الصفحة 2
الصفحة 2
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New Algorithms for Macromolecular Simulation

Molecular simulation is a widely used tool in biology, chemistry, physics and engineering. This book contains a collection of articles by leading researchers who are developing new methods for molecular modelling and simulation. Topics addressed here include: multiscale formulations for biomolecular modelling, such as quantum-classical methods and advanced solvation techniques; protein folding methods and schemes for sampling complex landscapes; membrane simulations; free energy calculation; and techniques for improving ergodicity. The book is meant to be useful for practitioners in the simulation community and for those new to molecular simulation who require a broad introduction to the state of the art.

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Neurology Study Guide : Oral Board Examination Review

The book is divided into two parts. Part 1 is devoted to practical tips on the exam’s structure, its etiquette and preparation. Particular emphasis is placed on reasons for failing the exam. Part 2 provides sample adult and pediatric vignettes, mirroring that part of the oral Board. Each vignette is presented in a format similar to the exam’s format. Each case provides a differential diagnosis, most likely diagnosis and treatment recommendations. Where relevant, potential pitfalls, do’s and don’ts, musts and shoulds and frequently asked questions, complement the case discussion.

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Neuroeconomia, neuromarketing e processi decisionali = Neuroeconomics, neuromarketing and decision-making processes

The book covers a sector, that of the application of modern neuroscience techniques to the fields of economics and marketing, recently born and of great interest to the public, to advertisers as well as to neuroscience scholars. The book presents, in plain language and not for experts in the field, the structure and functioning of the brain (as it is known today) during human decision-making processes. Of interest is the analysis of how the different neuronal systems within the brain can cooperate with each other in generating decisions. All this simple physiological treatment is inserted in the context of the analysis of brain activity while watching commercial clips. In the original study presented in this book, the variables involved were those related to the recall of television advertising in a sample of normal young subjects. This study is simply the first that is carried out of this type in Italy and will be intended to be a reference point for subsequent studies in the sector.

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NEURO-COVID-19 : Neuroinvasive potential and neurological complications of SARS-CoV-2

From the earliest days of the COVID-19 pandemic, there have been reports of significant neurological and psychological symptoms following SARS-CoV-2 infection. This research paper is designed to examine the potential psychoneuroendocrine pathogenic mechanisms by which SARS-CoV-2 elicits psychiatric sequelae, as well as to posit potential pharmacologic strategies to address and reverse these pathologies. Following a brief overview of the presence and prevalence of neuropsychiatric manifestation in COVID-19 patients, we address mechanisms by which SARS-CoV-2 could enter or otherwise elicit changes in the CNS.

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Neurobiology of Human Values

Man has been pondering for centuries over the basis of his own ethical and aesthetic values. Until recent times, such issues were primarily fed by the thinking of philosophers, moralists and theologists, or by the findings of historians or sociologists relating to universality or variations in these values within various populations. Science has avoided this field of investigation within the confines of philosophy. Beyond the temptation to stay away from the field of knowledge science may also have felt itself unconcerned by the study of human values for a simple heuristic reason, namely the lack of tools allowing objective study. For the same reason, researchers tended to avoid the study of feelings or consciousness until, over the past two decades, this became a focus of interest for many neuroscientists

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Neoproterozoic Geobiology and Paleobiology

The Neoproterozoic Era (1000-542 million years ago) is a geological period of dramatic climatic change and important evolutionary innovations. Repeated glaciations of unusual magnitude occurred throughout this tumultuous interval, and various eukaryotic clades independently achieved multicellularity, becoming more complex, abundant, and diverse at its termination. Animals made their first debut in the Neoproterozoic too. The intricate interaction among these geological and biological events is a centrepiece of Earth system history, and has been the focus of geobiological investigations in recent decades. The purpose of this volume is to present a sample of views and visions among some of the growing numbers of Neoproterozoic workers. The contributions represent a cross section of recent insights into the field of Neoproterozoic geobiology.

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Negotiations with Asymmetrical Distribution of Power : Conclusions from Dispute Resolution in Network Industries

In many ways, complex negotiations shape the business arena of regulated network markets. In general, negotiating partners are not equal with regard to their various sources and instruments of power. This book unfolds a differentiated and, at the same time, applicable framework for analyzing and managing negotiations. It creatively combines power and negotiations theories. In addition, it illustrates the findings in a very inspiring way by investigating negotiation episodes in network industries such as telecommunications and railways. Thus, this book is highly relevant for all those wanting to better understand the complex political processes and outcomes in regulated industries, but also for those bearing practical responsibility in regulatory and government affairs and wanting to improve their management performance.

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Nature-Based Flood Risk Management on Private Land : Disciplinary Perspectives on a Multidisciplinary Challenge

This book addresses the various disciplinary aspects of nature-based solutions in flood risk management on private land. In recent decades, water management has been moving towards nature-based solutions. These are assumed to be much more multi-purpose than traditional “grey infrastructures” and seem to be regarded as a panacea for many environmental issues. At the same time, such measures require more – and mostly privately owned – land and more diverse stakeholder involvement than traditional (grey) engineering approaches. They also present challenges related to different disciplines. Nature-based solutions for flood risk management not only require technical expertise, but also call for interdisciplinary insights from land-use planning, economics, property rights, sociology, landscape planning, ecology, hydrology, agriculture and other disciplines to address the challenges of implementing them. Ultimately, nature-based flood risk management is a multi-disciplinary endeavor.

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Natural product experiments in drug discovery

Explores a wide range of evidence-based complementary medicine and various bio-analytical techniques used to define botanical products. Collecting recent work and current developments in the field of contemporary phytomedicine as well as their future possibilities in human health care, the book includes unique contributions in the form of chapters on phytomedicine and screening biological activities explained with diverse hyphenated techniques, as well as issues related to herbal medications, such as efficacy, adulteration, safety, toxicity, regulations, and drug delivery. Written for the Springer Protocols Handbooks series, chapters feature advice from experts on how to best conduct future experiments. Extensive and practical, Natural Product Experiments in Drug Discovery serves as an ideal reference for students, professors, and researchers in universities, R&D institutes, pharmaceutical and herbal enterprises, and health organizations.

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Natural Language Processing – IJCNLP 2004 ; 1st International Joint Conference, Hainan Island, China, March 22-24, 2004, Revised Selected Papers

This book constitutes the thoroughly refereed post-proceedings of the First International Joint Conference on Natural Language Processing, IJCNLP 2004, held in Hainan Island, China in March 2004. The 84 revised full papers presented in this volume were carefully selected during two rounds of reviewing and improvement from 211 papers submitted. The papers are organized in topical sections on dialogue and discourse; FSA and parsing algorithms; information extractions and question answering; information retrieval; lexical semantics, ontologies, and linguistic resources; machine translation and multilinguality; NLP software and applications, semantic disambiguities; statistical models and machine learning; taggers, chunkers, and shallow parsers; text and sentence generation; text mining; theories and formalisms for morphology, syntax, and semantics; word segmentation; NLP in mobile information retrieval and user interfaces; and text mining in bioinformatics.

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Natural Fullerenes and Related Structures of Elemental Carbon

This book provides an up-to-date summary of the state of knowledge on natural fullerenes occurrences and the laboratory techniques used to determine their presence at low concentration in rock samples. It demonstrates that natural fullerenes exist and should be searched for in places not yet considered such as carbon-containing deep-seated crustal rocks.Natural Fullerenes and Related Structures of Elemental Carbon is written for professional astronomers, meteoriticists, earth and planetary scientists, biologists and chemists interested in carbon and hydrocarbon vapor condensation. It is an invaluable resource for practicing research scientists and science teachers in Earth and Planetary Science, Astronomy and Carbon Science.

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National Constitutions in European and Global Governance : Democracy, Rights, the Rule of Law: National Reports

It offers important insights into three areas. First, it explores how constitutions reflect the transfer of powers from domestic to European and global institutions. Secondly, it revisits substantive constitutional values, such as the protection of constitutional rights, the rule of law, democratic participation and constitutional review, along with constitutional court judgments that tackle the protection of these rights and values in the transnational context, e.g. with regard to the Data Retention Directive, the European Arrest Warrant, the ESM Treaty, and EU and IMF austerity measures. The responsiveness of the ECJ regarding the above rights and values, along with the standard of protection, is also assessed. Thirdly, challenges in the context of global governance in relation to judicial review, democratic control and accountability are examined. On a broader level, the contributors were also invited to reflect on what has increasingly been described as the erosion or ‘twilight’ of constitutionalism, or a shift to a thin version of the rule of law, democracy and judicial review in the context of Europeanisation and globalisation processes.

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Nanotechnology-Enabled Sensors

Nanotechnology provides us with tools to create functional materials, devices, and systems by controlling materials at the atomic and molecular scales, and at the same time make use of novel properties and phenomena. Considering that most chemical and biological sensors, as well as many physical sensors, depend on interactions occurring within the nano scale range, the impact that nanotechnology will have on the sensor world is significant. Nanotechnology enabled sensors find applications in several novel fields such as sensing single molecules, bio-hazards, toxic chemicals, gas sensors, process control and diagnostics.

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Nanoscale Transistors : Device Physics, Modeling and Simulation

The book is a useful reference for senior-level or graduate-level courses on nanoelectronics, modeling and simulation. Chapter 1 reviews some basic concepts, and Chapter 2 summarizes the essentials of traditional semiconductor devices, digital circuits, and systems. This material provides a baseline against which new devices can be assessed. Chapters 3 and 4 present a non-traditional view of the MOSFET using concepts that are valid at nanoscale. Chapter 5 applies the same concepts to nanotube FET as an example of how to extend the concepts to revolutionary nanotransistors. Chapter 6 explores the limits of devices by discussing conduction in single molecules.

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Museum of the future

متحف المستقبل هو معلم ثقافي وتقني يهدف إلى استكشاف مستقبل الابتكار والتكنولوجيا والتصميم ويعتبر منصة لعرض الأفكار والمشاريع التي تساهم في تشكيل المستقبل. يعرض المتحف أحدث الابتكارات في مجالات الذكاء الاصطناعي، الروبوتات والتقنيات المستدامة. يعكس المتحف رؤية مستقبلية تسعى إلى أن تكون رائدة في مجالات التكنولوجيا والابتكار.

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Muscle hypertrophy and role of anabolic hormones in bodybuilding

The goal of our research first of all to give an overall view on the physiology of muscles and we will focus on natural elements such as diet and exercises to improve your aim without using chemical drugs, we will also include other factors affecting hypertrophy muscle such as genetic ones since the variation in between two sportive persons might be more than 50 percent determined by heredity which is a very important element and may lead a sportive man to elevate the doses to reach the same development of ideal muscles.

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Multivariable Computer-controlled Systems : A Transfer Function Approach

Having established the ability of the parametric transfer function to solve this problem for single-input, single-output systems in previous work, the authors extend these methods, which incorporate time-dependence, to the idea of the parametric transfer matrix in a complete exposition of analysis and design methods for multiple-input, multiple-output (MIMO) sampled-data systems.

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Multiscale Problems in the Life Sciences : From Microscopic to Macroscopic

The aim of this volume that presents Lectures given at a joint CIME and Banach Center Summer School, is to offer a broad presentation of a class of updated methods providing a mathematical framework for the development of a hierarchy of models of complex systems in the natural sciences, with a special attention to Biology and Medicine. Mastering complexity implies sharing different tools requiring much higher level of communication between different mathematical and scientific schools, for solving classes of problems of the same nature. Today more than ever, one of the most important challenges derives from the need to bridge parts of a system evolving at different time and space scales, especially with respect to computational affordability. As a result the content has a rather general character; the main role is played by stochastic processes, positive semigroups, asymptotic analysis, kinetic theory, continuum theory and game theory.

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Multirate Statistical Signal Processing

This book introduces a statistical theory for extracting information from signals that have di?erent sampling rates. This new theory generalizes the conventional (deterministic) theory of multirate systems beyond many of its constraints.Furthermore,itallowsfortheformulationofseveralnewproblems such as spectrum estimation, time-delay estimation and sensor fusion in the realm of multirate signal processing. I have arrived at the theory presented here by integrating concepts from diverse areas such as information theory, inverse problems and theory of - equalities. The process of merging a variety of concepts of di?erent origin results in both merits and shortcomings. The former include the fresh and - di?erentiated view of an amateur, providing scope of application. The latter include a lack of in-depth experience in each of the original ?elds. Granted, this may lead to gaps in continuity, however it goes without saying that a complete theory can seldom be achieved by one person and in a short time.

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Multiple Testing Procedures and Applications to Genomics

This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. The methods are applied to a range of testing problems in biomedical and genomic research, including the identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments.

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