الصفحة 2
الصفحة 2
Natural Compounds as Drugs ; Vol. II
This book highlights new trends and aspects in natural products research. It discusses the biodiversity-driven approaches which are now of eminent importance in natural products research, addressing the question why natural products display such a complex chemical information, what makes them often unique and what their characteristics are. Practical questions such as supply of natural substances and production optimization strategies are also covered.
Nanoparticles in Biomedical Imaging : Emerging Technologies and Applications
Fundamental Biomedical Technologies features titles in multidisciplinary, technology-driven areas, providing the foundations for breakthrough advances in medicine and biology. The term technology refers, in a vigorously unrestrictive sense, to a broad array of engineering disciplines, the sciences of computation and informatics, mathematical models exploiting and advancing methods of mathematical physics, and the development of novel, experimental discovery devices. Titles in this series are designed and selected to provide high-level visionary input for specialists, while presenting overviews of emerging fields for those in related areas. Volumes in this series aim to provide technologists with the material to gain competent entry into biomedical research and biomedical researchers to understand and embrace novel technological foundations and tools.
Nanoinformatics
Brings out the state of the art on how informatics-based tools are used and expected to be used in nanomaterials research. There has been great progress in the area in which “big-data” generated by experiments or computations are fully utilized to accelerate discovery of new materials, key factors, and design rules. Data-intensive approaches play indispensable roles in advanced materials characterization. "Materials informatics" is the central paradigm in the new trend. "Nanoinformatics" is its essential subset, which focuses on nanostructures of materials such as surfaces, interfaces, dopants, and point defects, playing a critical role in determining materials properties. There have been significant advances in experimental and computational techniques to characterize individual atoms in nanostructures and to gain quantitative information. The collaboration of researchers in materials science and information science is growing actively and is creating a new trend in materials science and engineering.
Mutagenic Impurities : Strategies for Identification and Control
In Mutagenic Impurities: Strategies for Identification and Control, distinguished chemist Andrew Teasdale delivers a thorough examination of mutagenic impurities and their impact on the pharmaceutical industry. The book incorporates the adoption of the ICH M7 guideline and focuses on mutagenic impurities from both a toxicological and analytical perspective.
Multi-Scale Approaches in Drug Discovery : From Empirical Knowledge to In silico Experiments and Back
Drug discovery is an expensive, time-consuming process and the modern drug discovery community is constantly challenged not only with discovering novel bioactive agents to combat resistance from known diseases and fight against new ones, but to do so in a way that is economically effective. Advances in both experimental and theoretical/computational methods envisage that the greatest challenges in drug discovery can be most successfully addressed by using a multi-scale approach, drawing on the specialties of a whole host of different disciplines. Multi-Scale Approaches to Drug Discovery furnishes chemists with the detail they need to identify drug leads with the highest potential before isolating and synthesizing them to produce effective drugs with greater swiftness than classical methods may allow. This significantly speeds up the search for more efficient therapeutic agents.
Multiple-Aspect Analysis of Semantic Trajectories ; First International Workshop, MASTER 2019, Held in Conjunction with ECML-PKDD 2019, Würzburg, Germany, September 16, 2019, Proceedings
This book constitutes the refereed post-conference proceedings of the First International Workshop on Multiple-Aspect Analysis of Semantic Trajectories, MASTER 2019, held in conjunction with the 19th European Conference on Machine Learning and Knowledge Discovery in Databases, ECML PKDD 2019, in Würzburg, Germany, in September 2019.
Multi-Objective Evolutionary Algorithms for Knowledge Discovery from Databases
The present volume provides a collection of seven articles containing new and high quality research results demonstrating the significance of Multi-objective Evolutionary Algorithms (MOEA) for data mining tasks in Knowledge Discovery from Databases (KDD). These articles are written by leading experts around the world. It is shown how the different MOEAs can be utilized, both in individual and integrated manner, in various ways to efficiently mine data from large databases.
Multimedia Data Mining and Knowledge Discovery
Multimedia Data Mining and Knowledge Discovery provides an overview of the current state-of-the-art in the field of multimedia data mining and knowledge discovery, and discusses the variety of hot topics in multimedia data mining research. Consisting of an introductory section and four topical parts, the book describes the objectives and current tendencies in multimedia data mining research and their applications.
Multiagent System Technologies ; Vol. 4196 ; 4th German Conference, MATES 2006, Erfurt, Germany, September 19-20, 2006, Proceedings
This book constitutes the refereed proceedings of the 4th German Conference on Multiagent Systems Technologies, MATES 2006, co-located with Net.ObjectDays (NoDe 2006). The 15 revised full papers presented were carefully reviewed and selected from 52 submissions. The papers are organized in topical sections on agent communication and interaction, applications and simulation, agent planning, agent-oriented software engineering, as well as trust and security.
Multiagent System Technologies ; Vol. 3550 : 3rd German Conference, MATES 2005, Koblenz, Germany, September 11-13, 2005, Proceedings
After two successful MATES conferences in Erfurt 2003 and 2004, the 3rd G- man conference on Multi-agent System Technologies (MATES 2005) took place in Koblenz, Germany, in September 2005, and was co-located with the 28th German Conference on Arti?cial Intelligence (KI 2005). Building onotheragent-related events in Germany in the past, and organized by the GI German Special Interest Group on Distributed Arti?cial Intelligence, the MATES conference series aims at promoting the theory and applications of agents and multiagent systems. In corporating the 9th International Workshopon Cooperative Information Agents (CIA 2005), the topics of interest for MATES 2005 also covered the ?elds of intelligent information agents and systems for the Internet and the (Semantic) Web. As in recent years, MATES 2005 provided a distinguished, lively and int- disciplinary forum for researchers, users, and developers of agent technology, to present and discuss the latest advances of research and development in the area of autonomous agents and multiagent systems. Accordingly, the topics of MATES 2005 covered the whole range from the theory to applications of age- and multiagent technology. The technical program included a total of 24 sci- ti?c talks, and demonstrations of selected running agent systems, and both the MATES 2005 Best Paper and the CIA 2005 System Innovation awards.
Multiagent System Technologies ; 5th German Conference, MATES 2007, Leipzig, Germany, September 24-26, 2007, Proceedings
The papers are organized in topical sections on engineering multi-agent systems, multi-agent planning and learning, multi-agent communication, interaction, and coordination, multi-agent resource allocation, multi-agent planning and simulation, as well as trust and reputation.
Molecular Mimicry : Infection Inducing Autoimmune Disease
The conceptual basis for molecular mimicry was first defined in the early 1980s when monoclonal antibodies against viruses were also shown to react with non-viral host protein; in this case, measles virus phosphoprotein cross-reacted with host cell cytokeratin, herpes simplex virus type 1 with host-cell vimentin and vaccinia virus with host-cell intermediate filaments. Following this discovery, others emerged, again at the clonal level, that T cell clones against proteins from a variety of infectious agents also reacted with host antigenic determinants. The clonal distinction was imperative fo.
Molecular evolutionary models in drug discovery
Explores the application of evolutionary molecular models in drug discovery in which secondary metabolites play a fundamental role. Secondary metabolites are not produced in isolation, they are the result of the interaction of genes, metabolism and the environment. The book examines the role of secondary metabolites as leads in drug discovery and on the development of a rational bioprospecting model for new medicines based on the evolution of secondary metabolism. These evolutionary models are part of biological systems and are the most reliable expression of the functioning of living beings.
Molecular docking for computer-aided drug design : Fundamentals, techniques, resources and applications
Molecular Docking for Computer-Aided Drug Design: Fundamentals, Techniques, Resources and Applications offers in-depth coverage on the use of molecular docking for drug design. The book is divided into three main sections that cover basic techniques, tools, web servers and applications. It is an essential reference for students and researchers involved in drug design and discovery.
Molecular biology : Structure and dynamics of genomes and proteomes
Illustrates the essential principles behind the transmission and expression of genetic information at the level of DNA, RNA, and proteins. Emphasis is on the experimental basis of discovery and the most recent advances in the field while presenting a rigorous, yet still concise, summary of the structural mechanisms of molecular biology. Topics new to this edition include the CRISPR-Cas gene editing system, Coronaviruses – structure, genome, vaccine and drug development, and newly recognized mechanisms for transcription termination.
Modern medicines from plants : Botanical histories of some of modern medicine’s most important drugs
Features information on plants from which we obtain modern prescription medicines. It outlines their historical uses as herbal medicines in the past two millennia, using primary sources, and describes how extracts from them, and their semisynthetic and synthetic derivatives, were developed to be today’s therapeutic drugs and diagnostic chemicals. This book describes medicinal plants and their habitats, the diseases that their medicines treat, and the science of how they work.
Modern medicine : biomedical devices, medical gases, radiopharmaceuticals, new drug discovery, Vol.2
Discusses the procedures of drug approval and regulatory requirements that must be met according to the United States Food and Drug Administration (FDA), the European Medical Agency (EMA), and the Central Drug Standard Control Organization (CDSCO). In the rapidly evolving landscape of modern medicine, groundbreaking innovations have emerged that are reshaping the way we approach healthcare. Modern Medicine delves into the cutting-edge realms of medical devices, medical gases, radiopharmaceuticals, and new drug discovery, offering a comprehensive exploration of these transformative fields that are revolutionizing patient care and medical practices.
Modelling, Computation and Optimization in Information Systems and Management Sciences ; 2nd International Conference MCO 2008, Metz, France - Luxembourg, September 8-10, 2008. Proceedings
This book constitutes the refereed proceedings of the Second International Conference MCO 2008, Metz, France, September 2008.The 65 revised full papers presented were carefully reviewed and selected from 160 submissions. The papers are organized in topical sections on optimization and decision making; data mining theory, systems and applications; computer vision and image processing; computer communications and networks; optimization and search techniques for security, reliability, trust.
Modeling Decisions for Artificial Intelligence ; Vol.3885 ; 3rd International Conference, MDAI 2006, Tarragona, Spain, April 3-5, 2006, Proceedings
This book constitutes the refereed proceedings of the Third International Conference on Modeling Decisions for Artificial Intelligence, MDAI 2006, held in Tarragona, Spain, in April 2006.
Modeling Decisions for Artificial Intelligence ; 5th International Conference, MDAI 2008 Sabadell, Spain, October 30-31, 2008. Proceedings
This book constitutes the refereed proceedings of the 5th International Conference on Modeling Decisions for Artificial Intelligence, MDAI 2008, held in Sabadell, Spain, in October 2008.The 19 revised full papers presented together with 2 invited lectures were thoroughly reviewed and selected from 43 submissions; they are devoted to theory and tools for modeling decisions, as well as applications that encompass decision making processes and information fusion techniques. The papers are organized in topical sections on aggregation operators, decision making, clustering and similarity, computational intelligence and optimization, as well as data privacy.
