الصفحة 2
الصفحة 2
Handbook of Pediatric Eye and Systemic Disease
Concise yet comprehensive, the chapters in this handbook are reader friendly, organized with clear sub-headings to quickly guide the reader to areas of interest. Excellent, detailed color photographs and diagrams illustrate and enhance the clinical pearls. Extensive use of tables and information boxes helps to simplify and summarize complex topics.Also included is a comprehensive outline of the ocular manifestation of inherited diseases. This chapter provides a clinical snapshot of dozens of congenital conditions and their ocular manifestations.
Guide to periodontal treatment solutions for general dentistry
A concise textbook on periodontics geared towards dental students, residents, and early career general dentists. Each chapter includes cases and evidence-based practice exercises that illustrate key concepts and enable application of these concepts through independent study or non-lecture based teaching methods. This book is arranged in a logical sequence mirroring the manner in which patients present with periodontal disease, from the initial exam to state-of-the art treatments. The opening chapters cover gingivitis and disease basics, data collection, epidemiology, classification systems, and diagnosis. Subsequent chapters encompass a wide array of nonsurgical and surgical approaches for treating issues such as gum pockets, furcation, gingival recession, mucogingival defects, and tooth mobility, as well as when to refer patients. The latest methods for controlling gingival inflammation are discussed, including scaling and root planing, systemic and local antimicrobial therapy, antiseptics, lasers, and photodynamic therapy
Governance : Systemic foundation and framework
Instead of yet another theory on good governance, this book presents a substantiation of contemporary notions. It builds on the theoretical foundations for taking an overall perspective on social contexts and culminates in a systemic framework that captures social structures based on first principles of viability and sustainability. The framework at hand enables applicants to view social contexts holistically while at the same time envisioning a rich picture of what leverages the implementation of social purposes beyond the boxes of the professional disciplines: social structures can be assessed, strengths and weaknesses identified and measures arrived at. Ultimately, the required structures can be tailor-made to align forces for a joint implementation of purposes. Conventional static hierarchies can be deployed into dynamic social organisms capable of developing and adapting continuously according to the opportunities and challenges faced.
Gene Therapy for Cancer
The possibility of treating cancer, a disease defined by genetic defects, by introducing genes targeting these very alterations has led to an immense interest in gene therapy for cancer. Although incremental successes have been realized, enthusiasm for gene therapy has declined due to an increasing number of obstacles. These obstacles include vector systems that do not reach systemic metastases, therapeutic genes with redundant mec- nisms allowing for cellular resistance, and toxicities in clinical trials leading to premature closure of these studies. Different tactics to overcome or circumvent these obstacles have catalyzed the development of a wide range of gene therapy approaches. Thus far, almost two-thirds of gene therapy trials have focused on cancer. This reflects the concept that gene therapy approaches for the treatment of cancer do not necessarily require long-term expression of the gene as is necessary for the treatment of primary genetic defects like hemophilia or juvenile diabetes.
Fluconazole : Pharmacology, clinical uses and health effects
Fluconazole is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. In this book, the authors present current research in the study of the pharmacology, clinical uses and health effects of fluconazole. Topics discussed include the utilization of fluconazole in adult intensive care units; the use of fluconazole in veterinary species and a description of variances from the human experience as well as findings in veterinary species which may have applicability in human medicine; common clinical uses and in vitro activity features on fluconazole; and the discovery and development of medically-important antifungal agents, particularly the azole derivatives and the development of fluconazole and its clinical applications.
Financial crisis management and democracy : Lessons from Europe and Latin America
This book discusses financial crisis management and policy in Europe and Latin America, with a special focus on equity and democracy. Based on a three-year research project by the Jean Monnet Network, this volume takes an interdisciplinary, comparative approach, analyzing both the role and impact of the EU and regional organizations in Latin America on crisis management as well as the consequences of crisis on the process of European integration and on Latin America’s regionalism.
Evidence based practice in Neuro-oncology
This book provides evidence-based management in neuro-oncology covering all aspects such as pathology, radiology, surgery, radiation, and chemotherapy.The field of neuro-oncology is rapidly evolving and new evidence is coming out every day towards the optimal management of brain tumors. This necessitates a requirement of a complete guide that shall provide an evidence-based and personalized approach towards dealing with patients. This book also covers recent advances in personalized treatment formed through the relevant basis of anatomy, imaging, radiology, surgical, radiation and systemic treatment of brain and spinal tumors. In addition it also covers the , practical aspects of the planning of the Gamma knife and other radio surgical aspects.
Essential microbiology for dentistry
Supports a new generation of dental students in their understanding of microbiom and oral microbiota, basic immunology, oral and systemic infections and cross-infection control. Fully updated throughout with the latest developments in oral microbiology, microbiomics, disease prevention and control, Essential Microbiology for Dentistry will be essential for all undergraduates studying dentistry as well as anyone undertaking postgraduate training.
Endodontic Microbiology ; 2nd ed.
Presents a comprehensive reference to the microbiology, pathogenesis, management, and healing of endodontic pathosis, emphasizing the importance of biological sciences in understanding and managing endodontic disease and its interaction with systemic health. Provides a major revision to the first book to focus on the problems related to microbes in the root canal and periapical tissues. Updates current knowledge in endodontic pathosis, especially regarding next generation sequencing and microbial virulence. Presents useful diagrams, images, radiographs, and annotated histological images to illustrate the concepts. Emphasizes the importance of biological science in understanding and managing endodontic disease. Includes contributions from the leading researchers and educators in the field
Endocarditis : Diagnosis and Management
Endocarditis: Diagnosis and Management provides a comprehensive review of the diagnosis and management of endocarditis. It is structured in a practical format and designed to be easy to follow, clinically relevant and evidence based, with emphasis on the key clinical points. These key points are listed in each chapter for quick review.
Drug delivery via nasal route
Over the past 10 years, the interest in intranasal drug delivery has increased. The objective of this research is to summarize recent developments on intranasal administration for local and systemic delivery, as well as for CNS indications. Nasal delivery offers many advantages over standard systemic delivery systems, nevertheless, there are still formulation limitations and side effects to be optimized. Intranasal drug delivery in the field of drug development is an interesting delivery route for the treatment of neurological disorders. Systemic approaches often fail to efficiently supply the CNS with drugs. This research describes the anatomical, histological and physiological basis and summarizes currently approved drugs for administration via intranasal delivery. Further, the research focuses on advantages and disadvantages of intranasal applied compounds and discusses formulation aspects that need to be considered for drug development.
Drug Delivery Approaches : Perspectives from Pharmacokinetics and Pharmacodynamics
Delivers a thorough discussion of drug delivery options to achieve target profiles and approaches as defined by physical and pharmacokinetic models. The book offers an overview of drug absorption and physiological models, chapters on oral delivery routes with a focus on both PBPK and multiple dosage form options. It also provides an explanation of the pharmacokinetics of the formulation of drugs delivered by systemic transdermal routes.
Differential Diagnosis for the Dermatologist
When faced with a challenging dermatologic problem, physicians are often required to do a time-consuming search through large dermatologic texts to find the information on the necessary differential diagnosis. This comprehensive and concise Handbook of Differential Diagnosis for the Dermatologist will shorten this process to a matter of seconds.
Dietary interventions for human general and oral health and disease reduction
Nutrition is considered an integral part of health and oral health in terms of treatment and prevention. Thus, different strategies should be employed, as described in this Special Issue, including weight management and control, the incorporation of probiotics, prebiotics, and dietary supplementation. This Special Issue reprint also covers the aspects of dental and oral health impacting systemic health and quality of life. Hence, risk factors and health behaviors have been identified and discussed. The significance of this Special Issue reprint has been outlined by examining and exploring the effects of diet and nutrition on health and oral health issues that affect well-being and quality of life.
Designing sustainable cities
Emphasizes new ways of designing for a sustainable city and urban environment. From several angles the future of our urbanism is illuminated. From a philosophical point of view, the city is seen as an organism, following complex ecosystemic principles, shining light on indigenous perspectives to become beneficial for sustainable design and core questions are asked whether current architectural practice is really sustainable. Simultaneously concrete practices are presented for cities in transformation, focusing on green infrastructure, smart city principles and health.
Designing Organizations : 21st Century Approaches
The design of organizations has been an ongoing concern of management theory and practice over the past several decades. Over this time, there has been little change in the fundamental theory, principles and concepts of Organization Design (OD). Recently organizational life has changed dramatically with the advent of: new communication systems, adaptive mechanisms, information technology, knowledge management systems, innovation processes and more. This book systemically examines these developments and their impact on OD with contributions from leading scholars in the area. Also featured in the book are the practical issues with implementing OD in organizations. The individual chapters are organized into five sections: (1) Putting Contingency Theory in its Place, (2) Focus on Individuals Who Make up the Organization, (3) Innovation Processes and Organization Design, (4) Adaptation and Technology, and (5) Design for Performance. Each chapter examines aspects of the book’s threefold theme: (1) core issues in organization design, (2) emerging theoretical perspectives in OD, and (3) new developments and directions in OD. A special feature of each chapter is: 1) implications for theory, and 2) implications for practice.
Dental Sleep Medicine A Clinical Guide
Enables dentists to understand various aspects of dental sleep medicine, and to recognize the signs and symptoms of sleep disorders in their patients. It discusses potential negative impact of a sleep disorder on oral and systemic health, and shows how to collaborate with others in order to implement appropriate patient management. The first part of the book concentrated on the scientific background of sleep medicine in connection to dentistry covering the physiology of sleep, classifications of sleep disorders, their diagnosis as well as medical and dental comorbidities. The second part of the book is dedicated to clinical applications like CPAP therapy, oral appliance therapy, surgical procedures and adjunct therapies. Last, the future of dental sleep medicine is discussed.
Dental implant treatment in medically compromised patients
This book is an ideal reference guide for clinicians seeking to improve their decision making and treatment outcomes when placing dental implants in medically compromised patients, in whom conditions for osseointegration and soft tissue healing may be unfavorable.
Cutaneous Lupus Erythematosus
Lupus erythematosus is a chronic inflammatory autoimmune disease characterized by a wide spectrum of manifestations with a variable evolution. There has been a long-standing need for a book with a unifying concept on the cutaneous manifestations of this disease. The book is based on multidisciplinary knowledge and is written by leading clinicians and scientists. It provides not only a comprehensive description of the vast variety of cutaneous abnormalities but also a synthesis of the relationship between cutaneous and systemic changes, including chapters on classification and clinical aspects, pathogenesis and pathologic features, and treatment and management of lupus erythematosus.
Curcumin : clinical uses, health effects and potential complications
Curcumin is a natural product with polyphenolic structure. It is used in therapeutic remedies alone or in combination with other natural substances. Many researchers are investigating it because of its biological activities such as: anti-inflammatory, anti-cancer, anti-protozoal, anti-viral, anti-bacterial and has been found to be effective for treatment of Alzheimer, depression, headaches, fibromyalgia, leprosy, fever, menstrual problems, water retention, worms and kidney problems etc. It is an active ingredient in dietary spice, turmeric. It has reactive functional groups: a diketone moiety and two phenolic groups. Despite its unique biological activities, it suffers from some shortcomings which include: gastrointestinal problems, poor bioavailability due to its poor absorption, short half-life, poor solubility in aqueous solutions, rapid systemic elimination and antithrombotic activity which can interfere with blood clotting. The first chapter of this book reviews the different delivery systems used for incorporation of curcumin and its derivatives, release kinetics and up to date in vivo results. Chapter two discusses curcumin nano and microencapsulation and its implications on clinical uses.
