الصفحة 18
الصفحة 18
Bioinformatics research and applications : 4th International Symposium, ISBRA 2008, Atlanta, GA, USA, May 6-9, 2008. Proceedings
This book constitutes the refereed proceedings of the Fourth International Symposium on Bioinformatics Research and Applications, ISBRA 2008, held in Atlanta, GA, USA in May 2008.
Bioinformatics of genome regulation and structure II
The conference was organized by the Laboratory of Theoretical Genetics, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia. The material covers the most recent topics in bioinformatics, including (i) regulatory genomic sequences: databases, knowledge bases, computer analysis, modeling, and recognition; (ii) large-scale genome analysis and functional annotation; (iii) gene structure detection and prediction; (iv) comparative and evolutionary genomics; (v) computer analysis of genome polymorphism and evolution; computer analysis and modeling of transcription, splicing, and translation; structural computational biology: structure- function organization of genomic DNA, RNA, and proteins; (vi) gene networks, signal transduction pathways, and genetically controlled metabolic pathways: databases, knowledge bases, computer analysis, and modeling; principles of organization, operation, and evolution; (vii) data warehousing, knowledge discovery and data mining; and (viii) analysis of basic patterns of genome operation, organization, and evolution.
Bioinformatics drug discovery
Quantitative tools are becoming increasingly important in order to understand complex cascade of signal transduction events, pathways or biochemical reactions. The book showcases how computational techniques and algorithms are applied to biological data analysis, interpretation, and modelling. It covers applications in drug design and discovery, immune systems, phylogenetic analysis and protein structures.
Biocombinatorial approaches for drug finding
Genome- and proteome-based research is generating a significant increase in the number of available drug targets. Correspondingly there is an increasing need for novel, diverse compounds, particularly based on natural compounds, as screening resource
Bioactive Molecules and Medicinal Plants
Use of medicinal plants is as old as human civilization and continuous efforts are being made to improve medicinal plants or produce their products in high amounts through various technologies. About 200,000 natural products of plant origin are known and many more are being identifed from higher plants and microorganisms. Some plant-based drugs have been used for centuries and there is no alternative medicine for many drugs, such as cardiac glycosides. However, natural products research was sidelined to pave the way for com- natorial chemistry, which was expected to produce large numbers of synthetic compounds for high-throughput screening (HTS). This line of work has failed to deliver desirable results. Moreover, it is not possible for all pharmaceutical companies and institutions to adopt costly HTS technology. Therefore, medi- nal plants and their bioactive molecules are always in demand and are a central point of research. While planning this book, we endeavored to incorporate - ticles that cover the entire gamut of current medicinal plants research.
Bioactive Marine Natural Products
Bioactive Marine Natural Products is the first book available that covers all aspects of bioactive marine natural products. It fills the void in the literature for bioactive marine natural products. The book covers various aspects of marine natural products and it is hoped that all the major classes of bioactive compounds are included. Different classes of marine organisms and the separation and isolation techniques are discussed. The chemistry and biology of marine toxins, peptides, alkaloids, nucleosides and prostanoids are discussed in detail. Biological, toxicological and clinical evaluations are also dealt with to ensure that the book may be adopted at any stage by any practicing organic chemist or biologist, working in academia or in R&D divisions of pharmaceutical companies. Each chapter in the book includes an abstract to highlight the major points discussed in the text and concluding remarks are given. References to books, monographs, review articles and original papers are provided at the end of each chapter.
Bioactive Heterocyles I
Bioactive Heterocycles I is a continuation of critical accounts about heterocyclic compounds within the series Topics in Heterocyclic Chemistry. The present volume provides comprehensive reviews of the chemistry and bioactivity of selected groups of heterocycles and natural products. … Overall, this book covers in detail several classes of bioactive heterocyclic compounds including selected natural products. The focus is on the most recent advances, and the clarity of the presentation is very good. It should be of interest to individuals interested in the discovery and synthesis of bioactive small molecules, including research scientists in academia and industry.
Big data-enabled internet of things
Covers analytical techniques for handling the huge amount of data generated by the Internet of Things, from architectures and platforms to security and privacy issues, applications, and challenges as well as future directions. The fields of Big Data and the Internet of Things (IoT) have seen tremendous advances, developments, and growth in recent years. The IoT is the inter-networking of connected smart devices, buildings, vehicles and other items which are embedded with electronics, software, sensors and actuators, and network connectivity that enable these objects to collect and exchange data. The IoT produces a lot of data. Big data describes very large and complex data sets that traditional data processing application software is inadequate to deal with, and the use of analytical methods to extract value from data. This edited book covers analytical techniques for handling the huge amount of data generated by the Internet of Things, from architectures and platforms to security and privacy issues, applications, and challenges as well as future directions.
Big Data Recommender Systems ; Vol.2 : Application Paradigms
Combines experimental and theoretical research on big data recommender systems to help computer scientists develop new concepts and methodologies for complex applications. It includes original scientific contributions in the form of theoretical foundations, comparative analysis, surveys, case studies, techniques and tools. First designed to generate personalized recommendations to users in the 90s, recommender systems apply knowledge discovery techniques to users’ data to suggest information, products, and services that best match their preferences. In recent decades, we have seen an exponential increase in the volumes of data, which has introduced many new challenges. recommender systems. Volume 2 covers a broad range of application paradigms for recommender systems over 22 chapters
Big Data Recommender Systems ; Vol.1 : Algorithms, Architectures, Big Data, Security and Trust
Combines experimental and theoretical research on big data recommender systems to help computer scientists develop new concepts and methodologies for complex applications. It includes original scientific contributions in the form of theoretical foundations, comparative analysis, surveys, case studies, techniques and tools.
Beginning jOOQ : Learn to Write Efficient and Effective Java-Based SQL Database Operations
Learn to use the jOOQ library to manage SQL database operations in Java and JVM applications. This book walks you through what JOOQ is, how to install and get started with it, and then gets you working with it. You will: Comparing equivalent features between Hibernate, JPA and jOOQ. Unlock the power of your SQL database with high performing, flexible and typesafe SQL queries. Seamlessly work with many different SQL database vendors without changing your code. Effortlessly generate Java code based on the content of your database. Write reactive SQL database access code with R2DBC. Integrating jOOQ into popular frameworks and platforms like Hibernate, Spring boot and Quarkus tools like IDEs. Testing jOOQ-based code with modern integration testing frameworks like TestContainers and Docker. Learn how to safely handle data access code within frameworks like the Java Persistence API (JPA)
Beginning deep learning with TensorFlow : Work with Keras, MNIST data sets, and advanced neural networks
Stats with an introduction to AI, where you’ll learn the history of neural networks and what sets deep learning apart from other varieties of machine learning. Discovery the variety of deep learning frameworks and set-up a deep learning development environment. Next, you’ll jump into simple classification programs for hand-writing analysis. Once you’ve tackled the basics of deep learning, you move on to TensorFlow 2 specifically. Find out what exactly a Tensor is and how to work with MNIST datasets. Finally, you’ll get into the heavy lifting of programming neural networks and working with a wide variety of neural network types such as GANs and RNNs. Deep Learning is a new area of Machine Learning research widely used in popular applications, such as voice assistant and self-driving cars. Work through the hands-on material in this book and become a TensorFlow programmer! You will: Develop using deep learning algorithms Build deep learning models using TensorFlow 2 Create classification systems and other, practical deep learning applications
Basic principles of drug discovery and development ; 2nd ed.
Presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields. Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics. Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborator’s fields.
Bacterial regulatory RNA : Methods and protocols
Details new and updated methods used for studying prokaryotic non-coding RNAs and their protein accomplices. Chapters detail discovery of ncRNAs, characterization of their structure, functions, and their interactomes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Bacterial Physiology : A Molecular Approach
The application of new molecular methodologies in the study of bacterial behaviour and cell architecture has enabled new revolutionary insights and discoveries in these areas. While this has also raised a number of scientific mysteries about bacteria, it certainly improved our understanding of these organisms as complex and adaptive entities rather than just simple tiny buckets of enzymes. The value of this recent knowledge in bacterial physiology is not only restricted to fundamental biology, but it also extends to biotechnology and drug-discovery disciplines where understanding cell behaviour and structure is essential for better exploitation of useful bacteria and effective eradication of harmful ones. This makes a new text accommodating recent developments in bacterial physiology highly relevant to a wide range of readership including those interested in basic and applied knowledge.
Autonomous intelligent systems : Agents and data mining ; International workshop, AIS-ADM 2005
This book constitutes the refereed proceedings of the International Workshop on Autonomous Intelligent Systems: Agents and Data Mining, AIS-ADM 2005, held in St. Petersburg, Russia in June 2005. The 17 revised full papers presented together with 5 invited papers and the abstract of an invited talk were carefully reviewed and selected from 29 submissions. The papers are organized in topical sections on agent-based data mining issues, ontologies and Web mining, and applications and case studies.
Asymptotic Theory of Statistics and Probability
An encyclopedic treatment of classic as well as contemporary large sample theory, dealing with both statistical problems and probabilistic issues and tools. It is written in an extremely lucid style, with an emphasis on the conceptual discussion of the importance of a problem and the impact and relevance of the theorems. The book has 34 chapters over a wide range of topics, nearly 600 exercises for practice and instruction, and another 300 worked out examples. It also includes a large compendium of 300 useful inequalities on probability, linear algebra, and analysis that are collected together from numerous sources, as an invaluable reference for researchers in statistics, probability, and mathematics.
Artificial neural networks in Pattern Recognition ; 3d IAPR Workshop, ANNPR 2008 Paris, France, July 2-4, 2008 Proceedings
Constitutes the refereed proceedings of the Third TC3 IAPR Workshop on Artificial Neural Networks in Pattern Recognition, ANNPR 2008, held in Paris, France, in July 2008.
Artificial intelligence-based Internet of things systems
Discusses the evolution of future generation technologies through Internet of Things (IoT) in the scope of Artificial Intelligence (AI). The main focus of this volume is to bring all the related technologies in a single platform, so that undergraduate and postgraduate students, researchers, academicians, and industry people can easily understand the AI algorithms, machine learning algorithms, and learning analytics in IoT-enabled technologies. This book uses data and network engineering and intelligent decision support system-by-design principles to design a reliable AI-enabled IoT ecosystem and to implement cyber-physical pervasive infrastructure solutions. This book brings together some of the top IoT-enabled AI experts throughout the world who contribute their knowledge regarding different IoT-based technology aspects. Addresses the complete functional framework workflow in AI-enabled IoT ecosystem; Presents intelligent object identification and object discovery through the IoT ecosystem and its implications to the real world ;Explores security and privacy issues and trustworthy machine learning related to data-intensive technologies in AI-based IoT ecosystems.
Artificial intelligence in medicine ; 11th Conference on artificial intelligence in medicine in Europe, AIME 2007, Amsterdam, The Netherlands, July 7-11, 2007, Proceedings
This book contains development of theory, systems, and applications of AI in medicine, including the exploitationof AI approachesto molecularmedicine and biomedical informatics.
