الصفحة 18
الصفحة 18
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Multiscale Modeling : A Bayesian Perspective

The book is aimed at statisticians, applied mathematicians, and engineers working on problems dealing with multiscale processes in time and/or space, such as in engineering, finance, and environmetrics. The book will also be of interest to those working on multiscale computation research. The main prerequisites are knowledge of Bayesian statistics and basic Markov chain Monte Carlo methods. A number of real-world examples are thoroughly analyzed in order to demonstrate the methods and to assist the readers in applying these methods to their own work. To further assist readers, the authors are making source code (for R) available for many of the basic methods discussed herein.

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Multiscale fatigue crack initiation and propagation of engineering materials ; Structural integrity and microstructural worthiness : Fatigue crack growth behaviour of small and large bodies

This book elucidates the correlation of fatigue crack growth data to multiscale cracking, particularly to the understanding of micrographs influenced by mechanical disturbance and thermodynamic variables. Attention is given to the interpretation of test data by fatigue crack growth rate using two empirical parameters in consistence with the fracture control methodology currently used by industry.

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Multiscale Biomechanics and Tribology of Inorganic and Organic Systems : In memory of Professor Sergey Psakhie

This book gathers authoritative contributions concerning multiscale problems in biomechanics, geomechanics, materials science and tribology. It is written in memory of Sergey Grigorievich Psakhie to feature various aspects of his multifaceted research interests, ranging from theoretical physics, computer modeling of materials and material characterization at the atomic scale, to applications in space industry, medicine and geotectonics, and including organizational, psychological and philosophical aspects of scientific research and teaching as well

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Multi-Scale Approaches in Drug Discovery : From Empirical Knowledge to In silico Experiments and Back

Drug discovery is an expensive, time-consuming process and the modern drug discovery community is constantly challenged not only with discovering novel bioactive agents to combat resistance from known diseases and fight against new ones, but to do so in a way that is economically effective. Advances in both experimental and theoretical/computational methods envisage that the greatest challenges in drug discovery can be most successfully addressed by using a multi-scale approach, drawing on the specialties of a whole host of different disciplines. Multi-Scale Approaches to Drug Discovery furnishes chemists with the detail they need to identify drug leads with the highest potential before isolating and synthesizing them to produce effective drugs with greater swiftness than classical methods may allow. This significantly speeds up the search for more efficient therapeutic agents.

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Multirate Statistical Signal Processing

This book introduces a statistical theory for extracting information from signals that have di?erent sampling rates. This new theory generalizes the conventional (deterministic) theory of multirate systems beyond many of its constraints.Furthermore,itallowsfortheformulationofseveralnewproblems such as spectrum estimation, time-delay estimation and sensor fusion in the realm of multirate signal processing. I have arrived at the theory presented here by integrating concepts from diverse areas such as information theory, inverse problems and theory of - equalities. The process of merging a variety of concepts of di?erent origin results in both merits and shortcomings. The former include the fresh and - di?erentiated view of an amateur, providing scope of application. The latter include a lack of in-depth experience in each of the original ?elds. Granted, this may lead to gaps in continuity, however it goes without saying that a complete theory can seldom be achieved by one person and in a short time.

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Multiplicative Invariant Theory

Multiplicative invariant theory, as a research area in its own right within the wider spectrum of invariant theory, is of relatively recent vintage. The present text offers a coherent account of the basic results achieved thus far.. Multiplicative invariant theory is intimately tied to integral representations of finite groups. Therefore, the field has a predominantly discrete, algebraic flavor. Geometry, specifically the theory of algebraic groups, enters through Weyl groups and their root lattices as well as via character lattices of algebraic tori.

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Multiplicative Ideal Theory in Commutative Algebra : A Tribute to the Work of Robert Gilmer

This volume, a tribute to the work of Robert Gilmer, consists of twenty-four articles authored by his most prominent students and followers. These articles combine surveys of past work by Gilmer and others, recent results which have never before seen print, open problems, and extensive bibliographies.

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Multiple Stressors : A Challenge for the Future

This book publishes the Proceedings of the NATO Advanced Research Workshop on Multipollution Exposure and Risk Assessment, Ecotoxiclogical risk from multiple stressors covers any situation where org- isms are exposed to a combination of environmental stressors. These include physical and chemical pollutants as well as other stressors such as parasites and environmental impact (e. g. , climate change or habitat loss). The combi- tion of stressors can result in increased risk to organisms (either additive or synergistic effects) or decreased effects (protective or antagonistic effects). The multiple stressor challenge is an international, multi-disciplinary problem requiring an international, multi-disciplinary approach. The c- rent approach to multiple stressors is to examine one stressor at a time and assume additivity.

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Multiple Sclerosis: Autoimmunity and Management

Multiple sclerosis (MS) is an immune-mediated inflammatory disease that attacks myelinated axons in the central nervous system, destroying the myelin and the axon in variable degrees and producing significant physical disability within 20–25 years in more than 30% of patients. The hallmark of MS is symptomatic episodes that occur months or years apart and affect different anatomic locations. Also, see the Autoimmune Disorders: Making Sense of Nonspecific Symptoms slideshow to help identify several diseases that can cause a variety of nonspecific symptoms. MS is diagnosed on the basis of clinical findings and supporting evidence from ancillary tests. Treatment consists of immunomodulatory therapy for the underlying immune disorder and management of symptoms, as well as nonpharmacologic treatments, such as physical and occupational therapy. Disease-modifying therapies have shown beneficial effects in patients with relapsing MS, including reduced frequency and severity of clinical attacks. These agents appear to slow the progression of disability and the reduce accumulation of lesions within the brain and spinal cord.

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Multiple pregnancy

Multiple pregnancy affects 0.9-3.1% of births worldwide. Prevalence rates vary significantly due to differences in dizygotic twinning rates and use of assisted reproduction. Both maternal and fetal/neonatal complications are more common in multiple compared to singleton pregnancies, and there are specific problems for the fetuses related to monochorionicity. Multiple pregnancies require specialised and individualised care. Complicated multiple pregnancies should be managed in a tertiary care centre where there is additional expertise, such as the laser ablation needed to treat monochorionic monozygotic pregnancies with conjoined circulations. Cornerstones of management in pregnancy are the need for accurate fetal measurement to optimise dating of gestational age, and documentation of chorionicity. High-level ultrasound expertise is needed. The mothers need frequent assessment to detect hypertension and anemia, and early identification and management of preterm labour.

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Multiple Classifier Systems ; 7th International Workshop, MCS 2007, Prague, Czech Republic, May 23-25, 2007, Proceedings

These proceedings are a record of the Multiple Classifier Systems Workshop, MCS 2007, held at the Institute of Information Theory and Automation, Czech Academy of Sciences, Prague in May 2007. the workshop achieved its objective of bringing together researchers from diverse communities (neural networks, pattern rec- nition, machine learning and statistics) concerned with this research topic.

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Multiphase Reacting Flows : Modelling and Simulation

This book entitled ''Multiphase reacting flows: modelling and simulation'' contains the lecture notes of the CISM (International Centre for Mechanical Sciences) course held in Udine, Italy, on July 3-7, 2006, and it describes various modelling approaches for dealing with polydisperse multiphase reacting flows. A multiphase reacting system is characterized by the presence of multiple phases and in this book we focus on disperse multiphase systems, where one phase can be considered as a continuum, whereas the additional phases are dispersed in the continuous one. In other words, in this book we deal with multiphase systems constituted by particles, droplets or bubbles (i.e., solid particles suspended in a continuous liquid phase, liquid droplets in a gaseous phase, or gas bubbles in liquid.) The other important characteristic elements of the systems discussed in this book are the presence of one or more chemical reactions and the turbulent nature of the flow. The chemical reactions usually involve all the phases present in the system and might be responsible for the formation or disappearance of the disperse and/or continuous phases.

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Multiphase Flow Dynamics 3 : Turbulence, Gas Absorption and Release, Diesel Fuel Properties

Volume 3 is devoted to selected Chapters of the multiphase fluid dynamics that are important for practical applications. The state of the art of the turbulence modeling in multiphase flows is presented. As introduction, some basics of the single-phase boundary layer theory including some important scales and flow oscillation characteristics in pipes and rod bundles are presented. Then the scales characterizing the dispersed flow systems are presented. The description of the turbulence is provided at different level of complexity: simple algebraic models for eddy viscosity, algebraic models based on the Boussinesq hypothesis, modification of the boundary layer share due to modification of the bulk turbulence, modification of the boundary layer share due to nucleate boiling. Then the role of the following forces on the matematical description of turbulent flows is discussed: the lift force, the lubrication force in the wall boundary layer, and the dispersion force.

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Multiphase Flow Dynamics 2 : Thermal and Mechanical Interactions ; 3rd ed.

Multi-phase flows are part of our natural environment such as tornadoes, typhoons, air and water pollution and volcanic activities as well as part of industrial technology such as power plants, combustion engines, propulsion systems, or chemical and biological industry. The industrial use of multi-phase systems requires analytical and numerical strategies for predicting their behavior. In its third extended edition this book contains theory, methods and practical experience for describing complex transient multi-phase processes in arbitrary geometrical configurations. This book provides a systematic presentation of the theory and practice of numerical multi-phase fluid dynamics. In the present second volume the mechanical and thermal interactions in multiphase dynamics are provided. This third edition includes various updates, extensions, improvements and corrections.

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Multiphase Flow Dynamics 2 : Thermal and Mechanical Interactions ; 2nd ed.

This book provides a systematic presentation of the theory and practice of numerical multi-phase fluid dynamics. In the present second volume the mechanical and thermal interactions in multiphase dynamics are provided.

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Multiphase Flow Dynamics 1 : Fundamentals ; 3rd ed.

Multi-phase flows are part of our natural environment such as tornadoes, typhoons, air and water pollution and volcanic activities as well as part of industrial technology such as power plants, combustion engines, propulsion systems, or chemical and biological industry. The industrial use of multi-phase systems requires analytical and numerical strategies for predicting their behavior. In its third extended edition this monograph contains theory, methods and practical experience for describing complex transient multi-phase processes in arbitrary geometrical configurations, providing a systematic presentation of the theory and practice of numerical multi-phase fluid dynamics. This third edition includes various updates, extensions and improvements in all book chapters.

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Multiparadigm Programming in Mozart/Oz ; 2nd International Conference, MOZ 2004, Charleroi, Belgium, October 7-8, 2004, Revised Selected Papers

Oz's concurrency model yields simplicity and clarity (because Oz makes it easier to express complex programs with many interacting components), g- erality, and better interfaces (because the data?ow model automatically makes interfaces more lightweight). Constraint programming in Oz again yields simplicity and clarity (because theprogrammercanexpresswhatneedstobetrueratherthanthemorecomplex issue of how to make it true), and o?ers a powerful mathematical notation that is di?cult to implement on top of languages that do not support it natively. Mozart's distributed computing model makes for improved interfaces and eases the evolution of systems. In my own work, one of the most important concernsistobeabletoquicklyscaleupaprototypeimplementationintoalar- scale service that can run reliably on thousands of computers, serving millions of users.

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Multiobjective Problem Solving from Nature : From Concepts to Applications

he book focuses on how MOEAs and related techniques can be used to solve problems, particularly in the disciplines of science and engineering. Contributions by leading researchers show how the concepts of multiobjective optimization can be used to reformulate and resolve problems in broad areas such as constrained optimization, coevolution, classification, inverse modelling and design. The book is distinguished from other texts on MOEAs in that it is not primarily about the algorithms, nor specific applications, but about the concepts and processes involved in solving problems using a multiobjective approach. Each chapter contributes to the central, deep concepts and themes of the book: evaluating the utility of the multiobjective approach; discussing alternative problem formulations; showing how problem formulation affects the search process; and examining solution selection and decision making.

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Multimodality in architecture : Collaboration, technology and education

Examines multimodality in architecture and its impacts on collaborative, technical and educational processes or systems. Multimodality is becoming increasingly critical in contemporary architectural practice and education. Creative design teams face new challenges when they embrace new modes of communication, technology, and knowledge development processes. From diverse online modes of communication to shared digital environments, generative AI and advanced hardware solutions, new modes of information creation, sharing, and application are changing the ways architects and designers work. The book presents new research which empowers international researchers and designers to work more effectively in a diverse range of digital environments. Whether the readers are architects, teachers, students, or scholars, this book provides critical insights and practical tools for understanding and optimising processes in architecture and design.

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Multimodal Concepts for Integration of Cytotoxic Drugs

The first part of this book summarizes the rationale and the preclinical data for combined treatment with ionizing radiation and pharmaceutical agents. Individual chapters focus on different forms of combined treatment, with due consideration being given to a range of drugs and to emerging combinations with small molecules and antibodies, derived from recent advances in molecular oncology. The second part of the book comprises a series of disease-specific chapters in which the clinical results of combined modality treatment are presented. In addition, the topics of acute and late toxicity, supportive treatment and tolerance in elderly patients are reviewed.

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