الصفحة 17
الصفحة 17
Drug delivery trends ; Vol. 3 : Expectations and realities of multifunctional drug delivery systems
Examines a drift in the pharmaceutical field across the wide range of dosage forms, drug delivery systems (micro and nanoparticulate), at the regulatory front and on new types of therapies in the market. This book covers the challenges on drug delivery systems in terms of preclinical and current ways of determining quality and the options to solve the challenges associated with this. Most small-medium scale industries and academics struggle with initial regulatory challenges so a detailed discussion on regulatory trend covers the necessary basic understanding of regulatory procedures and provides the required guidance.
Drop acid
Our most respected scientific literature is bursting with evidence that elevated uric acid levels lie at the root of many pervasive health conditions, but mainstream medicine for the most part remains unaware of this connection. This is especially alarming because many people don’t know they are suffering from sky-high levels, putting them at risk for developing or exacerbating potentially life-threatening illnesses.
Drawing the Ground - Landscape Urbanism Today : The Work of Palmbout Urban Landscapes
Documents some fifteen projects organized into six thematic blocks, including such extensive projects as Amsterdam Ijburg, a design for an urban extension to Amsterdam with a total area of 450 hectares, 18,000 residences, 100,000 square meters of office space, 30,000 square meters of stores, and other facilities, and Maastricht Belvedere, a restructuring of 280 hectares of a former industrial site with 4,000 residences, 100,000 square meters of office space, parking lots, and a vehicle bridge.
Drawing Ideas
Focuses on the three key types of drawing, explanatory sketches, notational sketches and visual narratives that help designers think through and communicate their ideas. Through these three fundamentals, Drawing Ideas provides a thorough course in creating clear graphic layouts and diagrams, including expressive human forms, thumbnailing a process, adding effective colour and text and more. In addition, a drawing boot camp provides a refesher course in accurately drawing geometric forms. By getting back to the basics, readers will not only benefit from updated freehand drawing skills, but will also succeed in presenting and explaining their drawings and designs to others.
Drawing Climate : Visualising Invisible Elements of Architecture
Investigates the history, theory and applications of climatic design in the built environment examining architecture and landscapes from various time periods. Based on a collaboration between the University of Sydney and the National University of Singapore, the book brings together contributing authors from Australia, Singapore, and the United States.
Drawing Architecture : The beginner's guide to drawing and painting buildings
A comprehensive and practical guide full of advice and inspiration for anyone wishing to capture the beauty of the urban landscape. The wonderful thing about drawing buildings is that, wherever you travel around the globe, you will never be short of subjects to inspire you. From the most elaborate of Renaissance cathedrals, through to the humble garden shed, you will always be able to practise your skills and learn a few techniques in the process. This hands-on and inspirational book will encourage you to meet the exciting challenges of drawing and painting buildings using a variety of media and a wide range of techniques, including pencil, pen, graphite powder, watercolour, water-soluble pencils and Indian ink. As you work through this book, you will look at materials and their qualities then move on to explore how to put these materials to best use when drawing specific types of building. You will be led gently through levels of learning, with easy and more challenging exercises progressing your knowledge and developing your skills. As the book is divided into discrete sections, you can dip in to a particular type of building that you wish to draw, and use the information and illustration provided, while extended teaching exercises take you through the way the author approaches composing and completing a drawing.
DNA Methylation, Epigenetics and Metastasis
Provides an outline of the epigenetic mechanisms involved in cancer progression and the generation of metastasis. This book describes the tumor suppressor genes undergoing transcriptional silencing by CpG island promoter hypermethylation in the different tumor types of the human anatomy and their association with tumoral behaviour
DNA Methylation : Development, Genetic Disease and Cancer
It has become apparent that the genomes of many organisms are characterized by unique patterns of DNA methylation which can differ from genome segment to genome segment and cell type to cell type. These patterns can be instrumental in determining cell type and function. Thus, it is not surprising that studies on the role of DNA methylation now occupy center stage in many fields of biology and medicine such as developmental biology, genetic imprinting, genetic disease, tumor biology, gene therapy, cloning of organisms and others. Once again, basic research in molecular biology has provided the essential foundation for investigations of biomedical problems.
Diverse Roles of Integrin Receptors in Articular Cartilage
Recent studies from the authors' laboratory and from other leading groups have shown that ß1-integrins are essential for cell signalling and communication in chondrocytes. Furthermore, ß1-integrins function as mechanoreceptors in the chondrocyte mechanotransduction pathway. Their expression is therefore essential for maintaining the chondrocyte phenotype, preventing chondrocyte apoptosis and regulating chondrocyte-specific gene expression. This book volume summarizes the work that the authors have done on ß1-integrins over the last 18 years and focuses on the expression and regulation of these proteins in chondrocytes and their role in the context of the unique function of chondrocytes within articular cartilage.
Distributed embedded systems : Design, middleware and resources ; IFIP 20th World computer congress, TC10 Working conference on distributed and parallel embedded systems (DIPES 2008), September 7-10, 2008, Milano, Italy
The IFIP series publishes state-of-the-art results in the sciences and technologies of information and communication. The principal aim of the IFIP series is to encourage education and the dissemination and exchange of information about all aspects of computing.
Distributed and Parallel Systems : Cluster and Grid Computing
DAPSY (Austrian-Hungarian Workshop on Distributed and Parallel Systems) is an international conference series with biannual events dedicated to all aspects of distributed and parallel computing. DAPSY started under a different name in 1992 (Sopron, Hungary) as regional meeting of Austrian and Hungarian researchers focusing on transputer-related parallel computing; a hot research topic of that time. A second workshop followed in 1994 (Budapest, Hungary). As transputers became history, the scope of the workshop widened to include parallel and distributed systems in general and the 1st DAPSYS in 1996 (Miskolc, Hungary) reflected the results of these changes.
Dissecting Discrimination : Identifying Its Various Faces and Their Sources
This book examines the phenomenon of discrimination using a descriptive approach. Discrimination is omnipresent, whether it is people who discriminate against other people or, more recently, also machines that discriminate against people. The first part of the analysis employs decision theory on discrimination, leading to two fundamental subtypes: taste-based discrimination and statistical discrimination. The second part links taste-based discrimination to social identity theory, demonstrates that not all taste-based discrimination is ultimately statistical discrimination, and reveals the evolutionary origins of our tastes.
Disorders due to addiction and its therapy in Syria
Addiction is a broad and important concept that has a lot of bad consequences, the goal of our research is to talk at an overview of all its types in order to raise public health awareness, addiction is not limited to narcotic substances, but until there is a behavioral type that includes getting used to harmful habits, we as pharmacists will focus on drug dependence and its mechanism, which many patients suffer from its disorders...
Disfluency and Proficiency in Second Language Speech Production
This book explores the concept of disfluency in speech production, particularly as it occurs in the context of second language acquisition. Drawing on examples from learner speech at three levels (beginner, intermediate and advanced), the author argues that acquiring target language norms for performing disfluency is essential to an individual being recognized as fluent in a language by fellow-speakers. Starting with a survey of the psycholinguistic research in this area, he then applies a sociolinguistic lens to examine how a learner's social and educational background impacts the types of disfluencies in their speech.
Discovery Science ; 11th International Conference, DS 2008, Budapest, Hungary, October 13-16, 2008. Proceedings
This book constitutes the refereed proceedings of the 11th International Conference on Discovery Science, DS 2008, held in Budapest, Hungary, in October 2008, co-located with the 19th International Conference on Algorithmic Learning Theory, ALT 2008.
Discovering Mathematics with Magma : Reducing the Abstract to the Concrete
This volume celebrates the first decade of the Computer Algebra system Magma. With a design based on the ontology and semantics of algebra, Magma enables users to rapidly formulate and perform calculations in the more abstract parts of mathematics. The book range over much of Magma's coverage of algorithmic algebra: from number theory and algebraic geometry, via representation theory and group theory to some branches of discrete mathematics and graph theory. A basic introduction to the Magma language is given in an appendix. The book is simultaneously an invitation to learn a new programming language in the context of contemporary research problems, and an exposition of the types of problem that can be investigated using computational algebra.
Digitization of the management accounting function : A case study analysis on manufacturing companies
Analyzes the impact of digitization on management accounting in five manufacturing companies. It is one of the first in-depth empirical studies on the intersection of management accounting and digitization. The study suggests that there are two archetypes of digitization of the management accounting function. The first archetype emphasizes top-down-driven changes that aim to enhance efficiency, such as conducting tasks with a higher degree of automation in a leaner structure with fewer resources. The second archetype is strongly driven and initiated by employees in the management accounting function (bottom-up). The focus is on improving the use of data by applying innovative analytics methods, integrating additional sources of data, and benefiting from new technologies like artificial intelligence. The results of the study also indicate that digitization of the management accounting function is mostly in line with the overall company strategy.
Digital Towns : Accelerating and Measuring the Digital Transformation of Rural Societies and Economies
This book explores the digital transformation of small and rural towns, in particular, how to measure the evolution and development of digital towns. In addition to access to resources, competition from urban and global markets, and population trends, rural communities present lesser access and use of digital technologies and have lower digital competencies and skills than their urban counterparts. Consequently, they experience less beneficial outcomes from increased digitalisation than urban areas. This book defines what a digital town is and explores digitalisation from the perspective of the four basic economic sectors in towns - individuals and households, businesses, the public sector, and civil society - and three types of enabling infrastructure - digital connectivity, education, and governance.
Digital Timing Measurements : From Scopes and Probes to Timing and Jitter
As many circuits and applications now enter the Gigahertz frequency range, accurate digital timing measurements have become crucial in the design, verification, characterization, and application of electronic circuits. To be successful in this endeavour, an engineer needs a knowledge base covering instrumentation, measurement techniques, signal integrity, jitter and timing concepts, and statistics. Very often even the most experienced digital test engineers, while mastering some of those subjects, lack systematic knowledge or experience in the high speed signal area.
Digital Phase Lock Loops : Architectures and Applications
This exciting new book covers various types of digital phase lock loops. It presents a comprehensive coverage of a new class of digital phase lock loops called the time delay tanlock loop (TDTL). It also details a number of architectures that improve the performance of the TDTL through adaptive techniques that overcome the conflicting requirements of the locking rage and speed of acquisition. These requirements are of paramount importance in many applications including wireless communications, consumer electronics and others. Digital Phase Lock Loops then illustrates the process of converting the TDTL class of digital phase lock loops for implementation on an FPGA-based reconfigurable system. These devices are being utilized in software-defined radio, DSP-based designs and many other communication and electronic systems to implement complex high-speed algorithms.
