الصفحة 2
الصفحة 2
ESR Spectroscopy in Membrane Biophysics
Membrane proteins offer the greatest challenge in structural biology, and there is an urgent need to develop and apply new biophysical methodologies that are able to generate detailed structural information. Among modern biophysical techniques, site-directed spin-labeling electron spin resonance (SDSL-ESR) appears to show the highest potential to further develop the field. The objective of this book is to provide in-depth information about new advances of SDSL-ESR in membrane biophysics, emphasizing recent developments in the application to membrane proteins.
Diffusion in Condensed Matter : Methods, Materials, Models
Diffusion as the process of particle transport due to stochastic movement is a phenomenon of crucial relevance for a large variety of processes and materials. This comprehensive, handbook-style survey of diffusion in condensed matter gives detailed insight into diffusion as the process of particle transport due to stochastic movement. Leading experts in the field describe in 23 chapters the different aspects of diffusion, covering microscopic and macroscopic experimental techniques and exemplary results for various classes of solids, liquids and interfaces as well as several theoretical concepts and models. Students and scientists in physics, chemistry, materials science, and biology will benefit from this detailed compilation.
Logic Programming and Nonmonotonic Reasoning ; 9th International Conference, LPNMR 2007, Tempe, AZ, USA, May 15-17, 2007, Proceedings
This book constitutes the refereed proceedings of the 9th International Conference on Logic Programming and Nonmonotonic Reasoning, LPNMR 2007, held in Tempe, AZ, USA, May 2007.
Logic Programming and Nonmonotonic Reasoning ; 8th International Conference, LPNMR 2005, Diamante, Italy, September 5-8, 2005, Proceedings
Thesearetheproceedingsofthe8thInternational Conference on Logic Progr- mingandNonmonotonicReasoning (LPNMR2005).Followingthepreviousones held in Washington, DC, USA (1991), Lisbon, Portugal (1993), Lexington, KY, USA(1995), Dagstuhl, Germany(1997), ElPaso, TX, USA(1999), Vienna, A- tria (2001) and Ft. Lauderdale, FL, USA (2004), the eighth conference was held in Diamante, Italy, from 5th to 8th of September 2005. TheaimoftheLPNMRconferencesistobringtogetherandfacilitateinter- tions between active researchers interested in all aspects concerning declarative logic programming, nonmonotonic reasoning, knowledge representation, and the design of logic-based systems and database systems. LPNMR strives to enc- pass theoretical and experimental studies that lead to the implementation of practi...
Liver MRI : Correlation with other Imaging Modalities and Histopathology
In this seminal manuscript the - thor described a new imaging technique which moved the single dimension of NMR spectroscopy to the dual dimension of spatial orientation, thereby resulting in the foundation of modern magnetic re- nance (MR) imaging. Over the ensuing years, MR imaging has assumed an increasingly important role in clinical imaging. It distinguishes itself from other imaging modalities, such as ultrasound (US) or computed tomography (CT), by the unique ability to visualize specific tissue components in a non-- vasive manner. In the earlier days, diagnostic MR imaging was limited to cerebral and musculoskeletal diseases. - aging of other areas which are more prone to movement through breathing (abdominal) or pulsation motions (cardiac) became available more recently, with the introduction of faster sequences and the - velopment of more dedicated MR imaging coils.
LACAME 2004 ; Proceedings of the 9th Latin American Conference on the Applications of the Mössbauer Effect, (LACAME 2004) held in Mexico City, Mexico, 19-24 September 2004
Proceedings of the 9th Latin American Conference on the Applications of the Mössbauer Effect, LACAME 2004, held in Mexico City, Mexico, 19-24 September 2004. Researchers and graduate students interested in the Mössbauer Effect and its applications will find this volume indispensable. The volume presents the most recent developments in the methodology of Mössbauer spectroscopy.
KRAS : Methods and protocols
Details protocols ranging from high yield production metabolically labeled KRAS for NMR studies to approaches that quantify engagement of novel molecules that bind KRAS in live cells. Chapters focus on protein production and characterization, biochemical assays, cell-based assays, KRAS-membrane interactions, targeting KRAS, and cell models.
Computational and Instrumental Methods in EPR
This volume is devoted to both instrumentation and computation aspects of EPR, while addressing applications such as spin relaxation time measurements, the measurement of hyperfine interaction parameters, and the recovery of Mn(II) spin Hamiltonian parameters via spectral simulation.
Characterization II
Molecular Sieves - Science and Technology covers, in a comprehensive manner, the science and technology of zeolites and all related microporous and mesoporous materials. Authored by renowned experts, the contributions to this handbook-like series are grouped together topically in such a way that each volume deals with a specific sub-field. Volume 5 complements Volume 4 (Characterization I) in that it is devoted to the characterization of molecular sieves by a variety of non-spectroscopic techniques (Characterization II). Thus, Volume 5 comprises Chemical Analysis, Thermal Analysis, Pore-Size Characterization by Molecular Probes, Characterization by 129Xe NMR, Coke Characterization, Synthesis and Characterization of Isomorphously Substituted Molecular Sieves.
Bioactive Confirmation II
Specific binding of a ligand to a receptor is a key step in a variety of biol- ical processes, such as immune reactions, enzyme cascades, or intracellular transport processes. The ligand-receptor terminology implies that the rec- tor molecule is signi?cantly larger than the ligand, and the term "bioactive conformation" usually characterizes the conformation of a ligand when it is bound to a receptor. In a more general sense, bioactive conformation applies toanymoleculeinabiologicallyrelevantboundstateregardlessofsizecons- erations. Mostofthecontributions tothisbookaddressligandsthat aremuch smaller than their receptors. X-ray crystallography and high resolution NMR spectroscopy are the two main experimental techniques used to study bioactive conformations. The- fore, the twovolumes ofthisbookcover approachesthat use either ofthetwo techniques, or a combination thereof.
Applied biophysics for drug discovery
It is a guide to new techniques and approaches to identifying and characterizing small molecules in early drug discovery. Biophysical methods are reasserting their utility in drug discovery and through a combination of the rise of fragment-based drug discovery and an increased focus on more nuanced characterisation of small molecule binding, these methods are playing an increasing role in discovery campaigns.
Acidity and Basicity
This is the first handbook on zeolites and other microporous materials. It is an up-to-date, highly sophisticated collection of information for those who deal with zeolites in industry or at academic institutions as well as being a guide for newcomers.
