الصفحة 158
الصفحة 158
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Golden gate cloning : Methods and protocols

Provides an overview of the latest protocols that cover the full range of in silico, in vitro, and in vivo approaches to help researchers plan, design, and perform Golden Gate cloning experiments. The chapters in this book cover topics such as Golden Gate cloning of standardized parts; modular DNA construct design for high-throughput Golden Gate Assembly; Golden Gate cloning of Synthetic CRISPR RNA spacer sequences; Golden Gate cloning in Actinobacteria; and YeastFab cloning of toxic genes and protein expression optimization in yeast.

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Goguen Categories : A Categorical Approach to L-fuzzy Relations

This book introduces several categorical formulations of an abstract theory of relations such as allegories, Dedekind categories and related structures. It is shown that neither theory is sufficiently rich to describe basic operations on fuzzy relations. The book then introduces Goguen categories and provides a comprehensive study of these structures including their representation theory, and the definability of norm-based operations.

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Glycoscience : Chemistry and Chemical Biology I-III

Glycostructures play a pivotal and crucial role in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Within recent years tools have been developed to promote the understanding of their highly complex functions and the associated chemistry and chemical biology, however, many facts still remain undiscovered.

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Glycopeptides and Glycoproteins : Synthesis, Structure, and Application

Their structure, biosynthesis, and mode of action are summarized in the fth chapter. The last chapter covers current methods for the determination of high-resolution structures of glycopeptides and glycoproteins mainly based onNMRspectroscopy, X-raycrystallography,and molecular modeling.This series presents critical reviews of the present position and future trends in modern chemical research Short and concise reports on chemistry.

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Glycobiology and Medicine ; Proceedings of the 7th Jenner Glycobiology and Medicine Symposium.

The potential for glycobiology to improve the practice of medicine has been well recognised, which is why biannual meetings concerning the association have been taking place for the last 14 years. The science of glycobiology has matured rapidly, and with it the far reaching clinical implications are becoming understood. The next decade is going to see this final frontier of science conquered. The impact this understanding of glycobiology will have upon our practice of medicine is going to be exciting. The 7th Jenner Glycobiology and Medicine Symposium was designed to reflect these advances. All the major clinical areas were involved, with contributions from pivotal players in science and medicine.

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Glycerophospholipids in brain : Phospholipases A2 in Neurological Disorders

This unique volume will be invaluable not only to those interested in biochemical properties of phospholipases A2, but also their involvement in neurological disorders. Students will benefit from it as a supplement for a range of neuroscience courses. Clinicians will find it invaluable as well for understanding molecular aspects of neurodegeneration in acute neural trauma (stroke) and neurodegenerative diseases (Alzheimer disease) that are mediated by phospholipases A2.

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Glutamate Receptors in Peripheral Tissue : Excitatory Transmission Outside the CNS

The book is divided into three sections— Part I is on general concepts and concentrates on the distribution and cell-specific localiza­ tion of glutamate receptors, their transporters, and the pharmacology in peripheral tissues and organs. Part II emphasizes the presence and implications of these receptors in specific target tissues, organs, and systems, including liver, lungs, endocrine tissues, bone, immune system, etc. Part III focuses on glutamate receptors in plants to illustrate their presence beyond the animal kingdom.

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Glucose Sensing

This volume incorporates authoritative analytical fluorescence-based glucose sensing reviews specialized enough to be attractive to professional researchers, yet also appealing to the wider audience of scientists in related disciplines of fluorescence. Glucose Sensing is an essential reference for any lab working in the analytical fluorescence glucose sensing field. All academics, bench scientists, and industry professionals wishing to take advantage of the latest and greatest in the continuously emerging field of glucose sensing, and diabetes care & management, will find this volume an invaluable resource.

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Globalization from the Bottom Up : A Blueprint for Modern Capitalism

This book argues that concentration of wealth is not sustainable. It offers an alternative model, a philosophy of "social capitalism" that is grounded in a bottom-up approach to wealth creation and presents a view of a more inclusive and sustainable future.

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Globalization and Urban Development

Most research on globalization has focused on macroeconomic and economy-wide consequences. This book explores an under-researched area, the impacts of globalization on cities and national urban hierarchies, especially but not solely in developing countries. Most of the globalization-urban research has concentrated on the "global cities" (e.g. New York, London, Paris, Tokyo) that influence what happens in the rest of the world. In contrast, this research looks at the cities at the receiving end of the forces of globalization. The general finding is that large cities, on balance, benefit from globalization, although in some cases at the expense of widening spatial inequities.

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Globalization and Sustainable Development : Environmental Agendas

A characteristic of the present global ecological situation is increasing instability or— put another way—a crisis in the civilization system, the global scale of which is expressed through a deterioration of human and animal habitats. The most sub­ stantial features of global ecodynamics of the late 20th and early 21st centuries include the rapid increase in world population (mainly in developing countries), increase in the size of the urban population (considerable growth in the number of megalopolises), and increase in the scales of such dangerous diseases as HIV/AIDS, hepatitis, tuberculosis, etc.

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Globalization and Summit Reform : An Experiment in International Governance

This account of the 'L-20 project' describes and analyses a 3-year mobilization designed as an alternative to the political deadlocks preventing progress on critical global issues. The L-20 would include leaders from the existing G-countries, augmented by key regional powers such as China, Brazil, India, South Africa and Egypt. The book traces the origins and findings of the project, which generated a broad array of cutting-edge research and over twenty substantive, action-oriented workshops involving hundreds of experts and practitioners around the world. The workshop series examined in detail the operational possibilities for a Leaders Group addressing a range of issues, including infectious disease control, climate change/global warming, energy security, nuclear proliferation, management of international financial crises, and the provision of safe drinking water and sanitation, to name just a few.

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Globalization and Regional Economic Modeling

Globalization is affecting regional economies in a broad spectrum of aspects, from labor market conditions and development policies to climate change. To understand better how this works, we need both conceptual and methodological contributions. We need new schemes to organize our thinking, direct our attention, and frame thought experiments on the basis of which guidance may be offered. And we need methodological innovations that enable us to carry out studies and thought experiments at levels of spatial and temporal resolution and formal complexity adequate to capture and account for the phenomena that characterize globalization. The chapters of this volume, written by an international cast of eminent regional scientists, represent contributions of both types, in many cases introducing and demonstrating the use of new tools for analyzing and understanding enormous changes underway in regional economies around the world.

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Globalization and Health : Challenges for health law and bioethics

This timely collection explores ethical and legal dilemmas in healthcare arising from globalization. Conflicts between public interests and individual rights, the challenge of regulating professionals and access to health services, and the effects of a global market all feature prominently in contemporary debates in this area. As a result of globalization, issues in health law and bioethics can no longer be understood solely within political boundaries that define traditional notions of individuals and communities. Rather, solutions for emerging problems require a global conception of rights and obligations, including the re-evaluation of ethical frameworks and legal regimes that currently govern exchanges in healthcare. Leading scholars in bioethics, law, medicine and philosophy from various jurisdictions engage these themes in this volume, and demonstrate the need for transnational solutions in a global age of healthcare.

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Globalization and Environmental Challenges : Reconceptualizing Security in the 21st Century

This book contiants chapters address the theoretical, philosophical, ethical and religious and spatial context of security; discuss the relationship between security, peace, development and environment; review the reconceptualization of security in philosophy, international law, economics and political science and for the political, military, economic, social and environmental security dimension and the adaptation of the institutional security concepts of the UN, EU and NATO; analyze the reconceptualization of regional security and alternative security futures and draw conclusions for future research and action.

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Globalization and culture at work : Exploring their combined glocality

Behaviour at work can no longer be stereotyped as global or local – modern or traditional – with very little in-between. Instead work behaviour is a complex interplay between Global and Local values. It takes place in a Glocality. Thus individual achievement co-exists with group aspirations, pay diversity takes place in a social context, teamwork reflects cultural narrative, and labour mobility is bound by community bias. Globalization and Culture at Work: Exploring their Combined Glocality breaks new ground by exploring such glocalities, and the implications they create for managing human potential better. The volume is essential reading for researchers, managers, culturalists and consultants of work behaviour alike.

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Globalisation, Poverty and Conflict : A Critical 'Development' Reader

Is ‘development’ passé? Is it merely a by-product or a ‘trickle down’ effect of economic growth, spurred by globalisation? Will poverty simply diminish with increased global markets? This state-of-the-art critical ‘development’ reader deals with these and related questions. Globalisation, Poverty and Conflict examines the inter-relationships between globalisation, poverty and conflict. It complements current debates in the field of development studies and, in an era in which development fatigue seems to have become more profound than ever before, it brings the importance of development once again to the forefront. Achieving the Millennium Development Goals by 2015 is a concrete target which many governments have agreed to work towards.Whether these goals can be realised is another issue. Nonetheless, the Millennium Development Goals have brought more focused attention to development in the past few years and renewed debate about the relationships between the process of globalisation and widespread poverty and the emergence of violent conflicts. The authors in this edited volume discuss these inter-related and highly controversial topical elements of development in a number of chapters organised around three sets of issues: (1) globalisation, inequality and poverty; (2) governance, civil society and poverty; and (3) resource degradation, institutions and conflict. The contributions represent current thinking on (and practice of) development policy, poverty reduction, the need for multi-level democratic institutions, and the containing and prevention of conflicts. The authors confront the predominant mainstream ideas on ‘development’ and propose alternatives.

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Global Warming - Myth or Reality? : The Erring Ways of Climatology

In the global-warming debate, definitive answers to questions about ultimate causes and effects remain elusive. In Global Warming: Myth or Reality? Marcel Leroux seeks to separate fact from fiction in this critical debate from a climatological perspective. Beginning with a review of the dire hypotheses for climate trends, the author describes the history of the 1998 Intergovernmental Panel on Climate Change (IPCC)

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Global Specification and Validation of Embedded Systems : Integrating Heterogeneous Components

Global modelling and validation is required to master the design of systems made of heterogeneous components. These systems are now omnipresent in our life, and they may be found in several domains such as communications (ex. mobile terminals, optical switches), health (e.g. cardiac stimulators, cochlear implants), transportation (ex. automotive and aeronautical), etc. The main difficulties for their design are modelling and validation of the interactions between different components (hardware, software, analogue, RF, optical and micro-mechanical).

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Global Smoothness and Shape Preserving Interpolation by Classical Operators

This monograph examines and develops the Global Smoothness Preservation Property (GSPP) and the Shape Preservation Property (SPP) in the field of interpolation of functions. The study is developed for the univariate and bivariate cases using well-known classical interpolation operators of Lagrange, Grünwald, Hermite-Fejér and Shepard type. One of the first books on the subject, it presents interesting new results alongwith an excellent survey of past research.

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