الصفحة 2
الصفحة 2
Handbook of plant and animal toxins in food : Occurrence, toxicity, and prevention
Focuses on various selected toxins in foods derived from plants as well as animals. The prominent plant toxins include solanine and chaconine, mushroom toxins, phytates, tannins, oxalates, goitrogens, gossypol, phytohemagglutinins, erucic acid, saponins, cyanogenic glycosides, enzyme inhibitors, BOAA (lathyrogens), toxic amino acids and toxic fatty acids. The prominent animal toxins covered in the book include various seafood toxins, shellfish toxins and biogenic amines. Presents complete information about a plethora of toxins Provides quick and easy access to data on major plant and animal toxins Covers distribution of toxins in the plant and animal kingdom Provides comprehensive information on chemistry, safety and precautions of each toxin
Handbook of Pharmaceutical Excipients
Recognised as the world’s most authoritative source of information on pharmaceutical excipients. It provides you with a one stop resource when researching an excipient for use. The 400+ monographs are also thoroughly cross referenced and indexed to allow their identification by chemical, non proprietary or trade names. Content include: - Over 420 fully referenced excipient monographs, many including IR, Raman, and NIR spectra / 13 new monographs including several amino acids and hydrated silicon dioxide / 250 existing monographs reviewed / New chapters include excipient selection for orally inhaled and injectable formulations
Handbook of Pathogens and Diseases in Cephalopods
The aim of this book is to facilitate the identification and description of the different organs as well as pathogens and diseases affecting the most representative species of cephalopods focussed on Sepia officinalis, Loligo vulgaris and Octopus vulgaris. These species are valuable ‘morphotype’ models and belong to the taxonomic groups Sepioidea, Myopsida and Octopoda, which include most of the species with a high market value and aquaculture potential. The study is based on photographs at macroscopic and histological level in order to illustrate the role of the most important pathogens and related diseases from the view of a pathological diagnosis. The reader is able to familiarize with functional anatomy, necropsy and general histology of adults and paralarvae, as well as with the identification of different pathogens and pathologies. This work is thus an invaluable guide for the diagnosis of cephalopod diseases. Besides including pathogens for non-European cephalopod species, it also provides a useful contribution encouraging marine pathologists, parasitologists, veterinarians and those involved in fishery sanitary assessments, aquarium maintenance and aquaculture practices aiming to increase their knowledge about the pathology of cephalopods.
Handbook of neurochemistry and molecular neurobiology : Amino acids and peptides in the nervous system
It is our belief that this volume of the Handbook of Neurochemistry and Molecular Neurobiology provides an excellent review of the tremendous advances of the past decades in the neurochemical and molecular biological aspects of cerebral ischemia. It is hoped that these advances will provide an impetus for basic scientists and clinicians to further their translational research and to promote the insights for development of therapeutic interventions for stroke.
Green Chemistry and Sustainable Technology : Biological, Pharmaceutical, and Macromolecular Systems
Taking an interdisciplinary approach, this new volume brings together innovative research, new concepts, and novel developments in the application of new tools in green chemistry and sustainable technology. The diverse coverage includes chapters on ionic liquids as green solvents, an environmentally friendly approach to the synthesis and biological evaluation of α-aminophosphonate derivatives, the application of nanotechnology in biological sciences and green chemistry, ecofriendly polymers, the effect of global warming and greenhouse gases on environmental system, and more.
Glucoszmine and Chondroitin between reality and tllusion
Despite the development of cancer treatments and the introduction of new treatments other than traditional treatments, the death rate is still high around the world for each type of cancer. Although conventional treatments are still common, as a first method in treatment, advanced new treatments have opened new horizon and have shown good efficacy in inhibiting cancer, either by treating them alone or in combination with conventional treatments, such as chemotherapy and radiation therapy. We mention in this research the latest methods of cancer treatment, such as targeted therapies in the treatment of solid cancers and leukemia. and will also mention the annual incidence rates of lines around the world. In cooperation with the head of the hematology division at the Mouwasat Hospital, Dr. Amin Suleiman, we studied cases of CML and MM patients being treated with modern therapies.
Ghrelin more than hunger hormone
Ghrelin is a stomach hormone that acts as an endogenous ligand of orphan G-protein-coupled receptor. Ghrelin is a 28-amino acid peptide existing in two major forms: n-octanoyl-modified ghrelin, which possesses an n-octanoyl modification on serine-3 and des-acyl ghrelin. Fatty acid modification of ghrelin is essential for ghrelin-induced growth hormone release from the pituitary and appetite stimulation. This acyl-modification of ghrelin is catalysed by ghrelin-O- acyl transferase recently identified.
Gentamicin : Biosynthesis, medicinal applications and potential side effects
Discusses the biosynthesis, medicinal applications and potential side effects of Gentamicin. Topics include Gentamicin used in combination therapy and applied to medicinal materials for clinical applications; use of natural products to enhance the antibiotic activity of Gentamicin and other aminoglycosides; regiospecific Gentamicin functionalization; Gentamicin and particle engineering; and the indications and adverse effects of Gentamicin.
Fundamentals of Protein Structure and Function
This book serves as an introduction to the fundamentals of protein structure and function. Starting with their make up from simple building blocks called amino acids, the 3-dimensional structure of proteins is explained. This is followed by an introduction into enzymology and modern concepts of enzyme kinetics, taking into account the physiological and medical significance of this often neglected topic.
Frontiers of high performance computing and networking – ISPA 2006 workshops ; ISPA 2006 International workshops FHPCN, XHPC, S-GRACE, GridGIS, HPC-GTP, PDCE, ParDMCom, WOMP, ISDF, and UPWN, Sorrento, Italy, December 4 -7, 2006, Proceedings
This book constitutes the refereed joint proceedings of ten internationl workshops held in conjunction with the 4th International Symposium on Parallel and Distributed Processing and Applications, ISPA 2006, held in Sorrento, Italy in December 2006 (see LNCS 4330). Topics addressed are frontiers of high performance computing and networking (FHPCN 2006), XEN in HPC cluster and grid computing environments (XHPC 2006), semantic grid applications in computing and engineering (S-GRACE 2006), fertilization of grid computing and geographic information system (GridGIS 2006), high performance computing in genomic proteomic and transcriptomic (HPC-GTP 2006), parallel and distributed computing in engineering (PDCE 2006), parallel and distributed multimedia computing (ParDMCom 2006), middleware performance (WOMP 2006), information security and digital forensics (ISDF 2006), and ubiquitous processing for wireless networks (UPWN 2006).
Encyclopedia of Genetics, Genomics, Proteomics and Informatics
It includes about 56% more words than the 1,392-page 2nd edition of 2003. The number of illustrations increased to almost 2,000 and their quality has improved by design and four colors. Cross-references among entries are expanded. The statements are supported by references; more than 14,000 journal papers and more than 3,000 books are listed. The book includes ~1,800 current databases and web servers. Retractions and corrigenda are pointed out.It covers the basics and the latest in genomics, proteomics, genetic engineering, small RNAs, transcription factories, chromosome territories, stem cells, genetic networks, epigenetics, prions, hereditary diseases, patents, etc. Similar integrated information is not available in textbooks or on the Internet. The journal reviews called it the best, high-quality resource for researchers, instructors and students of basic and applied biology, as well as for physicians and lawyers or even for interested laymen because of the clarity of presentation.
Emergent Computation : Emphasizing Bioinformatics
Emergent Computation is concerned with recent applications of Mathematical Linguistics or Automata Theory. This subject has a primary focus upon ""Bioinformatics"" (the Genome and arising interest in the Proteome), but the closing chapter also examines applications in Biology, Medicine, Anthropology, etc. The book is composed of an organized examination of DNA, RNA, and the assembly of amino acids into proteins. Rather than examine these areas from a purely mathematical viewpoint (that excludes much of the biochemical reality), the author uses scientific papers written mostly by biochemists based upon their laboratory observations. Thus while DNA may exist in its double stranded form, triple stranded forms are not excluded. Similarly, while bases exist in Watson-Crick complements, mismatched bases and abasic pairs are not excluded, nor are Hoogsteen bonds. Just as there are four bases naturally found in DNA, the existence of additional bases is not ignored, nor amino acids in addition to the usual complement of 20. Can there be more than ""64"" possible codons? RNA is examined from the point of view of Nussinov plots.
Early Life Origins of Health and Disease
Early Life Origins of Health and Disease is a new book which presents and discusses the many factors that may have impact on normal development. In a concise and readable manner, the authors consider both the proven and suggestive evidence that the high prevalence of hypertension, diabetes, obesity and, in some populations, kidney disease, may not be all due to genetics or adult environment alone. There is good evidence that stress and more subtle dietary deficiencies, as well as placental malfunction, may increase the risk that the offspring will develop these problems in later life. Finally, new and emerging evidence for other areas of human health and disease such a motor control and mental health is critically reviewed for the first time. The book is a ‘must’ for all scientists interested in researching these areas, as there is a critical evaluation of the methodology used and suggestions for the ‘optimal’ way in which to investigate these phenomena.
Discovering Biomolecular Mechanisms with Computational Biology
In this anthology, leading researchers present critical reviews of methods and high-impact applications in computational biology that lead to results that also non-bioinformaticians must know to design efficient experimental research plans. Discovering Biomolecular Mechanisms with Computational Biology also summarizes non-trivial theoretical predictions for regulatory and metabolic networks that have received experimental confirmation. Discovering Biomolecular Mechanisms with Computational Biology is essential reading for life science researchers and higher-level students that work on biomolecular mechanisms and wish to understand the impact of computational biology for their success.
Dipeptidyl Aminopeptidases : Basic Science and Clinical Applications
Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses, and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes. Leading experts in the field will contribute to this book, which will present a state-of-the-art view on these enzymes at a time when our understanding of their function is growing ever more rapidly and therapeutic options have become imminent. The sections of the book will focus on various topics including DP IV and related enzymes in: expression and function, metabolic disorders, immune mechanisms and immune disorders, neuronal diseases and cancer, and related drug development.
Data Mining in Bioinformatics
8. 1. 1 Protein Subcellular Location The life sciences have entered the post-genome era where the focus of biological research has shifted from genome sequences to protein functionality. Withwhole-genomedraftsofmouseandhumaninhand,scientistsareputting more and more e?ort into obtaining information about the entire proteome in a given cell type. The properties of a protein include its amino acid sequences, its expression levels under various developmental stages and in di?erent tissues, its3Dstructure and activesites,its functionalandstructural binding partners, and its subcellular location. Protein subcellular location is important for understanding protein function inside the cell. For example, the observation that the product of a gene is localized in mitochondria will support the hypothesis that this protein or gene is involved in energy metabolism. Proteins localized in the cytoskeleton are probably involved in intracellular tra?cking and support.
CRP and the relation with heart disease
Cardiovascular diseases are the leading causes of mortality and morbidity in industrialized and developing countries. Many efforts have been undertaken during the last decades to identify environmental, behavioral and genetic factors modulating the risk of cardiovascular diseases.It will explain the role of CRP - an acute-phase protein- as indicator of potential cardiovascular disease as well as a predictor of the risk for heart disease and future heart attack
Computational Science and Its Applications - ICCSA 2008 ; International Conference, Perugia, Italy, June 30– July 3, 2008, Proceedings, Part II
The two-volume set LNCS 5072 and 5073 constitutes the refereed proceedings of the International Conference on Computational Science and Its Applications, ICCSA 2008, held in Perugia, Italy in June/July 2008.
Computational science and its applications - ICCSA 2008 ; International Conference, Perugia, Italy, June 30 – July 3, 2008, Proceedings, Part I
The two-volume set LNCS 5072 and 5073 constitutes the refereed proceedings of the International Conference on Computational Science and Its Applications, ICCSA 2008, held in Perugia, Italy, in June/July, 2008.
Laboratory Guide to the Methods in Biochemical Genetics
This manual deals specifically with laboratory approaches to diagnosing inborn errors of metabolism. The key feature is that each chapter is sufficiently detailed so that any individual can adopt the described method into their own respective laboratory.
