الصفحة 2
الصفحة 2
Ondansetron Patches
The objective of this study was to develop the matrix of transdermal drug delivery system (TDDS) of ondansetron hydrochloride (ODH), in which ondansetron is the first serotonin subtype 3 receptor antagonist indicated for the treatment and/or prophylaxis of postoperative, chemotherapy or radiotherapy induced emesis. It has been proven efficient and safe to treat such symptoms, by using in vitro drug release study and evaluate the effect of eucalyptus oil and different percentage of carbopol 940. The result of drug release decreased by increasing the percentage of carbopol 940 which achieved the purpose of the study by prolonging the release of the ondansetron . The patch provides a means to reduce the side effects associated with its oral therapy, avoidence of the first-pass metabolism and minimize inconsistency in absorption across GIT. Various types of transdermal patches are used to incorporate the active ingredients into the circulatory system via skin.
Oncology : An Evidence-Based Approach
Reflect the principles and current practice of oncology with contributors from the fields of medical, surgical, and radiation oncology. The textbook will incorporate an evidence-based approach, enabling the reader to make decisions on the basis of concrete data. Sections on solid tumors, hematologic malignancies and the practice of oncology address the natural history and therapy for the full spectrum of neoplastic diseases in the adult. Further sections present fundamentals of supportive care of the cancer patient, the management of oncologic emergencies and acute toxicities of therapy, as well as care of metastatic disease and the terminally-ill patient. Breaking new ground, the textbook features thoughtful, in-depth sections on cancer prevention and control, cancer surviorship, the economics of cancer care, and cancer informatics. Cancer imaging is covered with an organ system-based approach, with an additional chapter on the especially intriguing potential of PET. Furthermore, a comprehensive section on translational basic science reviews the fundamentals of molecular biology, the cell cycle and signal transduction, carcinogenesis, cancer genetics, the biology of invations and metastasis, and tumor immunology.
Oncogenes Meet Metabolism : From Deregulated Genes to a Broader Understanding of Tumour Physiology
In 1920s, Otto Warburg described the phenomenon of ‘aerobic glycolysis’, the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburg’s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed for most human tumours. With the advent of molecular biology the focus in tumour research has shifted towards the search for oncogenes. However, the interest in cancer molecular profiling eventually led to a renaissance of the Warburg effect trying to combine genetic alterations with effects on metabolism with the help of modern analytic technologies to rapidly analyze broad varieties of metabolites in various tissues and bodyfluids (metabonomics).
Oncofertility : Fertility Preservation for Cancer Survivors
While cancer survival rates have increased steadily over the last several decades, particularly among younger patients, the more aggressive forms of treatment that have made this possible often compromise a cancer patient's ability to later have biological children. In the past, pregnancy after cancer was largely unheard of. Today it is increasingly a possibility due to high survivorship rates in general and emerging reproductive technologies that give patients and their families options at the time of diagnosis to ensure a patient's future fertility (cryopreservation of ovarian tissue).
Once upon a time : illustrations from fairytales, fables, primers, pop-ups, and other children's books
The 1905 obituary of John McLoughlin, Jr., in Publisher's Weekly declared,?Every child in the land knows the McLoughlin books. ... In fact, the history in the last decade of colored toy books for youngsters is the history of Mr. McLoughlin and his firm.?
On the move to meaningful internet systemss 2005 : CoopIS, DOA, and ODBASE ; Vol. 3760 : OTM Confederated International Conferences, CoopIS, DOA, and ODBASE 2005, Agia Napa, Cyprus, October 31 - November 4, 2005, Proceedings Part I
such as the modeling of (legal) regulatory systems and the ubiquitous nature of their usage. Weweregladto seethatin 2005undertheinspiredleadershipofDr. Pilar Herrero, several of earlier successful workshops re-emerged with a second or even third edition (notably WOSE, MIOS-INTEROP and GADA), and that 5 new workshops could be hosted and successfully organized by their respective proposers: AWeSOMe, SWWS, CAMS, ORM and SeBGIS. .
On the move to meaningful internet systems 2007 : OTM 2007 Workshops ; OTM Confederated International Workshops and Posters, AWeSOMe, CAMS, OTM Academy Doctoral Consortium, MONET, OnToContent, ORM, PerSys, PPN, RDDS, SSWS, and SWWS 2007, Vilamoura, Portugal, November 25-30, 2007,
it is clear that there is an acute and increasing need to address and discuss in an integrated forum the implied software and system issues as well as methodological, semantical, theoretical and application issues. As we all know, e-mail, the Internet, and even video conferences are not sufficient for effective and efficient scientific exchange. This is why the OnTheMove (OTM) Federated Conferences series has been created to cover the increasingly wide yet closely connected range of fundamental technologies such as data and Web Semantics.
On the move to meaningful internet systems 2007 : OTM 2007 Workshops ; OTM Confederated International Workshops and Posters, AWeSOMe, CAMS, OTM Academy Doctoral Consortium, MONET, On To Content, ORM, PerSys, PPN, RDDS, SSWS, and SWWS 2007, Vilamoura, Portugal, November 25-30, 2007, Proceedings, Part II
This two-volume set LNCS 4805/4806 constitutes the refereed proceedings of 10 international workshops and papers of the OTM Academy Doctoral Consortium held as part of OTM 2007 in Vilamoura, Portugal, in November 2007. The first volume begins with 23 additional revised short or poster papers of the OTM 2007 main conferences.
On the move to meaningful internet systems 2007 : CoopIS, DOA, ODBASE, GADA, and IS ; OTM Confederated International Conferences, CoopIS, DOA, ODBASE, GADA, and IS 2007, Vilamoura, Portugal, November 25-30, 2007, Proceedings, Part II
This two-volume set LNCS 4803/4804 constitutes the refereed proceedings of the five confederated international conferences on Cooperative Information Systems (CoopIS 2007), Distributed Objects and Applications (DOA 2007), Ontologies, Databases and Applications of Semantics (ODBASE 2007), Grid computing, high performance and Distributed Applications (GADA 2007), and Information Security (IS 2007) held as OTM 2007 in Vilamoura, Portugal, in November 2007.
On the move to meaningful internet systems 2007 : CoopIS, DOA, ODBASE, GADA, and IS ; OTM Confederated International Conferences, CoopIS, DOA, ODBASE, GADA, and IS 2007, Vilamoura, Portugal, November 25-30, 2007, Proceedings, Part I
Constitutes the proceedings of the 5 confederated international conferences on Cooperative Information Systems, Distributed Objects and Applications, Ontologies, Databases and Applications of Semantics, Grid computing, high performance and Distributed Applications, and Information Security held as OTM 2007 in Vilamoura, Portugal, in November 2007.
On the move to meaningful internet systems 2006 : OTM 2006 Workshops ; Vol.4278 ; OTM Confederated International Conferences and Posters, AWeSOMe, CAMS, COMINF ,IS, KSinBIT, MIOS-CIAO, MONET, On To Content, ORM, PerSys, OTM Academy Doctoral Consortium, RDDS,SWWS,SeBGIS 2006, Montpellier, France, October 29 - November 3, 2006, Proceedings, Part II
This two-volume set LNCS 4277/4278 constitutes the refereed proceedings of 14 international workshops held as part of OTM 2006 in Montpellier, France in October/November 2006. The first volume begins with 26 additional revised short or poster papers of the OTM 2006 main conferences.
On the move to meaningful internet systems 2006 : OTM 2006 Workshops ; Vol. 4277 ; OTM Confederated International Conferences and Posters, AWeSOMe, CAMS, COMINF, IS, KSinBIT, MIOS-CIAO, MONET, On To Content, ORM, PerSys, OTM Academy Doctoral Consortium, RDDS, SWWS, SeBGIS 2006, Montpellier, France, October 29 - November 3, 2006, Proceedings, Part I
This two-volume set LNCS 4277/4278 constitutes the refereed proceedings of 14 international workshops held as part of OTM 2006 in Montpellier, France in October/November 2006. The 191 revised full papers presented were carefully reviewed and selected from a total of 493 submissions to the workshops. The first volume begins with 26 additional revised short or poster papers of the OTM 2006 main conferences.
On the move to meaningful internet systems 2006 : CoopIS, DOA, GADA, and ODBASE ; Vol. 4276 ; OTM Confederated International Conferences, CoopIS, DOA, GADA, and ODBASE 2006, Montpellier, France, October 29 - November 3, 2006, Proceedings, Part II
A two-volume set, which constitutes the refereed proceedings of the four confederated conferences CoopIS 2006, DOA 2006, GADA 2006, and ODBASE 2006 held as OTM 2006 in Montpellier, France. It contains 106 revised full and 9 short papers, which were carefully reviewed and selected from a total of 361 submissions.
On the move to meaningful internet systems 2006 : CoopIS, DOA, GADA, and ODBASE ; Vol. 4275 ; OTM Confederated International Conferences, CoopIS, DOA, GADA, and ODBASE 2006, Montpellier, France, October 29 - November 3, 2006, Proceedings, Part I
This two-volume set LNCS 4275/4276 constitutes the refereed proceedings of the four confederated conferences CoopIS 2006, DOA 2006, GADA 2006, and ODBASE 2006 held as OTM 2006 in Montpellier, France in October/November 2006. The 106 revised full and nine short papers presented together with four keynote speeches were carefully reviewed and selected from a total of 361 submissions.
On the move to meaningful internet systems 2005 : OTM 2005 Workshops ; OTM Confederated International Workshops and Posters, AWeSOMe, CAMS, GADA. MIOS+INTEROP, ORM, PhDS, SeBGIS. SWWS. and WOSE 2005, Agia Napa, Cyprus, October 31 - November 4, 2005, Proceedings
This book constitutes the joint refereed proceedings of nine international workshops held as part of OTM 2005 in Agia Napa, Cyprus in October/November 2005.The 145 revised full papers presented were carefully reviewed and selected from a total of 268 submissions. Topics addressed are agents, Web services and ontologies merging (AWeSOMe 2005), context-aware mobile systems (CAMS 2005), grid computing and its application to data analysis (GADA 2005), inter-organizational systems and interoperability of enterprise software and applications (MIOS+INTEROP 2005), object-role modeling (ORM 2005), a PHD symposium (PhDS 2005), semantic-based geographical information systems (SeBGIS 2005), Web semantics (SWWS 2005), and ontologies, semantics and e-learning (WOSE 2005)
On the move to meaningful internet systems : OTM 2008 Workshops ; OTM Confederated International Workshops and Posters, ADI, AWeSoMe, COMBEK, EI2N, IWSSA, MONET, OnToContent + QSI, ORM, PerSys, RDDS, SEMELS, and SWWS 2008, Monterrey, Mexico, November 9-14, 2008. Proceedings
This volume constitutes the refereed proceedings of 13 international workshops held as part of OTM 2008 in Monterrey, Mexico, in November 2008.The 106 revised full papers presented were carefully reviewed and selected from a total of 171 submissions to the workshops. The volume starts with 19 additional revised poster papers of the OTM 2008 main conferences CoopIS and ODBASE. Topics of the workshop papers are ambient data integration (ADI 2008), agents and web services merging in distributed environment (AWeSoMe 2008), community-based evolution of knowledge-intensive systems (COMBEK 2008), enterprise integration, interoperability and networking (EI2N 2008), system/software architectures .
On the Move to Meaningful Internet Systems : OTM 2008 ; OTM 2008 Confederated International Conferences, CoopIS, DOA, GADA, IS, and ODBASE 2008, Monterrey, Mexico, November 9-14, 2008, Proceedings, Part II
This two-volume set LNCS 5331/5332 constitutes the refereed proceedings of the five confederated international conferences on Cooperative Information Systems (CoopIS 2008), Distributed Objects and Applications (DOA 2008), Grid computing, high performAnce and Distributed Applications (GADA 2008), Information Security (IS 2008), and Ontologies, Databases and Applications of Semantics (ODBASE 2008), held as OTM 2008 in Monterrey, Mexico, in November 2008.
On the move to meaningful internet systems : OTM 2008 ; OTM 2008 Confederated International Conferences, CoopIS, DOA, GADA, IS, and ODBASE 2008, Monterrey, Mexico, November 9-14, 2008, Proceedings, Part I
This two-volume set LNCS 5331/5332 constitutes the refereed proceedings of the five confederated international conferences on Cooperative Information Systems (CoopIS 2008), Distributed Objects and Applications (DOA 2008), Grid computing, high performAnce and Distributed Applications (GADA 2008), Information Security (IS 2008), and Ontologies, Databases and Applications of Semantics (ODBASE 2008), held as OTM 2008 in Monterrey, Mexico, in November 2008.
On the Moon : The Apollo Journals
This book explains how the Apollo crews learned to work on the lunar surface. Its lively and informative text draws heavily on transcripts and photographs to illustrate points. It puts the reader on the lunar surface with the astronauts, sharing their observations, excitement, and frustrations.
On the history of the idea of law
On the History of the Idea of Law is the first book ever to trace the development of the philosophical theory of law from its first appearance in Plato's writings to today. Professor Letwin finds important and positive insights and tensions in the theories of Plato
