الصفحة 2
الصفحة 2
Gentamicin : Biosynthesis, medicinal applications and potential side effects
Discusses the biosynthesis, medicinal applications and potential side effects of Gentamicin. Topics include Gentamicin used in combination therapy and applied to medicinal materials for clinical applications; use of natural products to enhance the antibiotic activity of Gentamicin and other aminoglycosides; regiospecific Gentamicin functionalization; Gentamicin and particle engineering; and the indications and adverse effects of Gentamicin.
General Principles of Tumor Immunotherapy : Basic and Clinical Applications of Tumor Immunology
Brings together the world’s leading authorities on tumor immunology. This book describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated through both experimental clinical trials and review of current standard of care therapeutic agents. This information will be invaluable to both students of immunology and cancer research and practicing physicians who have patients with cancer. The book provides a comprehensive overview of the field, demonstrates how advances in basic immunology can and are being applied to cancer, and describes the current status of approved immunotherapy regimens.
Gene delivery systems development and applications
Covers the development of gene therapy today, the technology involved, clinical applications of siRNA, non-viral vector-based mRNA delivery using nanotechnology, and RNA based vaccines for treating the infectious diseases. It also presents the current application of the CRISPR/Cas9 gene-editing technique which has revolutionized genome editing and which was awarded the 2020 Nobel Prize in Chemistry. Several new drug delivery systems are explored for the applications of gene therapy. These are found to be useful in treating chronic illnesses, including cancer and infectious diseases.
Fundamentals of x-ray imaging : Basic principles, quality control, clinical applications, and safety
Covers all X-ray modalities, including CT, mammography, fluoroscopy, dental radiography, and fusion imaging like PET-CT and SPECT-CT. It simplifies complex concepts for beginners while offering depth for advanced learners. Each chapter is engaging and addresses common questions from students and professionals.
Fundamentals of Clinical Data Science
This book comprehensively covers the fundamentals of clinical data science, focusing on data collection, modelling and clinical applications. Topics covered in the first section on data collection include: data sources, data at scale (big data), data stewardship (FAIR data) and related privacy concerns. Aspects of predictive modelling using techniques such as classification, regression or clustering, and prediction model validation will be covered in the second section. The third section covers aspects of (mobile) clinical decision support systems, operational excellence and value-based healthcare.
Functional MRI : Basic principles and clinical applications
This practical and timely volume presents an overview of the principles of fMRI and explains key concepts, including scanning methodologies, experimental research design, and data analysis. Informative discussions cover the technical and clinical challenges associated with fMRI. A neuroanatomical atlas adds to the sensible approach and serves as a useful reference by clearly illustrating normal functioning for important areas of the brain.
Fluconazole : Pharmacology, clinical uses and health effects
Fluconazole is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. In this book, the authors present current research in the study of the pharmacology, clinical uses and health effects of fluconazole. Topics discussed include the utilization of fluconazole in adult intensive care units; the use of fluconazole in veterinary species and a description of variances from the human experience as well as findings in veterinary species which may have applicability in human medicine; common clinical uses and in vitro activity features on fluconazole; and the discovery and development of medically-important antifungal agents, particularly the azole derivatives and the development of fluconazole and its clinical applications.
Energy Metabolism and Obesity : Research and Clinical Applications
Elucidate the most important aspects of genetic background, neuropeptide secretion and action, neuronal pathways, adipokines, gut hormones, and environmental influences (physical activity, pharmacologic agents, and surgical alteration of the gastrointestinal tract), as well as the complex interactions among them.
Endocrine-Disrupting Chemicals : From Basic Research to Clinical Practice
This book presents a translational approach to EDC research, spanning both basic biology and clinical applications, and provides a critical link between the laboratory and the physicians’ office. Scientists and physicians engaged in EDC studies or practice will find that this volume offers insight across all areas of EDC research, including clarifying the mechanisms for EDC effects, understanding the adverse affects of EDCs on humans and wildlife, and offering solutions to the problems created by exposures to EDCs.
Échographie de contraste : Méthodologie et applications cliniques = Contrast ultrasound : Methodology and clinical applications
The availability of ultrasound contrast agents has introduced a new dimension in ultrasound examination with the possibility of real-time exploration of the kinetics of contrast enhancement of various lesions. The potential indications for these microbubbles affect almost all deep and superficial organs, but also the possibilities of pharmacological studies for neoangiogenesis or therapeutic guidance by physical methods. Finally, new applications are emerging in the field of targeted products and the transport of active ingredients. It seemed opportune to us to attempt to take stock of this changing world through intense collaboration between the various teams involved and recognized in this field, of which unfortunately, only some are represented here. We want this book to be a current reference point for contrast ultrasound, a point that will certainly require development in the coming years. He strongly demonstrates that ultrasound can play a very important role in modern diagnostic and therapeutic imaging because of their diagnostic performance but also because of their non-invasive nature. We hope you enjoy looking for useful information as much as we did discovering real-time functional ultrasound imaging and writing these various chapters.
Drug Delivery Systems for Metabolic Disorders
Covers recent developments in advanced drug delivery systems in various metabolic disorders, including disturbances in protein, lipid, carbohydrate and hormone metabolism and lysosomal and mitochondrial disorders. It provides a brief introduction to metabolic disorders, along with a focus on the current landscape and trends in understanding disease pathology using different in vitro and in vivo models required for clinical applications and developments of new therapeutics.
Double Balloon Endoscopy : Theory and Practice
The chapters of this book describe the principles, insertion technique, and clinical applications of double-balloon endoscopy, which will become the gold standard of enteroscopy and may well eliminate the need for intraoperative enteroscopy in many patients.
Doppler Ultrasound in Obstetrics and Gynecology
Doppler Ultrasound in Obstetrics & Gynecology encompasses the full spectrum of clinical applications of Doppler ultrasound for the practicing obstetrician-gynecologist, including the latest advances in 3D and color Doppler and the newest techniques in 4D fetal echocardiography. Written by preeminent experts in the field, the book covers the basic and physical principles of Doppler ultrasound; the use of Doppler for fetal examination, including fetal cerebral circulation; Doppler echocardiography of the fetal heart; and the use of Doppler for postdated pregnancy and in cases of multiple gestation. Chapters on the use of Doppler for gynecologic investigation include ultrasound in ectopic pregnancy, for infertility, for benign disorders and for gynecologic malignancies.
Dipeptidyl Aminopeptidases : Basic Science and Clinical Applications
Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses, and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes. Leading experts in the field will contribute to this book, which will present a state-of-the-art view on these enzymes at a time when our understanding of their function is growing ever more rapidly and therapeutic options have become imminent. The sections of the book will focus on various topics including DP IV and related enzymes in: expression and function, metabolic disorders, immune mechanisms and immune disorders, neuronal diseases and cancer, and related drug development.
Digitization in Dentistry : Clinical Applications
Provides evidence-based guidance on the clinical applications of digital dentistry, that is, the use of dental technologies or devices that incorporate digital or computer-controlled components for the performance of dental procedures. Readers will find practically oriented information on the digital procedures currently in use in various fields of dental practice, including, for example, diagnosis and treatment planning, oral radiography, endodontics, orthodontics, implant dentistry, and esthetic dentistry. The aim is to equip practitioners with the knowledge required in order to enhance their daily practice. To this end, a problem-solving approach is adopted, with emphasis on key concepts and presentation of details in a sequential and easy to follow manner. Clear recommendations are set out, and helpful tips and tricks are highlighted.
Dental Sleep Medicine A Clinical Guide
Enables dentists to understand various aspects of dental sleep medicine, and to recognize the signs and symptoms of sleep disorders in their patients. It discusses potential negative impact of a sleep disorder on oral and systemic health, and shows how to collaborate with others in order to implement appropriate patient management. The first part of the book concentrated on the scientific background of sleep medicine in connection to dentistry covering the physiology of sleep, classifications of sleep disorders, their diagnosis as well as medical and dental comorbidities. The second part of the book is dedicated to clinical applications like CPAP therapy, oral appliance therapy, surgical procedures and adjunct therapies. Last, the future of dental sleep medicine is discussed.
Dental biomaterials: from fundamental principles to clinical applications
Novel approaches are being developed to prevent and treat prevalent oral diseases like dental caries, periodontitis, and oral cancer. Researchers are also exploring the potential of biomaterials in regenerative dentistry, such as promoting bone growth and repairing damaged oral tissues.The ongoing research and development in dental materials and biomaterials holds great promise for improving oral health outcomes. However, it is imperative to maintain a sustained focus on research to fully leverage their potential and effectively address the existing gaps in dental care.In the special issue titled "Dental Biomaterials: From Fundamental Principles to Clinical Applications," significant findings have emerged from a variety of sources, including in vitro experiments and clinical trials.
Deformable Models : Biomedical and Clinical Applications
Deformable Models: Biomedical and Clinical Applications is the first entry in the two-volume set which provides a wide cross-section of the methods and algorithms of variational and Partial-Differential Equations (PDE) methods in biomedical image analysis. The chapters of Deformable Models: Biomedical and Clinical Applications are written by the well-known researchers in this field, and the presentation style goes beyond an intricate abstraction of the theory into real application of the methods and description of the algorithms that were implemented. As such these chapters will serve the main goal of the editors of these two volumes in bringing down to earth the latest in variational and PDE methods in modeling of soft tissues.
Craniofacial 3D Imaging : Current Concepts in Orthodontics and Oral and Maxillofacial Surgery
This book is designed to serve as an up-to-date reference on the use of cone-beam computed tomography for the purpose of 3D imaging of the craniofacial complex. The focus is in particular on the ways in which craniofacial 3D imaging changes how we think about conventional diagnosis and treatment planning and on its clinical applications within orthodontics and oral and maxillofacial surgery.
Coordination : Neural, Behavioral and Social Dynamics
One of the most striking features of Coordination Dynamics is its interdisciplinary character. The problems we are trying to solve in this field range from behavioral phenomena of interlimb coordination and coordination between stimuli and movements (perception-action tasks) through neural activation patterns that can be observed during these tasks to clinical applications and social behavior. It is not surprising that close collaboration among scientists from different fields as psychology, kinesiology, neurology and even physics are imperative to deal with the enormous difficulties we are facing when we try to understand a system as complex as the human brain.
