الصفحة 2
الصفحة 2
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New Drug Development for Known and Emerging Viruses

This book discusses the entire field of antiviral drug discovery and development from a medicinal chemistry perspective, focusing on antiviral drugs, targets, and viral disease mechanisms. It provides an outlook on emerging pathogens such as Ebola, Zika, West Nile, Lassa, and includes a chapter on SARS Coronoavirus-2 causing the present pandemic.

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New Challenges in Superconductivity : Experimental Advances and Emerging Theories ; Proceedings of the NATO Advanced Research Workshop, held in Miami, Florida, 11-14 January 2004

This volume contains the proceedings of the 2004 University of Miami Workshop on Unconventional Superconductivity. The workshop was the fourth in a series of successful meetings on High-T Superconductivity and C related topics, which took place at the James L. Knight Physics Building on the University of Miami campus in Coral Gables, Florida, in January 1991, 1995, 1999, and 2004. The workshop consisted of two consecutive events: 1. NATO Advanced Research Workshop (ARW) on New Challenges in Superconductivity: Experimental Advances and Emerging Theories, held on January 11-14, 2004; 2. Symposium on Emerging Mechanisms for High Temperature Superconductivity (SEMHTS), held on January 15-16, 2004.

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New approach to deal with fibromyalgia

You must have walked once among the colorful fields of flowers, enjoying their colors, aromas and touches, but have you ever thought that these beautiful creatures could contain many constituents that have healing properties and be one day a part of your therapy ! Aromatherapy is a holistic healing treatment that uses natural plant extracts to promote health and well-being; it is used in the management of many diseases including a very common syndrome nowadays: Acute or chronic stress/ pain in localized body spots may trigger or aggravate symptoms knowon as fibromyalgia (FM). In this research we're going to discuss this syndrome which is very widespread, but rarely well-diagnosed and associated with many complex and unclear mechanisms. A new approach to deal with FM will be introduced to you subsequently.

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Neurotransmitter Interactions and Cognitive Function

Cognitive function involves the participation of many different neurotransmitter systems in a variety of brain areas. The centerpiece of investigation regarding cognitive function has classically been the cholinergic system, but it has become increasingly clear that other transmitter systems interact with cholinergic systems to provide the neural basis for cognitive function. This book brings together cutting edge research to determine how the transmitter interactions form the mechanistic bases for attention, learning and memory. This research on transmitter interactions not only provides a more accurate, though complex, picture of how the brain works to provide cognitive function, it also provides important new levels of understanding about the mechanisms of cognitive dysfunction and novel avenues for therapeutic treatment. The researchers who contributed to this volume both reviewed the latest findings but also point to the directions of advancement of the field of neurotransmitter interactions and cognitive function.

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Neuroscience in Medicine

This up-to-date edition alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment.

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Neuropsychiatric Disorders : An Integrative Approach

This multidisciplinary book includes current research papers and reviews in the areas of basic neuroscience, neural mechanisms underlying neurodegenerative disorders. It further includes new approaches for neuroprotective treatments, clinical, neurobiological and treatment aspects of psychiatric disorders. The book was conceived as a celebration of the professional life and work of Peter Riederer to mark the occasion of his retirement.

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Neuroprotection : Method and protocols

Contains cutting-edge molecular biology methods on neuroprotective mechanisms and specific preclinical models of the CNS injury, iseases and planning translation. Chapters guide readers through neuropathology, neuroprotection, Alzheimer’s disease, amyotrophic lateral sclerosis, ALS, Huntington’s disease , multiple sclerosis, Parkinson’s disease, spinal cord injury, traumatic brain injury, and ischemic brain injury. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Neuro–Fuzzy Associative Machinery for Comprehensive Brain and Cognition Modelling

Neuro–Fuzzy Associative Machinery for Comprehensive Brain and Cognition Modelling" is a graduate–level monographic textbook. It represents a comprehensive introduction into both conceptual and rigorous brain and cognition modelling. It is devoted to understanding, prediction and control of the fundamental mechanisms of brain functioning. The reader will be provided with a scientific tool enabling him to perform a competitive research in brain and cognition modelling.

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NEURO-COVID-19 : Neuroinvasive potential and neurological complications of SARS-CoV-2

From the earliest days of the COVID-19 pandemic, there have been reports of significant neurological and psychological symptoms following SARS-CoV-2 infection. This research paper is designed to examine the potential psychoneuroendocrine pathogenic mechanisms by which SARS-CoV-2 elicits psychiatric sequelae, as well as to posit potential pharmacologic strategies to address and reverse these pathologies. Following a brief overview of the presence and prevalence of neuropsychiatric manifestation in COVID-19 patients, we address mechanisms by which SARS-CoV-2 could enter or otherwise elicit changes in the CNS.

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Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders : Novel Strategies for Research and Treatment

Over the past few decades the involvement of neurosteroids in brain function and mental health has attracted much interest, not only from a neuroscience perspective, but also from clinical and therapeutic aspects. In recent years, much of the research has focused on the multifunctional position of neurosteroids in the nervous system. The areas that have been explored, in particular, are the cellular and molecular mechanisms involved in the activity of neurosteroids in the brain, the role of neurosteroids in brain development, neurodegeneration and neuroplasticity, and their pharmacological properties. The large increase in the number of publications highlights this amplified interest in neurosteroids. Over the last 7 years at least 400 papers have been published describing the putative role of neurosteroids in the modulation of basic brain function and in the etiology and treatment of psychiatric and neurological disorders.

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Neuroacanthocytosis Syndromes II

Awareness of neuroacanthocytosis disorders has increased significantly in recent years. There have been a number of important developments in the field since the publication of the first volume, Neuroacanthocytosis Syndromes. This book contains the latest research in this area. Recent advances have identified the range of mutations in the causative genes, shedding light on potential phenotype­genotype correlations. Studies of the proteins affected in these disorders have resulted in increased understanding of their functions and distribution. In vitro studies have identified potential protein interactions, which have important implications for pathophysiology. Work on erythrocyte membranes suggests mechanisms for the generation of acanthocytes. Animal models are being generated which will greatly facilitate understanding the role of gene mutations in humans, and provide the foundation for possible therapeutic interventions. In addition, advances in other neurodegenerative disorders, such as Huntington’s and Parkinson’s diseases, have implications for neuroacanthocytosis.

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Neural Preprocessing and Control of Reactive Walking Machines: Towards Versatile Artificial Perception-Action Systems

This book presents biologically inspired walking machines interacting with their physical environment. It describes how the designs of the morphology and the behavior control of walking machines can benefit from biological studies. The purpose of this book is to develop a modular structure of neural control generating different reactive behaviors of the physical walking machines, to analyze the neural mechanisms underlying the reactive behaviors, and to demonstrate the sensor fusion technique leading to smooth switching between appropriate behaviors, like obstacle avoidance and sound tropism.

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Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity

This comprehensive volume, written by experts in the integrative fields of neuroscience, endocrinology and immunology, provides insight into the mechanisms by which neural and neuroendocrine factors influence susceptibility to infection and autoimmunity. The book focuses on multiple sclerosis as the prototypic autoimmune disease and discusses infectious diseases including anthrax, influenza virus, herpes virus and human immunodeficiency virus. The effects of stress on experimental models of multiple sclerosis and also clinical observations of stress in multiple sclerosis patients are discussed. Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity is an ideal book for researches and professionals in the fields of immunology, neuroscience, infectious disease, psychology, microbiology, virology, public health and pharmaceutical sciences.

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Natural Resistance Mechanisms of Plants to Viruses

Resistance phenomena such as the local lesion response, induced resistance, "green islands" and resistance in various crop plants are linked with new information on gene-silencing mechanisms, gene silencing suppressors, movement proteins and plasmodesmatal gating, downstream signalling components, and more.

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Natural anti-aging skin care

Ageing is a natural phenomenon which is a fold, ridge and crease in the skin that occurs due to loss of body mass, poor hydration, disintegration of dermis and epidermis junction. The Skin ageing process involves many changes that occur due to the combination of both endogenous factors and exogenous factors. The ageing of the skin occurs due to various mechanisms like glycation, free radical, cell cycle, and cellular and molecular mechanism of skin ageing. In this review article, we have discussed the treatment, worldwide newer therapies and marketed formulation that are currently available for the reduction of skin ageing.

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Nanotechnology based cosmetics

Explores the applications and advantages of nanotechnology-based cosmetic products compared to conventional formulations. It examines the principles and mechanisms of nanotechnology in enhancing cosmetic product efficacy, delivery, and performance. Key applications covered include nanoparticles for sunscreens, nanoencapsulation for controlled release, nanoemulsions, liposomes for targeted delivery, and antimicrobial nanoparticles. Analyzes case studies from major international cosmetic companies utilizing nanotechnology. It also discusses challenges like safety concerns, potential toxicity, regulations, labeling, consumer awareness, and environmental impact.

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Name Reactions : A Collection of Detailed Mechanisms and Synthetic Applications

The third edition contains major improvements over the previous edition. In addition to updated references, each reaction is now supplemented with two to three representative examples in synthesis to showcase its synthetic utility. Biographical sketches for the chemists who discovered or developed those name reactions have been included. Furthemore, the subject index is significantly expanded.This is an excellent book for arrow pushing and learning organic name reactions as encountered in graduate school .

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Myosins : A Superfamily of Molecular Motors

Application of state-of-the-art cellular and molecular biological, structural biological, genetic, biochemical and biophysical techniques has provided and continues to provide critical information regarding the structure–function relationship; and the cellular roles of various myosins in organisms as diverse as protozoa, yeast, plants and higher animals. The association of myosins with diseases including neurological disorders, immu- deficiencies, cardiomyopathies, hearing and vision loss testify to the importance of understanding the biochemical properties and cellular roles of myosins. The 16 chapters in this volume summarize the tremendous progress made in studying members of the myosin superfamily in recent years and offer critical insight into what future research will yield.

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Myocardial Ischemia : From Mechanisms to Therapeutic Potentials

This book is meant to bridge the gap between original literature and textbook reviews. It brings together investigators of various backgrounds who share their expertise in the biology of myocardial ischemia. Each chapter is a self-contained mini-review, but it will soon become apparent to the reader that there is also a common thread: Molecular and cellular cardiology has never been more exciting than now, but ever more exciting times are yet to come.

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Myelodysplastic Syndromes

This book summarizes our current knowledge of MDS, from very basic aspects to the clinical management. It provides guidance to the diagnosis, an understanding of disease mechanisms, and a discussion of treatment strategies.

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