Dermatopathology
The book describes the principles of histopathologic patterns in selected acquired skin diseases, together with short clinical descriptions and case reports. The underlying, or possible underlying, mechanisms are elucidated, and controversial concepts are discussed. To facilitate the understanding of underlying mechanisms, the first chapters of the book comprise summaries of basic histology of lymphatics and blood vessels, relevant parts of general pathology, immunology, and molecular cell biology.
Deployment and operation of complex software in heterogeneous execution environments : The SODALITE approach
This book provides an overview of the work developed within the SODALITE project, which aims at facilitating the deployment and operation of distributed software on top of heterogeneous infrastructures, including cloud, HPC and edge resources. The experts participating in the project describe how SODALITE works and how it can be exploited by end users. While multiple languages and tools are available in the literature to support DevOps teams in the automation of deployment and operation steps, still these activities require specific know-how and skills that cannot be found in average teams. The SODALITE framework tackles this problem by offering modelling and smart editing features to allow those we call Application Ops Experts to work without knowing low level details about the adopted, potentially heterogeneous, infrastructures. The framework offers also mechanisms to verify the quality of the defined models, generate the corresponding executable infrastructural code, automatically wrap application components within proper execution containers, orchestrate all activities concerned with deployment and operation of all system components, and support on-the-fly self-adaptation and refactoring.
Dental neuroimaging: the role of the brain in oral functions
Provides an up-to-date overview of neuroimaging research on the neural mechanisms underlying mastication, swallowing, sensory processing, and other oral topics.
Dental Hard Tissues and Bonding : Interfacial Phenomena and Related Properties
This book comprehensively reviews bonding to enamel, dentin and cementum and analyses relevant adhesion mechanisms. Emphasis is placed on the characterization of material interfaces with dental tissues in situ. The volume also stresses the importance of appropriate experimental protocol design in facilitating clinically-relevant research methods, clarifies the mechanisms of adhesion of polymeric materials to hard dental tissues and furnishes a handy reference for routine clinical procedures in restorative and prosthetic dentistry as well as orthodontics. The book introduces important aspects of the chemistry of dental materials and their adaptation to dental hard tissues. It also analyses interfacial phenomena occurring during application of materials, including mechanical properties, and structural-compositional alterations. The text presents the current instrumental approaches in studying related issues and a summary of the current status of theories concerning bonding to dental tissues.
Dental caries
Provides information on the etiology, prevention, and treatment of tooth decay. Chapters cover such topics as dental biofilms, dietary factors, the association of Candida with early colonization of cariogenic microorganisms, oral diseases, the use of fluoride, and dental caries in disabled children.
Defending Life : The Nature of Host-Parasite Relations
Defending Life discusses the relationship between hosts and parasites. A major contention of the book is that the immune system depends ontologically on the ecosystem in which it is embedded; it would not have the features it has if it was not related in one way or other to parasitic agents and to the host’s own cells and tissues. To sustain the argument, life is investigated at all layers – from molecules up through cells, organisms and ecosystems. Together with the inverse course, which goes from ecological contingencies down to gene-expression profiles, the approach facilitates an advanced understanding of immunocompetence as well as its converse, immunoincompetence. The emphasis on analytical abstractions, coherent patterns and generative mechanisms makes possible the distinction between genuine causality and coincidental associations, and thus increases the understanding of why we observe what we observe. The book contains detailed descriptions of the immune system and the microbial world as well as methodological and conceptual clarifications.
Deep Learning, Machine Learning and IoT in Biomedical and Health Informatics : Techniques and Applications
Examines and demonstrates state-of-the-art approaches for IoT and Machine Learning based biomedical and health related applications. This book aims to provide computational methods for accumulating, updating and changing knowledge in intelligent systems and particularly learning mechanisms that help us to induce knowledge from the data. It is helpful in cases where direct algorithmic solutions are unavailable, there is lack of formal models, or the knowledge about the application domain is inadequately defined. In the future IoT has the impending capability to change the way we work and live. These computing methods also play a significant role in design and optimization in diverse engineering disciplines. With the influence and the development of the IoT concept, the need for AI (artificial intelligence) techniques has become more significant than ever.
Deciphering Growth
Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. In mammals, the major factors involved in the regulation of body growth are known. The combined knowledge concerning the endocrine and paracrine aspects of growth have led to the introduction of treatment regimens, most effective in GH-deficient children.
Datatype-Generic Programming ; International Spring School, SSDGP 2006, Nottingham, UK, April 24-27, 2006, Revised Lectures
A leitmotif in the evolution of programming paradigms has been the level and extent of parametrisation that is facilitated — the so-called genericity of the paradigm. The sorts of parameters that can be envisaged in a programming language range from simple values, like integers and fioating-point numbers, through structured values, types and classes, to kinds (the type of types and/or classes).Datatype-generic programming is about parametrising programsby the structure of the data that they manipulate. To appreciate the importance of data type genericity,one need look no further than the internet. The internet is a massive repository of structured data, but the structure is rarely exploited. For example, compression of data can be much more efiective if its structure is known, but most compression algorithms regard the input data as simply a string of bits, and take no account of its internal organisation. Datatype-generic programming is about exploiting the structure of data when it is relevant and ignoring it when it is not. Programming languages most c- monly used at the present time do not provide efiective mechanisms for do- menting and implementing datatype genericity.
Cytokines and Cancer
This volume provides a comprehensive review of the current knowledge on cytokines and cancer. Cytokines play a variety of roles in cancer, both as components of pathogenetic mechanisms, as well as agents used in the treatment of certain malignancies.The volume is divided in two sections. Section one focuses on current developments in the basic science field with particular emphasis on novel mechanisms of cytokine actions in malignant cells. The second section deals with translational and clinical research in the field, and many of the chapter authors were among the first to introduce several cytokines in the treatment of certain tumors.
Cyclin Dependent Kinase 5 (Cdk5)
Cyclin Dependent Kinase 5 provides a comprehensive and up-to-date collection of reviews on the discovery, signaling mechanisms and functions of Cdk5, as well as the potential implication of Cdk5 in the treatment of neurodegenerative diseases. Since the identification of this unique member of the Cdk family, Cdk5 has emerged as one of the most important signal transduction mediators in the development, maintenance and fine-tuning of neuronal functions and networking. Further studies have revealed that Cdk5 is also associated with the regulation of neuronal survival during development as well as in neurodegenerative diseases. These observations indicate that precise control of Cdk5 is essential for the regulation of neuronal survival. The pivotal role that Cdk5 appears to play in both the regulation of neuronal survival and synaptic functions thus raises the interesting possibility that Cdk5 inhibitors may have therapeutic potential for the treatment of a number of neurodegenerative diseases.
Current Topics in Innate Immunity
This volume represents a collection of topics on natural killer cells, mast cells, phagocytes, toll like receptors, complement, host defense in plants and invertebrates, evasion strategies of microorganisms, pathophysiology, protein structures, design of therapeutics, and experimental approaches discussed during the conference.
Current Perspectives in microRNAs (miRNA)
In this book, many new perspectives of the miRNA research are reviewed and discussed, including their roles in stem cell maintenance, embryonic development, tissue differentiation, adult physiology, disease pathology, cancer research, viral infection, genetic engineering in plants, and utility in cosmetic applications. These new findings may not only provide significant insight into the various mechanisms of miRNAs but also offer a great opportunity in developing new therapeutic interventions.
Current Developments in Bioerosion
The book opens with papers on the evolutionary significance of bioerosion, and subsequently ventures out to explore the remarkable diversity of bioerosive biota. From microboring bacteria to grazing echinoids, the studies use a variety of techniques ranging from field observations to sophisticated micro-computed tomography to investigate the ecological and environmental role of these organisms, including symbiotic interactions and alteration of non-carbonate substrates.
Ctenophores : Methods and protocols
Explores emerging approaches and methods inspired by recent research using ctenophores or placozoans, facilitating the study of these enigmatic species and ancient animal lineages. Practical protocols are integrated with introductory chapters about general biology, summarizing the diversity, evolution, genomics, development, and neurobiology of these organisms. Special chapters outline strategies and applications for culturing, microscopy, physiology, electrical synapses, and bioluminescence, molecular and single-cell biology, transcription factors, as well as gene and protein expression analyses. The book also contains bioinformatics and computational chapters covering peptidomics and epigenomics. Written for the highly successful Methods in Molecular Biology series, chapters include detailed implementation advice that leads to dependable results in the laboratory.
CSR and Codes of Business Ethics in the USA, Austria (EU) and China and their Enforcement in International Supply Chain Arbitrations
Analyzes the implementation of CSR reporting and codes of business conduct and ethics in the legal systems of the USA, Austria and China and their enforcement in international supply chain arbitrations. demonstrates that long-term profit maximization is increasingly intertwined with corporate ethics and CSR policies. In order to prevent window-dressing and greenwashing, certain control mechanisms and legal standards are required along the entire supply chain.
Cryptography and cryptanalysis in Java : Creating and programming advanced algorithms with Java SE 17 LTS and Jakarta EE 10
Includes challenging cryptographic solutions that are implemented in Java 17 and Jakarta EE 10. It provides a robust introduction to Java 17's new features and updates, a roadmap for Jakarta EE 10 security mechanisms, a unique presentation of the "hot points" (advantages and disadvantages) from the Java Cryptography Architecture (JCA), and more. You Will Learn : Develop programming skills for writing cryptography algorithms in Java / Dive into security schemes and modules using Java / Explore “good” vs “bad” cryptography based on processing execution times and reliability / Play with pseudo-random generators, hash functions, etc. / Leverage lattice-based cryptography methods, the NTRU framework library, and more
Cryptographic Algorithms on Reconfigurable Hardware
This book covers the study of computational methods, computer arithmetic algorithms, and design improvement techniques needed to implement efficient cryptographic algorithms in FPGA reconfigurable hardware platforms. The concepts and techniques reviewed in this book will make special emphasis on the practical aspects of reconfigurable hardware design, explaining the basic mathematics related and giving a comprehensive description of state-of-the-art implementation techniques. The authors show how high-speed cryptographic algorithms implementations can be achieved on reconfigurable hardware devices without posing prohibited high requirements for hardware resources. The material in this book will be of interest to engineering professionals, programmers, hardware designers, and graduate students interested in the development of security and cryptographic mechanisms at a beginning/intermediate level.
Critical issues in head and neck oncology : Key concepts from the eighth THNO meeting
Reviews the state-of-the-art knowledge with emphasis on multidisciplinary decision and management of head and neck cancer. The book provides significant detail on a wide range of topics including: the role of new targets for treatment, immunotherapy, resistance mechanisms, standardizing molecular profiling programs, and new methods to guide therapeutic approaches.
Creating Mobile Games : Using Java™ ME Platform to Put the Fun into Your Mobile Device and Cell Phone
Creating Mobile Games: shows you how to create a basic game and make it a professional one (by adding a pro look-and-feel by writing your own menus or using the open source J2ME Polish, and enabling marketing/billing from your own web site). Demonstrates Wireless Messaging and other optional APIs (using SMS, PIM, File Connection, Bluetooth, and so forth in a multiplayer game).



















