الصفحة 2
الصفحة 2
Mouse Models of Human Blood Cancers : Basic Research and Pre-clinical Applications
Although it remains an open question among some people whether mice and humans are similar in disease development, the laboratory mouse has emerged as the preeminent animal model for human diseases. This is underscored by the recently completed mouse and human genome projects, which have revealed that mice and humans share the vast majority of their genes, and thus get many of the same diseases, and for the same reasons. Emphasizing why mouse models are valuable in vivo systems for understanding disease mechanisms and developing therapeutic strategies for human blood cancers, "Mouse Models of Human Blood Cancers: Basic Research and Pre-clinical Applications," edited by Shaoguang Li, aims on presenting thorough analyses of the pathological features and the molecular bases of several major types of blood cancer and to describe translational research using mouse cancer models.
Moral reasoning at work : Rethinking ethics in organizations ; 2nd ed.
Moral Reasoning at Work offers a fresh perspective on how to live with them using ethics and moral psychology research. It argues that decision-makers must go beyond compliance and traditional approaches to ethics to prepare for moral dilemmas. The book has been updated with a range of examples from the author’s more recent research, to reflect current issues affecting organizations in the digital age. With two new chapters on artificial intelligence and social media, this new edition provides an up-to-date overview of ethical challenges in organizations.
Moral reasoning at work : Rethinking ethics in organizations ; 1st ed.
Moral dilemmas are a pervasive feature of working life. Moral Reasoning at Work offers a fresh perspective on how to live with them using ethics and moral psychology research. It argues that decision-makers must go beyond compliance and traditional approaches to ethics to prepare for moral dilemmas.
Moral Psychology Today : Essays on Values, Rational Choice, and the Will
This book brings together in one volume some of the very latest developments in moral psychology that were presented at a major American conference in 2004. Moral psychology is a broad area at the intersection of moral philosophy and philosophy of mind and action. Essays in this collection deal with most of the central issues in moral psychology that are of interest to a large number of philosophers today, including important questions in normative ethical theory, meta-ethics, and applied ethics.
Molecular Wires : From Design to Properties
In the emerging field of nanoscience the desire to construct objects which in the molecular scale can resemble and act as macroscopic devices is a constant trend. Amongst the simplest but also most attractive functional component molecular wires are surely the most investigated. The reason for such interest is quite obvious since wires, in today world, are used all around us and are the most indispensable unit to assemble any type of electronic devices.In this issue the synthesis and characterization of molecular wires based on organic or metal complexes components, their properties and some theoretical background will be illustrated.
Molecular autoimmunity
The autoimmune disease paroxysmal cold hemoglobinuria, a rare hemolytic disorder. After a century of research, the list of autoimmune diseases has become impressive. With a prevalence of approximately 5% of the world-wide population, these chronic, debilitating conditions affect almost every major organ of the body and, for reasons that remain unclear, are much more prevalent in woman than in men. Despite our rapidly expanding knowledge of the cellular and molecular pathways that govern a normal immune response, deciphering the precise etiology of autoimmune diseases remains an important challenge. Over the last few years, our understanding of the pathogenesis of autoimmune diseases has improved rapidly, leading to the emergence of elegant immunointervention strategies. Molecular Autoimmunity illustrates how cutting-edge research is continuing to advance our understanding of autoimmune disease mechanisms and identifies novel therapeutic targets that provide a hope for effective future treatments. This volume contains a selected number of exciting advances in unraveling autoimmune reactions, and the resulting new armory of experimental immunotherapies that may lead to new ways of controlling autoimmune reactions.
Modelling and Reasoning with Vague Concepts
This volume outlines a formal representation framework for modelling and reasoning with vague concepts in Artificial Intelligence. The new calculus has many applications, especially in automated reasoning, learning, data analysis and information fusion. This book gives a rigorous introduction to label semantics theory, illustrated with many examples, and suggests clear operational interpretations of the proposed measures. It also provides a detailed description of how the theory can be applied in data analysis and information fusion based on a range of benchmark problems.
Modeling and using context ; 6th International and interdisciplinary Conference, CONTEXT 2007, Roskilde, Denmark, August 20-24, 2007, Proceedings
This volume contains the papers presented at CONTEXT 2007, the Sixth International and Interdisciplinary Conference on Modeling and Using Context. We believe that the papers of this volume represent a snapshot of current work and contribute to both theoretical and applied aspects of research.
Modeling and Retrieval of Context ; 2nd International Workshop, MRC 2005, Edinburgh, UK, July 31-August 1, 2005, Revised Selected Papers
Computing in context has become a necessity in modern and intelligent IT - plications. With the use of mobile devices and current research on ubiquitous computing, context-awareness has become a major issue. However, context and context-awareness are crucial not only for mobile and ubiquitous computing. They are also vital for spanning various application areas, such as collaborative softwareand Web engineering,personaldigital assistantsand peer-to-peer inf- mation sharing, health care work?ow and patient control, and adaptive games and e-learning solutions. In these areas, context serves as a major source for reasoning, decision making, and adaptation, as it covers not only application knowledge but also environmental knowledge.Likewise, modeling and retrieving context is an important part of modern knowledge management processes.
Model-Based Reasoning in Science, Technology, and Medicine
The volume is based on the papers that were presented at the international conference Model-Based Reasoning in Science and Medicine (MBR’06 China), held at Sun Yat-sen University, Guangzhou, P.R. China in July 2006. The presentations given at the conference explored how scientific thinking uses models and explanatory reasoning to produce creative changes in theories and concepts. Some addressed the problem of model-based reasoning in technology, and stressed the issue of technological innovation and medical reasoning. The various contributions of the book are written by interdisciplinary researchers who are active in the area of creative reasoning in science and technology: the most recent results and achievements about the topics above are illustrated in detail in the papers.
Mobility, data mining and privacy : Geographic knowledge discovery
This book assesses this research frontier from a computer science perspective, investigating the various scientific and technological issues, open problems, and roadmap. The editors manage a research project called GeoPKDD, Geographic Privacy-Aware Knowledge Discovery and Delivery, funded by the EU Commission and involving 40 researchers from 7 countries, and this book tightly integrates and relates their findings in 13 chapters covering all related subjects, including the concepts of movement data and knowledge discovery from movement data; privacy-aware geographic knowledge discovery; wireless network and next-generation mobile technologies; trajectory data models, systems and warehouses; privacy and security aspects of technologies and related regulations; querying, mining and reasoning on spatiotemporal data; and visual analytics methods for movement data.
Misbehaving Proteins : Protein (Mis)Folding, Aggregation, and Stability
Misfoldedaggregatedproteinoncewasconsideredasinterestingasyesterday’strash—a bothersome by-product of important and productive activities, to be disposed of and forgotten as quickly as possible. Yesterday’s trash has become today’s focus of cons- erable scienti?c interest for at least two reasons: (1) protein aggregates are at the core of a number of chronic degenerative diseases such as Alzheimer’s disease, and (2) - gregation poses signi?cant obstacles to the manufacture of safe, ef?cacious, and stable protein products. As interest in protein misfolding, aggregation, and stability has soared beyond the core group of traditional protein-folding scientists, and as substantial scienti?c progress in understanding and controlling protein misfolding has been achieved, the need to summarize the state of the art became manifest. Although there are many excellent texts and edited collections on protein structure and folding, these volumes tend to relegate protein misfolding and aggregation to a minor role. Review articles and books focused on the biological role of protein aggregates in diseases have been published recently.
Microphone Array Signal Processing
Microphone arrays have attracted a lot of interest in the last two decades. The reason behind this is that they have the potential to solve many important problems in both human-machine and human-human interfaces for different kinds of communications. But before microphone arrays can be deployed broadly, there is a strong need for a deep understanding of the problems encountered in the real world and their clear formulation in order that useful algorithms can be developed to process the sensor signals.
Micromanufacturing and Nanotechnology
Micromanufacturing and Nanotechnology is an emerging technological infrastructure and process that involves manufacturing of products and systems at the micro and nano scale levels. Development of micro and nano scale products and systems are underway due to the reason that they are faster, accurate and less expensive. Moreover, the basic functional units of such systems possesses remarkable mechanical, electronic and chemical properties compared to the macro-scale counterparts. Since this infrastructure has already become the prefered choice for the design and development of next generation products and systems it is now necessary to disseminate the conceptual and practical phenomenological know-how in a broader context. This book incorporates a selection of research and development papers. Its scope is the history and background, underlynig design methodology, application domains and recent developments.
Microbiome
Despite the increasing interest of healthy or fat as well sick people in selecting a suitable diet for them, as nutrition is becoming an interesting area recently, in contrast to that we have noticed that there is almost a rare or no interest in Microbiome field in our country by which we can be much more accurate in selecting a diet based on comparing a map of microbiomein healthy person with ill person individually to provide a patient with the right missing food to improve his immune system, or even for a child since birth, to build the best immune system as we compared the benefits of mother’s milk, and artificial one, therefore we will focus in our study on this new science for two reasons the first is to present it and secondly to integrate it in the practice by interested doctors.
MICAI 2008 : Advances in Artificial Intelligence ;7th Mexican International Conference on Artificial Intelligence, Atizapán de Zaragoza, Mexico, October 27-31, 2008 Proceedings
The 96 revised full papers presented together with 2 invited lectures were carefully reviewed and selected from 363 submissions. The papers are organized in topical sections on logic and reasoning, knowledge-based systems, knowledge representation and acquisition, ontologies, natural language processing, machine learning, pattern recognition, data mining, neural networks, genetic algorithms, hybrid intelligent systems, computer vision and image processing, robotics, planning and scheduling, uncertainty and probabilistic reasoning, fuzzy logic, intelligent tutoring systems, multi-agent systems and distributed ai, intelligent organizations, bioinformatics and medical applications, as well as applications.
MICAI 2005 : Advances in Artificial Intelligence ; 4th Mexican International Conference on Artificial Intelligence, Monterrey, Mexico, November 14-18, 2005, Proceedings
Constitutes the refereed proceedings of the 4th Mexican International Conference on Artificial Intelligence, MICAI 2005, held Mexico, in November 2005. This book is organized in topical sections on knowledge representation and management, logic and constraint programming, uncertainty reasoning, multiagent systems and distributed AI, and others.
Methods of Legal Reasoning
The book attempts to describe and criticize four methods used in legal practice, legal dogmatics and legal theory: logic, analysis, argumentation and hermeneutics. Apart from a presentation of basic ideas connected with the above mentioned methods, the essays contained in this book seek to answer questions concerning the assumptions standing behind these methods, the limits of using them and their usefulness in the practice and theory of law. A specific feature of the book is that in one study four different, sometimes competing concepts of legal method are discussed. The panorama, sketched like this, allows one to reflect deeply on the questions concerning the methodological conditioning of legal science and the existence of a unique, specific legal method. The authors argue that there exists no such method.
Metaphor and Analogy in Science Education
This book brings together powerful ideas and new developments from internationally recognised scholars and classroom practitioners to provide theoretical and practical knowledge to inform progress in science education. This is achieved through a series of related chapters reporting research on analogy and metaphor in science education. Throughout the book, contributors not only highlight successful applications of analogies and metaphors, but also foreshadow exciting developments for research and practice. Themes include metaphor and analogy: best practice, as reasoning; for learning; applications in teacher development; in science education research; philosophical and theoretical foundations. Accordingly, the book is likely to appeal to a wide audience of science educators –classroom practitioners, student teachers, teacher educators and researchers.
Messung von Ressourceneffizienz mit der ESSENZ-Methode : Integrierte Methode zur ganzheitlichen Bewertung = Measuring resource efficiency with the ESSENCE method : Integrated method for holistic evaluation
Develops a reliable method for evaluating the use of resources. This is necessary because the strong economic growth of the last decades has led to an intensive use of natural resources. With their increasing use, there are also additional burdens on the environment and restrictions on the availability of resources. For these reasons, efficient use of resources is required as an important contribution to sustainable development.
