الصفحة 2
الصفحة 2
Micromanufacturing and Nanotechnology
Micromanufacturing and Nanotechnology is an emerging technological infrastructure and process that involves manufacturing of products and systems at the micro and nano scale levels. Development of micro and nano scale products and systems are underway due to the reason that they are faster, accurate and less expensive. Moreover, the basic functional units of such systems possesses remarkable mechanical, electronic and chemical properties compared to the macro-scale counterparts. Since this infrastructure has already become the prefered choice for the design and development of next generation products and systems it is now necessary to disseminate the conceptual and practical phenomenological know-how in a broader context. This book incorporates a selection of research and development papers. Its scope is the history and background, underlynig design methodology, application domains and recent developments.
Metallocenes in Regio- and Stereoselective Synthesis
Metallocene is a well known sandwich complex with two cyclopentadienyl ligands such as ferrocene. Recently, such metallocene compounds have been found to be very characteristic and they have become very important, not only in the area of organic synthesis, but also in polymerization in industry. Metal complexes with one cyclopentadienyl ligand have also become popular as half sandwich complexes. The number of researchers in the field of metallocenes has increased rapidly. However, the origin of the characteristic reactivity of metallocenes is not fully understood. In this volume, the chemistry of metal complexes with at least one cyclopentadienyl ligand is comprehensively covered by leading experts. Reactions discussed here are (i) natural product synthesis, (ii) catalytic asymmetric synthesis, (iii) cyclization reactions, (iv)catalytic reactions, (iv) polymerization reactions and (v) carbon-carbon bond cleavage reactions. The reader will have access to useful information about the current state of metallocene chemistry.
Insecticides Design Using Advanced Technologies
Among the highlights of this book are the use of nanotechnology to increase potency of available insecticides, the use of genetic engineering techniques for controlling insect pests, the development of novel insecticides that bind to unique biochemical receptors, the exploration of natural products as a source for environmentally acceptable insecticides, and the use of insect genomics and cell lines for determining biological and biochemical modes of action of new insecticides.
Inflammation and natural products ; 1st ed.
Brings together research in the area of the natural products and their anti-inflammatory action in medical, nutraceutical and food products, addressing specific chronic inflammatory diseases like cancer and the mechanistic aspects of the mode of action of some key natural products. Inflammation is a complicated process, driven by infection or injury or genetic changes, which results in triggering signalling cascades, activation of transcription factors, gene expression, increased levels of inflammatory enzymes, and release of various oxidants and pro-inflammatory molecules in inflammatory cells. Excessive oxidants and inflammatory mediators have a harmful effect on normal tissue, including toxicity, loss of barrier function, abnormal cell proliferation, inhibiting normal function of tissues and organs and finally leading to systemic disorders. The emerging development of natural product formulations utilizing the unique anti-inflammatory compounds such as polyphenols, polysaccharides, terpenes, fatty acids, proteins and several other bioactive components has shown notable successes.
Immunity boosting medicinal plants of the Western Himalayas
Presents a comprehensive guide to traditional immunity-boosting medicinal plants of the Himalayas, their traditional uses, phytochemistry, pharmacology, diversity, conversation, biotechnology, toxicology, as well as future prospective. All the chapters cover the latest advances in ethnobotany, phytochemistry, biochemistry, and biotechnology.
Ibuprofen : Pharmacology, Therapeutics and Side Effects
Ibuprofen is one of the most successful drugs used worldwide for the treatment of mild to moderate pain and various inflammatory conditions. Over the past 40 years, ibuprofen has been proven to be as safe or even safer and also as effective as the established non-steroidal anti-inflammatory drugs (NSAIDs) and the coxibs. This well-written book reviews the pharmacology, clinical uses and the various adverse effects of Ibuprofen, the disposition and unique modes of action in relation to clinical effects of the drug as well as various formulations. The use of combinations with other drugs (e.g. paracetamol, codeine, caffeine) are critically assessed and the impact of natural products and Chinese Medicines on the safety of ibuprofen.
Herbal bioactive-based drug delivery systems ; 1st ed.
Provides a wide-ranging, in-depth resource for herbal bioactives, including detailed discussion of standardization and regulations. The book first explores specific drug delivery systems such as gastrointestinal, ocular, pulmonary, transdermal, and vaginal and rectal. It then discusses novel applications for nano, cosmetics, nutraceuticals, wound healing and cancer treatment. Finally, there is a section focusing on standardization and regulation which includes an enhancement of properties. This book is an essential resource for pharmacologists, pharmaceutical scientists, material scientists, botanists, and all those interested in natural products and drug delivery systems developments.
Handbook of oleoresins : Extraction, characterization, and applications
This is a snapshot of information on oleoresins—production, composition, properties, applications (medicinal & health properties), and more. It is designed to be a practical tool for the various professionals who develop and market spices and oleoresins
Handbook of nutraceuticals and natural products : Biological, medicinal, and nutritional properties and applications ; 2 Volume set
Describes the preparation techniques and functional uses of nutraceuticals and natural products with a focus on the technologies involved. The book includes coverage of the biological, medicinal, and nutritional properties and applications of functional foods, as well as the advanced technologies used in the extraction and functionalization of nano components and the nanomaterial and nanochemical aspects of the products.
Handbook of medicinal plants of the world for aging : Botany, ethnopharmacology, natural Products, and molecular pathways
Provides an unprecedented comprehensive overview of more than 100 plants used globally as medicine with the potential to prevent premature aging. It is covers the pathophysiology of aging from the molecular and cellular to the organ levels, as well as the current state of knowledge about the modes of action of natural products from plants on the pathophysiological pathways related to the (i) cardiovascular system and metabolism, (ii) central nervous system, (iii) kidneys, (iv) bones, (v) skin and hair, and (vi) immune system.
Gentamicin : Biosynthesis, medicinal applications and potential side effects
Discusses the biosynthesis, medicinal applications and potential side effects of Gentamicin. Topics include Gentamicin used in combination therapy and applied to medicinal materials for clinical applications; use of natural products to enhance the antibiotic activity of Gentamicin and other aminoglycosides; regiospecific Gentamicin functionalization; Gentamicin and particle engineering; and the indications and adverse effects of Gentamicin.
Genome Mapping and Genomics in Arthropods
Mapping of animal genomes has generated huge databases and several new concepts and strategies, which are useful to elucidate origin, evolution and phylogeny. Genetic and physical maps of genomes further provide precise details on chromosomal location, function, expression and regulation of academically and economically important genes. The series "Genome Mapping and Genomics in Animals" provides comprehensive and up-to-date reviews on genomic research on a large variety of selected animal systems, contributed by leading scientists from around the world.Insects and other arthropods, the largest group of animals in number of species, have global impact on agriculture, industry, human health and environment. They are of particular economic importance for food production as pollinators, for natural products like silk and also as pests and parasites. Arthropods covered in this volume include honeybee, bumblebee, the parasitic Jewel Wasp, silkworm, pea aphid, mosquito, Hessian fly and tick.
Fungi as an Alternative Source of Anticancer and Antioxidant
Fungi are an " excellent but underexplored source " for new therapeutic compounds. The limited availability of bioactive principles in plant sources could be surpassed by exploiting the chemical entities in the endophytes fungi . fungi represent a rich source of bioactive metabolite that can manipulated to produce desirable novel analogs. In addition to the active substances that can be extracted from the fungi, so that they are useful in several mechanisms. Exploring and exploiting of metabolites from endophytic in terrestrial, mangrove and marine habitats may provide an avenue for discovery of drug candidates against deadly human disease. This review focuses on the production of antioxidant and anticancer from severa fungi habitats.
Fortschritte der Chemie organischer Naturstoffe 89 = Progress in the chemistry of organic natural products
The volumes of this classic series, now referred to simply as "Zechmeister" after its founder, L. Zechmeister, have appeared under the Springer Imprint ever since the series' inauguration in 1938. The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in his field and provides a comprehensive and up-to-date review of the topic in question. Addressed to biologists, technologists, and chemists alike, the series can be used by the expert as a source of information and literature citations and by the non-expert as a means of orientation in a rapidly developing discipline.
Fortschritte der Chemie organischer Naturstoffe = Progress in the chemistry of organic natural products 88
The volumes of this classic series, now referred to simply as "Zechmeister" after its founder, L. Zechmeister, have appeared under the Springer Imprint ever since the series' inauguration in 1938. The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in his field and provides a comprehensive and up-to-date review of the topic in question. Addressed to biologists, technologists, and chemists alike, the series can be used by the expert as a source of information and literature citations and by the non-expert as a means of orientation in a rapidly developing discipline.
Food preservation and safety of natural products
Food Preservation and Safety of Natural Products addresses the most common causes of food spoilage that create significant loss to global food production while also discussing how food serves as a vehicle for the transmission of pathogenic microorganisms responsible for mild to debilitating health conditions in humans. The book provides essential information for food safety professionals on issues relating to foodborne diseases and offers potential solutions by presenting various methods of incorporating natural products in food production to prevent the spread of foodborne pathogenic organisms. The demand for green consumerism and consumers general distaste for synthetic food additives poses a serious challenge to food safety and preservation. Natural products are used as green and sustainable source of bioactive compounds that can be applied in various fields including food. The use of plant and other natural products in food preservation is on the rise, hence this book reviews microbial mediated food spoilage, foodborne pathogens and food contamination and offers applications of natural products in food preservation.
Ethnobotany : A phytochemical perspective
Explores the chemistry behind hundreds of plant medicines, dyes, fibers, flavors, poisons, insect repellants, and many other uses of botanicals. Bridging the gap between ethnobotany and chemistry, this book presents an introduction to botany, ethnobotany, and phytochemistry to clearly join these fields of study and highlight their importance in the discovery of botanical uses in modern industry and research. Part I. Ethnobotany, explores the history of plant exploration, current issues such as conservation and intellectual property rights, and a review of plant anatomy. An extensive section on plant taxonomy highlights particularly influential and economically important plants from across the plant kingdom. Part II. Phytochemistry, provides fundamentals of secondary metabolism, includes line drawings of biosynthetic pathways and chemical structures, and describes traditional and modern methods of plant extraction and analysis. The last section is devoted to the history of native plants and people and case studies on plants that changed the course of human history from five geographical regions: Africa, the Americas, Asia, Europe, and Ocean. Throughout the entire book, vivid color photographs bring science to life, capturing the essence of human botanical knowledge and the beauty of the plant kingdom.
Environmental and Microbial Relationships
After the publication of Volume IV in 1997, the introduction of molecular methods into ecology led to significant new findings. Emphasizing these advances, the chapters for the second edition have been completely updated and revised. This volume provides insight into current research on fungal populations and communities. It focuses on fungal responses to the physical environment, interactions with other fungi, microorganisms and invertebrates, the role of fungi in ecosystem processes such as decomposition and nutrient cycling, and aspects of biogeography and conservation. Several chapters deal with various applications in, e.g. biological pest control, natural products discovery, and the degradation of toxic organic compounds. This is an invaluable source of information both for scientists who wish to update their knowledge of current progress and for graduate students interested in obtaining a first overview of this field of research.
Efficiency in Natural Product Total Synthesis
Uniting the key organic topics of total synthesis and efficient synthetic methodologies, this book clearly overviews synthetic strategies and tactics applied in total synthesis, demonstrating how the total synthesis of natural products enables scientific and drug discovery. • Focuses on efficiency, a fundamental and important issue in natural products synthesis that makes natural product synthesis a powerful tool in biological and pharmaceutical science • Describes new methods like organocatalysis, multicomponent and cascade reactions, and biomimetic synthesis
Curcumin : clinical uses, health effects and potential complications
Curcumin is a natural product with polyphenolic structure. It is used in therapeutic remedies alone or in combination with other natural substances. Many researchers are investigating it because of its biological activities such as: anti-inflammatory, anti-cancer, anti-protozoal, anti-viral, anti-bacterial and has been found to be effective for treatment of Alzheimer, depression, headaches, fibromyalgia, leprosy, fever, menstrual problems, water retention, worms and kidney problems etc. It is an active ingredient in dietary spice, turmeric. It has reactive functional groups: a diketone moiety and two phenolic groups. Despite its unique biological activities, it suffers from some shortcomings which include: gastrointestinal problems, poor bioavailability due to its poor absorption, short half-life, poor solubility in aqueous solutions, rapid systemic elimination and antithrombotic activity which can interfere with blood clotting. The first chapter of this book reviews the different delivery systems used for incorporation of curcumin and its derivatives, release kinetics and up to date in vivo results. Chapter two discusses curcumin nano and microencapsulation and its implications on clinical uses.
