الصفحة 2
الصفحة 2
Community-Acquired Pneumonia
Community-acquired pneumonia (CAP) is a disease associated with high morbidity and mortality, with at least one third of cases requiring hospitalization, exceeding the numbers admitted for myocardial infarction and stroke. Despite a broad armamentarium of antimicrobials available, it remains an important cause of death in industrialized countries. CAP is caused by a variety of pathogens with their order of importance dependent on the location and population studied. Despite the importance of CAP, reliable data and a recommended evidence-based therapy are lacking, and basic research must be improved. The goal of this volume is to present state-of-the-art knowledge on epidemiology, clinical presentation, immunology, pathology, and diagnosis including the identification of "new pathogens". Therapeutic approaches, antibiotics resistance, disease management and vaccination strategies are also covered. The volume is of interest to researchers and clinicians in virology, epidemiology and biomedicine.
Chemotherapy and pharmacology for leukemia in pregnancy : Guidelines and strategies for best practices
The book addresses a broad range of subjects, including: pregnancy and its characteristics; staging, pathology, morbidity and what to expect in each type of leukemia; chemotherapy for leukemia in pregnant women with complete trials; dose adjustment of chemotherapy for leukemia in pregnancy based on serum dosages; and pharmacokinetics and pharmacodynamics for this unique group of patients. In turn, subsequent chapters focus on protecting the fetus and neonatal management regarding chemotherapy for leukemia in pregnancy, including the treatment and risks for the fetus (for each type of leukemia), intrathecal therapy and its effects on the fetus; supportive drugs, antibiotics and antifungals for pregnant patients during chemotherapy, including intervention and dose adjustments; palliative care for women with leukemia in pregnancy; breastfeeding during treatment for leukemia; pharmacological aspects of supplements, vitamins and nutrition in pregnancy during leukemia treatment; and more.
Cell Signaling in Vascular Inflammation
Although inflammatory disease of the vascular bed of the lung is a major cause of morbidity and mortality in both adult and pediatric age groups, the importance of vascular biology to its understanding, and in developing novel therapeutics, has been overlooked. In Cell Signaling in Vascular Inflammation, leading basic and clinical researchers review the signal transduction mechanisms responsible for lung inflammation, including vascular hyperpermeability, white cell accumulation, and vascular remodeling. The authors cut across disciplines to bring together a broad-based presentation of inflammatory challenge, both in the initial phases of the inflammatory response, as well as in the more prolonged phase of genomic involvement.
Cell Motility in Cancer Invasion and Metastasis
Cancer Morbidity and mortality result from invasive and metastatic spread. Currently, no therapies are aimed at the underlying mechanisms that enable this progression due to only nascent recognition of the distinct biology which occurs only during tumor dissemination. Recent advances have highlighted the central role of cell motility during the dynamic and transient process of tumor invasion and metastasis. This book includes state-of-the-art updates by international leaders in these studies. Chapters first present the novel model systems that enable new investigations and insights. Chapters then describe in depth the key processes and molecules that may be therapeutically targeted. Finally, the role of cell motility and its signals is explored in a number of key tumor types. This compilation should be useful to researchers in basic and translational oncology as well as those developing novel agents to prevent tumor invasion and metastasis.
Cancer Chemoprevention ; Vol.2 : Strategies for Cancer Chemoprevention
In Cancer Chemoprevention, Volume 2: Strategies for Cancer Chemoprevention, leading chemopreventives investigators comprehensively describe the exciting methodologies that are accelerating progress in the chemoprevention field and review the state of clinical development of preventive agents in the major human cancer target organs. The authors provide sound guidelines for cancer chemopreventive drug development, detailing general strategies and methods for drug discovery, preclinical efficacy, characterization of precancers, safety evaluation of clinical cohorts, and clinical trial design.
Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics
In this newly updated second edition of Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics, William B. White, MD, and a panel of highly distinguished clinicians give a critical review of every aspect of the evaluation of high blood pressure. This includes home and ambulatory blood pressure monitoring, the relationship between whole-day blood pressure and the cardiovascular disease process, and the effects of antihypertensive therapies on these blood pressure parameters. World-class contributors describe the significant advances in our understanding of the circadian pathophysiology of cardiovascular disorders and demonstrate that ambulatory blood pressure values are independent predictors of cardiovascular morbidity and mortality.
Bipolar disorder
Mood" is defined as a ubiquitous and sustained feeling or emotion that dominates a person’s behavior and affects his perception. Mood disorders also known as affective disorders include unipolar and bipolar disorders. Manic-depressive disorder--more contemporarily identified as bipolar disorder (BD)--is a chronic and complex disorder of mood that is characterized by a combination of manic, hypomanic, and depressive episodes, with subsyndromal symptoms extant in between the mood episodes. It is one of the leading causes of worldwide disability and morbidity.
Biological Basis of Geriatric Oncology
Biological Basis of Geriatric Oncology highlights research issues that are specific to geriatric oncology in the field of carcinogenesis and cancer prevention and treatment, based on the biologic interactions of cancer and age. It illustrates the benefit of the principles of geriatrics in the management of cancer in the older individual.
Anxiety in health behaviors and physical illness
While the links between physical illness and depression have been well-documented and analyzed, little has been made of the data relating physical illness to anxiety—until now. Anxiety in Health Behavior and Physical Illness explores complex relationships between medical and anxiety pathology on the theoretical, research, and practical fronts. Over forty experts examine reciprocal roles of anxiety and medical illness as causal or exacerbating factors in each other’s onset and development, describe forms of anxiety typical to major disease entities, discuss common health behaviors as they impact anxiety, recast anxiety disorders as chronic illness, and identify patients for whom new forms of treatment may be warranted.
Anxiety and substance use disorders : The vicious cycle of comorbidity
Anxiety and Substance Use Disorders: The Vicious Cycle of Comorbidity addresses this gap with dispatches from the frontlines of research and treatment. Thirty-four international experts offer findings, theories, and intervention strategies for this common form of dual disorder both across types of substances (alcohol, tobacco, street and prescription drugs) and the range of anxiety disorders (PTSD, social phobia, panic disorder, OCD) to give the reader comprehensive knowledge in a practical format. Informed by the reciprocal relationship between the two types of disorders
Anti-phospholipid Syndrome
APS is an autoimmune disorder characterized by an increased tendency to form abnormal blood clots and Obstetrical morbidity wish cause to multi- miscarriages for women having this syndrome. Patients with Anti-Phospholipid Syndrome usually treated with multidrug regime depending mainly on Anticoagulant drugs, Anti Platelet Drugs and Immunomodulators Drugs. We aim in this project to talk about the Anti-Phospholipid Syndrome, what is patients’ symptoms, how is this disease diagnosed, and what drugs used in treatment and some information about the drug used in the treatment.
Antibiotic prescribing pattern for patients with community-acquired pneumonia in Syrian hospitals
Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality worldwide. The clinical presentation of CAP varies, ranging from mild pneumonia characterized by fever and productive cough to severe pneumonia characterized by respiratory distress and sepsis.Antibiotics are essential for CAP treatment, whereas inappropriate use of antibiotics might lead to increase in resistant bacteria and treatment failure
Anthropologies of Global Maternal and Reproductive Health : From Policy Spaces to Sites of Practice
This open access edited book brings together new research on the mechanisms by which maternal and reproductive health policies are formed and implemented in diverse locales around the world, from global policy spaces to sites of practice. The authors – both internationally respected anthropologists and new voices – demonstrate the value of ethnography and the utility of reproduction as a lens through which to generate rich insights into professionals’ and lay people’s intimate encounters with policy.
