الصفحة 2
الصفحة 2
Intermittent fasting
The potential benefits of intermittent fasting are not limited to weight loss and weight management. Recent studies have shed light on its role in adaptive cellular responses that reduce oxidative damage and inflammation, optimize energy metabolism and bolster cellular protection. By reprogramming metabolic and stress resistance pathways, intermittent fasting has the possible ability to increase longevity and reduce aging. Studies on animals have given promising result that show how intermittent fasting help prevent and treat diseases like diabetes, cancers, heart disease and neurodegeneration. Major mechanisms hypothesized to link fasting regimens with human health: circadian biology and the gastrointestinal microbiota.
Indigenous pathways, transitions and participation in higher education : From policy to practice
This book brings together contributions by researchers, scholars, policy-makers, practitioners, professionals and citizens who have an interest in or experience of Indigenous pathways and transitions into higher education. University is not for everyone, but a university should be for everyone. To a certain extent, the choice not to participate in higher education should be respected given that there are other avenues and reasons to participate in education and employment that are culturally, socially and/or economically important for society. Those who choose to pursue higher education should do so knowing that there are multiple pathways into higher education and, once there, appropriate support is provided for a successful transition.
Indian Agriculture Towards 2030 : Pathways for Enhancing Farmers’ Income, Nutritional Security and Sustainable Food and Farm Systems
The book comprises of ten contributions. Apart from the overview chapter on transformational change and the concluding chapter on pathways for 2030, there are eight thematic chapters on topics such as transforming Indian agriculture, dietary diversity for nutritive and safe food; climate crisis and risk management; water in agriculture; pests, pandemics, preparedness and biosecurity natural farming; agroecology and biodiverse futures; science, technology and innovation in agriculture; and structural reforms and governance.
Immunology, phenotype first : How mutations have established new principles and pathways in immunology
This monograph deals with the impact of classical genetics in immunology, prov- ing examples of how large immunological questions were solved, and new fields opened to analysis through the study of phenotypes, either spontaneous or induced. As broad as biology has become, there are those who do not fully understand what the genetic approach is, and how it differs fundamentally from most of the methods available to natural scientists.
Hormones, metabolism and the benefits of exercise
The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.
Hormonal carcinogenesis V
Information gathered from cell-free systems, cell cultures, animal models, and human studies, together will (1) provide important insights to our understanding of hormonal cancer causation, development, and prevention; (2) be the primary objective of these Symposia.
Higher Education Landscape 2030 : A Trend Analysis Based on the AHEAD International Horizon Scanning
The digital transformation clearly highlights the role of universities and institutes of higher education in shaping a higher education system that is more open and provides education to everyone who can benefit from it
Heterocyclic Antitumor Antibiotics
Heterocyclic Compounds Includes aspects such as synthesis, reaction mechanisms, structure complexity, properties, reactivity, stability, fundamental and theoretical studies, biology, biomedical studies, pharmacological aspects, applications in material sciences etc. Metabolism will be also included which will provide information useful in designing pharmacologically active agents. Pathways involving destruction of heterocyclic ring will also be dealt with so that synthesis of specifically functionalized non-heterocyclic molecules can be designed. Overall scope is to cover topics dealing with most of the areas of current trends in heterocyclic chemistry which will suit to a larger heterocyclic community.
Handbook of medicinal plants of the world for aging : Botany, ethnopharmacology, natural Products, and molecular pathways
Provides an unprecedented comprehensive overview of more than 100 plants used globally as medicine with the potential to prevent premature aging. It is covers the pathophysiology of aging from the molecular and cellular to the organ levels, as well as the current state of knowledge about the modes of action of natural products from plants on the pathophysiological pathways related to the (i) cardiovascular system and metabolism, (ii) central nervous system, (iii) kidneys, (iv) bones, (v) skin and hair, and (vi) immune system.
Handbook of Behavioral and Emotional Problems in Girls
Psychopathology in children and adolescents has been extensively researched and addressed in terms of its epidemiology, expression, developmental pathways, and causes. And despite all the research studies and findings, the question remained: Are the emotional and behavioral problems of girls unique to the distinct aspects of female development, behavior, and adjustment? To fully understand and address the emotional and behavioral problems of girls, their distinct characteristics must be examined in terms of both developmental progression and context—that is, in terms of their various ethnic, cultural, socioeconomic backgrounds as well as family, school, and peer environments and influences.
Gut orchestra : Micro-symphony turned onco-cacophony
The role of microbiota in colorectal cancer has been studied since alterations in its composition were observed. Ever since, there are more and more pieces of evidence that microbiota could be implicated in colorectal cancer progression. Thus, the components of the microbiota could be biomarkers for the diagnosis and prognosis of colorectal cancer. It is truly important to address how the microbiota interacts with the host and how the host shapes the microbiota, in order to understand the biological pathways and mechanisms involved in their relationship and the consequences of their interactions in colorectal cancer.
Groundwater Recharge from Run-off, Infiltration and Percolation
This book first discusses the recharge fluxes relating both to the quantity and quality of groundwater. In order to face the threats to the water supply and to be able to maintain a sustainable water management policy, detailed knowledge is needed in between others on the surface to subsurface transformation link in the water cycle. Secondly, the presentation and comparison of both the traditional and modern approach to determine groundwater recharge is discussed. The traditional approach to determine groundwater recharge, is based on water balance estimates and hydraulic considerations, which yield instantaneous values at best but do not integrate the totality of recharge pathways in time and space. In contrast, environmental tracers do integrate these factors. Finally, the fate of groundwater recharge in the subsurface by hydraulic and geologic means is discussed in detail, in order to stimulate adapted groundwater management strategies and to better assess consequences of climate changes on groundwater resources as a whole.
Global Pathways to Education : Cultural Spheres, Networks, and International Organizations
The research presented in this volume is a wide-ranging analysis and explanation of the dynamics of emergence, diffusion, and change in relation to state education systems. The chapters offer an empirical investigation into whether the global diffusion of Western-rational educational content and organizational forms occurs as expected by neoinstitutionalist theory, or whether culturally specific developmental paths dominate in different parts of the world.
Geography and Drug Addiction
لإhis book contains drug addiction contributes to better understanding the etiology of addiction, its diffusion, its interaction with geographically variable environmental, social, and economic factors, and the strategies for its treatment and prevention. This book explores links between geography and drug abuse and identifies research ideas, connections, and research pathways which point to some promising avenues for future work in this area
Genetic programming IV : Routine human-competitive machine intelligence
Genetic Programming IV: Routine Human-Competitive Machine Intelligence presents the application of GP to a wide variety of problems involving automated synthesis of controllers, circuits, antennas, genetic networks, and metabolic pathways. The book describes fifteen instances where GP has created an entity that either infringes or duplicates the functionality of a previously patented 20th-century invention, six instances where it has done the same with respect to post-2000 patented inventions, two instances where GP has created a patentable new invention, and thirteen other human-competitive results. The book additionally establishes: GP now delivers routine human-competitive machine intelligence GP is an automated invention machine GP can create general solutions to problems in the form of parameterized topologies GP has delivered qualitatively more substantial results in synchrony with the relentless iteration of Moore's Law
Genetic control of neuronal migrations in human cortical development
Introduction Cortical development is a complex, tightly regulated process that eventually leads to the six-layered adult human neocortex, the substrate of the unique cognitive, emotional, and social abilities of our species. The basic mechanisms of early cortical development are believed to be very similar among mammals, which has led to a tendency of extrapolating experimental data from rodents on humans.
Future-Oriented Technology Analysis : Strategic Intelligence for an Innovative Economy
The application of foresight to address the challenges of uncertainty and rapid change has grown dramatically in the past decade. In that period, the techniques have been greatly refined and the scope has been broadened to encompass future-oriented technology analysis (FTA) and more recently, the concept and practice of strategic intelligence. FTA addresses directly the longer-term future through the active and continuous development of visions, and pathways to realise these visions. It is increasingly seen as a valuable management and policy tool complementing, and extending further into the future, classical strategy, planning, and decision-making approaches.
Future approaches for safe and effective pain management
Pain is defined as an unpleasant sensory and emotional experience that is associated with actual or potential tissue damage or described in terms of such damage. It is subjective and considered an important physiological mechanism by which humans prevent themselves from developing tissue injury. However, pain patients do not respond to treatment in the same way, which makes it challenging to issue a consistent treatment for all pain conditions. Excessive pain can markedly increase psychological health problems and decrease health‐related quality of life; therefore, pain should be managed appropriately by analgesics. Analgesics act in various ways on the peripheral and central pain pathways and are regarded as one of the most valuable but equally dangerous groups of medications. Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined. Pain severities as well as responses to analgesics, can also be very variable among sufferer.
Foundations of Sport-Related Brain Injuries
A major take-home point from this book should be the assumption that symptom resolution does not necessarily mean injury resolution. As can be seen by research focusing on global metabolic cascades and neural activity of the brain, long-standing dysfunctional pathways continue to exist for extended periods of time even after a minor concussion. Until we completely understand the consequences of short-term perturbations and long-term residual brain dysfunctions, concussions must be treated with respect and given a higher priority for continued research activity.
Finding the limits of the limes : Modelling demography, economy and transport on the edge of the Roman Empire
This book demonstrates the application of simulation modelling and network analysis techniques. The book shows the added value of state-of-the-art computer modelling techniques and bridges computational and conventional approaches. Topics that will be of particular interest to archaeologists are the question of (forced) surplus production, the demographic and economic effects of the Roman occupation on the local population, and the structuring of transport networks and settlement patterns. For modellers, issues of sensitivity analysis and validation of modelling results are specifically addressed. This book will appeal to students and researchers working in the computational humanities and social sciences, in particular, archaeology and ancient history.
