الصفحة 2
الصفحة 2
Multivariate Statistical Machine Learning Methods for Genomic Prediction
This book brings together the latest genome base prediction models currently being used by statisticians, breeders and data scientists. It provides an accessible way to understand the theory behind each statistical learning tool, the required pre-processing, the basics of model building, how to train statistical learning methods, the basic R scripts needed to implement each statistical learning tool, and the output of each tool. To do so, for each tool the book provides background theory, some elements of the R statistical software for its implementation, the conceptual underpinnings, and at least two illustrative examples with data from real-world genomic selection experiments.
Multiobjective Problem Solving from Nature : From Concepts to Applications
he book focuses on how MOEAs and related techniques can be used to solve problems, particularly in the disciplines of science and engineering. Contributions by leading researchers show how the concepts of multiobjective optimization can be used to reformulate and resolve problems in broad areas such as constrained optimization, coevolution, classification, inverse modelling and design. The book is distinguished from other texts on MOEAs in that it is not primarily about the algorithms, nor specific applications, but about the concepts and processes involved in solving problems using a multiobjective approach. Each chapter contributes to the central, deep concepts and themes of the book: evaluating the utility of the multiobjective approach; discussing alternative problem formulations; showing how problem formulation affects the search process; and examining solution selection and decision making.
Multi-Objective Machine Learning
This monograph presents a selected collection of research work on multi-objective approach to machine learning, including multi-objective feature selection, multi-objective model selection in training multi-layer perceptrons, radial-basis-function networks, support vector machines, decision trees, and intelligent systems.
Multimedia Services in Intelligent Environments : Advanced Tools and Methodologies
This book presents a sample of recent research results in multimedia services. Besides the introductory chapter, this book includes fourteen additional chapters. Nine of these chapters cover various aspects of data processing in multimedia services in intelligent environments, such as storage, recognition and classification, transmission, information retrieval, and information securing. Four additional chapters present multimedia services in noise and hearing monitoring and measuring, augmented reality, automated lecture rooms and rights management and licensing. Finally, the last chapter is devoted to an intelligent recommender service in scientific digital libraries.
Multimedia Semantics : The Role of Metadata
This book gives an overview on fundamental issues within the field of multimedia metadata focusing on contextualized, ubiquitous, accessible and interoperable services on a higher semantic level. The book in hand provides a selection of basic articles being a base for multimedia metadata research. Furthermore it presents a view on the current state of the art in multimedia metadata research.
Molecular Targeting in Oncology
In Molecular Targeting in Oncology, authors present an overview of the development of targeted therapies for the treatment of cancer with an emphasis on clinical application. The volume covers the complexity of the rapidly developing area of targeted therapies for the treatment of patients with cancer and is structured in a way so readers may begin with chapters that most interest them and work through the rest of the chapters in the order of their choice. The volume is divided into five sections that cover the most important elements of drug development. The first section focuses on approaches using targeted therapies to inhibit cell growth. The second section describes how clinicians are evaluating targeted therapies in specific organ systems. The third section illustrates how various classes of pharmacologic and immunologic agents are developed for individual molecular targets. The fourth section details new drugs that have novel mechanisms of action. The final section looks to the future of targeted therapeutics and includes chapters on appropriate patient selection, use of combination therapy, dealing with tumor cell resistance, and more. Comprehensive and cutting-edge, Molecular Targeting in Oncology is an essential reference for those working in the field.
Molecular Marker Systems in Plant Breeding and Crop Improvement
Successful release of new and better crop varieties increasingly requires genomics and molecular biology. This volume presents basic information on plant molecular marker techniques from marker location up to gene cloning. The text includes a description of technical approaches in genome analysis such as comparison of marker systems, positional cloning, and array techniques in 19 crop plants. A special section focuses on converting this knowledge into general and specific breeding strategies, particularly in relation to biotic stress. Theory and practice of marker assisted selection for QTL, gene pyramiding and the future of MAS are summarized and discussed for maize, wheat, and soybean. Furthermore, approaches in silviculture on the examples of Fagus, Populus, Eucalyptus, Picea and Abies are presented. The volume ends with a comprehensive review of the patents relevant for using molecular markers and marker assisted selection.
Molecular Biology of Human Cancers: An Advanced Student's Textbook
Presents many of the molecules and mechanisms generally important in human cancers. Following an overview on the cancer problem, individual chapters deal with cancer genetics and epigenetics, DNA damage and repair, oncogenes, tumor suppressors, regulatory pathways in cancer, apoptosis, cellular senescence, tumor invasion, and metastasis. A consensus is emerging that while these common mechanisms and molecules are all relevant to human cancers, in each cancer type (or even subtype) a selection of them are extremely important. For selected cancers, the route from genetic and epigenetic changes to their biological and clinical behavior can already be traced. Part II of the book presents a broad, but exemplary selection of cancers that serve as paradigms to illustrate this point. In fact, cancer research has now reached a critical stage, in which the accumulated knowledge on molecular mechanisms is gradually translated into improved prevention, diagnosis, and treatment. The state, pitfalls, and potential of these efforts are summarized in Part III. More than ever, cancer research is now an interdisciplinary effort which requires a basic knowledge of commonly used terms, facts, issues, and concepts. The aim of this book is to provide advanced students and practitioners of different disciplines with this basis, bridging the gap between standard textbooks of molecular biology, pathology, and oncology on the one hand and the specialized cancer literature on the other.
Modern Operator Theory and Applications : The Igor Borisovich Simonenko Anniversary Vol.
This volume is dedicated to the eminent Russian mathematician Igor Borisovich Simonenko on the occasion of his 70th birthday. It consists of a selection of 15 original contributions written by leading experts in operator theory. The topics reflect the wide range and the rich variety of areas of interests, achievements and influence of I.B. Simonenko. The book also includes his biography, the complete list of publications and a list of his Ph.D. students.
Modeling, Simulation and Optimization of Complex Processes ; Proceedings of the Third International Conference on High Performance Scientific Computing, March 6–10, 2006, Hanoi, Vietnam
This proceedings volume contains a selection of papers presented at the Third International Conference on High Performance Scientific Computing held at the Hanoi Institute of Mathematics, Vietnamese Academy of Science and Technology (VAST), March 6-10, 2006. The conference has been organized by the Hanoi Institute of Mathematics, Interdisciplinary Center for Scientific Computing (IWR), Heidelberg, and its International PhD Program ``Complex Processes: Modeling, Simulation and Optimization'', and Ho Chi Minh City University of Technology. The contributions cover the broad interdisciplinary spectrum of scientific computing and present recent advances in theory, development of methods, and applications in practice. Subjects covered are mathematical modelling, numerical simulation, methods for optimization and control, parallel computing, software development, applications of scientific computing in physics, chemistry, biology and mechanics, environmental and hydrology problems, transport, logistics and site location, communication networks, production scheduling, industrial and commercial problems.
Modeling, Simulation and Optimization of Complex Processes ; Proceedings of the International Conference on High Performance Scientific Computing, March 10-14, 2003, Hanoi, Vietnam
This proceedings volume contains a selection of papers presented at the symposium "International Conference on High Performance Scientific Computing'' held at the Hanoi Institute of Mathematics of the Vietnam National Center for Natural Science and Technology (NCST). The contributions cover the broad interdisciplinary spectrum of scientific computing and present recent advances in theory, development of methods, and applications in practice. Subjects covered are mathematical modelling, numerical simulation, methods for optimization and optimal control, parallel computing, symbolic computing, software development, applications of scientific computing in physics, chemistry, biology and mechanics, environmental and hydrology problems, transport, logistics and site location, communication networks, production scheduling, industrial and commercial problems.
Modeling and simulation tools for emerging telecommunication networks : Needs, trends, challenges and solutions
This book contains a selection of papers presented at a symposium organized under the aegis of COST Telecommunications Action 285. The main objective of the Action is to enhance existing tools and develop new modeling and simulation tools for research in emerging multi-service telecommunication networks in the areas of model performance improvements, multilayer traffic modeling, and the important issue of evaluation and validation of the new modeling tools.
Mobile Service Computing
This book introduces readers to the background and principles of mobile service computing. It discusses various aspects of service computing in mobile environments, including key methods and techniques for service selection, recommendation, composition, offloading, execution, deployment, and provision.
Mining Complex Data ; ECML/PKDD 2007 Third International Workshop, MCD 2007, Warsaw, Poland, September 17-21, 2007, Revised Selected Papers
This book constitutes the refereed proceedings of the Third International Workshop on Mining Complex Data, MCD 2007, held in Warsaw, Poland, in September 2007, co-located with ECML and PKDD 2007.The 20 revised full papers presented were carefully reviewed and selected; they present original results on knowledge discovery from complex data. In contrast to the typical tabular data, complex data can consist of heterogenous data types, can come from different sources, or live in high dimensional spaces. All these specificities call for new data mining strategies.
Minimally invasive glaucoma surgery
This book covers all aspects of minimally invasive glaucoma surgery (MIGS) and provides detailed information on each MIGS device, including its mechanism of action; patient selection; implantation techniques; post-operative management; and a review of the existing literature. Step-by-step descriptions are provided for the surgical technique used in implanting each MIGS device, accompanied by clear photographs of each surgical stage. Other areas covered include intra-operative gonioscopy (with tips on optimising the view of the anterior chamber angle) and the management of the intra-operative and post-operative complications. Essential information on the anatomy and physiology of the different aqueous outflow pathways is also included.
Minimally Invasive Bariatric Surgery
This book covers the full spectrum of laparoscopic weight loss surgery and the pathophysiology of obesity. The chapter authors, all currently operating experts in the field, cover the essentials of establishing a bariatric surgery program, including equipment needs, guidelines for training, and patient selection. The operative chapters discuss in full detail the surgical techniques and outcomes, including laparoscopic VGB, laparoscopic adjustable gastric banding, laparoscopic Roux-en-Y, and laparoscopic malabsorption procedures. The text also tackles post-operative issues, such as complications, reoperation, plastic surgery after weight loss, nutritional issues, and pregnancy following obesity surgery.
Midazolam in pediatric dentistry
Discusses predictable ways to achieve minimal/moderate sedation with midazolam. This book covers various aspects of midazolam sedation including pre-operative assessment, case selection, different routes of administration, intraoperative protocol, emergency management and meticulous documentation. It explains the importance of its conjunction with sound fundamentals of non-pharmacological behavior guidance and good local anesthetic techniques.
Micromanufacturing and Nanotechnology
Micromanufacturing and Nanotechnology is an emerging technological infrastructure and process that involves manufacturing of products and systems at the micro and nano scale levels. Development of micro and nano scale products and systems are underway due to the reason that they are faster, accurate and less expensive. Moreover, the basic functional units of such systems possesses remarkable mechanical, electronic and chemical properties compared to the macro-scale counterparts. Since this infrastructure has already become the prefered choice for the design and development of next generation products and systems it is now necessary to disseminate the conceptual and practical phenomenological know-how in a broader context. This book incorporates a selection of research and development papers. Its scope is the history and background, underlynig design methodology, application domains and recent developments.
Micro-, Meso- and Macro-Dynamics of the Brain
This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The topics cover the most fascinating facets of neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory and mental illness, brain controlled robots, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Overall, this volume offers an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Metalearning : Applications to Automated Machine Learning and Data Mining
This book as one of the fastest-growing areas of research in machine learning, metalearning studies principled methods to obtain efficient models and solutions by adapting machine learning and data mining processes. This adaptation usually exploits information from past experience on other tasks and the adaptive processes can involve machine learning approaches. As a related area to metalearning and a hot topic currently, automated machine learning (AutoML) is concerned with automating the machine learning processes. Metalearning and AutoML can help AI learn to control the application of different learning methods and acquire new solutions faster without unnecessary interventions from the user.
