الصفحة 2
الصفحة 2
Non-Covalent Multi-Porphyrin Assemblies : Synthesis and Properties
This book presents an overview of the synthesis, structure, and properties of molecules obtained by connecting several porphyrins or metalloporphyrins through a variety of chemical linkages. This handsomely produced book gives the reader a broad introduction to this popular and important field. Much of the work encompassed in this area is inspired by the desire to obtain photochemically responsive molecules capable of mimicking various aspects of photosynthesis… As with many edited volumes of this type, there is a certain amount of duplicate coverage of some topics. Also the focus is largely on the methods used to generate the multiporphyrin arrays, and in some cases less attention is given to the properties, other than the structural properties of these arrays.
Noncommunicable diseases
Focuses on cardiovascular disease, diabetes, cancer and chronic respiratory disease and their five shared main risk factors (tobacco use, harmful use of alcohol, unhealthy diet, physical inactivity and air pollution) as defined by the United Nations, this book provides a synopsis of one of the world’s biggest challenges of the 21st century. NCDs prematurely claim the lives of millions of people across the world every year, with untold suffering to hundreds of millions more, trapping many people in poverty and curtailing economic growth and sustainable development. While resources between and within countries largely differ, the key principles of surveillance, prevention and management apply to all countries, as does the need to focus resources on the most cost-effective and affordable interventions and the need for strong political will, sufficient resources, and sustained and broad partnerships. This compendium consists of 59 short and accessible chapters in six sections: (i) describing and measuring the burden and impact of NCDs / (ii) the burden, epidemiology and priority interventions for individual NCDs / (iii) social determinants and risk factors for NCDs and priority interventions / (iv) global policy / (v) cross-cutting issues / and (vi) stakeholder action.
Nishina Memorial Lectures : Creators of Modern Physics
This volume is a collection of Nishina Memorial Lectures delivered by distinguished physicists during the past 50 years at the invitation of the Nishina Memorial Foundation.
Next-Generation FTTH Passive Optical Networks : Research Towards Unlimited Bandwidth Access
Dense FTTH Passive Optical Networks (PONs) is a cost efficient way to build fibre access, and international standards (G/E-PON) have been already launched, leading to new set of telecom products for mass deployment. However, these systems only make use of less than 1% of the optical bandwidth; thus, relevant research is taking place to maximize the capacity of these systems, with the latest opto-electronic technologies, demonstrating that the huge bandwidth available through the fibre access can be exploited in a cost efficient and reliable manner.
New Trends of Surgery for Cerebral Stroke and its Perioperative Management
In July 2004 specialists in neurosurgery, neuroradiology, neurology and neurointensive care discussed recent trends at the 2nd Swiss Japanese Joint Conference on Cerebral Stroke Surgery, held in Zurich, Switzerland. New concepts were worked out during the conference and are published in this volume. The book starts with the topic intracranial aneurysms, discussing microsurgical and endovascular treatment modalities, as well as new surgical approaches. Further chapters deal with the management of unruptured aneurysms and with subarachnoid hemorrhage. Practical guidelines for vasospasm treatment are given. Together with contributions about arteriovenous malformations and fistulas, cerebral revascularization techniques and surgery related to the intracranial venous system a comprehensive overview about stroke surgery is given with an interdisciplinary approach. The book will be of interest for all specialists involved in therapy of cerebrovascular disease.
New techniques, materials and technologies in dentistry
Encompasses thrilling state-of-the-art techniques, materials and technologies in dentistry. It compiles a series of original articles that include review articles, in vitro studies and clinical studies, presenting the latest developments in this area.
New Political Economy of Exchange Rate Policies and the Enlargement of the Eurozone
This work examines the political economy of exchange-rate policies in the context of the eastward enlargement of the eurozone. The analysis shows that prospective members of the EMU are likely to pass on some of the incurred Maastricht costs of convergence to the current EMU-members. The transmission mechanism is an altered exchange-rate policy that is carried out utilizing a "threaten-thy-neighbour"-strategy. The nature of the arising conflict between current and prospective EMU-members originates from both parties' admitted inclination to complete the enlargement process, complicated by their disinclination to bear the costs. The ensuing moral-hazard behaviour of the CEECs proves to be one of brinkmanship.
New Perspectives in Political Ethnography
Ethnography is uniquely equipped to look microscopically at the foundations of political institutions and their attendant set of practices, just as it is ideally suited to explain why political actors behave the way they do and to identify the causes, processes and outcomes that are part and parcel of political life. The volume, based on a special issue of Qualitative Sociology has a two-fold purpose: to bring politics into the ethnographic literature and of ethnography in studies of politics. The case studies included are based on the research of ethnographers studying the various level of politics in Brazil, Japan, El Salvador, Bosnia, the Philippines, India and the United States. It will be of interest to those in the sociology of politics, political science and those looking for ethnographic research on a global level.
New Narratives in Eighteenth-Century Chemistry : Contributions from the 1st Francis Bacon Workshop, 21-23 April 2005, California Institute of Technology, Pasadena, California
The eighteenth century has long been considered critical for the development of modern chemistry, yet many crucial features of the period remain largely unknown or unexplored, for general accounts--often built around Lavoisier--have remained quite selective. This volume presents new approaches and topics in an attempt to build a richer, fuller, more complex view of chemical work during the period. Themes include "late-phase" alchemy, professionalization, chemical education, and the links and relations between chemistry and pharmacy, medicine, agriculture, and geology.
New Light on Dark Stars : Red Dwarfs, Low-Mass Stars, Brown Stars
There has been very considerable progress in research into low-mass stars, brown dwarfs and extrasolar planets during the past few years, particularly since the fist edtion of this book was published in 2000. In this new edtion the authors present a comprehensive review of both the astrophysical nature of individual red dwarf and brown dwarf stars and their collective statistical properties as an important Galactic stellar population. Chapters dealing with the observational properies of low-mass dwarfs, the stellar mass function and extrasolar planets have been completely revised. Other chapters have been significantly revised and updated as appropriate, including important new material on observational techniques, stellar acivity, the Galactic halo and field star surveys. The authors detail the many discoveries of new brown dwarfs and extrasolar planets made since publication of the first edition of the book and provide a state-of-the-art review of our current knowledge of very low-mass stars, brown dwarfs and extrasolar planets, including both the latest observational results and theoretical work.
New Dimensions of Business Reporting and XBRL
The authors of this book analyse the social and technical nature and role of XBRL in information supply chains and capital markets as well as the XBRL standard and taxonomies. They provide a critical view of XBRL from a research perspective, present different projects in the XBRL area and indicate future directions for XBRL research. Current research questions are taken up and discussed from different perspectives. From a technical point of view, the research spectrum encompasses the internal perspective up to the final user layer. Apart from these technical issues, there are also key socio-technical aspects which are vital to the understanding of XBRL use.
New Aspects of Zirconium Containing Organic Compounds
Metal carbene complexes have made their way from organometallic curiosities to valuable reagents and catalysts. They offer novel synthetic opportunities in carbon-carbon bond formation based on either carbene-centered reactions or on metal-templated processes which makes them indispensable in modern synthetic methodology. The most prominent metal carbenes are now either commercially available or easy to synthesize and handle with modern laboratory techniques. This volume organized in eight chapters written by the leading scientists in the field illustrates the theoretical background, non-classical nucleophilic and cycloaddition patterns, chromium-templated benzannulation and photo-induced reactions, rhodium-catalyzed carbene transfer as well as the principles and applications of olefin metathesis which has coined the progress in synthetic methodology over the past decade. Designed for researchers in academia and industry as well as graduate students it presents the state-of-the-art potential of carbene complexes in modern organic synthesis.
New Approaches to Circle Packing in a Square : With Program Codes
This book summarizes results achieved in solving the circle packing problem over the past few years, providing the reader with a comprehensive view of both theoretical and computational achievements. Typically illustrations of problem solutions are shown, elegantly displaying the results obtained.Beyond the theoretically challenging character of the problem, the solution methods developed in the book also have many practical applications. Direct applications include cutting out congruent two-dimensional objects from an expensive material, or locating points within a square in such a way that the shortest distance between them is maximal.
Neutrophil : Methods and Protocols
Neutrophils, the most abundant white cells in humans, serve as the primary cellular defense against infection. This volume provides a concise set of protocols for assessing basic neutrophil functions and investigating specialized areas in neutrophil biology. Each of the protocols is written by leading researchers in the field and includes hints for success, as well as guidance for troubleshooting. Part I contains overviews of neutrophil biology, function, and disorders. Part II describes commonly used methods to isolate neutrophils from humans and other animal species. Part III details methods for investigating chemotaxis, transmigration, phagocytosis, and bactericidal activity. Part IV includes protocols that measure neutrophil apoptosis, calcium signal transduction, degranulation and detection of cytoplasmic granules, gene expression, transcription factors, and apoptosis. Part V provides multiple assays for measuring production of intracellular and/or extracellular reactive oxygen species, and a method that details use of the cell-free NADPH oxidase assay, an iconic assay for studies of the neutrophil NADPH oxidase. Part VI provides chapters that describe how to analyze formation and function of neutrophil extracellular traps.
Neurotransmitter Transporters
The present volume of the Handbook of Experimental Pharmacology gives a representative survey of the current status of the structure, function, regulation and molecular pharmacology of Neurotransmitter Transporters and aims at providing an overview of insights that were generated in the past 5 years. If the volume serves as both, a useful compendium of current concepts and an inspiring starting point, it will have fulfilled its mission and will be a source for students interested in this emerging field as well as for experienced scientists looking for an update. This volume is the brainchild of the editor-in-chief of the HEP series, Klaus Starke, awe-inspiring to all pharmacologists of younger generations.
Neurology Oral Boards Review : A Concise and Systematic Approach to Clinical Practice
Rapid recall of vast amounts of factual material is the key to success in both the Neurology Oral Board examination and in everyday patient care. In Neurology Oral Boards Review: A Concise and Systematic Approach to Clinical Practice, Eroboghene E. Ubogu offers a comprehensive review of relevant topics and examination strategies needed to pass the American Board of Psychiatry and Neurology (ABPN) Part II (Oral) exam, complete with up-to-date, evidence-based guidelines on diagnosis and management in clinical neurology. The author has written the book specifically to satisfy the requirements of the ABPN, with clinical case vignettes designed to allow the examinee to localize the plausible disease process, to indicate which investigations may help in establishing a diagnosis, to deduce treatment plans, and to make a prognosis, including patient and family counseling. The emergency cases test the ability to think critically when faced with a neurological emergency, putting a premium on resuscitation, patient safety, and rapid high-yield investigations. The general neurology cases reflect the breadth of disorders experienced in hospital and outpatient settings. The author also provides a detailed description of the oral ABPN examination and suggests a study regimen that takes into account the difficulties of allotting time to prepare while in post-residency training or practice.
Neurocutaneous Disorders : Phakomatoses and Hamartoneoplastic Syndromes
Neurocutaneous diseases are a wide group of conditions that affect the nervous system but appear as lesions of the skin. Some of the more common entities have variable forms of expression that can confuse the diagnosis; for the rare conditions it is difficult to find descriptions in the literature. Recent insights into their cellular, biochemical and molecular genetic bases have shown the essential need for a new nosology and updated genotype-phenotype correlations. The book provides an authoritative source of knowledge about these difficult problems and bridges the gap between clinical recognition and the new molecular medicine. The editors, distinguished clinicians and geneticists, assembled an internationally renowned group of collaborators, many of them the experts who first described a particular disorder or established its present accepted definition.
Neurobiology of Human Values
Man has been pondering for centuries over the basis of his own ethical and aesthetic values. Until recent times, such issues were primarily fed by the thinking of philosophers, moralists and theologists, or by the findings of historians or sociologists relating to universality or variations in these values within various populations. Science has avoided this field of investigation within the confines of philosophy. Beyond the temptation to stay away from the field of knowledge science may also have felt itself unconcerned by the study of human values for a simple heuristic reason, namely the lack of tools allowing objective study. For the same reason, researchers tended to avoid the study of feelings or consciousness until, over the past two decades, this became a focus of interest for many neuroscientists
Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders : Novel Strategies for Research and Treatment
Over the past few decades the involvement of neurosteroids in brain function and mental health has attracted much interest, not only from a neuroscience perspective, but also from clinical and therapeutic aspects. In recent years, much of the research has focused on the multifunctional position of neurosteroids in the nervous system. The areas that have been explored, in particular, are the cellular and molecular mechanisms involved in the activity of neurosteroids in the brain, the role of neurosteroids in brain development, neurodegeneration and neuroplasticity, and their pharmacological properties. The large increase in the number of publications highlights this amplified interest in neurosteroids. Over the last 7 years at least 400 papers have been published describing the putative role of neurosteroids in the modulation of basic brain function and in the etiology and treatment of psychiatric and neurological disorders.
Neuroacanthocytosis Syndromes
Neuroacanthocytosis Syndromes is the first comprehensive review of a field that has not yet received the attention it deserves. Affecting the brain as well as the circulating red cells, these multi-system disorders in the past had often been mistaken for Huntington's disease. Recent breakthroughs have now identified the molecular basis of several of these. This volume grew out of the first international scientific meeting ever devoted to neuroacanthocytosis and provides in-depth information about the state of the art. Its thirty chapters were written by the leading authorities in the field to cover the clinical as well as the basic science perspective, including not only molecular genetics but also experimental pharmacology and cell membrane biology, among others. The book vehemently poses the question of how the membrane deformation of circulating red blood cells relates to degeneration of nerve cells in the brain, the basal ganglia, in particular. It provides a wealth of data that will help to solve an intriguing puzzle and ease the suffering of those affected by one of the neuroacanthocytosis syndromes.
