الصفحة 2
الصفحة 2
The EBMT/EHA CAR-T Cell Handbook
Covers several aspects of CAR-T cell treatments, including the underlying biology, indications, management of side-effects, access and manufacturing issues. This book, written by leading experts in the field to enhance readers’ knowledge and practice skills, provides an unparalleled overview of the CAR-T cell technology and its application in clinical care, to enhance readers’ knowledge and practice skills.
The development in cancer therapy and early detection tools
Despite the development in cancer treatment there is still a high rate of mortality worldwide. Although the traditional ways of cancer treatments are still used as a first line therapy, however, new treatments have been developed which showed a high effect on cancer cells. Therefore, the aim of our study is to search for the most recent cancer therapies, such as anti-angiogenesis treatment and immune therapy and related early detection tools. We will focus on the most “resilient” aggressive types of cancers which people have a lack of information about, in order to let them be aware about their risk factors and how to avoid them, and to provide them with their symptoms as well.
The Cell Cycle in the Central Nervous System
Topics covered range from the cell cycle during the prenatal development of the mammalian central nervous system (CNS) to future directions in postnatal neurogenesis through gene transfer, electrical stimulation, and stem cell introduction. Additional chapters examine the postnatal development of neurons and glia, the regulation of cell cycle in glia, and how that regulation may fail in pretumor conditions or following a nonneoplastic CNS response to injury. Highlights include treatments of the effects of deep brain stimulation on brain development and repair; the connection between the electrophysiological properties of neuroglia, cell cycle, and tumor progression; and the varied immunological responses and their regulation by cell cycle.
Textbook of Personalized Medicine
This book is for personalized medicine as a prescription of specific treatments and therapeutics best suited for an individual and considersgenetic as well as environmental factors that influence responses to therapy. Best approaches are described for integration of all available technologies for optimizing the therapy of individual patients. This edition covers the latest advances in personalized medicine and several chapters are devoted to various specialties, particulary cancer which is the largest area of application. The book discusses the development of personalized medicine and various playersin it such as companies, academic institutions, the government, and the public as the consumer of healthcare. Additionally, the roles of bioinformatics, electronic health records, and digital technologies for personalized medicine are discussed.
Targeted cancer therapy in biomedical engineering
Highlights the role of Biomedical Engineering (BME) used in diagnosis (e.g., body scanners) and treatment (radiation therapy and minimal access surgery in order to prevent various diseases). In recent years, an important progress has been made in the expansion of biomedical microdevices which has a major role in diagnosis and therapy of cancer. When fighting cancer, efficacy and speed are of the utmost importance. A recently developed microfluidic chip has enabled a breakthrough in testing the efficacy of specialized cancer drugs. Effective cancer-targeting therapies will require both passive and active targeting strategies and a thorough understanding of physiologic barriers to targeted drug delivery. Targeted cancer treatments in development and the new combinatorial approaches show promise for improving targeted anticancer drug delivery and improving treatment outcomes.
Survivors of Childhood and Adolescent Cancer : A Multidisciplinary Approach
It was not long ago that clinicians would say,“study ed at the 1975 meeting revealed. Among them was the late complications of cancer treatments we give to one based on data collected by the Late Effects Study children? You must be joking! We can start worrying Group, an international consortium that consisted about that when we start curing them! Meanwhile, initially of ?ve, then ten, pediatric centers. This was cure must be our only aim.
Surgery of the Thyroid and Parathyroid Glands
The aim of this text is to create a unique in-depth comprehensive reference covering all surgically relevant thyroid and parathyroid diseases. It is a definite reference presenting the latest information on the management of common and rare disorders of the thyroid and parathyroid glands. International authorities provide detailed discussions on operative techniques and treatments that are accompanied by rationales for particular approaches advocated by the authors. The topics include the description of all surgically relevant pathologies, the preoperative surgical evaluation, decision making, and operative strategies for the different thyroid and parathyroid diseases. In addition, experts present the molecular basis for thyroid neoplasia and the current understanding of the genetics of inherited thyroid and parathyroid diseases. Evolving modern operative techniques like the minimally invasive videoscopic approach to the thyroid and parathyroids are also covered.
Surgery for Sleep-Disordered Breathing
In recent years, the spectrum of therapy for sleep-related breathing disorders has been immensely enriched by numerous innovative surgical procedures and techniques. Deciding which therapy is most appropriate for which patient is often a difficult matter, especially in light of the non-surgical alternatives. This book analyses the efficiency of the recognised surgical procedures; it is rooted in evidence-based medicine. Indications, techniques, complications, and specific follow-up treatments in the realm of sleep medicine have been compiled in the form of a primer. The authors are directors of one of the largest otolaryngological sleep laboratories in the world and perform approximately 1,500 surgical sleep medicine procedures per year. The complete surgical and sleep medicine know-how of the authors, as well as the experience of numerous international courses on sleep surgery, have been incorporated into this volume. It is therefore the fundamental textbook for sleep medicine surgeons.
Stroke Recovery with Cellular Therapies
As the leading cause of adult disability, stroke poses substantial economic and psychological burdens to populations around the world. Against this dismal backdrop, several novel "neurorestorative" approaches are being investigated as adjunctive treatments to physiotherapy. Stroke Recovery with Cellular Therapies discusses the promising investigations around the world on cell-based therapies to enhance recovery from stroke. Throughout this groundbreaking text, chapters detail the potential benefits of various types of cells and approaches for ischemic and hemorrhagic stroke, and all studies rely upon traditional histological and functional outcomes. Among the topics detailed in this volume are transplanting immortalized neural stem cells, transplantation of bone marrow stromal cells, adipose-derived stem cells, endogenous neural stem cells in tissue remodeling, and an investigation into the ethics of stem cell research.
Stem cell therapy for infertility
Globally, infertility affects 8-12% of couples of reproductive age and has become a common problem. There are several ways to treat infertility, including medication, intrauterine insemination, and in vitro fertilization. In recent years, stem cells are looked at as a promising tool for improving infertility treatments in women and men.. Stem cells are self-renewing, self-replicating undifferentiated cells that are capable of producing specialized cells under appropriate conditions. They exist throughout a human’s embryo, fetal, and adult stages and can proliferate into different cells. While many issues remain to be addressed concerning stem cells, stem cells have undeniably opened up new ways to treat infertility. In this review, we describe past, present, and future strategies for the use of stem cells in reproductive medicine.
Spiro Compounds : Synthesis and Applications
Combines discussions of the latest advances in spiro compound research with the most cutting-edge, real-world applications of that knowledge. This book provides in-depth coverage of the history, significance, properties, synthetic methods, and applications of spiro compounds. As interest in spiro compounds grows due to their unique conformational features and their structural implications on biological systems, Spiro Compounds delivers fulsome treatments of advances in spiro compound synthesis (including stereoselective synthesis) methodologies.
Spectroscopy of emerging materials ; Proceedings of the NATO ARW on frontiers in spectroscopy of emergent materials : Recent advances toward new technologies, Sudak, Crimea, Ukraine, from 14 to 18 September 2003.
A comprehensive discussion of the key role of modern spectroscopic investigations in interdisciplinary materials science and engineering, covering emerging materials that are either absolutely novel or well-known materials with recently discovered, exciting properties. The types of spectroscopy discussed include optical, electronic and magnetic, UV-visible absorption, Rayleigh scattering, photoluminescence, vibrational, magnetic resonance, electron energy loss, EXAFS, XANES, optical tomography, time-resolved spectroscopy, and point contact spectroscopy. The materials studied are highly topical, with a focus on carbon and silicon nanomaterials including nanotubes, fullerenes, nanoclusters, metallic superconducting phases, molecular materials, magnetic and charge-stripe oxides, and biomaterials. Theoretical treatments are presented of molecular vibrational dynamics, vibration-induced decay of electronic excited states, nanoscale spin-orbit coupling in 2D Si-based structures, and the growth of semiconductor clusters.
Spatial Econometrics : Selected Essays
In recent years the so-called new economic geography and the issue of regional economic convergence have increasingly drawn the interest of economists to the empirical analysis of regional and spatial data. Spatial econometric techniques receive little or no attention in the major econometric textbooks. Very occasionally the standard econometric textbooks devote a few paragraphs to the subject, but most of them simply ignore the subject. On the other hand spatial econometric books (such as Anselin, 1988 or Anselin, Florax and Rey, 2004) provide comprehensive and - haustive treatments of the topic, but are not always easily accessible for people whose main degree is not in quantitative economics or statistics. This book aims at bridging the gap between economic theory and spatial stat- tical methods.
Soft Computing for Complex Multiple Criteria Decision Making
There are numerous books on Multiple Criteria Decision Making. Soft Computing for Complex Multiple Criteria Decision Making concentrates on providing technical (meaning formal, mathematical, algorithmical) tools to make the user of Multiple Criteria Decision Making methodologies independent of bulky optimization computations. These bulky computations up to now have been a necessary, but limiting, characteristic of interactive MCDM methodologies and algorithms. This book removes these limitations of MCDM problems by reducing a problem's computational complexity. The book systematically applies the approximate — soft — treatments to major MCDM solving methodologies. As a result, it provides a wider and more functional general framework for presenting, teaching, implementing and applying a wide range of MCDM methodologies. The book seeks to provide a stimulus for a broader development and application of MCDM methods.
Smart micro- and nanomaterials for drug delivery
Smart drug delivery at both the micro- and nanoscale is an evolving field with numerous potential applications. It has the potential to revolutionize drug therapy by making treatments more effective, reducing side effects, and improving patient outcomes. This book presents a comprehensive review of the most recent studies on smart micro- and nanomaterials with a focus on their “smart” activity for formation of targeted and responsive drug-delivery carriers.
Skin injuries & conservative treatments
Skin is a barrier which protects the whole human body, however it is exposed to many damaging factors. The aim of our study is to describe the structure of the skin and we will focus on the most common causes of skin damage factors from natural sources such as sun exposure, which could harm the skin and there is a correlation in between it and increasing skin cancer. We will also discuss about wounds and burns since they both became a life threatening factors during the war in Syria therefore we will introduce the best and the most recent treatments and technologies including a case report about healing by stem cells, in order to reduce. Malformation of skin like a scar, and more important we will highlight the importance of new devices in early detection of skin cancer and conservative surgery of breast cancer patients. We were also concerned about the lack of knowledge. So we will mention cosmetic creams and procedures. For anti aging since wrinkles is a major factor of depression.
Skin Cancer Management : A Practical Approach
The incidence of skin cancer continues to rise, as do the challenges physicians face in treating the growing population of skin cancer patients. Skin Cancer Management: A Practical Approach addresses the spectrum of skin cancers from the precancerous to the inoperable. In this revised and updated edition, a wide selection of medical treatments and surgical procedures are described in detail and supplemented with an abundance of full-color figures. Numerous case studies help to illustrate the various techniques.
Sketching from the imagination : Characters
Sketches and drawings are the foundation of great art, where thoughts and concepts first come to life as an image. In Sketching from the Imagination: Characters, fifty talented artists share their sketches, inspirations, and approaches to creating characters. This book is a visually stunning collection packed with useful tips and creative insights- an invaluable resource that will inspire artists of all abilities.
Sindrome Coronarica Acuta, un nuovo modo di fare diagnosi, un nuovo modo di impostare la terapia = Acute Coronary Syndrome : Anew way of diagnosing and setting therapy
Aims to provide the reader with a concise yet comprehensive and up-to-date overview of the issue of acute coronary syndrome, in light of the enormous body of literature published on the subject over the past decade. Introduction to the concepts of electrocardiography and histophysiopathology, the nosological reclassification of acute coronary disease resulting from the introduction of new myocardial necrosis markers into clinical practice is addressed. It also emphasizes the need for physicians to assess the intrinsic risk of the disease by calculating specific scores proposed by clinical studies. Based on these new concepts, the various therapeutic approaches that should be implemented are analyzed, including both purely pharmacological and more "aggressive" approaches in terms of effectiveness. Ample space is therefore given to the use of new antithrombotic treatments and the choice between pharmacological therapy and invasive approaches using coronary angiography and angioplasty. a crossroads that sometimes puts the doctor in difficulty, but which can imply, if the options are faced rationally, a radical change in the patient's destiny.
Scorpion Venom Toxin
Neurotoxins are the main components of scorpion venom that are known to be responsible for the pathological manifestations of envenoming. These venoms are associated with high morbidity and mortality, especially among children. Besides neurotoxins, a wide range of other bioactive molecules can be found in scorpion venoms. Advances in separation, characterization, and biotechnological approaches have enabled not only the development of more effective treatments against scorpion envenomings, but have also led to the discovery of several scorpion venom peptides with interesting therapeutic properties. Thus, scorpion venom may not only be a medical threat to human health, but could prove to be a valuable source of bioactive molecules that may serve as leads for the development of new therapies against current and emerging diseases. The detrimental and beneficial properties of scorpion venom toxins and the newest advances within the development of novel therapies against scorpion envenoming and the therapeutic perspectives for scorpion toxins in drug discovery will be discussed.
