الصفحة 17
الصفحة 17
Chromosomal alterations : Methods, results and importance in human health
Cytogenetics is a very important research tool in basic and applied research. The uses of cytogenetics in human-population monitoring, in biological dosimetry in radiation accidents and in astronauts and as a predictive measure of cancer are topics discussed in this book. The book will help the reader to better understand cytogenetics and the intricacies of the methodology. The different methods of fluorescence in situ hybridization are discussed and the results achieved are presented. The book provides a comprehensive review of basic and applied aspects of cytogenetics and therefore will be of interest to all who are interested in chromosomes and their alterations by different types of mutagens, including chemical mutagens and ionizing and nonionizing radiation, with special reference to electromagnetic fields.
Children in Tort Law Part II : Children as Victims
Since children are not as capable as adults to perceive the risks involved in many situations of daily life, they are at a high risk of suffering personal injuries, mainly resulting from home, school and traffic accidents. From the tort law perspective, this requires a specific treatment of children as victims. For the last few decades some legal systems have been trying to find new solutions for a better protection of children, while other legal systems still follow more traditional rules. After having tackled the problems concerning the position of children as tortfeasors in a previous book, in this book the same working team deals with the problems related to the position of children as victims. This book analyses both the traditional solutions found in some legal systems and the newer solutions offered by others and devotes specific attention to damage issues, apportionment of damage and insurance problems when the victim is a child.
Chernobyl: Catastrophe and Consequences
The long-term effects of the Chernobyl incident on the environment are still becoming apparent, twenty years after the event. This book, written by two researchers with frontline experience in this field, provides a detailed review of these over a wide range of ecosystems. It also discusses the responses and countermeasures utilised to combat the effects of the accident, as well as considering the health, social, psychological and economic impacts on the human population. Chernobyl - Catastrophe and Consequences / provides a comprehensive assessment of the Chernobyl accident and its long-term consequences draws on the most recent measurements of contamination in the terrestrial and aquatic food chains / discusses the sociological consequences of such disasters in detail / This book adds valuable weight to the debate about the environmental cost of nuclear power and the issue of nuclear safety.
Chernobyl - What Have We Learned? : The Successes and Failures to Mitigate Water Contamination Over 20 Years
Twenty million people have been exposed to Chernobyl radionuclides through the Dnieper River aquatic pathways. This book presents a 20-year historical overview and comprehensive study results of the aquatic environment affected by the 1986 Chernobyl nuclear accident. During this time, many water quality management practices and countermeasures were enacted. The book presents in-depth analyses of these water remediation actions, using current science and mathematical modeling, and discusses why some were successful, but many others failed. The chapter entitled Where Do We Go From Here? incorporates a comprehensive discussion of the planned New Safe Confinement (NSC) structure to cover the Chernobyl plant. The book closes with a summary and conclusions drawn from these analyses, making it a valuable reference tool for the future. This book will be of interest to engineers, scientists, decision-makers, and those involved in radiation protection and radioecology, environmental protection and risk assessment, water remediation and mitigation measures, and radioactive waste disposal. In addition, the detailed, almost day-to-day, emergency responses to the Chernobyl accident described in this book will also be useful to people developing emergency and long-term responses to accidental or intentional (by terrorists) releases of radionuclides, toxic chemicals and biological agents.
Chemometrics and Cheminformatics in Aquatic Toxicology
Chemometrics and Cheminformatics in Aquatic Toxicology delivers an exploration of the existing and emerging problems of contamination of the aquatic environment through various metal and organic pollutants, including industrial chemicals, pharmaceuticals, cosmetics, biocides, nanomaterials, pesticides, surfactants, dyes, and more. The book discusses different chemometric and cheminformatic tools for non-experts and their application to the analysis and modeling of toxicity data of chemicals to various aquatic organisms.
Chemistry for pharmacy students : General, organic and natural product chemistry ; 2nd ed.
Opens with an overview of the general aspects of chemistry and their importance to modern life, with emphasis on medicinal applications. The text then moves on to discuss the concepts of atomic structure and bonding and the fundamentals of stereochemistry and their significance to pharmacy in relation to drug action and toxicity. Various aspects of organic functional groups, organic reactions, heterocyclic chemistry, nucleic acids and their pharmaceutical importance are then covered in subsequent chapters, with the final chapter dealing with drug discovery and development, and natural product chemistry. Provides a student-friendly introduction to the main areas of chemistry required by pharmacy degree courses. Written at a level suitable for non-chemistry students in pharmacy, but also relevant to those in life sciences, food science, and the health sciences Includes learning objectives at the beginning of each chapter Focuses on the physical properties and actions of drug molecules
Chemistry and Safety of Acrylamide in Food
Specifically covered are the following aspects: exposure from the environment and the diet; biomarkers of exposure; risk assessment; epidemiology; mechanism of formation in food; biological alkylation of amino acids, peptides, proteins, and DNA by acrylamide and its epoxide metabolite glycidamide; neurotoxicity, reproductive toxicity, and carcinogenicity; protection against adverse effects; and possible approaches to reducing levels in food. Cross-fertilization of ideas among several disciplines in which an interest in acrylamide has developed, including food science, pharmacology, toxicology, and medicine, will provide a better understanding of the chemistry and biology of acrylamide in food, and can lead to the development of food processes to decrease the acrylamide content of the diet.
Chemicals as Intentional and Accidental Global Environmental Threats
The book contains fields of ecology, chemistry, medicine, epidemiology, public health, toxicology, risk assessment, environmental protection and management, modelling, environmental remediation technologies came together to discuss the chemicals threats for the global environment. The intentional or accidental release of chemicals into environment poses a global threat to public health and security.
Chemical residues in food from animal produce
One Health' is an approach to designing and implementing programmers, policies, legislation and research in which multiple sectors communicate and work together to achieve better public health outcomes . The areas of work in which a One Health approach is particularly relevant include food safety, the control of zoo noses (diseases that can spread between animals and humans, such as flu, rabies and Rift Valley Fever), and combating antibiotic resistance (when bacteria change after being exposed to antibiotics and become more difficult to.
Characteristics Finite Element Methods in Computational Fluid Dynamics
This book details a systematic characteristics-based finite element procedure to investigate incompressible, free-surface and compressible flows. The fluid dynamics equations are derived from basic thermo-mechanical principles and the multi-dimensional and infinite-directional upstream procedure is developed by combining a finite element discretization of a characteristics-bias system with an implicit Runge-Kutta time integration. For the computational solution of the Euler and Navier Stokes equations, the procedure relies on the mathematics and physics of multi-dimensional characteristics. As a result, the procedure crisply captures contact discontinuities, normal as well as oblique shocks, and generates essentially non-oscillatory solutions for incompressible, subsonic, transonic, supersonic, and hypersonic inviscid and viscous flows.
Chance Rules : An informal guide to probability, risk and statistics
This second edition of Chance Rules again recounts the story of chance through history and the various ways it impacts on our lives. Here you can read about the earliest gamblers who thought that the fall of the dice was controlled by the gods, as well as the modern geneticist and quantum theory researcher trying to integrate aspects of probability into their chosen speciality. Example included in the first addition such as the infamous Monty Hall problem, tossing coins, coincidences, horse racing, birthdays and babies remain, often with an expanded discussion, in this edition. Additional material in the second edition includes, a probabilistic explanation of why things were better when you were younger, consideration of whether you can use probability to prove the existence of God, how long you may have to wait to win the lottery, some court room dramas, predicting the future, and how evolution scores over creationism. Chance Rules lets you learn about probability without complex mathematics.
Chance : The life of games and the game of life
With its many easy-to-follow mathematical examples, this book takes the reader on an almost chronological trip through the fascinating and amazing laws of chance, omnipresent in the natural world and in our daily lives. Along the route many fascinating topics are discussed, such as: challenging probability paradoxes; "paranormal" coincidences; game odds; causes and effects; interpretation of opinion polls; winning chances as a game proceeds; the nature of randomness; entropy and randomness; randomness in life; algorithmic complexity and the undecidability of randomness; possibilities and limitations of learning the laws of a Universe immersed in chance events. This charming book will inform and entertain the scientist and non-scientist alike.
Chalcogenocarboxylic acid derivatives
Chalcogenocarboxylic acid derivatives are a large class of compounds including more than one chalcogenocarboxyl group in which one or two oxygen atoms of the carboxyl group are replaced with sulfur, selenium or tellurium atoms. The chemistry of metal chalcogenocarboxylates has not been explored extensively as that of carboxylates and dithiocarbamates. This volume presents a comprehensive overview of the syntheses and their limitations, structures and reactions of chalcogenocarboxylic acid derivatives, by emphasizing the developments in organic and inorganic chalcogen chemistry over the last 5 to 20 years.
Cereals and millets
Genome Mapping and Molecular Breeding in Plants presents the current status of the elucidation and improvement of plant genomes of economic interest. The focus is on genetic and physical mapping, positioning, cloning, monitoring of desirable genes by molecular breeding and the most recent advances in genomics. The series comprises seven volumes: Cereals and Millets; Oilseeds; Pulses, Sugar and Tuber Crops; Fruits and Nuts; Vegetables; Technical Crops; and Forest Trees.
Cell Surface Receptors : A Short Course on Theory and Methods
Cell Surface Receptors: A Short Course on Theory and Methods, 3rd Edition, links theoretical insights into drug-receptor interactions described in mathematical models with the experimental strategies to characterize the biological receptor of interest.
Cell Motility
Cell motility is a fascinating example of cell behavior which is fundamentally important to a number of biological and pathological processes. It is based on a complex self-organized mechano-chemical machine consisting of cytoskeletal filaments and molecular motors. In general, the cytoskeleton is responsible for the movement of the entire cell and for movements within the cell. The main challenge in the field of cell motility is to develop a complete physical description on how and why cells move. For this purpose new ways of modeling the properties of biological cells have to be found. This long term goal can only be achieved if new experimental techniques are developed to extract physical information from these living systems and if theoretical models are found which bridge the gap between molecular and mesoscopic length scales. Cell Motility gives an authoritative overview of the fundamental biological facts, theoretical models, and current experimental developments in this fascinating area.
Catalytic role of amino acids in organic reactions
Asymmetric organometallic and organocatalytic processes have attracted great interest. Asymmetric synthesis using both natural and unnatural amino acids has been tremendously important from synthetic as well as industrial viewpoints, and numerous new methodologies have been developed in the last decades. Herein we provide an overview of old and very recent (since 1900 till now) advances and applications in the area of heterogeneous catalysis, homogeneous catalysis, electrocatalysis, photocatalysis, organocatalysis, thermal catalysis using amino acids [proline, glycine, alanine, valine, serine, threonine, cysteine, methionine, asparagine, glutamine, lysine, arginine, histidine, aspartate, glutamate, phenylalanine, and tryptophan], (supported or unsupported), an amino acid containing materials or amino acids derivatives as an essential component of catalysts, this book highlights the most important and recent developments to immobilize or support amino acids on various support materials. This book is suitable as supplementary reading for courses targeting the design, synthesis, and application of chiral catalysts, asymmetric catalysis, and sustainable production.
Carbon-based nanocarriers for drug delivery
Carbon-Based Nanocarriers for Drug Delivery enlists the latitudes and advancements in the synthesis processes, functionalization, and applications of carbon-based nanomaterials (CBNs) in targeted drug delivery systems (DDSs). It covers the applicability and suitability of CBNs as nanocarriers for efficient drug delivery application via elucidating the recent advancements in CBNs, their functionalized and innovative derivatives, and the relevant case studies. The book explores the necessity, efficacy, toxicological aspects, and challenges for the application of CBN in targeted DDSs.
Carbon monoxide in drug discovery, basics, pharmacology, and therapeutic potential
Carbon monoxide, one of the smallest organic natural molecules, is widely known for its toxicity. Formation of CO via incomplete combustion is a major contributing factor to accidental or intentional CO poisoning, leading to severe health consequences or death. In addition, CO is a by-product of tobacco smoking, and has been associated with some of the harmful effects of smoking. However, less known and probably far more important is the recognition of the essential physiological roles of CO as a signaling molecule in mammals. Against over more than a century of negative connotation, the last few decades have proven that CO possesses a multitude of physiological roles and therapeutic functions including regulation of the immune response, cellular proliferation, and control of cell survival. This concept is supported by the discovery that CO is produced by all cells and more so under conditions of stress. This book comprehensively summarizes key aspects of CO's endogenous roles, therapeutic functions, and challenges that we face in its development as a therapeutic agent. We hope this preface will provide a thread for reading this book and a birds-eye view of the landscape for understanding this field, and more importantly lay out the challenges ahead in understanding the detailed mechanisms of action of CO and in its development as a therapeutic agent.
Carbohydrate-protein interactions : Methods and protocols
Provides new and updated tools for studying protein-carbohydrate interactions ranging from traditional biochemical methods to state-of-the-art techniques. This book focuses on four different research themes detailing methods for screening and quantifying CAZyme activity, investigating the interactions between proteins, carbohydrate ligands, methods for the visualization of carbohydrates, protein-carbohydrate complexes, structural and “omic” approaches for studying systems of CAZymes.
