الصفحة 189
الصفحة 189
Basic & Clinical Pharmacology
Covers the important concepts students need to know about the science of pharmacology and its application to clinical practice. This edition has been extensively updated to provide expanded coverage of transporters, pharmacogenomics, and new drugs Delivers the knowledge and insight needed to excel in every facet of pharmacology!. Encompasses all aspects of medical pharmacology, including botanicals and over-the-counter drugs Major revisions of the chapters on immunopharmacology, antiseizure, antipsychotic, antidepressant, antidiabetic, anti-inflammatory, and antiviral drugs, prostaglandins, and central nervous system neurotransmitters New chapter on the increasingly relevant topic of cannabis pharmacology Each chapter opens with a case study, covers drug groups and prototypes, and closes with summary tables and diagrams that encapsulate important information Revised full-color illustrations provide more information about drug mechanisms and effects and help clarify important concepts Trade Name/Generic Name tables are provided at end of each chapter for easy reference when writing a chart order or prescription Includes descriptions of important new drugs released through May 2019 New and updated coverage of general concepts relating to recently discovered receptors, receptor mechanisms, and drug transporters
Barry's Introduction to Construction of Buildings ; 4th ed.
Based mainly on domestic and residential buildings—and filled with extensive illustrations throughout—this concise text is the ideal introduction to the subject of building construction. It provides the basic material that readers need in order to understand the construction process for the majority of low rise buildings. The book explains construction technology through the key functional and performance requirements for the main elements common to all buildings. With a strong focus on building efficiency and meeting the challenges posed by limiting the environmental impact of buildings, and new “at a glance” summaries allowing you to grasp the salient points of each chapter, readers will find the text fully up to date with the latest building regulations and construction technology. Deals with design, technology, site assembly, and environmental issues of domestic and residential buildings. Thoroughly updated, with particular attention paid to the concept of building efficiency and improved integration of the topics covered to match current student needs. New “at a glance” summaries at the beginning of each chapter.
Barriers and Biases in Computer-Mediated Knowledge Communication : And How They May Be Overcome
This books deals with computer-mediated cooperation and communication scenarios in teaching and learning situations, leisure activities (e.g. laypersons looking for expert information on the internet), and net-based communication at work. Such scenarios will become increasingly important. But the successful use of such computer-mediated settings is not trivial. Cooperative learning and work itself requires special skills and strategies. And the technical settings with sometimes restricted, sometimes new possibilities for communication add problems on top of the cooperation itself. What are the barriers in computer-mediated communication for cooperative learning and work? Which are the most relevant biases in computer-mediated information processing? Based on empirical research the contributors from psychology, education and computer sciences offer different perspectives on the nature and causes of such barriers.
Barile's clinical toxicology : Principles and mechanisms ; 3rd ed.
Examines the complex interactions associated with clinical toxicological events as a result of therapeutic drug administration or chemical exposure. Special emphasis is placed on signs and symptoms of diseases and pathology caused by toxins and clinical drugs. Includes the source, pharmacological and toxicological mechanism of action, detection and identification in body fluids, and treatment of exposure. An overview of protocols for managing various toxic ingestions, and the antidotes and treatments associated with their pathology, are discussed. In addition, effect of toxins on a limited number of body systems and drug-induced adverse drug reactions are also covered
Banks and shareholder value : An overview of bank valuation and empirical evidence on shareholder value for banks
In the German banking sector, management is continually increasing its focus on shareholder interests. This can be seen in the ambitious profitability targets set by management in this sector. Some municipalities are also putting increasing pressure on Landesbanks and saving banks, as members of the largest German banking group, to create greater financial value.
Banking on (artificial) intelligence : Navigating the realities of ai in financial services
Provides a tailored overview of what AI specifically means for financial services, a highly regulated yet also disrupted industry. it investigates the current state of AI applications in financial services today along with the state of funding and partnerships between tech and banking industries. it also examines the key pillars of responsible AI and the importance of keeping humans in the loop. the book takes a deep dive into the use cases in the financial services industry, the challenges and opportunities, and the fragmented regulatory landscape. how can we effectively assess risks, and balance innovation and customer centricity with trust in AI in financial services? can smaller organizations reap the benefits of the technology? how can institutions deploy AI responsibly and securely, and promote a fairer and more equitable future for more people?
Banking for Family Business: A New Challenge for Wealth Management
Hints of globalization have actually been around for several decades, even though they made only a modest impact; however, the availability of global capital and advances in communication technology have emp- sized the process of internationalization and the tools available to connect and integrate business activities to answer to more complex needs of c- ents. Moreover, the financial scandals and the review of mutual fund trade activity in the US by the Attorney General Elliot Spitzer have highlighted the importance to focus all efforts on renewing the confidence of prof- sional investors and their clients who have entrusted their capital to asset managers. Therefore, there is a growing need in the market to reinforce the concept of “Shared Positive Values” among the entire industry and among its stakeholders.
Bandwidth Extension of Speech Signals
Bandwidth Extension of Speech Signals provides discussion on different approaches for efficient and robust bandwidth extension of speech signals while acknowledging the influence of noise corrupted real-world signals. The book describes the theory and methods for quality enhancement of clean speech signals and distorted speech signals.
Balloon Kyphoplasty
This book focuses on balloon kyphoplasty and alter- tive minimally invasive treatments for stabilization of osteoporotic vertebral fractures. The optimal treatment of a patient with osteoporotic vertebral fractures requires an interdisciplinary - proach, and therefore our book draws on the expertise of orthopedic surgeons, traumatologists and neu- surgeons, and also includes a chapter on medical treatment.
Balancing Exploration and Exploitation by Creating Organizational Think Tanks
Key for successful knowledge management is a balance between exploration and exploitation. Danger arises when exploration is neglected in favour of exploitation since that may result in an organization which lacks innovation capability. In order to prevent this, an idea has been put forward in recent knowledge management research called ambidexterity, which means the simultaneous and balanced pursuing of both exploration and exploitations activities. Tatjana-Xenia Puhan follows up on this idea by concluding that ambidexterity need not necessarily be implemented in one single organization but can also be realised in a network of associated organizations. The interorganizational ambidexterity is based on co-specialisation: one organisation is devoted solely to exploration while associated organizations focus on their competences in exploitation. Furthermore, the author develops the concept of think tanks as organizations that concentrate on radical innovations while their network associates exploit this newly generated knowledge commercially.
Baculovirus : Methods and protocols
Provides up-to-date guidance on techniques used to work with baculoviruses and insect cells. The book provides basic methods to create recombinant baculoviruses, to improve productivity, to produce a variety of products, to purify products, to quantify baculovirus stocks or to quantify product produced, and it concludes with alternative uses of either baculovirus or insect cells as tools. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Bacteriophage therapy: From lab to clinical practice
Details new and updated experimental approaches for isolating, formulating, and engineering bacteriophage medicinal products. Authored by leading experts and written in the highly successful Methods in Molecular Biology series format, each chapter includes introductions to their respective topics, lists of the necessary materials and reagents, step-by-step reproducible laboratory protocols, and valuable tips for troubleshooting and avoiding known pitfalls.
Bacteriophage therapy : a potential solution for antibiotic resistance crisis
For many years, humans have been fighting with bacteria, in a matter of fact, bacteria have been winning for the last decade, becoming resistant to every weapon we have; The antibiotics. In order to win the fight humans had to think of alternative ways, like viruses. There is a special type of viruses that have been in a war with bacteria for millenniums, Bacteriophages. Bacteriophages (or phages), the most abundant viral entity of the planet. On the basis of their unique characteristics and anti-bacterial property, phages are being the freshly evaluated taxonomically. Phages replicate inside the host either by lytic or lysogenic mode after infecting and using the cellular machinery of a bacterium. Phage became an important agent for combating pathogenic bacteria in clinical treatments and its related research gained momentum. However, due to recent rise of bacterial resistance on antibiotics, applications of phage (phage therapy) become an unavoidable option of research. In this dissertation, the advantage and limitations of Bacteriophages for use in humans will be discussed. Furthermore, this dissertation deals with recent development of its application in the areas of biotechnology.
Bacteriocins : Ecology and Evolution
Microbes produce an extraordinary array of defense systems. These include bacteriocins, a class of antimicrobial molecules with narrow killing spectra, produced by bacteria. The book describes the diversity and ecological role of bacteriocins of Gram-positive and Gram-negative bacteria, presenting a new classification scheme for the former and a state-of-the-art look at the role of bacteriocins in bacterial communication. It discusses the molecular evolution of colicins and colicin-like bacteriocins, and provides a contemporary overview of archaeocins, bacteriocin-like antimicrobials produced by archaebacteria. Furthermore, various modeling (in silico) studies elucidate the role of bacteriocins in microbial community dynamics and fitness, delving into rock-paper-scissors competition and the counter-intuitive survival of the weakest. The book makes compelling reading for a multi-faceted scientific audience, including those working in the fields of biodiversity and biotechnology, notably in the human and animal health domain.
Bacterial signal transduction : Networks and drug targets
Interactions among different TCSs enable one system to respond to multiple signals, which is important for bacteria to minutely adjust themselves to complex environmental changes. Such interactions are found or predicted in various bacteria in this book. Over the past decade, a vast amount of exciting new information on the signal transduction pathway in bacteria has been brought to light. Reports on these develop› ments have been put together in this book, Bacterial Signal Transduction: Networks andDrug Targets. This book Offers an incentive for graduate students, academic scientists, and researchers in the pharmaceutical industry to further elucidate the TCS networks and apply them in the search for novel drugs.
Bacterial regulatory RNA : Methods and protocols
Details new and updated methods used for studying prokaryotic non-coding RNAs and their protein accomplices. Chapters detail discovery of ncRNAs, characterization of their structure, functions, and their interactomes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Bacterial Physiology : A Molecular Approach
The application of new molecular methodologies in the study of bacterial behaviour and cell architecture has enabled new revolutionary insights and discoveries in these areas. While this has also raised a number of scientific mysteries about bacteria, it certainly improved our understanding of these organisms as complex and adaptive entities rather than just simple tiny buckets of enzymes. The value of this recent knowledge in bacterial physiology is not only restricted to fundamental biology, but it also extends to biotechnology and drug-discovery disciplines where understanding cell behaviour and structure is essential for better exploitation of useful bacteria and effective eradication of harmful ones. This makes a new text accommodating recent developments in bacterial physiology highly relevant to a wide range of readership including those interested in basic and applied knowledge.
Bacterial Genomes and Infectious Diseases
This book imparts fundamental knowledge on the structure, organization, and evolution of bacterial genomes. The value and power of comparative genomics and proteomics, bioinformatics, microarrays, and knockout animal models in analyzing genomes, bacteria-host interactions and disease are demonstrated. Also discussed are the genomes of virulent and nonvirulent strains and species, origin and evolution of pathogens, different models of bacteria-host interactions, and diseases mechanisms.
Bacterial chromatin : Methods and protocols
Brings together new and updated methods to explore the structure and function of bacterial chromatin from molecular to the cellular scale. Chapters detail experimental protocols of in vivo and in vitro approaches, approaches to genome structure modeling, and data analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Azaheterocycles Based on -, ß-Unsaturated Carbonyls
Devoted to heterocyclizations of aliphatic and aromatic, -unsaturated carbonyls with various binucleophiles leading to three-, five-, six and seven-membered partially hydrogenated nitrogen-containing heterocycles. During the last decade interest in these classes of organic c- pounds has been experiencing a scientific renaissance owing to their significant role in biological processes in living cells and diverse effects on physiological activities. In addition, such compounds are also more prevalent from the vi- point of ''classical'' problems of organic chemistry, among them reactivity, chemo- and regioselectivity, tautomerism, conformational analysis and features of their electronic structure. The character of these problems in the case of partially hydrogenated heterocycles differs sufficiently from that for hetero- omatized and perhydrogenated heterocyclic compounds and investigations in this field very often lead to interesting and unusual results. Extensively characterized cyclocondensations of, -unsaturated carbonyls, their synthetic equivalents and their precursors are the most widespread, facile and generally valid pathway to dihydroazaheterocycles.
