الصفحة 2
الصفحة 2
Inflammation in the Pathogenesis of Chronic Diseases : The COX-2 Controversy
In this book, a worldwide panel of leading experts discuss the role of inflammation in the pathogenesis of major chronic diseases and the current controversy regarding risk versus benefit of selective cyclooxygenase-2 (COX-2) inhibitors.
Immediate Early Genes in Sensory Processing, Cognitive Performance and Neurological Disorders
This book reviews and details experiments and theories that challenge the reader to expand their view on how IEG research is currently being used to advance our understanding of static and active brain circuits, enabling the processing, acquisition and storage of new information in healthy systems. In addition, we explore roles of IEGs in clinical neuropathology, with potential utility in molecular modeling, to highlight, on a go-forward basis, candidate mechanisms for novel targets in clinical intervention.
Hypoplastic Left Heart Syndrome
Hypoplastic Left Heart Syndrome draws together the experiences of the leading experts in the field. Through their work in all aspects of congenital cardiac care, they have become acknowledged as the world leaders in the diagnostic, medical and social needs of children born with hypoplasia of the left heart. More importantly, for the first time the book recognizes the crucial contributions made by the families of these children. Diagnostic possibilities, options for medical and surgical treatment and a history of their evolution are looked into and the book also gives an insight into the longer-term effects that treatment has on the child and its family. As well as including contributions from medical clinicians, nurses, and psychologists, for the first time a forum is provided for the parents, who have complemented the contributions from the medical and nursing experts to provide a holistic view of the lives and experiences of the children born with this condition. No other publication, currently available, offers such a comprehensive overview of the care required by a child with hypoplasia of the left heart. This book provides the ultimate reference for anyone treating children with this heart condition, particularly paediatric cardiac clinical and nursing teams, radiologists and radiographers, obstetric medical and nursing teams, psychologists, pathologists, geneticists and workers in social care.
How Ficta Follow Fiction : A Syncretistic Account of Fictional Entities
This book presents a novel theory of fictional entities which is syncretistic insofar as it integrates the work of previous authors. It puts forward a new metaphysical conception of the nature of these entities, according to which a fictional entity is a compound entity built up from both a make-believe theoretical element and a set theoretical element. The fictional entity is constructed by imagining the existence of an individual with certain properties and adding a set-theoretical element consisting of the set of properties corresponding to the properties of the imagined entity.
High Field Brain MRI : Use in Clinical Practice
This book describes the development of systems of magnetic resonance imaging using the higher magnetic field strength of 3 tesla, in comparison to the current gold standard of 1.5 tesla. It is the first monography on high-field Brain MR in Neuroradiology
Herbs for stress & anxiety : How to make and use herbal remedies to strengthen the nervous system
Treat stress, anxiety, depression, and more with simple herbal remedies that calm your mind, build a healthy nervous system, and promote lasting peace. In this informative guide, renowned herbalist Rosemary Gladstar profiles 21 herbs proven to be effective at soothing common ailments like insomnia, panic attacks, skin conditions, and migraines. With simple directions for making herbal mixtures that can be used in delicious teas, tinctures, and capsules, Gladstar shows you how to harness the power of nature to achieve a more relaxed and fulfilling life.
Herbs for common ailments : How to make and use herbal remedies for home health care
Shows you how to use 56 common herbs to address a wide range of everyday ailments, from burns, wounds, and itchy skin to headaches, congestion, indigestion, strains, bruises, sore throats, coughs, fevers, colic, cramps, and insomnia. She also shows you how to stock a simple first-aid kit with safe, effective herbal remedies.
Herbals as nutraceuticals : Their role in healthcare
Herbal nutraceuticals demonstrate a variety of therapeutic benefits and have been found to prevent, treat, and even cure a range of diseases. This new book provides insight into nutraceuticals and their function in human health, highlighting their antimicrobial and immune-inflammatory properties. It describes the nutraceutical properties of various medicinal herbs and details the role of nutraceuticals in treating diseases such as Alzheimer's, Parkinson's, obesity, diabetes, cancer, cardiovascular diseases, skincare issues, and more.
Heat Shock Proteins and the Brain : Implications for Neurodegenerative Diseases and Neuroprotection
Neurodegenerative disorders such as Alzheimer’s disease, Huntington’s disease, Parkinson’s disease and amyotrophic lateral sclerosis have been termed ‘protein misfolding disorders’ that are char- terized by the neural accumulation of protein aggregates. Manipulation of the cellular stress response involving the induction of heat shock proteins offers a the- peutic strategy to counter conformational changes in neural proteins that trigger pathogenic cascades resulting in neurodegenerative diseases. Heat shock proteins are protein repair agents that provide a line of defense against misfolded, aggregati- prone proteins. Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection reviews current progress on neural heat shock proteins (HSP) in relation to neurodegenerative diseases (Part I), neuroprotection (Part II), ext- cellular HSP (Part III) and aging and control of life span (Part IV).
Gesundheitsversorgung am Lebensende : Soziale Ungleichheit in Bezug auf Institutionsaufenthalte und Sterbeorte = Health care at the end of life : Social inequality in relation to institutional stays and places of death
Damian Hedinger examines the question of health care at the end of life, which is becoming more and more important due to demographic aging and increasing life expectancy. He proceeds from both a scientific and a socio-political perspective and uses administrative data from Switzerland to find out why one spends a longer or shorter period in a home or hospital and why one dies where. It turns out that in addition to medical factors, socio-economic, familial and cultural determinants also have a significant influence on health care before death.
Genotype - Proteotype - Phenotype Relationships in Neurodegenerative Diseases
Improved understanding of role of protein dysmetabolism in neurodegeneration promises to improve diagnoses, facilitate the development of biological markers relevant to disease pathophysiology, and provide tractable therapeutic targets. This Fondation IPSEN conference summary provides an update on the latest advances of the role of protein misfolding in the pathophysiology of neurodegenerative diseases.
Genome editing in neurosciences
Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Médecine et Recherche has brought together experts from around the world that are applying genome editing to address important challenges in neuroscience, including basic biology in model organisms that has the power to reveal systems-level insight into how the nervous system develops and functions as well as research focused on understanding and treating human neurological disorders.
Fuzzy Modeling with Spatial Information for Geographic Problems
This book focuses on research advances in approaches for incorporating explicit handling of uncertainty, especially by fuzzy sets, to address geographic problems. It has two aims: to stimulate research in the theory and application of fuzzy sets to spatial information management and geographic problem solving; and to highlight advances that have matured so much that geoscientists, computer scientists, geographers, et al. use fuzzy modeling. The book includes examples of the use of fuzzy sets in representational issues such as terrain features, landscape morphology, spatial extents and approaches for spatial interpolation, plus applications using fuzzy sets covering data mining, spatial decision making, ecological simulation, and reliability in GIS.
Fundamentals of business-to-business marketing : Mastering business markets
Gives a comprehensive overview of the key principles of business marketing. The reader will be introduced into methods and theories in order to understand business markets and marketing better. Not only are the principles of business marketing addressed, But also deep knowledge of organizational buying and market research on business markets. The book sets the stage for developing marketing programs for business markets in their different facets.
Fuel Cells II
The concept to utilize an ion-conducting polymer membrane as a solid po- mer electrolyte offers several advantages regarding the design and operation of an electrochemical cell, as outlined in Volume 215, Chapter 1 (L. Gubler, G.G. Scherer). Essentially, the solvent and/or transport medium, e.g., H O, 2 + for the mobile ionic species, e.g., H for a cation exchange membrane, is taken up by and con?ned into the nano-dimensional morphology of the i- containingdomainsofthepolymer.Asaconsequence, aphaseseparationinto a hydrophilic ion-containing solvent phase and a hydrophobic polymer ba- bone phase establishes. Because of the narrow solid electrolyte gap in these cells, low ohmic losses reducing the overall cell voltage can be achieved, even at highcurrent densities.
Fuel Cells I
The concept to utilize an ion-conducting polymer membrane as a solid po- mer electrolyte offers several advantages regarding the design and operation of an electrochemical cell, as outlined in Volume 215, Chapter 1 (L. Gubler, G.G. Scherer). Essentially, the solvent and/or transport medium, e.g., H O, 2 + for the mobile ionic species, e.g., H for a cation exchange membrane, is taken up by and con?ned into the nano-dimensional morphology of the i- containingdomainsofthepolymer.Asaconsequence, aphaseseparationinto a hydrophilic ion-containing solvent phase and a hydrophobic polymer ba- bone phase establishes. Because of the narrow solid electrolyte gap in these cells, low ohmic losses reducing the overall cell voltage can be achieved, even at highcurrent densities.
Fragility fracture nursing : Holistic care and management of the orthogeriatric patient
Aims to provide a comprehensive but practical overview of the knowledge required for the assessment and management of the older adult with or at risk of fragility fracture. It considers this from the perspectives of all of the settings in which this group of patients receive nursing care.
Forensic Computing
In the second edition of this very successful book, Tony Sammes and Brian Jenkinson show how information held in computer systems can be recovered when it has been hidden or subverted by criminals, and give the reader the means to insure that it is accepted as admissible evidence in court.
Fields and Galois Theory
The pioneering work of Abel and Galois in the early nineteenth century demonstrated that the long-standing quest for a solution of quintic equations by radicals was fruitless: no formula can be found. The techniques they used were, in the end, more important than the resolution of a somewhat esoteric problem, for they were the genesis of modern abstract algebra. This book provides a gentle introduction to Galois theory suitable for third- and fourth-year undergraduates and beginning graduates. The approach is unashamedly unhistorical: it uses the language and techniques of abstract algebra to express complex arguments in contemporary terms. Thus the insolubility of the quintic by radicals is linked to the fact that the alternating group of degree 5 is simple - which is assuredly not the way Galois would have expressed the connection.
Fading Foundations : Probability and the Regress Problem
This book addresses the age-old problem of infinite regresses in epistemology. How can we ever come to know something if knowing requires having good reasons, and reasons can only be good if they are backed by good reasons in turn? The problem has puzzled philosophers ever since antiquity, giving rise to what is often called Agrippa's Trilemma. The current volume approaches the old problem in a provocative and thoroughly contemporary way. Taking seriously the idea that good reasons are typically probabilistic in character, it develops and defends a new solution that challenges venerable philosophical intuitions and explains why they were mistakenly held. Key to the new solution is the phenomenon of fading foundations, according to which distant reasons are less important than those that are nearby.
