الصفحة 16
الصفحة 16
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Mammalian Subventricular Zones : Their Roles in Brain Development, Cell Replacement, and Disease

This text provides a comprehensive summary of research and findings that have lead to the current understanding of the subventricular zones. It provides an overview of the roles of subventricular zones in normal development and in disease and a foundation from which current and future studies can be evaluated.

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Make Life Visible

This book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completely impossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy.

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Magnetic Resonance of Myelination and Myelin Disorders

The book has been extensively revised and expanded to do justice to the rapid advances in MR technology, molecular biochemistry, and genetics and the discovery of new disease entities with prominent white matter involvement. Forty chapters have been added, and the number of illustrations has risen considerably. The ability to confirm the presence of genetic alterations in a number of disorders allows more advantageous presentation of the phenotypic variation as expressed in differ.

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Machine Learning Refined : Foundations, Algorithms, and Applications

Provides students with the fundamental knowledge and practical tools needed to conduct research and build data-driven products. The authors prioritize geometric intuition and algorithmic thinking, and include detail on all the essential mathematical prerequisites, to offer a fresh and accessible way to learn. Practical applications are emphasized, with examples from disciplines including computer vision, natural language processing, economics, neuroscience, recommender systems, physics, and biology.

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Machine learning refined : Foundations, algorithms, and applications

Providing a unique approach to machine learning, this text contains fresh and intuitive, yet rigorous, descriptions of all fundamental concepts necessary to conduct research, build products, tinker, and play. By prioritizing geometric intuition, algorithmic thinking, and practical real world applications in disciplines including computer vision, natural language processing, economics, neuroscience, recommender systems, physics, and biology, this text provides readers with both a lucid understanding of foundational material as well as the practical tools needed to solve real-world problems. With in-depth Python and MATLAB/OCTAVE-based computational exercises and a complete treatment of cutting edge numerical optimization techniques, this is an essential resource for students and an ideal reference for researchers and practitioners working in machine learning, computer science, electrical engineering, signal processing, and numerical optimization

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Machine learning for neurodegenerative disorders : advancements and applications

Explores the application of machine learning to the understanding, early diagnosis, and management of neurodegenerative disorders. With a specific focus on its role in ongoing clinical trials, the book covers essential topics such as data collection, pre-processing, feature extraction, model development, and validation techniques. It delves into the applications of neuroimaging techniques like magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) in the diagnosis and understanding of neurodegenerative disorders. Additionally, the book examines various machine-learning algorithms employed for biomarker discovery in neurodegenerative disorders. It highlights the role of neuroinformatics and big data analysis in advancing the understanding and management of neurodegenerative disorders. Furthermore, the book reviews future prospects and presents the ethical considerations and regulatory challenges associated with implementing machine learning approaches in the diagnosis, treatment, and prevention of neurodegenerative disorders.

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Machine learning for brain disorders

Organized into five parts. Part One presents the fundamentals of ML. Part Two looks at the main types of data used to characterize brain disorders, including clinical assessments, neuroimaging, electro- and magnetoencephalography, genetics and omics data, electronic health records, mobile devices, connected objects and sensors. Part Three covers the core methodologies of ML in brain disorders and the latest techniques used to study them. Part Four is dedicated to validation and datasets, and Part Five discusses applications of ML to various neurological and psychiatric disorders.

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Logos of phenomenology and phenomenology of the logos ; Book Two : The Human Condition in-the-Unity-of-Everything-there-is-alive Individuation, Self, Person, Self-determination, Freedom, Necessity

The Human Condition-in-the-unity-of-everything-there-is-alive, under whose aegis the present selection of essays falls, offers the urgently needed new approach to reinvestigating humanness. While recent advances in the neurosciences, genetics and bio-engineering challenge the traditional abstract conception of "human nature", indicating its transformability, thus putting in question the main tenets of traditional philosophical anthropology, in the new perspective of the Human Creative Condition the human individual is seen in its emergence and unfolding within the dynamic networks of the logos of life, and within the evolution of living types.

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Liver Radioembolization with Y90 Microspheres

Provides an in-depth account of all aspects of radioembolization, a relatively novel technique based on the efficacy of radiotherapy for the treatment of liver tumors.

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Liver and Pancreatic Diseases Management

New therapeutical approaches, advances in oncology and in diagnostic imaging, which reduce the need for invasive techniques and reach an improvement in survival and quality of life in cancer, are considered in this book. Modern literature has been reviewed with special reference to articles of general interest. In the clinical management of patients with liver, bile duct and pancreas diseases, it is important to assess the degree of disturbance and to diagnose the causative insult, and therefore clinical and laboratory methods of assessing each of these pathologies are of high interest. This version is an up-to-date account of diseases of the liver, biliary tract and pancreas, including transplantation, which we trust will be of value for surgeons, physicians and pathologists and also a reference book for medical students.

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Lippincott illustrated reviews : Pharmacology

Presents up-to-date drug information in an accessible format ideal for a fast, effective refresher. Part of the popular Lippincott® Illustrated Reviews series, this concise resource features clear, effective writing and hundreds of illustrations that break down complex information for rapid review. Sequential images present mechanisms of action and focus on showing rather than telling students how drugs work, and review questions with answers deliver powerful, practical exam preparation. Updated drug information reflects the most current, clinically relevant pharmacology material. Approachable outline format distills complex information for easier review. High-quality illustrations reinforce understanding in vibrant detail. Enhanced review questions with answers test students' understanding and identify areas for further study.

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Lifestyle psychiatry through the lens of behavioral medicine

Lifestyle medicine is a practice which adopts evidence-based lifestyle interventions as a primary modality to prevent, treat, and reverse chronic diseases. The six main pillars of this specialty include physical activity, nutrition, stress resilience, cessation or risk reduction of substance use, quality sleep, and connectivity. Lifestyle psychiatry is a rapidly emerging area within healthcare informed by rigorous research within the social and biological sciences, public health, and medicine. A volume in the Lifestyle Medicine series, this book uses a comprehensive biopsychosocial approach to prevent and treat psychiatric disorders and promote mental and physical well-being through evidence-based lifestyle interventions.

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Lifestyle medicine

Contains extensive sections on the treatment and prevention of coronary heart disease,stroke, cancer, diabetes, obesity, substance abuse, dementia, and many other clinical conditions. Key lifestyle modalities such as physical activity, nutrition, weight management, sleep, stress reduction, and positive connections with other humans are supported by detailed discussion and state-of-the-art evidence. The expanded section on behavioral medicine provides an important framework for these discussions. Every chapter has been completely revised and many new topics added, such as lifestyle medicine for nursing, psychiatry, and preventive neurology.

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Les fonctions sphinctériennes = Sphincter functions

This book on Sphincter functions provides an update on a very topical subject, urinary and anal incontinence. Divided into three parts, it first deals with fundamental aspects, whether anatomical, physiological or clinical. The explorations of the various urinary and anorectal functions are described with electrophysiological, manometric, urodynamic tests as well as imaging. The second part is devoted to the pathology with all the dysfunctions that we encounter in daily practice. Urinary and anal incontinence, dysuria and retention, neurological sphincter disorders, dysfunctions in pregnant women and children are discussed. The last part takes stock of treatments, whether pharmacological, rehabilitative or surgical. This work, which contains a considerable amount of information, will undoubtedly be of interest to many medical specialists (physicians in physical medicine and rehabilitation, neurologists, gastroenterologists, gynecologists, general practitioners, pediatricians), surgeons (urologists, gynecological surgeons, surgeons). digestive) whether they are in training or already involved in the management of perineal disability. Other health professionals will find reference material there (nurses, physiotherapists, midwives).

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Les douleurs abdominales en questions : Rôle physiopathologique de la sensibilité viscérale = Abdominal pain in question : The pathophysiological role of visceral sensitivity

The gut-brain axis refers to the network of nerve pathways that connect the myenteric plexus, the veritable "gut brain," to the central nervous system. Nearly 80% of these neurons are sensory neurons, and the afferent pathways that transmit information from the digestive tract to the central nervous system play a crucial role in the physiological regulation of digestive functions, as well as in certain pathological conditions. A large majority of these sensations remain unconscious and give rise to reflex responses. Only those requiring a conscious response reach the level of awareness in a normal state (hunger, thirst, the urge to defecate). In pathological situations, the same is true for painful sensations of digestive origin. Functional bowel disorders are a frequent reason for consultation. Their pathophysiology is now based on a model integrating the various etiological factors around the brain-gut axis. These patients frequently present with visceral hypersensitivity, which manifests as an increased perception of digestive sensations, notably the onset of pain in response to stimuli that are not painful in normal subjects. Recognizing the role of visceral hypersensitivity has made it possible to explain the mechanism of action of medications used to treat functional bowel disorders and paves the way for the development of new molecules acting on digestive afferents. In this book, we will describe the anatomical and physiological basis for understanding the concept of visceral sensitivity and the role of digestive afferents in the pathophysiology of acute and chronic abdominal pain, particularly irritable bowel syndrome.

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Leptin

The discovery of leptin little more than a decade ago, as a hormone produced in white adipose tissue with an important role in satiety and energy expenditure, was a seminal event in our understanding of adiposity. This initial advance in the new endocrinology of obesity was soon followed by the realization that leptin was not only produced in adipose tissue, but in many different tissues of the body, and that receptors were similarly distributed. Additionally, the early recognition of infertility that was associated with leptin deficiency prompted research that identified roles for the polypeptide in virtually every area of reproductive biology.

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Lectures in Supercomputational Neurosciences : Dynamics in Complex Brain Networks

The present volume is an introduction, largely from the physicists' perspective, to the subject matter with in-depth contributions by system neuroscientists. A conceptual model for complex networks of neurons is introduced that incorporates many important features of the real brain, such as various types of neurons, various brain areas, inhibitory and excitatory coupling and the plasticity of the network. The computational implementation on supercomputers, which is introduced and discussed in detail in this book, will enable the readers to modify and adapt the algortihm for their own research.

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Lecture Notes on General Medicine for Dental Practice : A System based Approach with Dental Management Considerations

Offers a system based approach covering a broad range of topics in general medicine for dental practice. The book includes chapters on history taking and patient interview, general physical examination, system specific examination, common health related complaints, systemic infections, and diseases of the gastrointestinal, cardiovascular, respiratory, neurological, immunological, renal, endocrinal, dermatological and musculoskeletal systems. Nutritional disorders, psychiatric disorders, the female patient with menstrual, menopause and pregnancy related disorders, dental management of patients taking medications for systemic conditions and medical emergencies in dental practice have also been discussed in some detail.

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Le forme spastiche della paralisi cerebrale infantile : Guida all'esplorazione delle funzioni adattive = Spastic forms of cerebral palsy : A guide to exploring adaptive functions

Offers "travel notes" on the topics covered, to spark reflection and comparisons with the readers' experience. The authors address the topics from a pathophysiological perspective that guides their interpretation of the nature of the defect (functional diagnosis), the problems related to prognosis (as a natural history hypothesis), and rehabilitation (as a modification of the architecture of the function in an adaptive sense).The text is accompanied by an extensive glossary of terms used and a DVD with clinical cases, organized according to the authors' classification. This material also highlights the volume's great educational value, both for those already working in this field (physicians, child neuropsychiatrists and physiatrists, rehabilitation therapists) and for students completing their first and second level degrees in rehabilitation and attending postgraduate schools.

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Le complicazioni neurologiche in oncologia = Neurological complications in oncology

This volume, both necessary and new in the panorama of Italian medical literature, acknowledges this and presents an updated and complete review of the pathologies of the central and peripheral nervous system associated with tumors and their treatment. The purpose of the volume is to present an integrated approach between specialists that must see the neurologist and the oncologist in dialogue, and able to develop a new super-specialized clinical capacity in neuro-oncology. Many experts have contributed to its preparation by sharing knowledge on topics ranging from metastatic complications, to those of surgical cancer therapy, radio- and chemo-therapy, paraneoplastic syndromes, pain therapy, delirium and the affective alterations associated with the disease. The book is aimed in particular at neurologists, oncologists, palliative care practitioners and surgeons, but it is certainly useful for general practitioners and all operators who are daily involved in the demanding work of taking care of cancer patients.

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