الصفحة 2
الصفحة 2
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Designing with the wind : Climate-derived architecture

This book explores wind-adaptive architectural design blending the parametric design with digital simulations and suggests a novel approach for specific, even extreme conditions, as the first step in creating architecture that can act in response to the nature around. The chapters propose an urban and architectural design that emerges from the specific wind microclimate of the design site and responds to the changes in the ambient wind conditions. The book looks closely at A) the interdisciplinary wind-driven design method for architects, engineers, and urbanists employing open-source software for CFD analysis and B) the tensegrity-membrane adaptive building façades.

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Critical point theory and its applications

The book include extrema, even valued functionals, weak and double linking, sign changing solutions, Morse inequalities, and cohomology groups. The applications described include Hamiltonian systems, Schrödinger equations and systems, jumping nonlinearities, elliptic equations and systems, superlinear problems and beam equations. Many minimax theorems are established without the use of the (PS) compactness condition.

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Counteracting Urban Heat Island Effects in a Global Climate Change Scenario

Urban Heat Islands (UHIs) are a microclimatic phenomenon which manifests as a significant increase in the temperature of cities compared to their surrounding areas. Recently the phenomenon has been enforced by the tendency to climate change and in particular by extreme climate events. This book presents and analyzes the results of a project to develop and apply mitigation and adaptation strategies and measures for counteracting the global urban heat islands phenomenon, supported by the EU’s Central Europe Regional Development Fund.

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Conceptual Modeling of Information Systems

When designing an information system, conceptual modeling is the activity that elicits and describes the general knowledge the system needs to know. This description, called the conceptual schema, is necessary in order to develop an information system.textbook explains in detail the principles of conceptual modeling independently from particular methods and languages and shows how to apply them in real-world projects. It covers all aspects of the engineering process from structural modeling over behavioral modeling to meta-modeling, and completes the presentation with an extensive case study based on the osCommerce system, an online store-management software program freely available under the GNU General Public License. His presentation is based on well-known industry standards like UML and OCL as a particular conceptual modeling language, yet also delivers the basics of the formal logical language background.

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Marine Geochemistry

Since 1980 a considerable amount of scientific research dealing with geochemical processes in marine sediments has been carried out. This textbook summarizes the state of the art in this field of research. The topics comprise the examination of sedimentological and physical properties of the sedimentary solid phase, of pore water and pore water constituents, organic matter as the driving force of most microbiological processes, biotic and abiotic redox reactions, carbonates and stable isotopes as proxies for paleoclimate reconstruction, metal enrichments in ferromanganese nodules and crusts as well as in hot vents and cold seeps on the seafloor. A new chapter describes properties, occurrence and formation of gas hydrates in marine sediments. The textbook ends with a chapter on model conceptions and computer models to quantify processes of early diagenesis.

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Les thérapies ciblées = Targeted therapies

We are at the start of the development of new therapeutic classes, directed against new molecular targets (EGFR, VEGF, IGFR, Rank, etc.) Several diseases such as kidney, colon or breast cancer, GIST, have a natural history now modified thanks to these therapies. This practical book takes stock of the current use of these molecules.

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Lean Business Systems and Beyond ; 1st IFIP TC 5 Advanced Production Management Systems Conference (APMS’2006), Wroclaw, Poland, September 18-20, 2006

Includes : foundations of computer science; software theory and practice; education; computer applications in technology; communication systems; systems modeling and optimization; information systems; computers and society; computer systems technology; security and protection in information processing systems; artificial intelligence; and human-computer interaction.  Proceedings and post-proceedings of referred international conferences in computer science and interdisciplinary fields are featured. 

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Language Policy and Modernity in Southeast Asia : Malaysia, the Philippines, Singapore, and Thailand

This volume considers the ways in which modernity challenges and informs the language policies of various Southeast Asians nations.  Using case studies from Malaysia, the Philippines, Singapore and Thailand, the authors examine language policies that are explicitly articulated either in the form of State constitutions or in the public proclamations of political leaders. Particular attention is paid to the ways in which English, often seen as the language of globalization, impacts the status of indigenous Southeast Asian language.

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Knowledge, practices, and awareness of safety risks associated with antiemetic use: A cross-sectional study

Highlighted a high prevalence of self-medication, with most participants keeping these drugs at home due to their accessibility and low cost. A strong correlation was observed between educational level and awareness; individuals with higher education were more likely to seek professional advice and carefully read drug leaflets. Conversely, lower educational groups and younger participants showed a greater tendency to repeat doses without consultation or rely on home remedies.

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Claude-Nicolas Ledoux : Architecture and uopia in the era of the French revolution

Claude-Nicolas Ledoux (1736-1806) is today regarded as chief representative of French revolutionary architecture. With his extraordinary inventiveness he projected the architectural ideals of his era. Ledoux's influential buildings and projects are presented and interpreted both aesthetically and historically in this book. His best-known projects - the Royal Saltwords of Arc-et-Senans, the tollgates of Paris, the ideal city of Chaux - reveal the architect's allegiance to the principles of antiquity and Renaissance but also illustrate the evolution of his own utopian language. With the French Revolution, Ledoux ceased building as his contemporaries perceived him as a royal architect. He focused on the development of his architectural theory and redefined the vision of the modern architect

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Cancer immunotherapy

Defining Cancer as a disease in which some of the body's cells grow uncontrollably and spread to other parts of the body, making it an enormous medical and economic burden accounting for 9.6 million deaths in 2018. Cancer treatments were being introduced for a long time. The development of specific therapies to treat cancer really depends on the continued discovery of the molecular changes that lead to the malignant progression of human cancers. More and more drugs are being developed to block cancer pathways that lead to impaired growth and survival of cancer cells. In this dissertation, the concept of cellular and immunotherapy of cancer will be discussed briefly, taking into considerations the mechanisms of action, the advantages, challenges and drawbacks of the different types of monoclonal antibodies and CAR T-Cell therapy.

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Building Physics : Heat, Ventilation, Moisture, Light, Sound, Fire, and Urban Microclimate

Presents the theoretical background of building physics, dealing with the evaluation of physical phenomena related to heat transfer and energy use in buildings, water and water vapour transfer in building structures, daylighting and electric lighting of buildings, sound transmission in building structures and protection against noise, the occurrence and spread of fires in buildings and the thermal response of cities. It contains numerical and computational evaluation methods, numerous computational case studies and examples of experimental analyses. The book demonstrates that the considered physical processes affect the quality of living and working comfort in indoor and outdoor environment.

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Bone Resorption

Bone Resorption, the second volume in the series Topics in Bone Biology, deals with the osteoclast, the bone-resorbing cell, its origins, its enzymes, the regulation of osteoclast activity, and structural aspects of bone resorption. Diseases involving osteoclast function are discussed from the genetic viewpoint in two chapters that span transgenic mouse models to human pathology. Another chapter treats diseases of osteoclast function. Because osteoporosis may be considered a disease in which the bone resorption rate exceeds formation, a separate chapter deals with current and potential therapeutic approaches to this widespread disease that affects both men and women. Bone metastases and an analysis of the central role of the osteoclast in this condition are treated in the concluding chapter.

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Biopharmaceutical drug design and development

Biopharmaceutical Drug Design and Development, Second Edition, updates the widely successful first edition, published in 1999. This new, expanded edition investigates the dozens of new biopharmaceutical drugs that have become available since the publication of the first edition. Among the drugs discussed are ones in the categories of monoclonal antibodies for in-vivo use, cytokines, growth factors, enzymes, immunomodulators, thrombolytics, and immonotherapies including vaccines. Additionally, the volume examines new and emerging technologies, such as bioinformatics, DNA microarrays, transgenics, therapeutic gene delivery, stem cells, nucleic acid-based therapeutics, and macromolecular drug delivery. Authors also study pharmacogenetics in the clinic and changes in biologic drug approval at the FDA. Biopharmaceutical Drug Design and Development, Second Edition, is a worthy sequel in the discussion on the dynamic, exciting field of biotechnology.

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Bioclimatic housing : Innovative designs for warm climates

In the search for sustainable architecture, there is growing interest in the relationship between nature and design. In this context, Bioclimatic Housing covers creative, vernacular architecture to present both the theory and practice of innovative, low-energy architecture.The book interweaves the themes of social progress, technological fixes and industry transformation within a discussion of global and country trends, climate types, solutions and technologies. this is a truly international and authoritative work, providing an essential primer for building designers, builders, developers and advanced students in architecture and engineering.

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Atlas of Wisdom Teeth Surgery

This atlas as a guidebook with twenty chapters covers the latest surgical techniques and clinical cases based on procedure-based approach. In this atlas offer detailed, procedure-based instructions, illustrations and approach that demonstrate how to plan for and perform wisdom teeth surgical procedures safely and efficiently.

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Atlas of fallen dust in Kuwait

Serves as an atlas of deposited dust and dust storms in Kuwait in relation to local and global regions. It features a wealth of maps and images of dust storm trajectories in the region, together with detailed descriptions of the chemical and physical properties of fallen dust

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Artificial intelligence techniques in hydrology and water resources management

The sustainable management of water cycles is crucial in the context of climate change and global warming. It involves managing global, regional, and local water cycles, as well as urban, agricultural, and industrial water cycles, to conserve water resources and their relationships with energy, food, microclimates, biodiversity, ecosystem functioning, and anthropogenic activities. Hydrological modeling is indispensable for achieving this goal, as it is essential for water resources management and the mitigation of natural disasters. In recent decades, the application of artificial intelligence (AI) techniques in hydrology and water resources management has led to notable advances. In the face of hydro-geo-meteorological uncertainty, AI approaches have proven to be powerful tools for accurately modeling complex, nonlinear hydrological processes and effectively utilizing various digital and imaging data sources, such as ground gauges, remote sensing tools, and in situ Internet of Things (IoT) devices.

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An introduction to bioanalysis of biopharmaceuticals

Provides a comprehensive review of the fundamental and practical aspects of bioanalytical support and the integral role it plays in the development of safe and efficacious biopharmaceutical drugs with speed and cost-effectiveness. Focuses on a broad range of conventional and emerging biopharmaceutical modalities including monoclonal antibody-based therapeutics, gene therapy, cell therapy, peptides and oligonucleotides.

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