الصفحة 172
الصفحة 172
An introduction to pharmacovigilance ; 2nd ed.
Designed to aid the rapid understanding of the key principles of pharmacovigilance. Packed full of examples illustrating drug safety issues it not only covers the processes involved, but the regulatory aspects and ethical and societal considerations of pharmacovigilance. Covering the basics step-by-step, this book is perfect for beginners and is essential reading for those new to drug safety departments and pharmaceutical medicine students. The second edition is thoroughly revised and updated throughout and includes a new chapter on clinical aspects of pharmacovigilance.
An introduction to ontology engineering
Provides the reader with a comprehensive introductory overview of ontology engineering. A secondary aim is to provide hands-on experience in ontology development that illustrate the theory. The book is divided into three blocks: Block I: logic foundations for ontologies both regarding the languages (mainly First Order predicate Logic, Description Logics, and OWL) and automated reasoning. Block II: developing good ontologies with methods and methodologies, the top-down approach with foundational ontologies, and the bottom-up approach to extract as much useful content as possible from legacy material. Block III: advanced topics with a selection of areas of specialisation, including Ontology-Based Data Access, the interaction between ontologies and natural languages (multilingual ontologies, controlled natural language), and advanced modelling with additional language features (fuzzy and temporal ontologies)
An introduction to medicinal chemistry
Providing an introduction to medicinal chemistry, this resource covers basic principles and background, and describes the general tactics and strategies involved in developing an effective drug
An Introduction to Mathematics of Emerging Biomedical Imaging
Biomedical imaging is a fascinating research area to applied mathematicians. Challenging imaging problems arise and they often trigger the investigation of fundamental problems in various branches of mathematics. This is the first book to highlight the most recent mathematical developments in emerging biomedical imaging techniques. The main focus is on emerging multi-physics and multi-scales imaging approaches. For such promising techniques, it provides the basic mathematical concepts and tools for image reconstruction. Further improvements in these exciting imaging techniques require continued research in the mathematical sciences, a field that has contributed greatly to biomedical imaging and will continue to do so.
An Introduction to Markov Processes
Provides a more accessible introduction than other books on Markov processes by emphasizing the structure of the subject and avoiding sophisticated measure theoryLeads the reader to a rigorous understanding of basic theory
An Introduction to Language Processing with Perl and Prolog : An Outline of Theories, Implementation, and Application with Special Consideration of English, French, and German
This book teaches the principles of natural language processing, first covering linguistics issues such as encoding, entropy, and annotation schemes; defining words, tokens and parts of speech; and morphology. It then details the language-processing functions involved, including part-of-speech tagging using rules and stochastic techniques; using Prolog to write phase-structure grammars; parsing techniques and syntactic formalisms; semantics, predicate logic and lexical semantics; and analysis of discourse, and applications in dialog systems. The key feature of the book is the author's hands-on approach throughout, with extensive exercises, sample code in Prolog and Perl, and a detailed introduction to Prolog. The reader is supported with a companion website that contains teaching slides, programs, and additional material.
An Introduction to Infinite-Dimensional Analysis
In this revised and extended version of his course notes from a 1-year course at Scuola Normale Superiore, Pisa, the author provides an introduction – for an audience knowing basic functional analysis and measure theory but not necessarily probability theory – to analysis in a separable Hilbert space of infinite dimension.Starting from the definition of Gaussian measures in Hilbert spaces, concepts such as the Cameron-Martin formula, Brownian motion and Wiener integral are introduced in a simple way. These concepts are then used to illustrate some basic stochastic dynamical systems (including dissipative nonlinearities) and Markov semi-groups, paying special attention to their long-time behavior: ergodicity, invariant measure. Here fundamental results like the theorems of Prokhorov, Von Neumann, Krylov-Bogoliubov and Khas'minski are proved. The last chapter is devoted to gradient systems and their asymptotic behavior.
An Introduction to Global Spectral Modeling
Numerical weather prediction is receiving increased attention as weather forecasters aim to improve the numerical models used to forecast the weather. This is a textbook on global spectral modeling, which is an important component for global weather forecasts at numerous operational centers. This book covers all areas of model development including numerical analysis, treatment of clouds, mountains, radiation, precipitation processes, and the surface layers over land and the ocean. The objectives of this book are to provide a systematic and sequential background for students, researchers, and operational weather forecasters in order to develop comprehensive weather forecast models. This is designed for a one semester introductory graduate level course on weather prediction methodologies. As a prerequisite it requires a basic background in meteorology, applied mathematics, and numerical analysis.
An introduction to generative drug discovery
Describes the state‑of‑the‑art methods and applications for de novo design of drug candidates using generative chemistry models as well as the ethical aspects of this technology. It will provide a foundation for those new to the field as well as those that may already have some experience of its utility. With contributions from scientists in both academia and industry ‘Introduction to Generative Drug Discovery’ may represent one of the earliest if not the first book to focus on this topic.
An Introduction to continuous-time stochastic processes : Theory, models, and applications to finance, biology, and medicine
This book is introduction to the theory of continuous-time stochastic processes. A balance of theory and applications, the work features concrete examples of modeling real-world problems from biology, medicine, industrial applications, finance, and insurance using stochastic methods. No previous knowledge of stochastic processes is required. Key topics covered include: * Interacting particles and agent-based models: from polymers to ants * Population dynamics: from birth and death processes to epidemics * Financial market models: the non-arbitrage principle * Contingent claim valuation models: the risk-neutral valuation theory * Risk analysis in insurance
An introduction to clinical trials
An Introduction to clinical trials is a concise step-by-step guide to the principles and practices of clinical trials for those studying clinical trials or new to working on one. Clinical trials are critical to the progress of medicine and improving healthcare / as they evaluate whether new treatments and interventions work. They are also complex / multidisciplinary projects that integrate science / ethics / and legal requirements in the conduct of medical research.
An illustrated guide to oral histology
Delivers a collection of high-definition histological and pathological images, presenting both diseased and normal oral tissues. also includes core topics such as: An introduction to tooth development, including the bud, cap, early bell, and late bell stages A thorough exploration of enamel, dentin, cementum and dental pulp A discussion of the periodontal ligament, including alveolar crest fibers, horizontal, oblique, apical, and inter-radicular fibers, transseptal fibers, and gingival fibers A guide to alveolar bone, oral mucosa, and salivary glands Perfect for postgraduate dental students, An Illustrated Guide to Oral Histology will also be useful to undergraduate dental students, and those looking to improve their understanding of the microscopic structure of dental tissues and their pathologies.
An ecological and societal approach to biological control
Biological control is among the most promising methods for control of pests (including vectors), diseases and weeds. In this book ecological and societal aspects are for the first time treated together. In an ecological approach the aim is to evaluate the significance of certain biological properties like biodiversity and natural habitats. Also, it is important to see biological control from an organic (or ecological) farming point of view. In a societal approach terms like ‘consumer’s attitude’, ‘risk perception’, ‘learning and education’ and ‘value triangle’ are recognised as significant for biological production and human welfare.
An Atlas of Radioscopic Catheter Placement for the Electrophysiologist
Atlas of Radioscopic Catheter Placement for the Electrophysiologist is unique because it is the first book that provides a teaching tool for fellows in training, allied health professionals and accomplished electrophysiologists on relevant X-ray views commonly encountered in different electrophysiology procedures, and how these views correlate with cardiac anatomy.
An assessment framework for compliance with international space law and norms : Promoting equitable access and Use of space for emerging actors
proposes a framework for assessing countries’ levels of compliance with international space law and norms. It begins by exploring the development of two movements – the evidence-based policymaking and programming movement, and the rise of ratings and rankings research – and their growth across various disciplines. The analysis suggests that such efforts are useful in gauging the behavior of countries in space according to how well they adhere to existing space law and norms. To date, there is no comprehensive, periodic, and systematic measure of countries’ efforts to comply with space law and norms; this work endeavors to fill that gap by offering a framework in which to assess compliance.
An architecture of the Ozarks
Marlon Blackwell is a passionate polemicist. He's also a very gifted architect. The projects in this first monograph on the "radical ruralist," as touted by the Royal Institute of British Architects, offer a new architectural language that at once celebrate the vernacular and transgress the boundaries of the conventional
An American scientist on the research frontier : Edward Morley, community, and radical ideas in nineteenth-century science
This important examination of Morley’s struggle for personal and professional legitimacy extends and transforms our understanding of science during a foundational period, and leads to a number of unique conclusions that are vital to the literature and historiography of science.
Amino acid biosynthesis : Pathways, regulation and metabolic engineering
Amino Acids Biosynthesis presents the current knowledge of fundamental as well as applied microbiology of amino acids. Topics discussed are the amino acid biosynthetic pathways, their genetic and biochemical regulation, transport of amino acids and genomics of producing microorganisms. The characterization of the control mechanisms of amino acid biosynthesis has revealed insights into principles of genetic and biochemical regulation, such as transcriptional regulators and a new class of regulatory elements, the riboswitch. The volume further deals with the metabolic engineering of microorganisms for the biotechnological production of amino acids for use as pharmaceuticals and, particularly, as food and feed additives.
Ambient intelligence for scientific discovery : Foundations, theories, and systems
Many difficult scientific discovery tasks can only be solved in interactive ways, by combining intelligent computing techniques with intuitive and adaptive user interfaces. It is inevitable to use human intelligence in scientific discovery systems: human eyes can capture complex patterns and relationships, along with detecting the exceptional cases in a data set; the human brain can easily manipulate perceptions to make decisions. Ambient intelligence is about this kind of ubiquitous and autonomous human interaction with information. Scientific discovery is a process of creative perception and communication, dealing with questions like: how do we significantly reduce information while maintaining meaning, or how do we extract patterns from massive data and growing data resources. Originating from the SIGCHI Workshop on Ambient Intelligence for Scientific Discovery, this state-of-the-art survey is organized in three parts: new paradigms in scientific discovery, ambient cognition, and ambient intelligence systems. Many chapters share common features such as interaction, vision, language, and biomedicine.
Amazing numbers in biology
With hundreds of tables and over 10,000 entries anyone who works or studies in the life sciences or those with a curious mind will find exact answers to many questions requiring comparative data. This book is a clearly laid out presentation of the plain facts of life from all areas of biology. None of those figures or superlatives that might seem exotic to the layman is left out. Biology comes alive by this comprehensive references work.
