الصفحة 2
الصفحة 2
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Hepatocellular Cancer : Diagnosis and Treatment

Recent advances in the use of ultrasound and computed tomography, in new drugs and drug combinations, as well as with increasingly successful liver transplantation have transformed not only our understanding of hepatocellular cancer (HCC), but also our clinical management of the disease. In Hepatocellular Cancer: Diagnosis and Treatment, highly experienced clinicians-many from Dr. Thomas Starzl's renowned liver transplant team at the University of Pittsburgh-present a fully synthesized practical approach to HCC patient management, including an up-to-date literature review. Their presentation includes all the latest developments in the diagnosis and treatment of primary liver cancer. A summary chapter details for physicians the diagnostic and therapeutic decision-making process for dealing with such problems as incidental tumors in the liver transplant, the role of neo-adjuvant chemotherapy, intra-arterial vs intravenous therapy, the uses of embolization, and the significance of portal vein thrombus. A value-added compact disk containing a companion ebook version of Hepatocellular Cancer: Diagnosis and Treatment is included for downloading and use in the reader's PC or PDA. Authoritative and highly practical, Hepatocellular Cancer: Diagnosis and Treatment captures for physicians the recent exciting changes in our understanding of hepatocellular cancer, focusing on today's optimal diagnostic methods, novel therapeutics, and day-to-day best management practices.

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Heat Shock Proteins in Cancer

Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery.

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Head and Neck Cancer Imaging ; 3rd ed.

This book is a comprehensive guide to imaging as a crucial part of the multidisciplinary approach to head and neck cancer management. Readers will find a detailed overview of the findings obtained using different imaging techniques during the evaluation of head and neck neoplasms, both before and after therapy. All anatomic areas in the head and neck are covered, and the impact of imaging on patient management is discussed in detail. Full account is taken of the rapid technological developments of recent years, with explanation of the potential applications, limitations, and advantages of existing and evolving imaging technologies – vital knowledge for all members of the multidisciplinary team. The authors are recognized experts in the field, and numerous high-quality images are included. This third edition includes information on the latest imaging developments in this area as well as the most recent staging classification of head and neck cancer.

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Genetic Engineering of Mesenchymal Stem Cells

MSC (mesenchymal stem cells) have been reported to initiate revascularization after injury, to facilitate engraftment of blood-forming stem cells, and to reduce the incidence of graft-vs. host disease through their immune-suppressive qualities. Finally, bone marrow-derived MSC have been reported to home to areas of solid tumor revascularization, and thus may be used as delivery vehicles to target ablative agents into dividing tumor cells. Recently the characteristics of human MSC from adipose (fat) tissue have also been identified. The possibility of repairing tissues, speeding stem cell engraftment, and targeting solid tumors for specific killing, using MSC easily harvested from bone marrow, or better yet, from unwanted fat tissue, holds broad appeal, and is an intriguing possibility that could have dramatic effect on health care. This book has information on how to isolate, grow, and characterize MSC from marrow and fat, and gives important insight into how these cells may be used for gene delivery and cellular therapies in the future. Updates on emerging clinical trials are given.

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Fundamentals of Pap Test Cytology

Fundamentals of Pap Test Cytology is intended as a practical primer on the Pap test. Using bold text, tables, and highlighted areas, this book offers readers a user-friendly text on Pap test fundamentals so readers may find specific information effortlessly. This book begins with a basic dictionary of terms, principles, and anatomy before detailing such issues as the Bethesda System, liquid-based and physiological cytology, reactive changes, human papillomavirus, and atypical squamous cells. The authors also discuss low-grade and high-grade squamous intra-epithelial lesions, invasive squamous carcinoma, endocervical and endometrial lesions, metastatic tumors, therapy-related changes, and the newest techniques in screening and managing Pap tests.

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Fundamentals of Cancer Detection, Treatment, and Prevention

The book offers a comprehensive overview of cancer in humans, from its causes, symptoms, and diagnosis to the variety of treatment options available today. Intuitively organized by cancer type, this guide provides concise information on risk factors, diagnosis, and treatment options for all commonly encountered tumors, including surgery, radiation therapy, chemotherapy, and immunotherapy.

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Focal liver lesions : Detection, characterization, ablation

Few fields of medicine have witnessed such impressive progress as the diagnosis and treatment of liver tumors. Advances in imaging technology, the development of novel contrast agents, and the introduction of optimized scanning protocols have greatly facilitated the non-invasive detection and characterization of focal liver lesions. Furthermore, image-guided techniques for percutaneous tumor ablation have become an accepted alternative treatment for patients with inoperable liver cancer. This book provides a comprehensive and up-to-date overview of the role of diagnostic and interventional radiology in respect of liver tumors. The volume moves from background sections on methodology and segmental liver anatomy to the main sections on the diagnosis of benign and malignant liver lesions. An integrated approach, focused on the correlation of ultrasound, CT, and MR imaging findings, is presented. Finally, a full section describes the principles, methods, and results of percutaneous tumor ablation techniques.

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Evidence based practice in Neuro-oncology

This book provides evidence-based management in neuro-oncology covering all aspects such as pathology, radiology, surgery, radiation, and chemotherapy.The field of neuro-oncology is rapidly evolving and new evidence is coming out every day towards the optimal management of brain tumors. This necessitates a requirement of a complete guide that shall provide an evidence-based and personalized approach towards dealing with patients. This book also covers recent advances in personalized treatment formed through the relevant basis of anatomy, imaging, radiology, surgical, radiation and systemic treatment of brain and spinal tumors. In addition it also covers the , practical aspects of the planning of the Gamma knife and other radio surgical aspects.

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Epigenetics in oncology

Covers the most recent advances in RNA/histone/DNA epigenetics in Oncology. RNA/histone/DNA epigenetics have been shown to play pivotal roles in cancer initiation, progression, maintenance and drug response/resistance, tumor microenvironment, cancer stem cell self-renewal, cancer metabolism, and tumor immune evasion. In particular, research in RNA cancer epigenetics has made impressive progress in the last few years. Individual chapters in Part I (focusing on RNA epigenetics) are devoted to RNA modifications in Cancer Metabolism and Microenvironment, Cancer Stem Cell Biology, Immune Surveillance, Solid Tumors and Tumor Immunity, and Hematopoietic Malignancies, as well as to RNA editing in Cancer. Chapters in Part II and III of the book focus on histone epigenetics and DNA epigenetics, respectively.

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Enhancing the Role of Ultrasound with Contrast Agents

This bookprovides an up-to-date overview on the clinical value of contrast agents in ultrasound. The volume moves from a background section on technique and methodology to the main sections on the clinical application of contrast ultrasound in the liver and in vascular diseases. A final section discusses results and prospects of contrast ultrasound modality in the other fields.

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Endoscopic Skull Base Surgery : A Comprehensive Guide with Illustrative Cases

To date, more than three thousand brain and skull base tumors, along with various vascular problems, have been treated by using advanced, fully endoscopic, minimally invasive surgical techniques. In Endoscopic Skull Base Surgery, Dr. Hrayr K. Shahinian compiles these techniques.

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EGFR Signaling Networks in Cancer Therapy

EGFR Signaling Networks in Cancer Therapy, is separated into two sections. The first of which probes the molecular pathways and the intersection of signaling networks which are frequently deregulated in human cancers, the second section illustrates the many ways in which EGF receptor contribute to abnormal survival and migration signaling in cancer cells and to epithelial to mesenchymal transition and metastasis.

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Ecografia in oncologia : Testo-Atlante di ultrasonologia diagnostica e interventistica dei tumori = Ultrasound in oncology : Text-Atlas of diagnostic and interventional ultrasound of tumors

Offers detailed information on the key applications of different ultrasound techniques to the study of tumors. The necessary background on the major problems of clinical oncology is provided: screening, identification, characterization and staging of malignant neoplasms, evaluation of the therapeutic response, follow-up. The examination technique and the interpretative principles of all ultrasound techniques are carefully discussed (grayscale ultrasound, color-Doppler, pulsed Doppler, power-Doppler, echocontrastography), with particular attention to the practical aspects, to the "tricks of the trade. "and the potential methodological and semeiological pitfalls. Particular emphasis is placed on those areas where ultrasound plays a decisive role compared to other diagnostic imaging methods, with a practical and original approach, for "clinical problems". The main eco-interventional, diagnostic and therapeutic procedures are illustrated in detail. The very rich iconography, also including a CD-ROM with original videos, punctually integrates the text. A compact and homogeneous work, necessary for all doctors, both radiologists and non-radiologists, who deal with ultrasound.

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Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Oncology

Dynamic contrast-enhanced MRI is now established as the methodology of choice for the assessment of tumor microcirculation in vivo. This is assisting clinical practitioners in the management of patients with solid tumors and is finding prominence in the assessment of tumor treatments, including anti-angiogenics, chemotherapy, and radiotherapy. In this book, targeted at both clinical practitioners and basic scientists, the principles of the methods, their practical implementation, and their application to specific tumor types are discussed by the leading authorities in the field today. The book will serve as an invaluable single-volume reference covering all the latest developments in contrast-enhanced oncological MRI.

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Drugs Affecting Growth of Tumours

During recent years the field of effective anticancer agents has substantially increased. The use of chemotherapy has been accepted as a standard therapy for an expanding number of tumour types and stages, while many new agents are being investigated when standard therapy is lacking or failing. Apart from new targets for anticancer agents, attention is also focused on improving efficacy and tolerability of existing compounds. This topical volume provides an up-to-date overview of clinically relevant data on anticancer agents, and is not only intended for those working as a medical doctor with cancer patients, but also for medical researchers and students. The different classes of anticancer drugs are described by international authorities on the various topics.

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Diagnostic Criteria in Neurology

The criteria cover a wide spectrum of neurological conditions whose diagnosis does not depend solely on histopathology (e.g., brain tumors), including cerebrovascular diseases, dementias and behavioral disorders, demyelinating disorders, and disorders of consciousness and brain death.

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Development of breast cancer therapy and gender

Breast cancer is a disease in which abnormal cells in the breast tissues multiply and form an invasive (or malignant) tumor. Such tumors can invade and damage the tissue around them and spread to other parts of the body through the lymphatic or vascular systems. We will describe in our study several types of breast cancer, since they are classified into two main categories: “invasive” and “non-invasive,” or in situ. While invasive cancer has spread from the breast ducts or glands to other parts of the breast, non-invasive cancer has not spread from the original tissue. Our study will focus on the best tests that examine the breasts which are used to detect and diagnose breast cancer: Physical exam and health history, Clinical breast exam (CBE), Mammogram, Ultrasound exam, MRI (magnetic resonance imaging), Blood chemistry studies and Biopsy. We will include the value of such tests after breast cancer has been diagnosed, to find out if cancer cells have spread within the breast or to other parts of the body.

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Dépistage et cancers cutanés = Skin cancer screening

This work takes stock of the epidemiological aspects of these tumors in France and their clinical aspects. It offers an identification of risk markers and predisposing lesions specific to each tumor type. A strategy for the early diagnosis of carcinoma on the one hand and of melanoma on the other is proposed, relying, in particular for melanoma, on the new methods of care offered today to the patient.

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Deadly Dermatologic Diseases : Clinicopathologic Atlas and Text

Includes understanding of the biologic behavior of pigmented lesions, cutaneous lymphomas, vascular lesions, and soft tissue tumors.It discusses a wide variety of entities–neoplastic, vascular, infectious, metabolic–each of which may eventuate in death of the patient. In addition, numerous tumors and dermatoses frequently associated with internal malignancies are reviewed. High-quality histologic photomic- graphs and clinical pictures accompany many of the discussions.

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Dail and Hammars Pulmonary Pathology : Vol. I: Nonneoplastic Lung Disease

Dail and Hammar’s Pulmonary Pathology has established itself as the definitive reference in the field. This authoritative reference work has been thoroughly updated to cover newly recognized entities and the latest advances in molecular diagnostic techniques.

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