الصفحة 16
الصفحة 16
Insights into the pharmaceutical and clinical applications of nanoparticles in cancer therapy
Healthcare has long been on a quest for a ‘magic bullet’ to cure the dreaded disease cancer. As this book shows, nanoparticles perfectly fit the bill with their promising characteristics. Meticulously engineered nanostructures, with a useful drug or molecule, target a specific cancer in unique ways. However, as with many targeted systems, the effectiveness of the system needs to be weighed against the adverse effects. The toxicity of nanoparticles has been a worldwide concern, and evidence-based medicine analyses nanostructures for proof of safety and their efficacy in killing cancer cells. This book gives a fresh perspective on a wealth of diverse nanotechnological advances for various cancers.
Insects and Ecosystem Function
In the past two decades, an increasing number of ecologists have started to investigate the importance of biodiversity for ecological processes such as energy flow and nutrient cycling, often referred to as 'ecosystem functioning'. Insects are a dominant component of biodiversity in terrestrial ecosystems and play a key role in mediating the relationship between plants and ecosystem processes. This volume is the first to summarize their effects on ecosystem functioning, focusing mainly, but not exclusively, on herbivorous insects. Renowned authors with extensive experience in the field of plant-insect interactions, contribute to the volume using examples from their own work. In addition to providing concise reviews of the field, this volume discusses in detail the advantages and disadvantages of various techniques of manipulating insect herbivory. Thus, the text provides both a theoretical basis as well as practical advice for future manipulative studies of biodiversity-ecosystem functioning.
Innovative Models for Sustainable Development in Emerging African Countries
Explores key issues and presents recent case studies in areas of importance for the transition to a circular model of development in emerging African countries that will minimize resource consumption and waste production.
Innovative Medicine : Basic Research and Development
Devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”.
Innovations in preventive dentistry
Preventive dentistry is a constantly changing and developing field: As new research emerges, some practices that had once been revolutionary are abandoned, while others continue to withstand the test of time. This book discusses new developments and innovations in preventive dentistry, from primary prevention to secondary prevention by inactivating initial lesions, and on to tertiary prevention to avoid subsequent progression and complications of manifest oral disease. The book relies on a solid evidence base and instructs readers how this can be translated into clinical dental practice—what changes should be made to how we practice and why they should be made. Topics include caries and periodontal disease, orthodontic problems, diagnostic approaches, diet and oral health, oral hygiene, oral disease patterns, caries treatment, fluoride guidelines, risk management, sealants, and probiotics.
Innovations in healthcare and outcome measurement : New approaches for a healthy lifestyle
Aims to bring up-to-date new ideas, opinions, development, and critical issues in healthcare and personalized medicine. We are interested in relevant articles covering a broad range of topics, such as: Advances in medical devices, Digitalization and data-driven technologies, AI and algorithm-based drug development (molecule building, enhancement, clinical trials), Diagnostic imaging, Personalized medicine, Nutrition, Oral health care, Healthcare management in certain diseases and population groups, Regulatory developments, Data management, Digital healthcare.
Innovation in Life Cycle Engineering and Sustainable Development
Business models, which aims at determining how efficient can be a life cycle strategy from different point of view (customer, policy, environment, economics,…). End of life strategies, presenting recent approaches and technological solutions for end-of life treatments. Product development for sustainability, which aims at showing how designers integrate environmental conside- tions to improve their solutions. Product life cycle management, dealing with methods and tools to support life cycle considerations.
Injuries in Athletics : Causes and Consequences
This book focuses on both applied and conceptual issues regarding the classification of injuries, common coaches’ errors leading to injury, coaches and athletes’ viewpoints on injury, the development of psychological trauma in athletes, traumatic brain injuries and basic principles of rehabilitation. It is organized into five parts: - Foundations of injuries in athletics - Coaches and Athletes’ perspectives of injury - Psychological traumas in athletes - Concussion in athletics - Injury rehabilitation This reference book accumulates the latest developments in the science of athletes' training, from "injury-free" perspectives along with psychological analyses, evaluation, and management of sport-related injuries. It is an ideal resource for coaches, clinical practitioners, researchers and students interested in kinesiology, sport psychology and athletic training.
Injectable Fillers in Aesthetic Medicine
Fillers in Aesthetic Medicine is an excellent and comprehensive overview on the clinical use of fillers in aesthetic medicine. It is designed to assist dermatologists as well as plastic surgeons in the aesthetic medical treatment of their patients.
Inhibitors of protein kinases and protein phosphates
The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases.
Information Technology Solutions for Healthcare
This book presents the current and future trends in the transformation of healthcare services in the Information Society Era and is of great relevance to informatics professions, clinical managers and all clinicians using these new technologies as part of their practice.
Informatics for the Clinical Laboratory : A Practical Guide
This series is directed to healthcare professionals who are leading the tra- formation of health care by using information and knowledge. Launched in 1988 as Computers in Health Care, the series offers a broad range of titles: some addressed to specific professions such as nursing, medicine, and health administration; others to special areas of practice such as trauma and radi- ogy. Still other books in the series focus on interdisciplinary issues, such as the computer-based patient record, electronic health records, and networked healthcare systems. Renamed Health Informatics in 1998 to reflect the rapid evolution in the discipline now known as health informatics, the series will continue to add titles that contribute to the evolution of the field. In the series, eminent - perts, serving as editors or authors, offer their accounts of innovations in health informatics. Increasingly, these accounts go beyond hardware and so- ware to address the role of information in influencing the transformation of healthcare delivery systems around the world. The series also increasingly focuses on “peopleware” and the organizational, behavioral, and societal changes that accompany the diffusion of information technology in health services environments.
Inflammatory Bowel Disease and Familial Adenomatous Polyposis : Clinical Management and Patients' Quality of Life
Inflammatory bowel disease (IBD) and familial adenomatous polyposis (FAP) are complex diseases, which are subject to numerous medical researches. IBD and FAP represent a challenge for a multidisciplinary medical approach where different personnel play major roles in different stages of the patient’s treatment.
Inflammatory Bowel Disease : From Bench to Bedside
Inflammatory Bowel Disease: From Bench to Bedside is a detailed and comprehensive story of the local and systemic pathophysiology of intestinal inflammation including management strategies. Research advances and current concepts of etiopathogenesis in the context of what is already known of the clinicopathologic features of these disorders are explored. This volume blends recent advances in the basic and clinical sciences as they relate to inflammatory bowel disease and emphasizes the effectiveness of a team approach of basic scientists and clinician investigators in this field.
Inflammatory Arthritis in Clinical Practice
Inflammatory Arthritis in Clinical Practice is intended primarily as a concise practical handbook for general practitioners, rheumatology doctors in training and those in related specialties like orthopaedics. It will also be of interest to specialist nurses and allied health professionals working in the field. It covers all aspects of the diagnosis and management of rheumatoid arthritis and spondyloarthropathies
Inference for change point and post change means after a CUSUM test
This monograph is the first to systematically study the bias of estimators and construction of corrected confidence intervals for change-point and post-change parameters after a change is detected by using a CUSUM procedure. Researchers in change-point problems and sequential analysis, time series and dynamic systems, and statistical quality control will find that the methods and techniques are mostly new and can be extended to more general dynamic models where the structural and distributional parameters are monitored. Practitioners, who are interested in applications to quality control, dynamic systems, financial markets, clinical trials and other areas, will benefit from case studies based on data sets from river flow, accident interval, stock prices, and global warming. Readers with an elementary probability and statistics background and some knowledge of CUSUM procedures will be able to understand most results as the material is relatively self-contained.The exponential family distribution is used as the basic model that includes changes in mean, variance, and hazard rate as special cases. There are fundamental differences between the sequential sampling plan and fixed sample size. Although the results are given under the CUSUM procedure, the methods and techniques discussed provide new approaches to deal with inference problems after sequential change-point detection, and they also contribute to the theoretical aspects of sequential analysis. Many results are of independent interests and can be used to study random walk related stochastic models.
Infection Control in the Intensive Care Unit
Infection Control in the Intensive Care Unit has been entirely rewritten in this second edition. All statements are justified by the best available evidence, avoiding unsubstantiated expert opinion. The book contains a new section dedicated to the microbiology of the critically ill, specifically, how to process and interpret surveillance cultures to distinguish the ‘normal’ from the ‘abnormal’ carrier state. There are five totally new chapters dealing with evidence-based infection control molecular techniques for outbreak analysis; clinical virology in neonatal, paediatric and adult intensive care; the six basic principles of the therapy of an infection; and the role of the pharmacist in infection control. Attention is given to special topics such as nutrition, gut mucosal protection and the control of antimicrobial resistance. The addition of enteral to parenteral antimicrobials contributes to the control of multi-resistant micro-organisms. This completely revised second edition is a ‘must have’ for anyone requiring in depth knowledge in the ever expanding field of infection control.
Infection and Local Treatment in Orthopedic Surgery
The management of orthopedic infection is an area of growing importance in orthopedic surgery. This text provides a complete overview from basic research to clinical application and future perspectives in the treatment of orthopedic infection emphasising the role of local therapy. The unprecedented collection of experiences of the major experts in the field supplies the reader with long-awaited guidelines for treatment. Covering the various approaches to the treatment of orthopedic infections.
Indian Agriculture Towards 2030 : Pathways for Enhancing Farmers’ Income, Nutritional Security and Sustainable Food and Farm Systems
The book comprises of ten contributions. Apart from the overview chapter on transformational change and the concluding chapter on pathways for 2030, there are eight thematic chapters on topics such as transforming Indian agriculture, dietary diversity for nutritive and safe food; climate crisis and risk management; water in agriculture; pests, pandemics, preparedness and biosecurity natural farming; agroecology and biodiverse futures; science, technology and innovation in agriculture; and structural reforms and governance.
Increasing climate variability and change : Reducing the vulnerability of agriculture and forestry
One of the major challenges facing humankind is to provide an equitable standard of living for this and future generations: adequate food, water and energy, safe shelter and a healthy environment. Human-induced climate change, and increasing climate variability, as well as other global environmental issues such as land degradation and loss of biological diversity, threaten our ability to meet these basic human needs. It is undisputed that the last two decades have been the warmest this century, and likely to be the warmest for the last 1000 years, sea level is rising, rain and snowfall patterns are changing.
