الصفحة 168
الصفحة 168
Gene Therapy of Autoimmune Disease
Gene Therapy of Autoimmune Diseases comprehensively reviews research in gene therapy for autoimmune diseases with viral or non-viral vectors. Gene therapy offers the possibility of long-term, continuous delivery of a wide variety of immunosuppressive, anti-inflammatory, or tolerance-inducing agents. Moreover, highly specific genetically modified cells can be produced. This book discusses the most promising avenues in this exciting new field.
Gene Therapy for Cancer
The possibility of treating cancer, a disease defined by genetic defects, by introducing genes targeting these very alterations has led to an immense interest in gene therapy for cancer. Although incremental successes have been realized, enthusiasm for gene therapy has declined due to an increasing number of obstacles. These obstacles include vector systems that do not reach systemic metastases, therapeutic genes with redundant mec- nisms allowing for cellular resistance, and toxicities in clinical trials leading to premature closure of these studies. Different tactics to overcome or circumvent these obstacles have catalyzed the development of a wide range of gene therapy approaches. Thus far, almost two-thirds of gene therapy trials have focused on cancer. This reflects the concept that gene therapy approaches for the treatment of cancer do not necessarily require long-term expression of the gene as is necessary for the treatment of primary genetic defects like hemophilia or juvenile diabetes.
Gene Therapy and Gene Delivery Systems
Advances in Biochemical Engineering/Biotechnology reviews actual trends in modern biotechnology. Its aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required for chemistry, biochemistry, micro-biology, genetics, chemical engineering and computer science
Gene Expression Programming : Mathematical Modeling by an Artificial Intelligence
This monograph provides all the implementation details of GEP so that anyone with elementary programming skills will be able to implement it themselves. The book also includes a self-contained introduction to this new exciting field of computational intelligence, including several new algorithms for decision tree induction, data mining, classifier systems, function finding, polynomial induction, times series prediction, evolution of linking functions, automatically defined functions, parameter optimization, logic synthesis, combinatorial optimization, and complete neural network induction. The book also discusses some important and controversial evolutionary topics that might be refreshing to both evolutionary computer scientists and biologists.
Gene Expression and Regulation
This book offers a comprehensive look into the science of gene expression and regulation. Focusing on topics such as actions of nuclear receptors, RNA processing, and DNA methylation and imprinting, Gene Expression and Regulation is edited by a leading biologist and includes contributions by experts in the field. Presented in the following five sections, this book covers a full spectrum of topics: The History; The Machinery; The Regulators; The Genome; and Special Topics. The Machinery section covers the transcriptional apparatus and general transcription factors. The Regulators section examines selected gene-specific transcription factors important to regulating gene expression. The Genome section covers issues relevant to the behavior of the genome in relation to gene regulation. The Special Topics section discusses several selected topics ranging from bacterial and plant gene expression to DNA topology and interference RNA. The book’s focus is on scientific concepts and issues, rather than specific organisms or experimental approaches.
Gene drives at tipping points : Precautionary technology assessment and governance of new approaches to genetically modify animal and plant populations
This book reports on a pilot project aiming at collecting information on the socio-ecological risks that could arise in the event of an uncontrolled spread of genetically engineered organisms into the environment. The researchers will, for instance, be taking a closer look at genetically engineered oilseed rape, genetically engineered olive flies as well as plants and animals with so-called gene drives. The book mainly adresses researchers.
Genders in the Life Course : Demographic Issues
Treats the topic of gender and demographic behaviour during the life course in a comprehensive fashion. It covers a lot of ground, from the age at first intercourse over union formation and dissolution, fertility, migration, ageing, to excess male mortality, comparing genders behaviour and its determinants. It reports new findings of empirical research, mostly based on data from a number of European countries, making a good use of the Family and Fertility surveys and other international data base.
Gender, Health and Ageing : European Perspectives on Life Course, Health Issues and Social Challenges
The objective of this book is to provide an overview of gender, health and ageing. Important theoretical concepts, such as life course and "Lebenslagen" in old age, or differences in men's health, are introduced. It is increasingly important to build a European basis of knowledge, to conduct discussions on European research findings, and to develop European research frameworks. In this volume, central theoretical debates on gender impacts on life course and old-age health, and vital issues of health research in the context of gender and old age are introduced. Specific aspects, such as the impact of gender and age on cardiovascular health, elder abuse and mental health, or care between gender relations, gender roles and gender constructs, are pointed out.
Gender Innovation and Migration in Switzerland
This book analyses migration and its relation to socio-political transformation in Switzerland. It addresses how migration has made new forms of life possible and shows how this process generated gender innovation in different fields: the changing division of work, the establishment of a nursery infrastructure, access to higher education for women, and the struggle for female suffrage. Seeing society through the lens of migration alters the perspective from which our past and thus our present is told—and our future imagined.
Gender Equality Programmers in Higher Education : International Perspectives
For the last twenty years gender equality has been on the agenda of national higher education policies both within Europe and beyond it.the authors of this book analyse under which circumstances equality programmes are successful. In order to develop a deeper understanding of the mechanisms of and barriers to gender equality in higher education this book presents comparative studies and research focusing on the development of gender equality policies in different countries, as well as studies on the conditions for implementing policies, changes in strategies and the evaluation of gender equality programmes.
Gender Differences in Computer and Information Literacy : An In-depth Analysis of Data from ICILS
When computer technology was first introduced in schools, there was a prevailing belief that information and communication technologies were ‘boys’ toys’; boys were assumed to have more positive attitudes toward using computer technologies. As computer technologies have become more established throughout societies, gender gaps in students’ computer and information literacy appear to be closing, although studies into gender differences remain sparse.
Gender Designs IT : Construction and Deconstruction of Information Society Technology
The book not only offers a gender analysis of information society technologies, it also shows practical examples of how IT can be different. A gender perspective on IT design can serve as an eye-opener for what tends to be overlooked and left out. It yields innovative ideas and high quality software systems that may empower a large diversity of users for an active participation in our information society.
Gender and migration : IMISCOE short reader
This short reader offers a critical review of the debates on the transformation of migration and gendered mobilities primarily in Europe, though also engaging in wider theoretical insights. Building on empirical case studies and grounded in an analytical framework that incorporates both men and women, masculinities, sexualities and wider intersectional insights, this reader provides an accessible overview of conceptual developments and methodological shifts and their implications for a gendered understanding of migration in the past 30 years. It explores different and emerging approaches in major areas, such as: gendered labour markets across diverse sectors beyond domestic and care work to include skilled sectors of social reproduction; the significance of families in migration and transnational families.
GDPR and biobanking : Individual rights, Public interest and research regulation across Europe
This book focuses on the discrepancies in biobank research regulations that are among the most significant hurdles to effective research collaboration.
Gathering Hopewell : Society, Ritual and Ritual Interaction
In this book, twenty-one researchers in interwoven efforts immerse themselves and the reader in this vibrant archaeological record in order to richly reconstruct the faces, actions, and motivations Hopewellian people in their social and ritual life. Using a personalized and locally contextualized approach, the authors explore Hopewellian leadership, systems of social ranking and prestige, animal-totemic clan organization, kinship structures, sodalities, gender, community organizations, strategies of intercommunity alliance, and interregional travels for power questing, pilgrimage, healing, tutelage, and acquiring rituals.
Gastrointestinal Tract Sonography in Fetus and in Children
Sonography of the gastrointestinal tract in fetuses, neonates and children entails no known biological risk, permits serial scanning and can provide information unobtainable with any other imaging modality. In experienced hands it can be used as the initial imaging technique in a number of gastrointestinal diseases and conditions. This book provides a comprehensive account of the current state of the art regarding sonography in this context.
Gastrointestinal malignancies
Details the advances in drug discovery and delivery and the present need for emerging technologies. Throughout the text new micro and nanofabrication techniques are described, including methods such as electrohydrodynamic processes, additive manufacturing, and microfluidics, which have the potential to produce drug delivery systems that were not possible a few years ago. This book is of great use to both entry-level and experienced researchers in the field of emerging technologies for the manufacturing of drug delivery devices.
Gastrointestinal Cancer
Gastrointestinal cancer includes cancer of the digestive system - the esophagus, colon, rectum, anus, liver, pancreas, and other digestive organs. Taken as a whole, there are an estimated 250,600 new cases in the US. Colon and rectum cancer is the third leading cause of cancer and cancer deaths in the US. Gastrointestinal Cancer is the third volume in the M.D. Anderson Cancer Care series, featuring the current standard approach to GI cancer care from the experts at M.D. Anderson Cancer Center. Designed for the practicing oncologist, this clinical guidebook allows for quick, authoritative access to the latest and best multimodality therapies. Topics covered in this volume include AJCC staging of gastrointestinal malignancies, recent advances in histopathology of gastroinestinal cancers, imaging techniques and endoscopy in the management of GI malignancies, colorectal cancer, liver cancer, gastric cancer, esophageal cancer, anal cancer, and palliative therapy. Each of the 20 chapters ends with an up-to-date list of suggested readings, as well as "key practice points" highlighting the most principles and practices of each chapter for at-a-glance reference. More than 80 illustrations complement the text. This thorough, practical volume is the essential clinical guide for the oncologists, surgeons, and all physicians involved in the care of patients with GI cancer.
Gastroesophageal reflux disease : Principles of disease, diagnosis, and treatment
Gastroesophageal reflux disease (GERD) is one of the most common disorders with an increasing prevalence and incidence in the last two decades. This book presents clinically relevant information for gastroenterologists, internists, surgeons, residents and also nurses, who frequently care for GERD patients.
Gastroesophageal reflux disease : From pathophysiology to treatment
Offers a state-of-the-art description of the pathophysiology, diagnosis and treatment of gastroesophageal reflux disease (GERD). Although GERD is one of the most common gastrointestinal disorders, its diagnosis and management are often challenging. Expert physicians provide an evidence- and experience-based analysis in each chapter.
