Handbook of pharmaceutical wet granulation : Theory and practice in a quality by design paradigm
Handbook of Pharmaceutical Wet Granulation: Theory and Practice in a Quality by Design Paradigm offers a single and comprehensive reference dedicated to all aspects of pharmaceutical wet granulation, taking a holistic approach by combining introductory principles with practical solutions. Chapters are written by international experts across industry, academic and regulatory settings, and cover a wide spectrum of relevant and contemporary wet granulation topics, techniques and processes. The books' focus on process analytical technology, quality by design principles, granulation equipment, modeling, scale-up, control and real time release makes it a timely and valuable resource for all those involved in pharmaceutical wet granulation.
Handbook of Petroleum Processing
"This Handbook describes and discusses the features that make up the petroleum refining industry. It begins with a description of the crude oils and their nature. It continues with the saleable products from the refining processes, with a review of the modern day environmental impact. There is a complete overview of the processes that make up the refinery with a brief history of the processes. It also describes design technique, operation, and, in the case of catalytic units, the chemistry of the reaction routes. These discussions are supported by calculation procedures and examples, sufficient to enable good input to modern computer simulation packages. The Handbook also covers off-sites and utilities, as well as environmental and safety aspects relevant to the industry."
Handbook of nutrition and pregnancy
This book discusses relevant topics in the scientific community such as determining to what extent prenatal and perinatal environmental factors are linked to childhood and adult obesity and chronic diseases. This book also examines issues that are common to both the developed and the developing worlds and includes chapters that are specific to nutritional and reproductive factors seen mainly in developing countries. These chapters discuss contemporary issues that impact both the woman and the developing infant. Also covered in several chapters is a review of nutritional as well as physiological factors that either increase or decrease the potential for high risk pregnancies such as gestational diabetes mellitus, Type I and Type II diabetes mellitus, preeclampsia, anemia, and so forth.
Handbook of nutrition and ophthalmology
The Handbook of Nutrition in Ophthalmology is the first general text on nutrition and eye health created for physicians, nutritionists, and researchers. Dr. Richard D. Semba provides important links between the epidemic of obesity and implications it has for eye disease and blindness. The volume addresses three broad themes throughout. The first is that a healthy diet as a major lifelong habit will likely have an impact on reducing a substantial portion of visual impairment and blindness. The second is that a historical perspective is essential to understanding current challenges in ophthalmology, medicine, and public health. The third theme is that many nutrients play a role in oxidative stress and inflammation, and this theory has emerged as a major underlying hypothesis in the pathogenesis of eye diseases.
Handbook of nutraceuticals and natural products : Biological, medicinal, and nutritional properties and applications ; 2 Volume set
Describes the preparation techniques and functional uses of nutraceuticals and natural products with a focus on the technologies involved. The book includes coverage of the biological, medicinal, and nutritional properties and applications of functional foods, as well as the advanced technologies used in the extraction and functionalization of nano components and the nanomaterial and nanochemical aspects of the products.
Handbook of neurochemistry and molecular neurobiology : Sensory neurochemistry
This volume of the Handbook of Neurochemistry and Molecular Biology focuses on molecular events involved in synapse formation, synaptic plasticity and ongoing neural activity. The volume explores axonal growth cones, synapse development, and mechanisms of LTP and LTD, and calcium dynamics.
Handbook of neurochemistry and molecular neurobiology : Practical neurochemistry methods
The Handbook is intended to be a service to the neuroscience community, to help in finding available and useful information, to point out gaps in our knowledge, and to encourage continued studies. It represents the valuable contributions of the many authors of the chapters and the guidance of the editors and most important, it represents support for research in this discipline. Based on the rapid advances in the years since the second edition
Handbook of neurochemistry and molecular neurobiology : Neurotransmitter Systems
The brain is the organ that collects information from the environment, processes and stores the information, and generates behavior as and when needed. In essence, the brain makes us who we are. For this reason, understanding the biology of brain function is a great challenge and a major goal of modern science. The brain is one of the last great frontiers in science, and the unraveling of its mysteries is comparable in complexity to efforts in space exploration. A fundamental goal of neuroscience is to understand how neurons generate behavior and the pathophysiology of different mental and neurological diseases. This requires, among other things, information about where these neurons are located, how they are connected, and how they communicate with each other in various physiological and pathophysiological conditions. Our aim is to describe recent discoveries about the basic operations of the brain and to provide an introduction to the adaptations for specific types of information processing.
Handbook of neurochemistry and molecular neurobiology : Neuroimmunology
Neuroimmunology is one of the most rapidly developing branches of Neurobiology, and this volume contains chapters that focus on a huge range of topics including the relationship between neuroimmunology and the pathogenesis of different nervous diseases.
Handbook of neurochemistry and molecular neurobiology : Neural Protein Metabolism and Function
This volume discusses aspects of neural protein metabolism. Although this subject is clearly very important and has numerous functional aspects, it did not always get the attention it clearly deserves. Perhaps there are many explanations for researchers hesitating in the past to focus on protein metabolism.
Handbook of neurochemistry and molecular neurobiology : Neural Membranes and Transport
The first section of this volume deals with neural membranes and barriers. The second section covers ion pumps and ion transporters in neural membranes. The final section covers neural membranes and transport of neurotransmitters or other solutes.
Handbook of neurochemistry and molecular neurobiology : Development and Aging Changes in the Nervous System
In the animal nervous system, a very high metabolic turnover, fragile but steep ionic gradients, and morphological and structural constraints - dictated by the necessity for prompt neuronal transmission of electrical impulses and necessary plasticity - result in a highly fragile organ system. Here, we address a small sampling of major constituents of neural function at the cellular and molecular level that play important roles in development and aging, two endogenous processes that embody features of allostasis or the dynamic shifts in set points for specific homeostatic mechanisms associated with development and aging. These chapters stress the dynamic features of neuronal responses to internal (developmental) cues or the more harmful external events (injury and disease) in a modern perspective.
Handbook of neurochemistry and molecular neurobiology : Degenerative Diseases of the Nervous System
The Second Edition of the Handbook of Neurochemistry, which was published about 24 years ago, consisted of 10 volumes. In addition to metabolic processes, the 17 new volumes explore the functions of peptides, transport, immunology and other processes not well understood 24 years ago.
Handbook of neurochemistry and molecular neurobiology : Brain Energetics. Integration of Molecular and Cellular Processes
Focuses on aspects of energy metabolism that are unique to the brain. The goal of each chapter is to provide a fundamental overview of each area, to define the state-of-the-art in that area as it relates to brain, and, where appropriate, describe models that portray poorly understood and apparently contradictory data sets with the goal of helping focus attention to experimental resolution of controversial issues.
Handbook of neurochemistry and molecular neurobiology : Behavioral Neurochemistry, Neuroendocrinology and Molecular Neurobiology
The Handbook is intended to be a service to the neuroscience community, to help in finding available and useful information, to point out gaps in our knowledge, and to encourage continued studies. It represents the valuable contributions of the many authors of the chapters and the guidance of the editors and most important, it represents support for research in this discipline. Based on the rapid advances in the years since the second edition.
Handbook of neurochemistry and molecular neurobiology : Amino acids and peptides in the nervous system
It is our belief that this volume of the Handbook of Neurochemistry and Molecular Neurobiology provides an excellent review of the tremendous advances of the past decades in the neurochemical and molecular biological aspects of cerebral ischemia. It is hoped that these advances will provide an impetus for basic scientists and clinicians to further their translational research and to promote the insights for development of therapeutic interventions for stroke.
Handbook of neurochemistry and molecular neurobiology : Acute Ischemic injury and repair in the nervous system
It is our belief that this volume of the Handbook of Neurochemistry and Molecular Neurobiology provides an excellent review of the tremendous advances of the past decades in the neurochemical and molecular biological aspects of cerebral ischemia. It is hoped that these advances will provide an impetus for basic scientists and clinicians to further their translational research and to promote the insights for development of therapeutic interventions for stroke.
Handbook of modern sensors. physics, designs, and applications
Presents a comprehensive and up-to-date account of the theory (physical principles), design, and practical implementations of various sensors for scientific, industrial, and consumer applications. This latest edition focuses on the sensing technologies driven by the expanding use of sensors in mobile devices. These new miniature sensors will be described, with an emphasis on smart sensors which have embedded processing systems. The chapter on chemical sensors has also been expanded to present the latest developments.
Handbook of microscopy for nanotechnology
Handbook of Microscopy for Nanotechnology aims to provide an overview of the basics and applications of various microscopy techniques for nanotechnology. This handbook highlights various key microcopic techniques and their applications in this fast-growing field. Topics to be covered include the following: scanning near field optical microscopy, confocal optical microscopy, atomic force microscopy, magnetic force microscopy, scanning turning microscopy, high-resolution scanning electron microscopy, orientational imaging microscopy, high-resolution transmission electron microscopy, scanning transmission electron microscopy, environmental transmission electron microscopy, quantitative electron diffraction, Lorentz microscopy, electron holography, 3-D transmission electron microscopy, high-spatial resolution quantitative microanalysis, electron-energy-loss spectroscopy and spectral imaging, focused ion beam, secondary ion microscopy, and field ion microscopy.
Handbook of In Vivo Chemistry in Mice : From Lab to Living System
The Handbook of In Vivo Chemistry in Mice: From Lab to Living System introduces readers to general information about live animal experiments and detection methods commonly used for these animal models. It focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release.



















