الصفحة 2
الصفحة 2
Nonlinear Dynamics and Heterogeneous Interacting Agents
Economic application of nonlinear dynamics, microscopic agent-based modelling, and the use of artificial intelligence techniques as learning devices of boundedly rational actors are among the most exciting interdisciplinary ventures of economic theory over the past decade. This volume provides us with a most fascinating series of examples on "complexity in action" exemplifying the scope and explanatory power of these innovative approaches.
Non-Fungible Tokens (NFTs) : Examining the impact on consumers and marketing strategies
Focuses on the relevance of non-fungible token-based products in the current hyper-digitalized and hyper-connected world. Connecting the new NFTs’ technologies with academic literature on marketing, the authors highlight future research streams as well as strategies and factors that marketers and managers can use to promote this new type of product.
Noncommutative Geometry and Number Theory : Where Arithmetic meets Geometry and Physics
This volume collects and presents up-to-date research topics in arithmetic and noncommutative geometry and ideas from physics that point to possible new connections between the fields of number theory, algebraic geometry and noncommutative geometry. The articles collected in this volume present new noncommutative geometry perspectives on classical topics of number theory and arithmetic such as modular forms, class field theory, the theory of reductive p-adic groups, Shimura varieties, the local Lfactors of arithmetic varieties. They also show how arithmetic appears naturally in noncommutative geometry and in physics, in the residues of Feynman graphs, in the properties of noncommutative tori, and in the quantum Hall effect.
Noncommunicable diseases
Focuses on cardiovascular disease, diabetes, cancer and chronic respiratory disease and their five shared main risk factors (tobacco use, harmful use of alcohol, unhealthy diet, physical inactivity and air pollution) as defined by the United Nations, this book provides a synopsis of one of the world’s biggest challenges of the 21st century. NCDs prematurely claim the lives of millions of people across the world every year, with untold suffering to hundreds of millions more, trapping many people in poverty and curtailing economic growth and sustainable development. While resources between and within countries largely differ, the key principles of surveillance, prevention and management apply to all countries, as does the need to focus resources on the most cost-effective and affordable interventions and the need for strong political will, sufficient resources, and sustained and broad partnerships. This compendium consists of 59 short and accessible chapters in six sections: (i) describing and measuring the burden and impact of NCDs / (ii) the burden, epidemiology and priority interventions for individual NCDs / (iii) social determinants and risk factors for NCDs and priority interventions / (iv) global policy / (v) cross-cutting issues / and (vi) stakeholder action.
Nitrogen Fixation in Agriculture, Forestry, Ecology, and the Environment
Sustainability has a major part to play in the global challenge of continued development of regions, countries, and continents all around the World and biological nitrogen fixation has a key role in this process. This volume begins with chapters specifically addressing crops of major global importance, such as soybeans, rice, and sugar cane. It continues with a second important focus, agroforestry, and describes the use and promise of both legume trees with their rhizobial symbionts and other nitrogen-fixing trees with their actinorhizal colonization. An over-arching theme of all chapters is the interaction of the plants and trees with microbes and this theme allows other aspects of soil microbiology, such as interactions with arbuscular mycorrhizal fungi and the impact of soil-stress factors on biological nitrogen fixation, to be addressed. Furthermore, a link to basic science occurs through the inclusion of chapters describing the biogeochemically important nitrogen cycle and its key relationships among nitrogen fixation, nitrification, and denitrification. The volume then provides an up-to-date view of the production of microbial inocula, especially those for legume crops.
Nicotinic Acetylcholine Receptor Signaling in Neuroprotection
Presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. Accumulating evidence suggests that nAChRs in the CNS play important roles not only in excitatory neurotransmission but also in neuronal survival and related functions. Neuroprotection mediated by nAChRs in neurodegenerative diseases such as Alzheimer's disease is the major topic of this book. In response to rapidly evolving areas in clinical and laboratory neuropharmacology and neurochemistry, this volume provides in-depth coverage of neuroprotection in basic research and future developments in the clinical application of effective neuroprotective strategies in neurodegenerative diseases. This work appeals to both basic and clinical researchers in several fields, such as neuroscience, neurology, and pharmacology.
NF-kB/Rel Transcription Factor Family
Since its first discovery in the early 90’s, the NF-kB/Rel transcription factor family has drawn the attention of experimental biologists, medical profession, and biotech/pharmaceutical industries for its broad and diverse roles in all aspects of human biology and disease. NF-kB/Rel Transcription Factor Family intends to provide an up-to-date guide to the ever-expanding knowledge in the field of NF-kB/Rel transcription factor family.
New Vision of Multiblesclerosis
"There is an evidence that both the multiple sclerosis increased prevalence and incidence rate of over the last few decades. Therefore, the goal of our study is to highlight the causes and the risk factors of such neurological disease in order to raise the public awareness for its early symptoms to be able to treat the patients as early as possible and to have the best outcome. The symptoms of this disease are similar to some extent to other diseases so we will design a table and a test for differential diagnosis with such diseases because there is not a specific diagnostic test also taking into consideration to include in our current project A new promising medication (Radicava)which was first approved by FDA in 2015 in Japan 20 years after all old mentioned medications in this study and we started communication with a brilliant neurological doctor to plan using it first time ever in our country. Beside that we will recommend some important diet to follow for patients and some advises to avoid some risk factors which can develop this disease."
New Vision of Metformin in treating cancer
The anti-diabetic drug metformin is rapidly emerging as a potential anticancer agent. Metformin is a biguanide that is effective in treating type 2 diabetes and the insulin resistance syndromes, improves insulin resistance by reducing hepatic gluconeogensis and by enhancing glucose uptake by skeletal muscle. Metformin can reduce the incidence of cancers and can reduce the mortality from cancers, increase the response to treatment cancer cells when using radiotherapy and chemotherapy, reduce the likelihood of relapse. Diabetes can be a factor in the occurrence of various types of cancer, and develop a variety of cancers such as colo-rectal, pancreas and liver cancers, compared to non-diabetic patients. Incidence of various cancers is high among patients of T2DM due to insulin resistance and mitogenic effects caused by hyperglycemia.
New product development : An empirical approach to study of the effects of innovation strategy, organization learning and market Conditions
New product development (NPD) is considered as a process of learning. Successful NPD projects typically rely on knowledge and experience of multi-function teams. In addition to corporate strategy and organization learning, the external factors such as, market and competitive conditions also play a big role in driving business strategies.
New Perspectives in Political Ethnography
Ethnography is uniquely equipped to look microscopically at the foundations of political institutions and their attendant set of practices, just as it is ideally suited to explain why political actors behave the way they do and to identify the causes, processes and outcomes that are part and parcel of political life. The volume, based on a special issue of Qualitative Sociology has a two-fold purpose: to bring politics into the ethnographic literature and of ethnography in studies of politics. The case studies included are based on the research of ethnographers studying the various level of politics in Brazil, Japan, El Salvador, Bosnia, the Philippines, India and the United States. It will be of interest to those in the sociology of politics, political science and those looking for ethnographic research on a global level.
New Mechanisms for Tissue-Selective Estrogen-Free Contraception
Combined oral contraceptives are the most convenient and accepted method of hormonal contraception. Nevertheless, the medical community and consumers constantly demand innovation, additional benefits during use and lower hormonal load despite the high safety profile of available products. At the Ernst Schering Research Foundation Workshop 52, new perspectives and mechanisms for tissue-selective, estrogen-free contraception were discussed. The aim of the workshop was to bring together experts in the field of molecular and pharmacodynamic action of progestins with clinicians and medical experts to discuss potential medical endpoints, physiological reactions and (bio)marker useful describing the tissue selectivity and the contraceptive action of new progestins in different target organs. A major factor for successful realization of these new concepts is a deeper understanding of local pharmacological responses to progestins in general and to new progestins in particular.
New Insights in Medical Mycology
The aim of this book is to give an in-depth assessment of our current understanding of the Biology of the main fungal pathogens and how they interact with the host’s immune response. Each Chapter focuses on a specific fungal pathogen or group of pathogens and examines their biology and the factors that allow the fungus colonise and disseminate within the host. In addition each Chapter gives an indication of the challenges that remain to be tackled over the next 5 – 10 years in increasing our understanding of fungal pathogenicity.
New Frontiers in Lifestyle-Related Diseases
Akiyoshi Hosoyamada, M.D., Ph.D. President, Showa University Tokyo, Japan September 2007 v Preface The leading cause of death in Western countries and some developing countries is atherosclerotic cardiovascular diseases. Among them, acute myocardial infarction is the most common type of fatal disease, caused by the progression of atherosclerosis characterized by accumulation of choles terol in vascular walls. Development of atherosclerosis is greatly enhanced by major risk factors for cardiovascular diseases such as obesity, hyperlip idemia, diabetes (hyperglycemia), and hypertension. Among those, obesity frequently initiates a metabolic change that subsequently induces hyperlip idemia, diabetes, hypertension, and eventually atherosclerotic cardiovascu lar diseases. Because obesity and its related disorders largely depend on lifestyle factors such as high calorie intake and low physical activity, a series of disorders are termed lifestyle-related diseases.
New and Old Routes of Portuguese Emigration : Uncertain Futures at the Periphery of Europe
This book offers a comparative overview on Portuguese emigration in Europe and outside the EU in times of recession. In addition to the dynamics of movement, the book provides an in-depth analysis of the heterogeneity of this emigration. It deepens the multifaceted identities concerning social and professional pathways among highly skilled and less skilled emigrants. The labour market continues to be the main regulatory force of Portuguese emigration, which helps to explain the outflow and the processes of settlement and return. Nonetheless, this book demonstrates that non-economic factors have likewise been of great importance in the decision to emigrate.
Neutrophil : Methods and Protocols
Neutrophils, the most abundant white cells in humans, serve as the primary cellular defense against infection. This volume provides a concise set of protocols for assessing basic neutrophil functions and investigating specialized areas in neutrophil biology. Each of the protocols is written by leading researchers in the field and includes hints for success, as well as guidance for troubleshooting. Part I contains overviews of neutrophil biology, function, and disorders. Part II describes commonly used methods to isolate neutrophils from humans and other animal species. Part III details methods for investigating chemotaxis, transmigration, phagocytosis, and bactericidal activity. Part IV includes protocols that measure neutrophil apoptosis, calcium signal transduction, degranulation and detection of cytoplasmic granules, gene expression, transcription factors, and apoptosis. Part V provides multiple assays for measuring production of intracellular and/or extracellular reactive oxygen species, and a method that details use of the cell-free NADPH oxidase assay, an iconic assay for studies of the neutrophil NADPH oxidase. Part VI provides chapters that describe how to analyze formation and function of neutrophil extracellular traps.
Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity
This comprehensive volume, written by experts in the integrative fields of neuroscience, endocrinology and immunology, provides insight into the mechanisms by which neural and neuroendocrine factors influence susceptibility to infection and autoimmunity. The book focuses on multiple sclerosis as the prototypic autoimmune disease and discusses infectious diseases including anthrax, influenza virus, herpes virus and human immunodeficiency virus. The effects of stress on experimental models of multiple sclerosis and also clinical observations of stress in multiple sclerosis patients are discussed. Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity is an ideal book for researches and professionals in the fields of immunology, neuroscience, infectious disease, psychology, microbiology, virology, public health and pharmaceutical sciences.
Networked Neighbourhoods : The Connected Community in Context
The setting for this book is the networked community. The treatment of the subject matter is broad and interdisciplinary, with contributions from computer science, sociology, design, human factors and communication technology. The chapter contributors, drawn from across Europe and North America, offer a varied prospectus of commentary, critique, sociological enquiry, technological development and research findings, which provides a rounded account of the progressive intermingling of social and electronic networks.
Nature by Design : The Practice of Biophilic Design
Describes the basic principles, practices, and options for successfully implementing biophilic design. He shows us what is—and isn’t—good biophilic design using examples of workplaces, healthcare facilities, schools, commercial centers, religious structures, and hospitality settings. This book will to appeal to architects, designers, engineers, scholars of human evolutionary biology, and—with more than one hundred striking images of designs—anyone interested in nature‑inspired spaces.
Natural products and human diseases : Pharmacology, molecular targets, and therapeutic benefits
Provides insight into the clinical and translational application of natural products in human diseases Details the impact of natural products on a molecular basis Describes the identification of biomarkers, therapeutic effects of phytochemicals, and and new targets
