.Butlikealltechnologies,bythemselvestheycan provide no value until deployed in a system with support hardware, n- work connections, computers, policies and procedures, all tuned together to work withpeople to improve some real business process within a social structure.
Biomedical applications and toxicity of nanomaterials
Covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of information for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs.
Bioactive Marine Natural Products
Bioactive Marine Natural Products is the first book available that covers all aspects of bioactive marine natural products. It fills the void in the literature for bioactive marine natural products. The book covers various aspects of marine natural products and it is hoped that all the major classes of bioactive compounds are included. Different classes of marine organisms and the separation and isolation techniques are discussed. The chemistry and biology of marine toxins, peptides, alkaloids, nucleosides and prostanoids are discussed in detail. Biological, toxicological and clinical evaluations are also dealt with to ensure that the book may be adopted at any stage by any practicing organic chemist or biologist, working in academia or in R&D divisions of pharmaceutical companies. Each chapter in the book includes an abstract to highlight the major points discussed in the text and concluding remarks are given. References to books, monographs, review articles and original papers are provided at the end of each chapter.
Big data analysis of nanoscience bibliometrics, patent, and funding data (2000-2019)
Presents an evaluation of nanotechnologies outputs (academic outputs and patents) and their impact from 2000-2019. The evaluation uses Elsevier’s Scopus (the largest abstract and citation database of peer-reviewed literature), SciVal (a scientific research analysis platform), Funding Institutional (a funding database), and PatentSight (a patent analysis platform). It covers four key topics regarding nanoscience research, including: 1) An overview of nano-related scholarly output, 2) Nanoscience and its contribution to basic science, 3) Nanoscience and its impact on and collaboration with industry partners, and 4) Key factors that promote the development of nanoscience.
Beyond Kyoto : A new global climate certificate system : Continuing Kyoto commitsments or a global ´Cap and Trade´ scheme for a sustainable climate policy?
This book shows how humankind can ‘prevent dangerous interference with the c- mate system’ without dangerous interference with the global economic system. In the two underlying studies on behalf of the Ministry of Environment and Transport of i the German federal state of Baden-Württemberg, the results have been elaborated through scientific evaluation of different climate protection systems and intensive developmental work on an efficient climate protection system. The results will be presented in nine chapters according to the following nine basic R&D steps: 1. Quantifying the ‘ultimate climate objective’ of the world community in order ‘to prevent dangerous interference with the climate system,’ thus achieving climate sustainability; 2. Development of a comprehensive standard system for evaluating the prospect of success for different climate protection systems; 3. Based on this scientific standard system, evaluation of the current Kyoto system and of the most important proposals for ‘incremental regime evolution’ of the Kyoto system. Unfortunately, it must be noted that these systems are incapable of achi- ing climate sustainability; 4. Evaluating three proposals for ‘structural regime change’ of the Kyoto system. Following this objective evaluation process and numeric comparison of the diff- ent proposals, 5. Description of the eight basic elements of GCCS and its in-depth ‘critical asse- ment;’ 6.
