New Perspectives on Aloe
The contents include a brief introduction of aloe, isolation, purification, and structural analysis of components, and various physiological effects of those components for possible use as health foods or drugs. Various functions identified were wound healing, angiogenesis, anti-allergy, skin whitening, stimulation of cell proliferation such as liver or kidney, protection against nephrotoxicity, and immune modulation. Moreover, we suggest standardization and quality control procedures for manufacturing raw aloe, and how to develop related products for successful application of aloe. This is important in Korea because last year the Korean government listed aloe as a health food for which the government establishes regulatory laws. Therefore, many scientists in Korea who are interested in studying health foods would be interested in this kind of text. Other major fields related to this kind of research will be medicine, biology, pharmaceutics, natural products and analytics.
New Partnerships for Innovation in Microfinance
"The book presents valuable information with a strong analytical tilt. … targets economists and managers in banking and development finance organizations, as well as policy makers, international development organizations, and development agencies. Because it covers a range of issues related to funding microfinance, and is written in relatively simple language, yet intelligently argued, it can be used as a resource book for courses on microfinance funding and development. … a useful read for practitioners in the sector."
New insights in machine learning and deep neural networks
Gatheres ten exemplary papers, each delineating advancements within the spheres of machine learning and deep neural networks. Commencing with a thorough exploration by Figueira and Vaz, readers are introduced to the nuances of synthetic data generation and evaluation, followed closely by Silva and Pedroso's systematic approach to leveraging deep reinforcement learning within the intricate realm of delivery logistics. Kamran et al. contribute an astute methodology for camouflage object segmentation, whereas Pinheiro and collaborators offer a crafted semi-supervised strategy for predicting EGFR mutations via CT images. Subsequent contributions, such as Lee and Yoo's framework for portrait emotion recognition and Balakrishnan et al.'s analytical exploration of transformer models for Twitter disaster detection, further exemplify the depth of research contained herein.
Network Performance Analysis : Using the J Programming Language
This useful volume introduces concepts and principles of network performance analysis by example, using the J programming language. J is rich in mathematical functionality, which makes it an ideal tool for analytical methods. The book favours a practical approach and develops functions in J to demonstrate mathematical concepts, thereby enabling readers to explore the underlying principles behind network performance analysis. In addition, this allows the subject to become more accessible to those who, although have a mathematical background, are not pure mathematicians.
Nearest Neighbor Search : A Database Perspective
Modern applications are both data and computationally intensive and require the storage and manipulation of voluminous traditional (alphanumeric) and nontraditional data sets (images, text, geometric objects, time-series). Examples of such emerging application domains are: Geographical Information Systems (GIS), Multimedia Information Systems, CAD/CAM, Time-Series Analysis, Medical Information Sstems, On-Line Analytical Processing (OLAP), and Data Mining. These applications pose diverse requirements with respect to the information and the operations that need to be supported. From the database perspective, new techniques and tools therefore need to be developed towards increased processing efficiency. This monograph explores the way spatial database management systems aim at supporting queries that involve the space characteristics of the underlying data, and discusses query processing techniques for nearest neighbor queries. It provides both basic concepts and state-of-the-art results in spatial databases and parallel processing research, and studies numerous applications of nearest neighbor queries.
Natural product experiments in drug discovery
Explores a wide range of evidence-based complementary medicine and various bio-analytical techniques used to define botanical products. Collecting recent work and current developments in the field of contemporary phytomedicine as well as their future possibilities in human health care, the book includes unique contributions in the form of chapters on phytomedicine and screening biological activities explained with diverse hyphenated techniques, as well as issues related to herbal medications, such as efficacy, adulteration, safety, toxicity, regulations, and drug delivery. Written for the Springer Protocols Handbooks series, chapters feature advice from experts on how to best conduct future experiments. Extensive and practical, Natural Product Experiments in Drug Discovery serves as an ideal reference for students, professors, and researchers in universities, R&D institutes, pharmaceutical and herbal enterprises, and health organizations.
Nanobiosensors : From design to applications
Nanobiosensors - From Design to Applications covers several aspects of biosensors beginning from the basic concepts to advanced level research. It will help to bridge the gap between various aspects of biosensors development technology and applications. It covers biosensors related material in broad spectrum such as basic concepts, biosensors & their classification, biomarkers & their role in biosensors, nanostructures-based biosensors, applications of biosensors in human diseases, drug detection, toxins, and smart phone based biosensors.
Mutagenic Impurities : Strategies for Identification and Control
In Mutagenic Impurities: Strategies for Identification and Control, distinguished chemist Andrew Teasdale delivers a thorough examination of mutagenic impurities and their impact on the pharmaceutical industry. The book incorporates the adoption of the ICH M7 guideline and focuses on mutagenic impurities from both a toxicological and analytical perspective.
Multiple-Aspect Analysis of Semantic Trajectories ; First International Workshop, MASTER 2019, Held in Conjunction with ECML-PKDD 2019, Würzburg, Germany, September 16, 2019, Proceedings
This book constitutes the refereed post-conference proceedings of the First International Workshop on Multiple-Aspect Analysis of Semantic Trajectories, MASTER 2019, held in conjunction with the 19th European Conference on Machine Learning and Knowledge Discovery in Databases, ECML PKDD 2019, in Würzburg, Germany, in September 2019.
Multiphase Flow Dynamics 2 : Thermal and Mechanical Interactions ; 3rd ed.
Multi-phase flows are part of our natural environment such as tornadoes, typhoons, air and water pollution and volcanic activities as well as part of industrial technology such as power plants, combustion engines, propulsion systems, or chemical and biological industry. The industrial use of multi-phase systems requires analytical and numerical strategies for predicting their behavior. In its third extended edition this book contains theory, methods and practical experience for describing complex transient multi-phase processes in arbitrary geometrical configurations. This book provides a systematic presentation of the theory and practice of numerical multi-phase fluid dynamics. In the present second volume the mechanical and thermal interactions in multiphase dynamics are provided. This third edition includes various updates, extensions, improvements and corrections.
Multiphase Flow Dynamics 1 : Fundamentals ; 3rd ed.
Multi-phase flows are part of our natural environment such as tornadoes, typhoons, air and water pollution and volcanic activities as well as part of industrial technology such as power plants, combustion engines, propulsion systems, or chemical and biological industry. The industrial use of multi-phase systems requires analytical and numerical strategies for predicting their behavior. In its third extended edition this monograph contains theory, methods and practical experience for describing complex transient multi-phase processes in arbitrary geometrical configurations, providing a systematic presentation of the theory and practice of numerical multi-phase fluid dynamics. This third edition includes various updates, extensions and improvements in all book chapters.
Multimedia big data computing for IoT applications : Concepts, paradigms and solutions
This book considers all aspects of managing the complexity of Multimedia Big Data Computing (MMBD) for IoT applications and develops a comprehensive taxonomy. It also discusses a process model that addresses a number of research challenges associated with MMBD, such as scalability, accessibility, reliability, heterogeneity, and Quality of Service (QoS) requirements, presenting case studies to demonstrate its application. Further, the book examines the layered architecture of MMBD computing and compares the life cycle of both big data and MMBD. Written by leading experts, it also includes numerous solved examples, technical descriptions, scenarios, procedures, and algorithms.
Multilevel Block Factorization Preconditioners : Matrix-based Analysis and Algorithms for Solving Finite Element Equations
This monograph is the first to provide a comprehensive, self-contained and rigorous presentation of some of the most powerful preconditioning methods for solving finite element equations in a common block-matrix factorization framework. Topics covered include the classical incomplete block-factorization preconditioners and the most efficient methods such as the multigrid, algebraic multigrid, and domain decomposition. Additionally, the author discusses preconditioning of saddle-point, nonsymmetric and indefinite problems, as well as preconditioning of certain nonlinear and quadratic constrained minimization problems that typically arise in contact mechanics. The book presents analytical as well as algorithmic aspects.
Monographs in contact allergy ; Vol.4 : Systemic drugs
Presents : Identification section; Occupational allergic contact dermatitis; and Cutaneous adverse drug reactions from systemic drugs caused by type IV (delayed-type) hypersensitivity, as shown by positive patch tests (e.g. maculopapular eruption, acute generalized exanthematous pustulosis [AGEP], symmetrical drug-related intertriginous and flexural exanthema [SDRIFE], fixed drug eruption, drug reaction with eosinophilia and systemic symptoms [DRESS], and photosensitivity). Separate chapters present an overview of the spectrum of allergic cutaneous drug reactions, diagnostic tests, immediate contact reactions (contact urticaria), and systemic drugs that have acquired delayed-type hypersensitivity only by cross-reactivity.
Monitors of Organic Chemicals in the Environment : Semipermeable Membrane Devices
Modern, industrialized societies depend on a wide range of chemical substances such as fuels, plastics, biocides, pharmaceuticals and detergents for maintaining the high quality lifestyle to which we aspire. The challenge is to ensure that while we enjoy the benetsof thes esubstances,theirinevitablereleaseintoourbiosphere does not result in unwanted human and ecosystem exposures, and the risk of - verse effects. One response to this challenge has been the extensive effort to detect and analyze or monitor a multitude of chemicals in a variety of environmental media, especially toxic organic compounds in air, water, soils and biota. An extensive literature on these traditional techniques has evolved over the years.
Molecular Techniques in the Microbial Ecology of Fermented Foods
Molecular Methods and Microbial Ecology of Fermented Foods presents the latest findings in microbial ecology as determined by the application of molecular methods, reports the most recent advances in the field, and offers details on primers and protocols most suitable for studying specific food ecosystems. It provides analytical details and suggestions useful in research, as well as evaluation of the criticism of using novel approaches in food fermentation microbiology. This book also discusses new insights drawn from the use of bio-molecular techniques in the microbial ecology of fermented foods.
Molecular Gels : Materials with Self-Assembled Fibrillar Networks
Molecular gels and fibrillar networks – a comprehensive guide to experiment and theory Molecular Gels: Materials with Self-Assembled Fibrillar Networks provides a comprehensive treatise on gelators, especially low molecular-mass gelators (LMOGs), and the properties of their gels. The structures and modes of formation of the self-assembled fibrillar networks (SAFINs) that immobilize the liquid components of the gels are discussed experimentally and theoretically. The spectroscopic, rheological, and structural features of the different classes of LMOGs are also presented. Many examples of the application of the principal analytical techniques for investigation of molecular gels (including SANS, SAXS, WAXS, UV-vis absorption, fluorescence and CD spectroscopies, scanning electron, transmission electron and optical microscopies, and molecular modeling) are presented didactically and in-depth, as are several of the theories of the stages of aggregation of individual LMOG molecules leading to SAFINs. Several actual and potential applications of molecular gels in disparate fields (from silicate replication of nanostructures to art conservation) are described. Special emphasis is placed on perspectives for future developments.
Molecular bio-sensors and the role of metal ions
Represents a milestone of contemporary progress and understanding of molecular bio-sensors for metal ions. It is bringing together the latest research in academia and industry, and it also emphasizes the spectrum of evolving regulations from regulatory bodies. This vibrant research area is covered by 31 internationally recognized experts. The impact of MILS-23 is manifested by more than 1300 references and close to 200 figures, more than 100 of them in color; further information is summarized in several tables. In conclusion, Volume 23 significantly advances our understanding of Molecular Bio-Sensors, it is therefore an essential resource for scientists working in the wide range from earth sciences, material sciences, physics, pharmacology, enzymology, analytical, organic, and inorganic biochemistry all the way through to medicine including the clinic.
Modern avenues in metal-nucleic acid chemistry
Provides a timely overview of selected relevant developments in a field which previously had a pronounced focus on fundamental chemistry aspects such as coordination principles, structural chemistry, and consequences for biological processes and disease-related medicinal issues. More recently, also as a consequence of the advent of supramolecular chemistry, advancements in nanochemistry, and new bio-analytical methods, novel aspects of this field have emerged. MILS-25 gives a state-of-the-art account on the present state of research in this field, addressing, among others, porous materials, non-covalent interactions, stimuli-responsive bioconjugates, DNA-templated metal arrays and nanoclusters, genotyping, guanine quadruplexes, and riboswitches.
Modelling and Estimation Strategies for Fault Diagnosis of Non-Linear Systems : From Analytical to Soft Computing Approaches
This monograph presents a variety of techniques that can be used for designing robust fault diagnosis schemes for non-linear systems. The introductory part of the book is of a tutorial value and can be perceived as a good starting point for the new-comers to this field. Subsequently, advanced robust observer structures are presented. Parameter estimation based techniques are discussed as well. A particular attention is drawn to experimental design for fault diagnosis. The book also presents a number of robust soft computing approaches utilizing evolutionary algorithms and neural networks. All approaches described in this book are illustrated by practical applications.



















